Latest / Go UnPro: A Doctor’s 52 Week Journey to an Unprocessed Life
Sunday Science Week 3 Klotho Gene and Enzyme
The Go UnPro Podcast Sunday Science Week 3 Klotho Gene And Enzyme
Speaker-Organized Summary: Key Points, Decisions, and Next Steps
Dr. Brent Laartz
Summary of Key Points and Decisions
The discussion focuses on a gene and gene product called Klotho, which was discovered in 1997 and is named after the Greek god of fate and destiny.
Knockout mice with Klotho upregulation showed a 15-30% longer lifespan and improved cardiovascular, renal, and brain health, as well as lower rates of cognitive decline.
However, a recent study published in the Journals of Gerontology in 2025 found a U-shaped…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.