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The Beauty Molecule That Is Changing Everything Featuring Renowned Dr. Perricone · Skin Anarchy

• 0:00
  SPEAKER_00: Hey guys, welcome back to Skin Anarchy.
• 0:03
  SPEAKER_00: This is Zekta, and I have such a remarkable guest with me today.
• 0:07
  SPEAKER_00: I am truly honored and humbled to be hosting him.
• 0:10
  SPEAKER_00: He has been such a visionary and a leader in the space of skin health for so many years.
• 0:15
  SPEAKER_00: And we're gonna be talking about his new book that's coming out now.
• 0:19
  SPEAKER_00: Um so without me ranting too much, please I would love to introduce you guys to Dr.
• 0:23
  SPEAKER_00: Nicholas Pericone.
• 0:24
  SPEAKER_00: Welcome, Dr.
• 0:24
  SPEAKER_00: Pericone.
• 0:25
  SPEAKER_00: It's such an honor to host you.
• 0:27
  SPEAKER_01: Thank you.
• 0:27
  SPEAKER_01: And it's a pleasure um getting to talk with you today and and our audience.
• 0:32
  SPEAKER_01: I'm very excited about the new book.
• 0:34
  SPEAKER_01: So it's just a lot of fun to get to talk about it.
• 0:36
  SPEAKER_00: Yeah, I'm really excited that you're coming out with, you know, you came out with a new book, and I would love to learn about it.
• 0:42
  SPEAKER_00: And I really want to talk about you because you've led the beauty and wellness world through so many scientific evolutions, you know.
• 0:49
  SPEAKER_00: And for me, I mean, your brand was one of the first professional brands that I got my hands on, you know, and I was learning about skin health.
• 0:56
  SPEAKER_00: And it was, it's just it's so inspiring to see this, you know, kind of come full circle for myself.
• 1:01
  SPEAKER_00: So I want to ask you, you know, what really inspired um the beauty molecule, which is the name of the book for everyone listening.
• 1:07
  SPEAKER_00: Um, why was it why is right now the right time for this message?
• 1:11
  SPEAKER_01: Well, it's it's a perfect time because I um um my last book was 10 years ago, and people asked me why this uh long break.
• 1:18
  SPEAKER_01: I said, because really um uh my research, I didn't see anything that was really um uh different from what I uh my initial ideas about inflammation, aging, and disease and all the uh information I have on skin.
• 1:31
  SPEAKER_01: Um but um with my research over the past 10 years, I um was it was kind of really enlightening to uh see what happened in terms of my study.
• 1:41
  SPEAKER_01: So I have an unusual background.
• 1:43
  SPEAKER_01: Um certainly a medical doctor, but I'm also a nutritionist, and I've done original research in nutrition.
• 1:48
  SPEAKER_01: Uh, but this really all started back in medical school when I was uh doing my histopathology and looking at uh different um uh pieces of pathology under the microscope and um looking at a squamous cell cancer and it was surrounded by inflammation.
• 2:02
  SPEAKER_01: And um it and then universally, as I kept on going with my career and did my dermatology residency, a lot of time spent in the microscope and uh everything uh was associated with uh visible inflammation.
• 2:13
  SPEAKER_01: And so at that time I really came up with the um inflammation aging disease theory.
• 2:19
  SPEAKER_01: That was like almost 25 years ago, but it was um it was not well received, uh, as you know, um in medicine and science, um new ideas are are not met with uh curiosity or met with rejection.
• 2:32
  SPEAKER_01: And so it seems to me that, at least my experience, I don't mean to offend anybody, but um science seems to be more like um a religion uh than science, because there's a set of ideas.
• 2:43
  SPEAKER_01: And um, and very much, and if you fall outside of the belief system, instead of getting um open-mindedness and people looking at it, uh we have an emotional response.
• 2:53
  SPEAKER_01: And so um it was very um pretty bad uh time back then, um, in terms of what I was getting from the medical community, scientific community.
• 3:03
  SPEAKER_01: Uh it was just rejection and a lot of criticism.
• 3:06
  SPEAKER_01: Now that it's mainstream, of course, it's it's accepted, and so it's a lot easier to talk about this, but um this but science keeps on moving forward, and there's always going to be new ideas.
• 3:14
  SPEAKER_01: So what we need to do is probably change our attitude and start being scientists.
• 3:18
  SPEAKER_01: Where we want curiosity, uh, we want to look at the data, and we don't just reject it on an emotional basis.
• 3:25
  SPEAKER_01: So that's where we're coming from.
• 3:26
  SPEAKER_01: So I'm I'm really excited about this book because uh with the fact that we now know that uh inflammation uh is at the basis of all Western diseases and including the disease of aging.
• 3:37
  SPEAKER_01: And uh when I first talked about aging as a disease, uh, very, very negative response.
• 3:42
  SPEAKER_01: Uh so here we are.
• 3:44
  SPEAKER_01: That's the uh that's the downside, but there's 99% bright light and and a lot of good things to talk about today.
• 3:50
  SPEAKER_00: Yeah, no, this is uh everything you said hits home for me.
• 3:54
  SPEAKER_00: Um I've I I've never understood this either.
• 3:57
  SPEAKER_00: You know, people not only do they reject it, but it's almost looked at as like pseudoscience, you know, when you introduce something truly novel in the scientific community and it it's really kind of jarring in that way for I think many scientists because you don't ever get to truly explore that idea in a in a timely manner.
• 4:15
  SPEAKER_00: 20 years down the road, you see now it's become a buzzword.
• 4:18
  SPEAKER_00: And I feel like inflammation, exactly what you said.
• 4:20
  SPEAKER_00: Now I, you know, I'm looking at the industry and everyone's talking about inflammator aging.
• 4:24
  SPEAKER_00: And unfortunately, even now, some of the conversations that take place that I've noticed at least, I don't know if you've um experienced this, but though some of those conversations are actually poorly rooted in the science they're referencing.
• 4:35
  SPEAKER_00: Talking about inflammation in a very isolated way rather than what you were uh you're talking about, where aging can be referred to as a disease, inflammation can be, you know, talked about in a more broader scope where it's impacting every organ, we still don't see that enough.
• 4:48
  SPEAKER_00: But here we are with the buzzword, you know, that people are using now.
• 4:52
  SPEAKER_01: Yeah, well, one of the things too is of course um inflammation aging theory came up quite a while ago.
• 4:56
  SPEAKER_01: Um what I what I was looking at was yes, we know that the um the immune system certainly changes as we get older and that and inflammation starts popping up.
• 5:04
  SPEAKER_01: But I um, because of my background of being a medical doctor and a nutritionist, I found that um it was that basically inflammation is tied very closely to the metabolic system.
• 5:14
  SPEAKER_01: And if if the metabolist, uh metabolic system is is awry, then you're gonna need a lot more inflammation.
• 5:19
  SPEAKER_01: And that's what I've been talking about all these years.
• 5:22
  SPEAKER_01: Um, and so I when I developed the first um anti-inflammatory diet, once again it was easy for me being a nutritionist, and then actually testing it and then looking in the old days at said rates changing, and then the newer days uh we're using C reactive protein, uh, we can see some really miraculous things.
• 5:38
  SPEAKER_01: And I get um uh emails and letters from uh physicians or friends of mine and people who've been on the anti-inflammatory diet.
• 5:45
  SPEAKER_01: And they talk about um, in fact, one of my colleagues that I was in my residency with uh just sent me a really nice note.
• 5:50
  SPEAKER_01: He said um he was thrilled he um uh his C reactive protein was up around seven or eight.
