943-The Mouse Brain Atlas of Dendritic Microenvironments

Paper Talk · May 10, 2026 · 19m

This research introduces CCF-ME, a high-resolution mouse brain atlas developed by analyzing the dendritic microenvironments of over 100,000 neurons. Unlike traditional maps based on cell density, this framework groups neurons by integrating the morphological features of their local neighborhoods to reveal a more detailed anatomical organization. This innovative approach nearly doubles the number of identifiable brain regions, providing a finer-grained view than the standard Allen Common Coordinate Framework. The study demonstrates that these local structural patterns are highly predictive of…