1579-Genomic Architecture and Viral Adaptation in Bats
The paper details a comprehensive genomic study of Myotis bats, a genus renowned for its exceptional longevity and viral tolerance. By assembling near-complete genomes for eight species, researchers identified unique genetic adaptations that differentiate bats from other mammals, particularly in how they interact with DNA and RNA viruses. The study highlights a significant copy-number polymorphism in the immune factor PKR, suggesting a balanced evolutionary trade-off between antiviral defense and cellular toxicity. Furthermore, the findings link the evolution of long lifespans to enhanced…
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