• 5:57
  SPEAKER_01: He did the anti-inflammatory diet, and he said, my latest number is 0.73.
• 6:02
  SPEAKER_01: And so this is another physician and someone I did my residency with.
• 6:05
  SPEAKER_01: So uh I'm really uh happy that this is now uh getting to be mainstream because we've got to focus on inflammation at the basis of all diseases, including the disease of aging.
• 6:16
  SPEAKER_01: Uh then, of course, being a dermatologist, um looking under the microscope and seeing inflammation, I then said, well, I've got to set my sights on creating topicals um that will have anti-inflammatories that have to be benign.
• 6:28
  SPEAKER_01: And uh what happened too is I had a lot of um uh, I think fortuitous things happening.
• 6:33
  SPEAKER_01: When I was an intern in pediatrics at Yale, there was a study going on in another pediatric center, and they were looking at um at asthma.
• 6:42
  SPEAKER_01: And what they did is they did an interesting study, a double-blind placebo control study, uh, but they gave the children um um vitamin C in form of chewables, about 500 milligrams twice a day, which was a huge dose for children.
• 6:54
  SPEAKER_01: And uh when they broke the code, um 50 they had a reduction, 50% of the uh inflammatory airway attacks.
• 7:03
  SPEAKER_01: And so that burned in my memory that so vitamin C, antioxidant, anti-inflammatory, then started looking at all the other categories over the years.
• 7:12
  SPEAKER_01: And so I came up with uh a really nice group of categories to use as I started formulating my topicals and things like um as scorable pomate, which is vitamin C in a uh fat-soluble form.
• 7:25
  SPEAKER_01: Alphalopoic acid was an incredible find.
• 7:28
  SPEAKER_01: Um, it's a universal antioxidant, both water soluble and fat-soluble.
• 7:32
  SPEAKER_01: And so these went into my products, but also at the same time, I had to come up with ways to basically deliver this into the skin uh because you're putting on creams that just sit on top, it does nothing.
• 7:43
  SPEAKER_01: And so I came up with uh certain uh formulas.
• 7:46
  SPEAKER_01: And I, if I changed the ratio, I could actually basically target the depth of penetration.
• 7:52
  SPEAKER_01: And so I wanted to get into skin and dermis.
• 7:54
  SPEAKER_01: I did not want to get into dermal vasculature.
• 7:56
  SPEAKER_01: And so I created this.
• 7:58
  SPEAKER_01: But what happened is I started a second company called Transdermal Biotechnology because I found that I can get most biologically active uh products, especially peptides, uh, into the dermal vasculature, which then circulates.
• 8:10
  SPEAKER_01: Um, and it's a liquid crystal that doesn't break down until it gets to the cell membrane.
• 8:15
  SPEAKER_01: And so what we could do, it would circulate, it wouldn't be broken down by the enzymatic systems.
• 8:19
  SPEAKER_01: And we also get the blood-brain barrier.
• 8:22
  SPEAKER_01: So uh transdermal has been enormous.
• 8:23
  SPEAKER_01: I have several, probably 25 or 30 patents in this area.
• 8:27
  SPEAKER_01: And so I look upon this as a evolution of not just treating skin, but then systemic and then as a nutritionist and the things that we can do.
• 8:35
  SPEAKER_01: So very exciting, still exciting time for me.
• 8:37
  SPEAKER_01: There's so much more to be done in terms of using basically peptides that have biologic activity, but there's no way to deliver them.
• 8:44
  SPEAKER_01: But with the transdermal system, we can do that.
• 8:47
  SPEAKER_01: So it's it just opens up a whole new field for me.
• 8:49
  SPEAKER_00: I'm really excited to hear about that because I feel like when it comes to topical application, there are so many redundancies right now.
• 8:56
  SPEAKER_00: You know, when I look at the world with all the products and all the devices and all that, but but I think there needs to be, you know, this shift that occurs where we start looking at, you know, I I for me, I hate hearing the word, for example, like everyone says peptides and no one talks about the the role that they play, right?
• 9:12
  SPEAKER_00: And like where they what does a peptide actually do?
• 9:15
  SPEAKER_00: You know, how does that molecularly enhance the, you know, the actual biology?
• 9:20
  SPEAKER_00: And so there's a lot of question marks still, even though we're evolving.
• 9:22
  SPEAKER_00: And so it's very, very exciting.
• 9:24
  SPEAKER_00: Now I want to ask you about, you know, in the book, it feels like a true shift that's taking place because you're talking about, you know, from treating signs of aging to now truly understanding what fuels aging.
• 9:34
  SPEAKER_00: Um, how did mitochondrial health become your new frontier?
• 9:38
  SPEAKER_01: Very interested in the mitochondrial function.
• 9:40
  SPEAKER_01: Um, and uh my last um uh book many years ago um came to the conclusion that we age in the mitochondria.
• 9:47
  SPEAKER_01: So the mitochondria, of course, is our um organelle that uh produces energy, but it also has so many other functions.
• 9:54
  SPEAKER_01: It it uh releases um um certain um chemicals and and and um other other ingredients that actually then uh do things such as uh creating um uh basically whether we we if we have cells that are dormant, uh we want to get rid of those because many of those cells they may be dormant, but they're constantly producing these pro-inflammatory uh chemicals.
• 10:16
  SPEAKER_01: And so um, and so we if you start looking at total body um uh burden of inflammation, uh you realize that a lot of this is coming from these so-called um uh cells that are supposed to be just kind of sitting there, but they're not, they're active.
• 10:32
  SPEAKER_01: And so it's very important we get into autophagy and mitophagy.
• 10:35
  SPEAKER_01: So I became very interested in mitophagy and started looking at substances that could enhance mitophagy because we have to get rid of those mitochondria.
• 10:43
  SPEAKER_01: But the thing is the body is so efficient, it breaks up mitochondria, but using those those parts that and all of those various aspects, it then makes new mitochondria, then also gets rid of these um uh sedentary cells that are still active.
• 10:56
  SPEAKER_01: So this is why I got so interested in the mitochondria, because we age in the mitochondria.
• 11:01
  SPEAKER_01: And so it's been this whole thing I've been doing.
• 11:03
  SPEAKER_01: And so this research I've done over the past 10 years, uh, it all came down to inflammation, of course, but one molecule in the body.
• 11:12
  SPEAKER_01: And so I had to name the book the beauty molecule, because it's this one molecule, which is acetylcholine.
• 11:17
  SPEAKER_01: We're all aware of that as physicians, uh, you know, it's a neurotransmitter.
• 11:21
  SPEAKER_01: But what I found is it's also tremendously active as an anti-inflammatory because when it locks onto things like the alpha receptors in the on the central nervous system, it turns off inflammation centrally.
• 11:33
  SPEAKER_01: And so we want to do that.
• 11:35
  SPEAKER_01: And so I in this book I want to talk about acetylcholine and different ways that we can elevate in our body through diet, uh, through supplements, um, and something as simple as um doing something like meditation.
• 11:46
  SPEAKER_01: And also, there are also pharmacologic um uh chemicals that can be also very helpful too.
• 11:52
  SPEAKER_01: So, what really intrigued me was uh an excellent article.
• 11:55
  SPEAKER_01: It was an animal study.
• 11:57
  SPEAKER_01: And basically they looked at um um these animal models, they were using uh mice, but they would gave they would give them um uh basically heart disease by giving them a high-fat diet.
