Latest / The Trauma Therapist / Guest Host: Christina P. Kantzavelos interviews Rick Doblin, Ph.D
Transcript
- 0:00Speaker 1: Welcome to the Trauma Hippis Podcast. My name is gommickperson
- 0:04Speaker 1: I interview incredible people who dedicated their lives to helping
- 0:07Speaker 1: those who have been impacted by trauma.
- 0:09Speaker 2: Here we go, Hey Rik, nice to see you.
- 0:14Speaker 1: Oh well, great, great to be here.
- 0:16Speaker 2: Thank you, Thank you so much. So we're going to start.
- 0:20Speaker 3: We're going to get into it and start with the basics,
- 0:22Speaker 3: which is what is NDMA and from your perspective, why
- 0:28Speaker 3: is it such a powerful healing tool.
- 0:30Speaker 1: Well, let me start by saying that MDMA is not
- 0:33Speaker 1: a plant medicine, which MDMA is a synthetic chemical. As
- 0:41Speaker 1: far as we know, it does not appear in nature.
- 0:44Speaker 1: It was invented by Merk in nineteen twelve, the pharmaceutical company.
- 0:49Speaker 1: They found nothing interesting in it in all of their
- 0:52Speaker 1: animal studies, so they never did anything in humans. MDMA
- 0:56Speaker 1: is more widely known as ecstasy, and it was a
- 1:01Speaker 1: therapy drug from the middle seventies to the early eighties
- 1:04Speaker 1: before it became the party drug ecstasy, and that's what
- 1:08Speaker 1: ended up causing it to be criminalized in nineteen eighty five.
- 1:12Speaker 1: But what it does is it helps people to approach
- 1:18Speaker 1: difficult conversations, difficult emotional traumatic memories in a less fear
- 1:24Speaker 1: based manner. It has oxytocin, which is the hormone of
- 1:29Speaker 1: love and connection that it releases, so people feel more empathic,
- 1:33Speaker 1: both to others and to themselves. It has a lot
- 1:36Speaker 1: to do with self compassion, and it has properties that
- 1:42Speaker 1: can be very useful in a therapeutic context when people
- 1:46Speaker 1: are facing frightening memories that are overwhelming. It sort of
- 1:52Speaker 1: calms the fear centers of the brain, the amigla, so
- 1:56Speaker 1: that people can experience and express what's happened in the
- 2:02Speaker 1: past that has previously felt overwhelming.
- 2:05Speaker 3: Okay, great, and so for those who you know, even myself,
- 2:09Speaker 3: right we hear sasafras it being the derivative of sasafras,
- 2:13Speaker 3: It doesn't have to do with that, correct when people
- 2:15Speaker 3: think of it.
- 2:17Speaker 1: Well, you can get from sassafras, you get saffral oil,
- 2:20Speaker 1: and then you modify it a bunch of times and
- 2:23Speaker 1: then you can get MDMA. People have a romantic attachment
- 2:28Speaker 1: to plant medicines, so you know, market it's good marketing
- 2:32Speaker 1: to call it sasafras, but it's not in sasafras.
- 2:36Speaker 2: Fair enough.
- 2:36Speaker 3: Thank you for clarifying that, because I know some people
- 2:38Speaker 3: say about there, like it's technically a plant medicine. I'm like, no,
- 2:42Speaker 3: not exactly, not exactly. So in terms of your you know,
- 2:47Speaker 3: the research you've been a part of, and what you've
- 2:50Speaker 3: seen in long term healing, especially with like treatment resistant PTSD,
- 2:55Speaker 3: I mean, what can you tell us about what has
- 2:57Speaker 3: come out of the clinical trials and everything.
