446-Killing superbugs with lemons and ghost bacteria

Paper Talk · Jan 30, 2026 · 17m

This research details the creation of PMB@LNV-SyBV, a sophisticated hybrid nanovesicle designed to treat severe bacterial infections like pneumonia and sepsis. By fusing anti-inflammatory lemon-derived vesicles with detoxified synthetic bacterial vesicles, scientists developed a carrier that effectively encapsulates the antibiotic Polymyxin B. This platform utilizes a "neutrophil hitchhiking" strategy, where the body’s own immune cells recognize the vesicles and transport them directly to the site of infection. Once at the target, the vesicles release their cargo to eliminate…