• 12:07
  SPEAKER_01: And then looking under the electron microscope, we could look at the mitochondria and those beautiful little footballs with those um uh with those vertical lines.
• 12:15
  SPEAKER_01: Uh the football is now distorted into almost a kind of a circular or a sphere, and all of those lines where that means uh where the um electron transport is taking place are now blurred.
• 12:26
  SPEAKER_01: And then what they did is they elevated acetylcholine by giving these animals a um a drug.
• 12:33
  SPEAKER_01: It's called peridostigmine, it's used for myasthenia gravis.
• 12:36
  SPEAKER_01: And um they gave them a dose and they followed it for four months.
• 12:40
  SPEAKER_01: And then if you look at the electron microscopy at this point, all of those, all of those mitochondria are now the perfect little footballs with the vertical lines.
• 12:48
  SPEAKER_01: So it was so impressive to see that just by elevating this molecule acetylcholine by using an acetylcholine esterase inhibitor can repair the mitochondria.
• 12:58
  SPEAKER_01: And then so this brought me down a road that was just amazing.
• 13:02
  SPEAKER_01: So things that we can do, for example, when we meditate, um, and we don't have to meditate for long periods of time, we upregulate um the release of acetylcholine in just about every cell in our body.
• 13:14
  SPEAKER_01: And so by doing that, we can meditate our way to repairing the mitochondria.
• 13:18
  SPEAKER_01: It's just phenomenal to think about it, because if you look at people who discover meditation and then they're doing it, and then you see them a year later, they look like different people.
• 13:27
  SPEAKER_01: They're younger, I mean they're more vibrant.
• 13:29
  SPEAKER_01: And so there's a real physiologic reason for this in the real world, they're repairing their mitochondria.
• 13:34
  SPEAKER_01: So we have this in this book, we have all of these strategies: food, supplements, meditation, and many other others, pharmacological agents we could use.
• 13:43
  SPEAKER_01: And so I think this is going to be hugely helpful to people when they see this because it's all new.
• 13:48
  SPEAKER_01: And of course, um, it's interesting that many years ago when I chose the topicals, I used precursors of uh acetylcholine.
• 13:56
  SPEAKER_01: And um so it acts uh as a penetration enhancer, but it also elevates levels of acetylcholine.
• 14:02
  SPEAKER_01: So we've been there for many years, and that's why my products have been so successful.
• 14:06
  SPEAKER_01: But now when we truly know the mechanism that's here, we can now pinpoint this.
• 14:10
  SPEAKER_01: So if we can normalize metabolism, we shut down inflammation because inflammation is always at the basis of aging in all age-related diseases.
• 14:19
  SPEAKER_01: And so I'm excited about that because we now we have different methods of approaching this.
• 14:23
  SPEAKER_01: We don't just have the anti-inflammatory diet, but we have certain supplements, we have certain ways of eating, and we can even use some pharmacologics that are pretty much benign uh to do this.
• 14:33
  SPEAKER_01: And of course, uh I think the biggest um issue I'm always looking at isn't is obviously uh neurologic decline.
• 14:39
  SPEAKER_01: And it all takes place in central nervous system, the brain, in inflammatory reactions.
• 14:44
  SPEAKER_01: And so things that we eat cause a cascade of inflammation.
• 14:48
  SPEAKER_01: But in the brain, of course, this goes on all of the time.
• 14:51
  SPEAKER_01: So by using these strategies, we can rapidly reduce inflammation systemically, especially in the central nervous system, and maintain our our clearness and the cognitive function, you know, right to the last few days of our life.
• 15:05
  SPEAKER_01: And so that's probably one of the most important things I'm looking at.
• 15:08
  SPEAKER_00: That's so fascinating that you've tied um so much together with acetylcholine.
• 15:13
  SPEAKER_00: That's act that's so brilliant because we never we never even talk about it, you know.
• 15:17
  SPEAKER_00: I mean, I think about I think back to like medical school, right, and training, and we we barely learn about acetylcholine, you know, it's it's like kind of mentioned and then we just forget about it.
• 15:26
  SPEAKER_00: But the immense role that it plays, like you you explained, I mean, you know, in every part of the system, it's it's basically the parasympathetic nervous system that's being activated here and then releases it.
• 15:36
  SPEAKER_00: So we when you think about that, we people always kind of brush it off as like rest or digest.
• 15:41
  SPEAKER_00: But really, I mean, if you if you really dig deeper into that concept, it is kind of trying to, you know, I guess dampen the inflammation throughout the body, right?
• 15:51
  SPEAKER_00: Is that would that be a correct way to think about it?
• 15:54
  SPEAKER_01: Exactly.
• 15:54
  SPEAKER_01: That's exactly the way we should think about it because it just puts it in the right direction and it doesn't have to be sophisticated and it's not complicated.
• 16:01
  SPEAKER_01: So um, and we we look at so many different examples.
• 16:04
  SPEAKER_01: We know that um when we have moderate exercise, of course, it elevates levels of acetylcholine because it's the way our muscles contract.
• 16:11
  SPEAKER_01: Um and then so many other things that we do.
• 16:13
  SPEAKER_01: And of course, rest is also very important and getting a good night's sleep.
• 16:18
  SPEAKER_01: So uh so we have all of these very, very simple, non-toxic, inexpensive ways of approaching this.
• 16:24
  SPEAKER_01: And so um I was so successful with my anti-inflammatory approach to life, the anti-inflammatory diet, what it can do for people, and then my anti-inflammatory supplements and the topicals, um, I said, well, what more can we do?
• 16:38
  SPEAKER_01: Well, we now we have to elucidate what is the mechanism here, and this is what this book is all about.
• 16:42
  SPEAKER_01: But it's interesting and it's fun because there's so many ways of elevating acetylcholine.
• 16:47
  SPEAKER_01: And so if you just think about those alpha-7 receptors in the brain, and and when you lock on to that with acetylcholine, it turns off inflammation.
• 16:56
  SPEAKER_01: But at the same thing, there are other things that do this.
• 16:59
  SPEAKER_01: And so I have a pretty good amount of time spent talking about nicotine.
• 17:04
  SPEAKER_01: Uh, because we have the so-called nicotinic receptors in the brain, but those are the ones that we want to activate because it turns off inflammation.
• 17:11
  SPEAKER_01: So obviously the problem is most of people are getting um nicotine or through uh smoking.
• 17:16
  SPEAKER_01: Uh, but there's so many other ways to get it.
• 17:19
  SPEAKER_01: And uh there's so much data that's popping up now with all kinds of uh um diseases, a full spectrum of people using the nicotine patch helps with uh prevents um cognitive decline, helps with Parkinson's disease, helps with normalizing your metabolism.
• 17:35
  SPEAKER_01: And we keep on going down the road.
• 17:37
  SPEAKER_01: So they're all here in the book.
• 17:39
  SPEAKER_01: These are all different ways we go about it.
• 17:41
  SPEAKER_01: And I certainly would love to see everybody stop smoking, but we don't want to give up nicotine.
• 17:45
  SPEAKER_01: And so we have different things.
• 17:47
  SPEAKER_01: And what I do is when I have work to do, I get some Nicaret gum and I you know chew a little bit and put it up in my cheeks and just leave it there.
• 17:53
  SPEAKER_01: I forget about it.
• 17:54
  SPEAKER_01: You get incredible clarity and energy.
• 17:57
  SPEAKER_01: Um, and this should be done every day.
• 17:59
  SPEAKER_01: And I think the patches are probably a better way.
• 18:01
  SPEAKER_01: I haven't tried them self-mite myself yet, but I think I'm gonna move to that.