- 3:01Speaker 1: Well, MAPS has been doing research. MAPS meaning you know,
- 3:05Speaker 1: Multidisplinary Association for Psychedelic Studies are nonprofit which I started
- 3:09Speaker 1: in eighty six, and also our sort of public benefit
- 3:13Speaker 1: pharma company that is now not ours but most owned
- 3:17Speaker 1: by investors. We began work with PTSD in two thousand,
- 3:23Speaker 1: so there's been basically twenty five years of research with
- 3:26Speaker 1: MDMA assisted therapy for post traumatic stress disorder. And I
- 3:31Speaker 1: want to make the first point that it's really therapy
- 3:33Speaker 1: more than the drug that loads and loads of people
- 3:37Speaker 1: twenty million Americans have taken MDMA or ecstasy, and a
- 3:42Speaker 1: lot of them had PTSD and still at PTSD or
- 3:45Speaker 1: had some other issues. So what we really think about
- 3:48Speaker 1: as the operating principle is the therapeutic relationship, this safe
- 3:52Speaker 1: support of trusting relationship called a therapeutic alliance that can
- 3:57Speaker 1: be built between a patient and the therapist, and then
- 4:01Speaker 1: within that the MDMA makes it easier for these traumas
- 4:05Speaker 1: to surface and then to be processed.
- 4:11Speaker 2: That's incredible.
- 4:12Speaker 3: And what what have the results been from what you
- 4:15Speaker 3: guys have researched.
- 4:17Speaker 1: Yeah, so there's basically from two thousand to twenty sixteen,
- 4:23Speaker 1: we did what are called phase two studies, and that's
- 4:25Speaker 1: where you look at what the doses are used, what's
- 4:28Speaker 1: your patient population, what are your outcome measures, what's your
- 4:32Speaker 1: therapeutic intervention, and so from that, what we learned is
- 4:37Speaker 1: that the healing potential of MDMA systic therapy is independent
- 4:42Speaker 1: of the cause of the trauma. So if somebody had
- 4:46Speaker 1: sexual abuse or you know, violent attack or war related
- 4:50Speaker 1: or fires from the you know PTSD from the fires
- 4:54Speaker 1: in LA or other things that once you have PTSD,
- 5:01Speaker 1: it's sort of this repetitive, fear based emotions that never
- 5:07Speaker 1: never really go away. The emotion is that the experiences
- 5:10Speaker 1: are never really processed. So once you start to phase
- 5:15Speaker 1: three studies, what we found is that we compared therapy
- 5:20Speaker 1: with no MDMA versus therapy with MDMA, and so we
- 5:25Speaker 1: have three eight hour sessions one month apart, and then
- 5:31Speaker 1: twelve ninety minute non drug psychotherapy sessions, three for preparation
- 5:35Speaker 1: before the first MDMA session and then three for integration
- 5:40Speaker 1: after each MDMA or therapy without any MDMA session, So
- 5:43Speaker 1: it's the same forty two hours of therapy whether you
- 5:47Speaker 1: get therapy with no MDMA or therapy with MDMA. So
- 5:50Speaker 1: the first study was severe PTSD, and what we showed
- 5:54Speaker 1: is that thirty two percent of the people that got
- 5:56Speaker 1: therapy without any MDMA at all no longer had BED
- 6:01Speaker 1: at the two month follow up, which is really pretty good.
- 6:04Speaker 1: We had a very low dropout rate. However, when you
- 6:07Speaker 1: add MDMA, more than doubles to the sixty seven percent,
- 6:12Speaker 1: so that's pretty remarkable. And another twenty one percent had
- 6:16Speaker 1: what's called clinically significant reductions of PTSD symptoms, meaning that
- 6:21Speaker 1: they still have PTSD but their symptoms have declined enough
- 6:24Speaker 1: that it's a noticeable difference in their lives. So those
- 6:27Speaker 1: are called responders. So we had eighty eight percent responders
- 6:30Speaker 1: and twelve percent where it just didn't work. Then the
- 6:35Speaker 1: second study was we expanded it to moderate to severe PTSD,
- 6:41Speaker 1: but three quarters of them had severe PTSD, around one
- 6:44Speaker 1: quarter had moderate PTSD. And keep in mind, now these
- 6:48Speaker 1: are the therapists we had sites in Israel, Canada, in
- 6:51Speaker 1: the US. They've had practice. Now they're working in this context.
