The Brain’s Redox Crisis: NAD, Mitochondria, and the Next Wave of Neuropsychiatric Treatment
What if some of the hardest brain disorders aren’t just “neurotransmitter problems” or “protein problems,” but redox problems — where the NAD⁺/NADH balance drifts, mitochondrial performance declines, oxidative stress rises, and inflammation becomes self-reinforcing? In this Deep Dive, Dr. Mike breaks down a review arguing that bioenergetic failure may be a shared organizing principle across neurodegenerative disease (Alzheimer’s, Parkinson’s, ALS) andpsychiatric illness (schizophrenia, bipolar disorder). We cover why raising NAD in blood isn’t the same as fixing compartmentalized brain redox…
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