• 18:05
  SPEAKER_01: So we have all of these wonderful ways of doing this that are non-toxic, inexpensive, and we can change things.
• 18:10
  SPEAKER_01: And the other thing was inflammation was everything.
• 18:13
  SPEAKER_01: So I I was said someday I would like to discover what I call the magic bullet.
• 18:17
  SPEAKER_01: And it would have to read three criteria.
• 18:19
  SPEAKER_01: It would have to be non-toxic, have to be inexpensive, easy to use, and readily available.
• 18:26
  SPEAKER_01: So about 10 years ago, I was reading an article in um uh very uh prestigious journal Nature and Medicine, and they were talking about hydrogen water and the fact that it acts as an antioxidant.
• 18:37
  SPEAKER_01: And I thought this doesn't throw them right to me.
• 18:39
  SPEAKER_01: I mean, um, you know, H2 is a nonpolar molecule, it doesn't interact.
• 18:44
  SPEAKER_01: Um, but I forgot about some things like we have dehydrogenases in our body.
• 18:48
  SPEAKER_01: So uh it was coming out of uh Japan.
• 18:50
  SPEAKER_01: Uh so I took a trip to Tokyo, I met with the scientists, I met with the manufacturers, had been there for like 20 or 30 years and never left the country.
• 18:58
  SPEAKER_01: And I was still skeptical.
• 19:00
  SPEAKER_01: I came back and I did my own study.
• 19:02
  SPEAKER_01: And what I wanted to do was I talked to a partner of mine.
• 19:05
  SPEAKER_01: Unfortunately, he passed away, um Dr.
• 19:07
  SPEAKER_01: Peter Poglaci, a brilliant guy, should have had a Nobel Prize, by the way.
• 19:11
  SPEAKER_01: And I said, Look, Peter, I'm looking for a way to quantify something about hydrogen water.
• 19:14
  SPEAKER_01: And one of the things they're touting is that it gives them, gives you energy.
• 19:19
  SPEAKER_01: So I said, Well, what can we do with this?
• 19:21
  SPEAKER_01: He said, Well, Nick, the good news is he said the only molecule that fluoresces in the skin under a certain frequency is NAD.
• 19:27
  SPEAKER_01: Well, that's the molecule, right, to look at for energy.
• 19:30
  SPEAKER_01: So we went ahead and we um had the um uh the LEDs made up at the right frequencies, and we then uh brought people into the study with double blind placebo controls.
• 19:41
  SPEAKER_01: We just took a little strap, a leather strap with the um LED, and we had the um basically looking at the fluorescence, and then we have the computer figure this out.
• 19:50
  SPEAKER_01: So I was there and we once it was double blind plus, so we had just plain cans of water, we didn't know what they were, and handed them out to the um the group.
• 19:58
  SPEAKER_01: It wasn't a huge, what it was just uh, you know, like 50 people.
• 20:01
  SPEAKER_01: But it so I'm sitting there and say it's gonna be a long day.
• 20:04
  SPEAKER_01: You've got to drink the water, you know, it has to go in the mouth, esophagus, stomach, get into the bloodstream, circulate, get into the skin cells, and get into the mitochondria.
• 20:12
  SPEAKER_01: So I'm putting my feet up and looking at the computer, and the first person that I don't know whether they're drinking plain water or hydrogen water, and I'm looking at the computer, and in two and a half minutes I'm seeing a movement.
• 20:22
  SPEAKER_01: And I just kept on watching it, and in 15 minutes it was up 12.5%.
• 20:27
  SPEAKER_01: Um, I said, this is phenomenal.
• 20:30
  SPEAKER_01: And so once I saw that, I said, well, hydrogen water is real and I've got to do it correctly.
• 20:35
  SPEAKER_01: So I went ahead and started putting this together.
• 20:37
  SPEAKER_01: Um, I wanted to make sure that we um could get hydrogen in the water at what we thought were therapeutic uh levels, which came out of Japan.
• 20:44
  SPEAKER_01: It had to be above one part per million.
• 20:46
  SPEAKER_01: And it had to be stable and it's very, you know, it's a tiny molecule.
• 20:49
  SPEAKER_01: You can't put it in glass or plastic.
• 20:51
  SPEAKER_01: It's got to be in a sealed can, it's got to be aluminum, it's got to have a polymer to protect the aluminum.
• 20:56
  SPEAKER_01: And we had several weeks um at universities with 100% hydrogen um on these plain pieces of um aluminum with a polymer to see if it leaked.
• 21:05
  SPEAKER_01: And so we got the cans right, and then we I bought the machines from um uh Japan.
• 21:10
  SPEAKER_01: This was a very big expense.
• 21:12
  SPEAKER_01: So this was a capital equipment, and we went ahead and spend the money and we produced our own hydrogen.
• 21:17
  SPEAKER_01: And um we now have retains of those cans that are six and a half years old, and we haven't lost one molecule of hydrogen.
• 21:24
  SPEAKER_01: So um the hydrogen water company, which I started, is now out there.
• 21:27
  SPEAKER_01: We're just ramping up now.
• 21:29
  SPEAKER_01: Um, it's great to be ahead of your time in science.
• 21:32
  SPEAKER_01: Uh, and to well, it's a two-edged soil, as we both know.
• 21:35
  SPEAKER_01: But when you're talking about a uh product that we now so far invested$12 million in, um, and you have no sales because the world hasn't caught up, now it's caught up.
• 21:45
  SPEAKER_01: And so you're gonna see things changing out there.
• 21:47
  SPEAKER_01: And probably one of the most impressive uh studies I've seen, it came out of India and it was done by the Hydrogen Foundation.
• 21:55
  SPEAKER_01: Um, and uh they basically took these people with metabolic syndrome.
• 22:00
  SPEAKER_01: And uh they were told, listen, we don't want you to change anything.
• 22:03
  SPEAKER_01: We you're not exercising, don't start, don't change your diet, just be you.
• 22:07
  SPEAKER_01: And I don't think there's much of a chance of people changing their diet if they have metabolic syndrome, by the way.
• 22:12
  SPEAKER_01: And uh, we gave them hydrogen water twice a day.
• 22:14
  SPEAKER_01: And uh, but it was uh also double-blind, placebo controlled.
• 22:18
  SPEAKER_01: At the end of 24 weeks, when that code was broken, 100% of those people with metabolic syndrome who were drinking the hydrogen water uh uh were completely no longer uh could be uh basically classified as metabolic syndrome, and all those who did not still had metabolic syndrome.
• 22:36
  SPEAKER_01: So I said, that's it.
• 22:37
  SPEAKER_01: This is so important.
• 22:39
  SPEAKER_01: Uh, you know that metabolic syndrome, all of the Western diseases are downstream.
• 22:43
  SPEAKER_01: And we can interrupt this by drinking water twice a day.
• 22:46
  SPEAKER_01: I mean, how many patients do you see and you say, look, you have metabolic syndrome, diet, exercise?
• 22:51
  SPEAKER_01: It never happens.
• 22:51
  SPEAKER_01: I mean it's difficult for people, but they can drink two cans of hydrogen water a day, and we can change that.
• 22:57
  SPEAKER_01: So my belief is you know, the back of the envelope, you know, um, looking at the numbers, I think in in three years, if we get the cop population drinking hydrogen water twice a day, we could drop the healthcare cost by a third in this country, and five years probably by 50%.
• 23:12
  SPEAKER_00: Wow, that is remarkable.
• 23:14
  SPEAKER_00: That's really, I mean, that's so fascinating to me.