- 6:54Speaker 1: They're getting better and better. So in the second study,
- 6:57Speaker 1: forty seven percent no longer had PTSD from the therapy
- 7:02Speaker 1: without any MDMA at all, which is better than any
- 7:06Speaker 1: other therapy for PTSD, with very very low dropout rate. Also,
- 7:13Speaker 1: so studies that were done by the Veterans Administration took
- 7:16Speaker 1: them around six years, nine hundred and fourteen veterans comparing
- 7:20Speaker 1: cognitive processing therapy versus prolonged exposure. About fifty percent of
- 7:25Speaker 1: the people dropped out of the study because the therapy
- 7:28Speaker 1: was retraumatizing. They had to go over their therapy, their
- 7:32Speaker 1: trauma over and over and over. But it just didn't
- 7:35Speaker 1: have the reductions of fear, that sense of self acceptance
- 7:39Speaker 1: that comes from the MDMA. So we had very low
- 7:42Speaker 1: dropout rate and credible forty seven point six percent no
- 7:46Speaker 1: longer had PTSD. But when you add MDMA, now it's
- 7:51Speaker 1: about seventy two percent no longer had PTSD and another
- 7:56Speaker 1: fifteen percent had clinically significant reductions of PtD. So according
- 8:01Speaker 1: to Besilvanderkoch, who wrote the book The Body Keeps the Score,
- 8:04Speaker 1: which many people have probably heard about about trauma and
- 8:08Speaker 1: all the different treatments. He's published a paper recently that's
- 8:11Speaker 1: saying that he thinks this is the most effective approach
- 8:14Speaker 1: to treating PTSD is therapy combined with MDMA.
- 8:20Speaker 3: Wow, that is so incredible to see those numbers laid out.
- 8:25Speaker 3: And you know, my other question was, like, so many
- 8:29Speaker 3: therapists hit a wall in traditional talk therapy, and especially
- 8:32Speaker 3: when it comes to complex trauma, and so like, how
- 8:36Speaker 3: do you see therapists, Like what role do you see
- 8:39Speaker 3: therapists playing in this new frontier with this?
- 8:42Speaker 1: Well, well, again, it's not the drug, it's the therapists.
- 8:45Speaker 1: It's the therapeutic relationship. So therapists are going to be
- 8:48Speaker 1: key to going forward. You know, according to the Veterans Administration,
- 8:53Speaker 1: not just among veterans, but there's thirteen million PTSD patients
- 8:57Speaker 1: in America alone, hundred and hundreds and hundreds of millions
- 9:01Speaker 1: of PTSD patients all over the world, and so therapists
- 9:05Speaker 1: are going to be key. However, when we talk about
- 9:08Speaker 1: for example, Rwanda or South Africa or Ukraine for example,
- 9:15Speaker 1: you know, war zones things that there's enormous amount of trauma.
- 9:18Speaker 1: There's not very many psychiatrists and therapists in these places.
- 9:23Speaker 1: So I think we're going to be expanding to looking
- 9:26Speaker 1: at nurses, to looking at other kinds of healers in
- 9:29Speaker 1: other places. But it's always going to be the case
- 9:32Speaker 1: that the context that is created by therapists or nurses
- 9:39Speaker 1: or even friends peer support. We do a lot of
- 9:43Speaker 1: work on peer support that they're going to be absolutely
- 9:47Speaker 1: essential because it's not. It's fundamentally different than the drugs
- 9:52Speaker 1: you get from your psychiatrists, which are meant to control
- 9:55Speaker 1: the symptoms, and you just take them on your own
- 9:57Speaker 1: at home on a daily basis. This is you take
- 10:01Speaker 1: them only a few times, the MDMA only a few
- 10:03Speaker 1: times with the therapist there the whole time during an
- 10:06Speaker 1: eight hour therapy session, and you go to the root
- 10:09Speaker 1: causes and try to reprocess. And then there's a whole
- 10:13Speaker 1: other new area of neurosciences called neuroplasticity. So what it
- 10:18Speaker 1: means is that psychedelics can open up what are called
- 10:22Speaker 1: critical periods where you can re format your brain in
- 10:28Speaker 1: a way, you process information in a different way, and
- 10:32Speaker 1: that's where the integration part comes in where you sort
- 10:34Speaker 1: of reinforce what happened during this session with the MDMA
- 10:39Speaker 1: and then you can reinforce it. So I think, as
- 10:42Speaker 1: we want to really scale this to address the enormous
- 10:46Speaker 1: trauma that exists in our world, there's also what's called
- 10:49Speaker 1: epigenetic trauma. So what that means is multi generational trauma.
