Week 11 College Football Picks for the 10 Biggest Games! 2025

Winning Cures Everything | College Football · Nov 4, 2025 · 1h 6m

Week 11’s 10 Biggest Games are loaded with edges—and we’ve got picks backed by pace, success rate, PPA margin, and finishing-drives data you can actually use before kickoff. We start at Kinnick with Oregon vs Iowa (elite trench chess match), roll into LSU at Alabama (Tide passing efficiency vs LSU’s road form), and hit BYU at Texas Tech with College GameDay in Lubbock (BYU’s TO/ST edge vs Tech’s grind).We keep it moving: Indiana at Penn State (Hoosiers’ 2H dominance), Texas A&M at Missouri (freshman QB vs Elko defense), Navy at Notre Dame (Irish roll, number too big), Auburn at Vanderbilt…