• 23:17
  SPEAKER_00: And then, you know, I'm I'm curious what your thoughts are then on this idea or the the way that hydration is perceived in our, you know, in our world, both on the medical side as well as, you know, consumers, like, you know, because I feel like with high hydration is talked about so much, right?
• 23:33
  SPEAKER_00: Overall, I think in health and wellness, especially when we come to the realm of like trying to have, you know, mass education for people, everyone talks about hydration.
• 23:42
  SPEAKER_00: But you know, what do you think there some misconceptions are that are out there about it?
• 23:46
  SPEAKER_01: Well, certainly hydration is critical.
• 23:48
  SPEAKER_01: And um, you know, everybody, and the problem is the first mechanism doesn't work very well until we're dehydrated by about one or two percent.
• 23:56
  SPEAKER_01: And and that's that's not not acceptable.
• 23:58
  SPEAKER_01: So since all chemical reactions take place, including metabolic ones, it's important to get enough water.
• 24:03
  SPEAKER_01: Uh, and so I always advocated, you know, eight, you know, eight, eight-ounce glasses of uh kind of spring water every day uh as part of the anti-inflammatory diet.
• 24:12
  SPEAKER_01: Um, and so now that we have hydrogen water, uh, which is just an amplified you know effect of this, then that that becomes critical.
• 24:19
  SPEAKER_01: But yes, hydrating is critically important.
• 24:22
  SPEAKER_01: But now that it's catching on here with hydrogen water, it's gonna change things for us very rapidly.
• 24:27
  SPEAKER_01: And you know, it's not just a metabolic syndrome.
• 24:29
  SPEAKER_01: Um, and um, I don't know, did we ever send you a case of the water?
• 24:32
  SPEAKER_01: Because I wanted you to experience it.
• 24:34
  SPEAKER_01: But it's interesting.
• 24:35
  SPEAKER_01: Um, I've given out so many cases over the seven or eight years, um, and uh everybody had a certain deficit and they come back to me, and it seemed to help.
• 24:43
  SPEAKER_01: So I don't want to start talking about it.
• 24:44
  SPEAKER_01: It sounds like snake oil because it works on everything.
• 24:47
  SPEAKER_01: Um, but it's it's real.
• 24:48
  SPEAKER_01: And so I I'm just so happy that this is gonna happen now.
• 24:51
  SPEAKER_01: It's gonna happen, and I'm talking to major distributors here in the country, getting hydrogen water out to everybody.
• 24:57
  SPEAKER_01: It's gonna be the new drink.
• 24:58
  SPEAKER_01: It's so clean, it's non-toxic, and it's not expensive.
• 25:02
  SPEAKER_01: So this is gonna be a game changer.
• 25:03
  SPEAKER_01: And it all comes down to reducing inflammation.
• 25:06
  SPEAKER_01: But I want to focus right now once again on metabolic metabolics and inflammation.
• 25:11
  SPEAKER_01: They're so closely tied.
• 25:13
  SPEAKER_01: And so when you can when you can normalize metabolism through the various receptors, the GIPs, the LP1s, all the others, um, you actually have this change on a cellular level.
• 25:24
  SPEAKER_01: And so, and everybody was always skeptical about this.
• 25:27
  SPEAKER_01: So you're sure it's the metabolism, you're sure it's not just the nutrients and what you're giving in the anti-inflammatory diet.
• 25:32
  SPEAKER_01: So then comes up these um new peptides, um, um, and uh like uh uh um terzapatide.
• 25:40
  SPEAKER_01: And so I'm looking at this and I'm looking at patients and I'm looking at data, and it is without a doubt the best anti-inflammatory I've seen in my entire career.
• 25:51
  SPEAKER_01: Why is that?
• 25:52
  SPEAKER_01: Because it normalizes metabolism.
• 25:55
  SPEAKER_01: It hits all of those receptor groups that happen when you're eating the right foods, only it does it in a pharmacological manner.
• 26:01
  SPEAKER_01: So it's very powerful.
• 26:02
  SPEAKER_01: So I wrote a letter to uh Lily about two years ago.
• 26:05
  SPEAKER_01: I said, you've got to start extending your patent.
• 26:07
  SPEAKER_01: You've got to talk about it's this is gonna reduce cognitive decline, it's gonna be cardioprotective, uh, hepatoprotective, um, it's gonna be anti-cancer, it's gonna do everything.
• 26:19
  SPEAKER_01: And they have all those patents now filed, and you're gonna see them coming out with new products every day, and it's just it is phenomenal.
• 26:25
  SPEAKER_01: So when I see patients on these on these various uh things like uh terzapatite, yes, they lose weight, and it's important that they eat enough protein because you see a lot of protein wasting and it look because you just lose your appetite.
• 26:38
  SPEAKER_01: But if you have an adequate protein, what you see is yes, they're you're impressed they lose weight, but they all look 10 years younger.
• 26:46
  SPEAKER_01: Their skin is now rejuvenated, they're you know, they're just different people, and it also has some kind of effect on the central nervous system because it gets rid of all kinds of issues in terms of um uh of addictions.
• 27:00
  SPEAKER_01: Uh, but it's not it's not just chemical addictions, they also uh works on things like um gambling addictions.
• 27:07
  SPEAKER_01: I mean, it's just incredible.
• 27:09
  SPEAKER_01: And so, you know, I have all these new theories about what's going on in the central nervous system.
• 27:13
  SPEAKER_01: And I've studied this over and over again.
• 27:16
  SPEAKER_01: As inflammation goes up in the brain, all the neurotransmitters are are not in the right ratio.
• 27:22
  SPEAKER_01: And so uh what you see is just other problems.
• 27:24
  SPEAKER_01: There's anxiety, there's depression, there's just a number of things happening, and of course, cognitive climb.
• 27:30
  SPEAKER_01: And that's the biggest thing we're facing in our healthcare system.
• 27:32
  SPEAKER_01: We have, you know, the the baby boomers born in the the late 40s and early 50s.
• 27:37
  SPEAKER_01: I mean, they're a huge population.
• 27:40
  SPEAKER_01: And uh if they move uh at the standard way, it's gonna break the healthcare system.
• 27:45
  SPEAKER_01: And this can be this can be stopped.
• 27:47
  SPEAKER_01: Anti-inflammatory diet, drinking hydrogen water every day, there's so many things.
• 27:51
  SPEAKER_01: And so what I'm saying is that my whole theory of validation came through these these peptides because they're the magic.
• 27:59
  SPEAKER_01: They hit those receptors and then it turns off inflammation.
• 28:03
  SPEAKER_01: And um, if you're ever interested in anti-aging, you'd want to be on this.
• 28:07
  SPEAKER_00: Yeah, you know, this is very, very fascinating for me because I'm hearing a lot, you know, when we talk about anti-aging, especially in the context of, you know, like, you know, prolonging lifespan, you know, all this longevity talk, there's a lot of buzz around epigenetics right now, for example.
• 28:24
  SPEAKER_00: However, for me, I've I'm still stuck, you know.
• 28:28
  SPEAKER_00: I think in what everything that you're speaking of with this antioxidant potential, right, of different uh molecules.
• 28:35
  SPEAKER_00: I am still stuck there because I feel like that is really the the crux of it.
• 28:40
  SPEAKER_00: I mean, people talk about epigenetics and it's tied to inflammation.
• 28:44
  SPEAKER_00: What are your thoughts on that?
• 28:45
  SPEAKER_01: Just obvious.
• 28:46
  SPEAKER_01: It's really obvious.