- 10:54Speaker 1: There's been research that shows that trauma can be passed
- 10:59Speaker 1: down through the generations, so it's more like a set
- 11:02Speaker 1: point for anxiety or depression or things or fear. And
- 11:08Speaker 1: there's research that Rachel Judah has done at the bronx
- 11:11Speaker 1: DA with people who have received mdmasist at therapy, and
- 11:16Speaker 1: she's looked at the epigenetics before and after therapy, and
- 11:19Speaker 1: there's preliminary suggestions that successful therapy, and it doesn't necessarily
- 11:24Speaker 1: need to be through MDMA, but successful therapy can change
- 11:28Speaker 1: these epigenetic mechanisms so that we don't need to keep
- 11:32Speaker 1: passing this trauma down the generational line.
- 11:37Speaker 3: That is amazing, and you know they say it's seven
- 11:40Speaker 3: to fourteen generations back seven to generations or seven to
- 11:43Speaker 3: fourteen generations boards, so we can really shift the way
- 11:47Speaker 3: our genes are expressed right from day to day and disease,
- 11:52Speaker 3: and really people don't realize that it's only ten to
- 11:55Speaker 3: twenty percent of the role that our DNA plays in disease.
- 12:00Speaker 3: So epigenetics are huge and he so much. So that's
- 12:05Speaker 3: that's fantastic. And you know, sometimes when i'm you know,
- 12:10Speaker 3: speaking with a client who's interested in sitting with you know,
- 12:13Speaker 3: MDMA or any psychedelic but we're discussing MDA specifically, they
- 12:17Speaker 3: worry about perhaps losing control or being retraumatized. How is
- 12:22Speaker 3: this addressed in preparation?
- 12:26Speaker 1: Well, the first part about being re traumatized, that's what
- 12:31Speaker 1: I talked about in terms of the research that was
- 12:34Speaker 1: done with prolonged exposure and cognitive processing therapy. If you're
- 12:38Speaker 1: being asked to just go over and over and over
- 12:40Speaker 1: the trauma without even if you have a good therapeutic relationship,
- 12:46Speaker 1: that can be re traumatizing because it's been overwhelming before.
- 12:50Speaker 1: So the thing that addresses the re traumatization part is
- 12:55Speaker 1: this eight hour session because we are not asking people
- 13:00Speaker 1: to go to their trauma. We're saying to people, whatever
- 13:04Speaker 1: you're concerned about, whatever happens, whatever emerges, you can deal
- 13:08Speaker 1: with it in whatever time frame you want, so we
- 13:11Speaker 1: support what's emerging. We're not trying to move people to
- 13:15Speaker 1: the trauma. So I think when people have to engage
- 13:18Speaker 1: with the trauma too quickly, that can be retraumatizing. The
- 13:22Speaker 1: other part that makes it so that it's not so
- 13:26Speaker 1: retraumatizing is the MDMA itself, is that it reduces this
- 13:30Speaker 1: fear response so that these emotions and these memories can
- 13:34Speaker 1: be processed. And actually people remember more of the trauma
- 13:39Speaker 1: when they're under the influence of MDMA because parts of
- 13:42Speaker 1: it they've put out of their mind. And so we
- 13:44Speaker 1: have many many stories and people that are under MDMA
- 13:47Speaker 1: therapy and they've said, oh, I'm here because I was
- 13:51Speaker 1: in a war and this is my trauma. And then
- 13:53Speaker 1: you work through that, and then they start talking about
- 13:56Speaker 1: how when they were children they had an abusive father
- 13:59Speaker 1: and we're beaten up. And so a lot of times
- 14:02Speaker 1: people have put certain traumas out of their mind, and
- 14:05Speaker 1: so that MDMA can really help them process it in
- 14:09Speaker 1: a way so that it's not retraumatizing. The first part
- 14:14Speaker 1: of your question, though, was not about re traumatizing. It
- 14:16Speaker 1: was about the role the.
- 14:21Speaker 3: What was I saying, the role of what therapists, that
- 14:24Speaker 3: therapists will play in this.
- 14:26Speaker 1: Oh yeah, but it was after that, I'm sorry, it was.
- 14:31Speaker 2: Oh, preparation, how do we How is this addressed in preparation?
- 14:35Speaker 1: Yeah? Okay, So the key parts of the preparation and
- 14:40Speaker 1: usually in the experiment at least we would have three
- 14:42Speaker 1: ninety minute sessions roughly once a week. So the preparation
- 14:47Speaker 1: is to help people understand what MDMA does, to help
- 14:52Speaker 1: them understand that there's a basis of sort of basic
- 14:57Speaker 1: information about what their trauma was, what the issues might
- 14:59Speaker 1: come up. But it's more really about getting a feel
- 15:04Speaker 1: for whether the therapists and the patients are a good mex.
- 15:09Speaker 1: So occasionally in this preparation phase, for whatever reasons, either
- 15:14Speaker 1: the patient or the therapist will feel like they're not
- 15:16Speaker 1: a good match, and then they will find other therapists.
- 15:20Speaker 1: But the preparation is really very important about helping people
- 15:25Speaker 1: to feel that they are safe and supported. Oh also
- 15:30Speaker 1: losing control, That was what you think, Okay, So that
- 15:34Speaker 1: was the key part. So the preparation is to point
- 15:39Speaker 1: out that often the control is the problem because when
- 15:46Speaker 1: you keep things in control, but the fear is that
- 15:48Speaker 1: you get re traumatized. So it's to say that what
- 15:53Speaker 1: we like to say is that difficult is not the
- 15:55Speaker 1: same as bad. What's the difference between a difficult experience
- 16:00Speaker 1: in a bad experience as usually resistance or control, it's
- 16:04Speaker 1: keeping it in control. So both the drug and the therapeutic
- 16:08Speaker 1: alliance are there to try to help people feel that
- 16:13Speaker 1: there is this idea of losing control, but that you're
- 16:17Speaker 1: not out of control, but you're not suppressing feelings that
- 16:21Speaker 1: you think are overwhelming. Now you're able to process them.
- 16:25Speaker 1: So it's like you've built your capacity to have difficult
- 16:29Speaker 1: emotions flow through you. And so that's what the preparation
- 16:33Speaker 1: is for, so that the fear is that this is
- 16:36Speaker 1: a this is a safe place to quote lose control.
- 16:42Speaker 3: So by the time they actually sit with the medicine,
- 16:45Speaker 3: they feel resource, they feel like they're in a safe
- 16:48Speaker 3: enough container where if they quote unquote lose control, they're
- 16:53Speaker 3: with safe people to experience that. And generally speaking, it's
- 16:57Speaker 3: too therapists, right.
- 16:58Speaker 1: Yes, we often use male female. It's not always that way,
- 17:04Speaker 1: but yeah, there's two therapists because a lot of times
- 17:06Speaker 1: people who have PTSD have had childhood trauma and they
- 17:11Speaker 1: have like a well functioning male female team can be
- 17:14Speaker 1: really helpful. Again, we've sometimes to women to men, people
- 17:17Speaker 1: who don't identify with either gender in that way. But
- 17:23Speaker 1: we want it so that if one of the therapists
- 17:25Speaker 1: goes to the bathroom and somebody had this abandonment and
- 17:28Speaker 1: then they open their eyes and there's nobody there, that's
- 17:31Speaker 1: not so good. So we always want somebody to be there.