• 28:47
  SPEAKER_01: And yes, you get genetic changes and you get epigenetic changes.
• 28:50
  SPEAKER_01: But if we take the anti-inflammatory diet, just doing that at a in a you know a fairly long period of time, we're going to slow the aging process down by a third.
• 29:00
  SPEAKER_01: Um, and not only that, and and and of course the pathology goes with it is skewed even more in the direction of helping us here.
• 29:08
  SPEAKER_01: So I yes, I think they were there.
• 29:09
  SPEAKER_01: And now with the fact that we know that these certain peptides that affect metabolism, that's the button we're pressing.
• 29:16
  SPEAKER_01: And so what I'm hoping to see is um instead of injectables, um, I spent a lot of time with my transdermal company because um I like to use biologically active peptides, but they have to get into the system.
• 29:28
  SPEAKER_01: So if we took these uh peptides and they're small enough to get into um the blood system, instead of giving a bolus once a week with an injection, you have smaller doses using on a daily basis.
• 29:38
  SPEAKER_01: I'm also doing a study right now to see if there's very low amounts like 0.01 or 0.05, but for a topical to see if it rejuvenates skin, and it looks like it's it's happening.
• 29:47
  SPEAKER_01: Wow.
• 29:48
  SPEAKER_01: So um, you know, we're there and we have this.
• 29:51
  SPEAKER_01: The other thing is this this business of muscle wasting, yes, you see it um a lot.
• 29:55
  SPEAKER_01: And uh, whether it was Ozempic, um, I actually like um a tur's appetite better because it hits two of the uh receptors.
• 30:02
  SPEAKER_01: Uh, but all you have to do is make sure you get adequate protein.
• 30:04
  SPEAKER_01: And when you do, what you see is um you actually get increased muscle mass from very little from little exercise.
• 30:12
  SPEAKER_01: And that makes sense because you're normalizing your metabolism, and so everything's working better.
• 30:17
  SPEAKER_01: The endocrine system's working better, the central nervous system's working better.
• 30:20
  SPEAKER_01: Now, as far as antioxidants go, I'm a big fan, but you know, the problem is people are taking too much.
• 30:24
  SPEAKER_01: And and so we know about oxidative stress, but very few people know about this um stress that you get from uh antioxidants, and so we better curtail that to a great extent.
• 30:36
  SPEAKER_01: And if we do this correctly, use the diet and subsupplements with anti-inflammatory activity, but not not huge amounts that people are taking now.
• 30:44
  SPEAKER_01: And so this reductive stress is as real and as damaging as oxidative stress.
• 30:49
  SPEAKER_01: So we need to know this.
• 30:50
  SPEAKER_01: And if we if we balance this, we're do we're doing well.
• 30:53
  SPEAKER_01: And I can tell you from all the people I work with when I'm, you know, in any way.
• 30:57
  SPEAKER_01: So I think the answer right now is like hydrogen water.
• 31:00
  SPEAKER_01: Um, I I would like to see these um uh these peptides like trzapatite and others um utilized, but not in such a powerful way where they're getting these boluses.
• 31:11
  SPEAKER_01: Now it's great for weight loss, I agree, and it's good, but we want to maintain muscle mass and we want to be able to do this in a physiologic manner.
• 31:17
  SPEAKER_01: Yeah, but that is this is the future, and I'm telling you that uh when I say that if we can get the country drinking hydrogen water, which is a real mild way of doing this, but if you also had other people with obesity problems and that and are using that as well, you know, we are gonna just change, change the world in terms of how we approach medicine.
• 31:35
  SPEAKER_00: No, absolutely.
• 31:36
  SPEAKER_00: I'm I'm you know, very much, trust me, I'm very much convinced of it because I think that there is um there's so much tied to this, not just about, you know, obviously with aging, but then also understanding very, very critical diseases that we still don't have answers to, you know, and it's a lot of it has to do with catabolic events that are taking place in the body, and it really makes you wonder about what truly is catabolism, you know, what is what triggers it, right, in certain states.
• 32:02
  SPEAKER_00: I mean, you spoke about protein and how there's protein um breakdown that's happening and protein wasting in people who are not supplementing, but then it that takes my brain to like, well, there's a lot of different disorders that I think you could also apply the same concept to, you know.
• 32:18
  SPEAKER_00: So I think if we do apply this approach, it could be very revolutionary for medicine at large, you know, not just uh, you know, from the the lens of yeah, we're looking at longevity and we're looking at aging, but I think across the board, this could be pretty huge.
• 32:32
  SPEAKER_01: It is.
• 32:32
  SPEAKER_01: And I spent I spend a lot of time in the book um translating this science so it's understandable to the average person.
• 32:39
  SPEAKER_01: And so I talk a lot about AMPK and MTOR.
• 32:42
  SPEAKER_01: And so those things sit at the opposite end of this of the seesaw.
• 32:45
  SPEAKER_01: And of course, you need mTOR because it's anabolic, but you also need to have AMK activated.
• 32:50
  SPEAKER_01: And we know now that if you can really inhibit mTOR to a great deal, but not to the point where it becomes pathologic, um, you change everything in the body.
• 32:58
  SPEAKER_01: And so so here's this this seesaw.
• 33:01
  SPEAKER_01: AMPK, when it goes up, inflammation goes down.
• 33:04
  SPEAKER_01: MTOR, anabolic, when that goes up, so does inflammation to a certain extent, but we have to have a balance.
• 33:10
  SPEAKER_01: We need to have mTOR.
• 33:11
  SPEAKER_01: But any drug that's going to come up that's gonna control mTOR is gonna be a life extender, I'd say, by decades.
• 33:19
  SPEAKER_01: And so we're I think we're almost there, and there's some things happening, uh, but they're still in early stages.
• 33:24
  SPEAKER_01: But if you just go ahead and you go ahead and follow the book, and if you if you do need to lose some weight and you get your under a physician's care and you start on uh terzapatite, something like that, uh, you're gonna notice a huge difference too, it accelerates that.
• 33:40
  SPEAKER_01: But the point is it all comes down to metabolism.
• 33:42
  SPEAKER_01: You can press that button uh with lifestyle, moderate exercise, anti-inflammatory diet in in ways that are natural and inexpensive.
• 33:50
  SPEAKER_01: Hydrogen water, amazing.
• 33:51
  SPEAKER_01: Anti-inflammatory, upregulates AMK, suppresses mTOR, and uh has, and because of its size, it gets in the body, central nervous system instantly.
• 34:00
  SPEAKER_01: Twice a day, it should be done every day, helps normalize your metabolism.
• 34:04
  SPEAKER_01: In fact, in Japan, they actually have hydrogen water for the pets because the life extension on pets is amazing, uh, having hydrogen water.
• 34:11
  SPEAKER_01: And but it's all anti-inflammatory.
• 34:13
  SPEAKER_01: So that was the magic bullet.
• 34:14
  SPEAKER_01: I found it.
• 34:15
  SPEAKER_01: I was very skeptical.
• 34:16
  SPEAKER_01: Uh I didn't think it was possible, but it it does work.
• 34:19
  SPEAKER_01: And so my it's getting out there.
• 34:21
  SPEAKER_01: We're right now uh manufacturing thousands and thousands of cases of hydrogen for the release of this.
• 34:27
  SPEAKER_01: And it has to be therapeutic levels, it has to be stable.
• 34:31
  SPEAKER_01: I checked a lot of the people with hydrogen waters on the shelves, you take them out.