- 17:36Speaker 3: And for someone who hasn't sat with this medicine before,
- 17:41Speaker 3: eight hours probably seems like such a long time. For
- 17:43Speaker 3: those of us who have, it feels like it goes
- 17:46Speaker 3: it goes by like that.
- 17:47Speaker 2: Can you speak to that at all?
- 17:50Speaker 1: Yeah, Well, what we do is an initial dose. We
- 17:55Speaker 1: use the first MDMA session as eighty milligrams. The second
- 17:59Speaker 1: and third people can go up to one hundred and
- 18:01Speaker 1: twenty milligrams, but after two hours we add half the
- 18:04Speaker 1: initial amount, and that is precisely to make it longer,
- 18:08Speaker 1: to make the experience go longer. So again, this eight
- 18:12Speaker 1: hours is really protective. So if somebody feels like they're
- 18:15Speaker 1: approaching something and they feel like they're losing control. You know,
- 18:19Speaker 1: if you have an hour therapy session once a week
- 18:22Speaker 1: and you're thinking, oh, I got to make use of
- 18:24Speaker 1: all this time. But when you have an eight hour session,
- 18:27Speaker 1: you can approach something and you say I'm not ready
- 18:29Speaker 1: to deal with that, or I want to hold off
- 18:32Speaker 1: for a bit. You can do that and then you
- 18:34Speaker 1: come back around it at a later time. So it
- 18:38Speaker 1: has that kind of built in safeguard. And what people
- 18:42Speaker 1: feel is once it's like grief, you know, when people
- 18:45Speaker 1: are really someone that they love has died or something.
- 18:49Speaker 1: When you try to hold the grief in, you know,
- 18:52Speaker 1: it persists, but when you can cry and let it out,
- 18:57Speaker 1: you're processing the grief and then it moves from round
- 19:00Speaker 1: to background. So I think that's the way to say it. Now.
- 19:04Speaker 1: Actually I'll just tell one super fast story about one
- 19:07Speaker 1: of them.
- 19:07Speaker 2: Take your time, you know.
- 19:10Speaker 1: This was his first of three MDMA sessions, and what
- 19:13Speaker 1: he realized was under the influence of MDMA, he came
- 19:16Speaker 1: up with this insight that the PTSD was had something
- 19:21Speaker 1: good about it. It was the way that he showed
- 19:23Speaker 1: loyalty to their friends that had died. As long as
- 19:27Speaker 1: he was suffering, he had them in their mind, he
- 19:31Speaker 1: had them in his mind, I mean. And then what
- 19:34Speaker 1: he was able to do under the MDMA is see
- 19:38Speaker 1: himself from the eyes of his dead friends, and he
- 19:42Speaker 1: saw them saying to him, we cannot live. We don't
- 19:45Speaker 1: want you to honor us by being traumatized and not
- 19:49Speaker 1: able to do anything. You can honor us by living.
- 19:53Speaker 1: That would be better. And then he said, okay, what
- 19:57Speaker 1: am I going to do with the rest of my life?
- 20:00Speaker 1: And in that moment, he cured himself a PTSD because
- 20:03Speaker 1: he found a different way to honor his dead friends.
- 20:06Speaker 1: They could live through him rather than him suffering in
- 20:10Speaker 1: that way to show that he was connected to them.
- 20:12Speaker 1: And then he said, you know, I'm on opiates for pain,
- 20:16Speaker 1: but I don't really think I'm taking them for pain.
- 20:19Speaker 1: I don't need the opiates anymore. And then he said,
- 20:22Speaker 1: you know what, I don't even need the MDMA anymore.
- 20:24Speaker 1: I'm done. I want to drop out of the study.
- 20:27Speaker 1: And the researcher said, you can drop out anytime you want,
- 20:30Speaker 1: but would you do the two month and one year
- 20:32Speaker 1: follow up, which he did, and he did not have
- 20:35Speaker 1: PTSD at the two month, he didn't have it at
- 20:38Speaker 1: the one year, and that was about fifteen years ago
- 20:41Speaker 1: and he's still fine.
- 20:43Speaker 3: Oh, that's an incredible story. And you know I've said
- 20:48Speaker 3: this before, which is that grief. Feeling your grief won't
- 20:52Speaker 3: kill you. Not feeling it might because it festers.
- 20:55Speaker 1: Yes, that's exactly the point. That's exactly it.
- 20:58Speaker 3: It festers and ex our autonomic nervous system and our
- 21:01Speaker 3: immune system function, and our hormones.
- 21:04Speaker 2: And so much more.
- 21:05Speaker 3: And there's also I've noticed this this pattern sometimes where
- 21:10Speaker 3: you know, someone in our life has has passed away
- 21:13Speaker 3: and we have a lot of trauma around it, and
- 21:15Speaker 3: it's almost as though us suffering with that trauma is
- 21:18Speaker 3: how we stay connected to them. Yeah, like in this
- 21:23Speaker 3: in this case, and when in fact it's the other
- 21:25Speaker 3: way around. It's it's living in our joy, it's following
- 21:30Speaker 3: our joy, it's being in our joy and our healings.
- 21:32Speaker 3: So yes, thank you for that amazing story. That's that
- 21:37Speaker 3: tells you so much. And and I like what you said,
- 21:40Speaker 3: he healed himself like he healed his own pts. The
- 21:44Speaker 3: medicine just kind of you know, we say, the medicine
- 21:46Speaker 3: just kind of guides us to healing ourselves.
- 21:49Speaker 2: It doesn't it doesn't do it for us.
- 21:50Speaker 3: Of course, it sets things up in a really great
- 21:53Speaker 3: powerful way, especially with neuroplasticity and all of that.
- 21:55Speaker 2: But we do the work well.
- 21:57Speaker 1: And that's also true for the therapists. So the essence
- 22:00Speaker 1: of our method is that we are trying to help
- 22:02Speaker 1: people to heal themselves. Are there to provide a safe space.
- 22:07Speaker 1: The MDMA is there to help them process, but people
- 22:11Speaker 1: have to do the hard work. And then once you've
- 22:13Speaker 1: learned that you can process difficult things, then you can
- 22:17Speaker 1: do that on your own without the drug. So that's
- 22:20Speaker 1: where it's again different than classic pharmaceutical drugs where they
- 22:24Speaker 1: you take them every day for years. Sometimes we have
- 22:27Speaker 1: an intervention that several times is to teach people enough
- 22:31Speaker 1: skills and to feel self efficacy that they can process
- 22:35Speaker 1: and heal themselves. That then when they got out into
- 22:38Speaker 1: their life when new traumas happen, they won't be overwhelming,
- 22:43Speaker 1: they'll process them.
- 22:46Speaker 3: I love how empowering it is. And ultimately, whoever's listening
- 22:50Speaker 3: to this, you are the medicine. Sometimes we just need
- 22:52Speaker 3: that reminder and here's this, here's MDMA and here's therapy,
- 22:56Speaker 3: and both combined can totally be that reminder for you.
- 23:00Speaker 3: So for those listening right, accessibility is huge, Like you know,
- 23:05Speaker 3: how can I get this? How soon can I start
- 23:07Speaker 3: this type of therapy and work with this. I mean,
- 23:11Speaker 3: what can you tell folks who are listening, who you know,
- 23:14Speaker 3: don't know much about MDMA and where it is legally
- 23:17Speaker 3: at this point.
- 23:19Speaker 1: Well, it's it's unclear exactly what the FDA wants to
- 23:26Speaker 1: see in terms of additional information before they make it
- 23:29Speaker 1: available as a prescription medicine. So it could be six months,
- 23:32Speaker 1: it could be three years, it's not really clear. But
- 23:36Speaker 1: I do feel that it's important to say that the
- 23:39Speaker 1: drug war itself is counterproductive and I think it's a
- 23:44Speaker 1: fundamental violation of people's human rights to explore their consciousness. So,
- 23:49Speaker 1: you know, you put in the word legal, and so
- 23:53Speaker 1: unfortunately there is no place in the world where MDMA
- 23:58Speaker 1: is legal outs side of a research context. So you
- 24:01Speaker 1: can go to Oregon for psilocybin, you can soon go
- 24:04Speaker 1: to Colorado for psilocybin. You can go to Jamaica, you
- 24:07Speaker 1: can go to Costa Rica for psilocybin. You can go
- 24:09Speaker 1: to South America for ayahuasca. There's no place that people
- 24:12Speaker 1: can go for a legal MDMA experience unless it's in
- 24:16Speaker 1: a clinical trial, and so I think that that's really sad.