• 34:35
  SPEAKER_01: Uh they're subtherapeutic after a couple months, they have the wrong packaging.
• 34:39
  SPEAKER_01: And we have six and a half years of stability.
• 34:41
  SPEAKER_01: So I want to make sure they get the right thing.
• 34:43
  SPEAKER_00: That is so exciting.
• 34:44
  SPEAKER_00: Wow.
• 34:44
  SPEAKER_00: I mean, what a breakthrough.
• 34:45
  SPEAKER_00: I mean, at the end of the day, I I always wonder, you know, do you think that this is going to be something?
• 34:52
  SPEAKER_00: Well, I hope it is, adapted into like, you know, the medical world easily.
• 34:56
  SPEAKER_00: Because I would love to see start seeing patients, you know, being given this option and being told, like, listen, there is a way for you to combat a lot of the issues you're dealing with.
• 35:05
  SPEAKER_00: You know, go you can drink hydrogen water, it has real you know, impact.
• 35:09
  SPEAKER_00: What are your thoughts around that with this whole translation of, you know, discovering this and then bringing this to like the mass medical fields?
• 35:17
  SPEAKER_01: Yeah, so it's been my experience, unfortunately, that the change is going to come from the population, not from the medical people.
• 35:24
  SPEAKER_00: Yeah.
• 35:25
  SPEAKER_01: And so when I wrote my first book on inflammation, aging disease, and this and uh the uh publisher changed it to what I thought was trivializing the contents, but I still sold millions of books.
• 35:34
  SPEAKER_01: It was called a wrinkle cure.
• 35:36
  SPEAKER_01: And I talked about metabolism and anti-inflammatory diet.
• 35:39
  SPEAKER_01: So then once that came, then the um scientists and medical community had to look at this.
• 35:46
  SPEAKER_01: And that's why it's mainstream now, because they did look and they said, okay, wow, but if you could just see the animosity of 20, 25 years ago, I don't want to get into it.
• 35:55
  SPEAKER_01: It's just just uh very unexpected, it's just a very unpleasant time uh to do this.
• 36:00
  SPEAKER_01: And um and I'm interested right now in science in general, and I've always been interested in physics because I feel a lot of these therapeutics can come from physics by using certain frequencies.
• 36:09
  SPEAKER_01: I think that's the future of medicine.
• 36:11
  SPEAKER_01: But um, I sent a paper into a prestigious physics journal um about some of the work I'm doing.
• 36:18
  SPEAKER_01: And um now this is um, I said it's very prestigious, and this went to the um senior editor, and it was rejected, of course, because it's all new.
• 36:26
  SPEAKER_01: And um, so I I he sent um I sent him an email first.
• 36:30
  SPEAKER_01: So I thanked him for getting to me right so right away so I can then get this to another journal.
• 36:34
  SPEAKER_01: But then I asked you if you have any comments on my paper, which might be helpful.
• 36:39
  SPEAKER_01: So uh they're talking about we're talking about a scientist, senior editor, been there forever, physicist, obviously high IQ.
• 36:46
  SPEAKER_01: This is what he responded.
• 36:48
  SPEAKER_01: The title offended me, the content offended me, and you offend me.
• 36:53
  SPEAKER_00: Oh my god.
• 36:54
  SPEAKER_01: Yes.
• 36:55
  SPEAKER_00: Oh my god.
• 36:55
  SPEAKER_01: Yes.
• 36:57
  SPEAKER_01: Wow.
• 36:58
  SPEAKER_01: Now, all the others I sent in, they still get rejected, but they're polite.
• 37:01
  SPEAKER_01: But this is the great way to start.
• 37:02
  SPEAKER_01: And that was that was just such an example of what I've been through in the past.
• 37:06
  SPEAKER_01: And um, and all we're trying to do is we're we're trying to move forward with science.
• 37:10
  SPEAKER_01: Because look, science is everything.
• 37:12
  SPEAKER_01: You know, science is going to change this world.
• 37:14
  SPEAKER_01: We've got to, we've got to rescue our environment, we've got to teach people how to take care of themselves, um, and we have to have, and we want to have long, healthy lives that are productive.
• 37:24
  SPEAKER_01: And so my theory and and what actually my philosophy is this everybody on this planet has a mission.
• 37:30
  SPEAKER_01: I don't care what you're doing, if you think it's trivial, it's not trivial.
• 37:33
  SPEAKER_01: Whatever you're doing is a mission, and we need this.
• 37:36
  SPEAKER_01: We're part of society.
• 37:36
  SPEAKER_01: We're just gears in this huge, huge, massive amount of people.
• 37:41
  SPEAKER_01: And so to so, and you know when you're on your mission because you feel it every day.
• 37:45
  SPEAKER_01: And so to implement that mission, you have to have a sound body and you have to have a sound mind.
• 37:49
  SPEAKER_01: So you've got to be healthy to do this.
• 37:51
  SPEAKER_01: So this is so important to you on an individual.
• 37:54
  SPEAKER_01: And I talk to people all the time, and they say, gee, you know, you're so accomplished, and I think, and they tell me what they do, and they feel for some reason they feel like what they're doing is not enough.
• 38:02
  SPEAKER_01: Everybody has a spot here, and this is critical, just as critical as the work you and I are doing.
• 38:07
  SPEAKER_01: So let's let's get everybody at this realize your mission.
• 38:11
  SPEAKER_01: Once you realize your mission, things change.
• 38:14
  SPEAKER_01: And it changes the way you approach things.
• 38:16
  SPEAKER_01: So all I'm here for to do is look, I want to make sure that you have a body and a mind that's gonna help you implement your mission.
• 38:22
  SPEAKER_01: And I, you know, human suffering is going on all the time.
• 38:25
  SPEAKER_01: And then you have naysayers in the medical community, in the scientific community, it delays things for decades.
• 38:30
  SPEAKER_01: And so, how many people have we lost, you know, over the decades while we're waiting for people to catch up?
• 38:35
  SPEAKER_01: So that's what's uh bothering me.
• 38:38
  SPEAKER_01: As far as the physics community goes, they're at a dead end, they know they're at a dead end, they don't know what they're doing.
• 38:43
  SPEAKER_01: Um, they have they have the particle zoo, there's 25 particles, and and there's just evidence against that.
• 38:50
  SPEAKER_01: It doesn't, there are no particles, everything is energy.
• 38:53
  SPEAKER_01: And so and they have so much proof, and they send these in day after day, and you know, all the data, and and and I'm not a mathematician, but now, you know, with with the help of artificial intelligence, the math can be done for you.
• 39:05
  SPEAKER_01: Uh, and so you're just a theoretical physicist.
• 39:08
  SPEAKER_01: And anybody could be.
• 39:08
  SPEAKER_01: By the way, Einstein had was not a mathematician.
• 39:11
  SPEAKER_01: His wife was brilliant, she was Lithuanian.
• 39:13
  SPEAKER_00: Yes, exactly.
• 39:14
  SPEAKER_00: Yeah, I know people always credit, uh I I know they always give him credit, but that's the biggest thing about physics.
• 39:20
  SPEAKER_00: You know, I think that at the end of the day, one of the biggest things I'm seeing um in that, specifically in that discipline, is that no one's talking about biophysics.
• 39:28
  SPEAKER_00: I mean, everything you've spoken to me about today, I have a master's in uh medical physiology and biophysics, and for me, biophysics is the understanding of how exactly these molecules are going and altering our machinery, you know, and enhancing it.
• 39:42
  SPEAKER_00: And I think that if we started looking at things from that lens more and start speaking about the topics that you've you touched on here today, we would be in a totally different place now, you know, when it comes to not only our individual health or our healthcare system, the way that we approach science, the way we analyze science.
• 39:58
  SPEAKER_00: I mean, at the end of the day, yeah, you can talk about, you know, like you said, particles and all of this stuff all day long.
• 40:05
  SPEAKER_00: But if you don't translate that into something that's meaningful and it's actually propelling science in a forward direction, right?
• 40:11
  SPEAKER_00: I mean, there's absolutely no use for it.
• 40:13
  SPEAKER_00: So, you know, I really do, I'm also perplexed, you know, in in my own way when I look at how the scientific community approaches solution-oriented, you know, research.
• 40:25
  SPEAKER_00: It's very, very hard now to get a paper published where, you know, even if you have, you might not have every single piece of data yet, but you're still putting out these concepts.
• 40:35
  SPEAKER_00: I mean, if you can have theoretical physics, why can't you have theoretical genetics, theoretical epigenetics, theoretical longevity science?
• 40:42
  SPEAKER_00: Why can't we do that?
• 40:43
  SPEAKER_00: I mean, they get equal, you know what I mean?
• 40:45
  SPEAKER_00: They get so much respect in the physics world for theoretical physics.
• 40:49
  SPEAKER_00: You know, let's do that in biology and physiology.
• 40:51
  SPEAKER_00: You know, I'd love to see that.
• 40:52
  SPEAKER_00: So, I mean, I'm with you, I think, uh, in that way very much.
• 40:57
  SPEAKER_01: Yeah, I think you're so right on.
• 40:58
  SPEAKER_01: And I have a suspicion that um uh good mathematicians don't make very good uh uh theoretical physicists, except for Niels Bohr.
• 41:06
  SPEAKER_01: Niels Bohr was the one who elucidated the hydrogen uh atom.
• 41:10
  SPEAKER_01: Uh he was one of those uh uh, I guess, unicorns uh that was a great mathematician and also a great theoretical physicist.
• 41:17
  SPEAKER_01: So um if we can get away from math, in fact, there's this uh physicist, uh her name is uh Sabina Hossenfelder.
• 41:24
  SPEAKER_01: She just wrote a book called Lost in Math.
• 41:26
  SPEAKER_01: It's fantastic.
• 41:27
  SPEAKER_01: I love that.
• 41:28
  SPEAKER_01: And then you know Michael Faraday said that math obscures reality.
• 41:32
  SPEAKER_01: Well, we're not gonna worry about me obscuring it.
• 41:34
  SPEAKER_01: Don't know much math, but I sure know I'm a pretty good theorist.
• 41:37
  SPEAKER_00: Yeah, no, I mean I I I love what you're doing, and I love that you're putting this, you know, science out there.
• 41:43
  SPEAKER_00: This is so fascinating to me.
• 41:44
  SPEAKER_00: And uh, you know, for everyone listening, I really encourage you guys, you gotta read the book.
• 41:49
  SPEAKER_00: Um, it's called The Beauty Molecule, um, and really, you know, kind of try to understand that the when it comes to aging, you know, everything Dr.
• 41:57
  SPEAKER_00: Peregrine has spoken about today, there's this is a very complex thing that we're looking at in the sense of, you know, you have to look at it from a different way.
• 42:06
  SPEAKER_00: You know, it can't just be about I'm putting this on my skin, and that's going to slow down all of my concerns when it comes to wrinkles or it has to be very systemic, it has to be very integrated medicine, if you, you know, for lack of a better term, I guess.
• 42:20
  SPEAKER_00: Um, but Dr.
• 42:20
  SPEAKER_00: Peregrine, I'd love for you to share if there is one message that you hope people take away from the beauty molecule, what do you hope that is?
• 42:27
  SPEAKER_01: Well, you're gonna find out that um everything is uh fairly simple.
• 42:31
  SPEAKER_01: Um, nature is simple, and uh it was um made by a brilliant scientist.
• 42:36
  SPEAKER_01: Um, some people call it God, some people call it the universe, you call it whatever you want.
• 42:40
  SPEAKER_01: Um, but it's simple.
• 42:42
  SPEAKER_01: And uh if you follow these things, uh anti-inflammatory diet, moderate exercise, get some rest, and uh try to do things that elevate the um beauty molecule, acetylcholine.
• 42:52
  SPEAKER_01: So, and so all of these strategies I put in there are life changers.
• 42:56
  SPEAKER_01: And you don't have to do anything radical at all.
• 42:59
  SPEAKER_01: And just remember that you're on a mission.
• 43:01
  SPEAKER_01: Once you think about that, and you'll know what your mission is.
• 43:03
  SPEAKER_01: We all know what it is.
• 43:04
  SPEAKER_01: And you go ahead and you follow that.
• 43:06
  SPEAKER_01: It's gonna change your life in a real positive way.
• 43:08
  SPEAKER_01: Just follow this road.
• 43:09
  SPEAKER_00: Thank you so much, Dr.
• 43:10
  SPEAKER_00: Perikarner.
• 43:11
  SPEAKER_00: It has been such an honor to host you.
• 43:12
  SPEAKER_00: And I'm so, so excited that you wrote this book and the wonderful research you're doing.
• 43:17
  SPEAKER_00: It's it's so meaningful.
• 43:18
  SPEAKER_00: So thank you for pushing ahead and pushing science and the boundaries of our understanding.
• 43:23
  SPEAKER_00: It it's, I mean, truly it's amazing to see someone do that, especially in today's landscape and the way that academia is, you know.
• 43:30
  SPEAKER_00: Um, it's kind of become a big game these days, from what I've seen, you know, in just my short time in medicine.
• 43:36
  SPEAKER_00: And it's just so refreshing to see somebody who's really out here and trying to discover what is the next thing, you know, what what is that simplicity that ties everything together?
• 43:46
  SPEAKER_00: It's it's a beautiful thing to see.
• 43:48
  SPEAKER_00: So thank you for your work.
• 43:49
  SPEAKER_01: Well, thank you for contacting me.
• 43:51
  SPEAKER_01: It's great to know you and uh know that you're uh one of us, and we we've got this um uh huge uh mountain ahead of us, and it's all based on education uh of the right kind.
• 44:01
  SPEAKER_01: And unfortunately, uh the higher up you go in in the um in the academic uh area, the more difficult it gets.
• 44:08
  SPEAKER_01: Uh so um the we have to change that so we have the the leaders uh on on all levels, not just on one level.
• 44:16
  SPEAKER_01: So welcome to the team and please stay in please please stay in touch with me.
• 44:20
  SPEAKER_00: Thank you.
• 44:21
  SPEAKER_00: Yes, sir.
• 44:21
  SPEAKER_00: I I definitely will.
• 44:22
  SPEAKER_00: Thank you so much for your time.
• 44:24
  SPEAKER_00: This has been such a it's very surreal for me, you know.
• 44:27
  SPEAKER_00: I'm I've been such a fan of yours for so long.
• 44:29
  SPEAKER_00: So thank you for the opportunity and for everyone tuning in.
• 44:32
  SPEAKER_00: I I hope you will chime in with your thoughts, you know, after you read the book.
• 44:35
  SPEAKER_00: Let us know what you think, and I'd love to hear from you.
• 44:37
  SPEAKER_00: Thank you so much.
• 44:38
  SPEAKER_00: Hey guys, so I hope you love that episode.
• 44:41
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• 44:46
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• 45:29
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• 45:34
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• 45:45
  SPEAKER_00: Thank you.