- 24:22Speaker 1: And what MAPS is about is sort of these two
- 24:25Speaker 1: parallel paths one is drug development to make mdmaint medicine
- 24:29Speaker 1: through the FDA and then have insurance coverage to cover
- 24:32Speaker 1: the cost of the drug and the therapy. But then
- 24:35Speaker 1: the other is to legalize drug policy reform so people
- 24:38Speaker 1: could do it on their own or with friends, or
- 24:40Speaker 1: you know, without all of this. So I think right
- 24:44Speaker 1: now people have to really decide for themselves. You know,
- 24:51Speaker 1: is the legal status critical to you. If so, you're
- 24:54Speaker 1: going to have to wait for a bunch of years
- 24:57Speaker 1: or six months or we don't know exactly how long,
- 24:59Speaker 1: but it's going to be wait unless you're in a
- 25:01Speaker 1: research project. But if you can think about the laws
- 25:06Speaker 1: as some are good laws, some are bad laws. The
- 25:08Speaker 1: drug war is a bad law, it's counterproductive, then the
- 25:12Speaker 1: question is finding a good MDMA. So there are test
- 25:17Speaker 1: kits you can go to, dance safe things like that
- 25:19Speaker 1: to find that out.
- 25:21Speaker 3: Yeah, harm reduction model definitely ensure that if you are
- 25:24Speaker 3: going to take anything that it isn't mixed with something
- 25:28Speaker 3: you wouldn't want in your body.
- 25:30Speaker 1: Yeah, and also, sorry to interrupt, but there's the treatment Manual,
- 25:34Speaker 1: which is what describes our therapeutic approach. So it's up
- 25:39Speaker 1: for free on the maths website. It's called the Treatment Manual,
- 25:43Speaker 1: and that gives you a sense of these are sort
- 25:45Speaker 1: of the instructions to the therapists of how to work
- 25:48Speaker 1: with someone through the study, and that would be helpful
- 25:51Speaker 1: for people to read.
- 25:52Speaker 2: Thank you for that.
- 25:53Speaker 3: That is amazing, you guys, You guys are amazing in general,
- 25:56Speaker 3: but that you have that out for public knowledge and use,
- 25:59Speaker 3: I appreciate that. And speaking of therapists, so well, let
- 26:03Speaker 3: me go back. So for someone who wants to be
- 26:05Speaker 3: a part of a clinical trial, how do they do that?
- 26:07Speaker 2: How do they go about that?
- 26:08Speaker 1: Well, that part it's easy to figure out. So clinicaltrials
- 26:12Speaker 1: dot gov. Clinical trials dot gov. So it used to
- 26:17Speaker 1: be that pharmaceutical companies, well, pharmaceutical companies have to have
- 26:22Speaker 1: two Phase three studies that are proof safety and efficacy.
- 26:26Speaker 1: But you just need two of them, and a lot
- 26:28Speaker 1: of them. Companies used to like do five or six
- 26:30Speaker 1: studies and you'd never hear about the ones that failed,
- 26:34Speaker 1: never publish them, but you'd only hear about the ones
- 26:36Speaker 1: that succeeded. And that's all that they would submit to
- 26:38Speaker 1: the FDA as a response. Because people felt they weren't
- 26:42Speaker 1: getting the right information. Clinical trials dot gov was set
- 26:45Speaker 1: up so that when you're doing an FDA approved trial,
- 26:48Speaker 1: it has to be listed under Trials dot gov. So
- 26:51Speaker 1: if you go there, you can put in your MDMA
- 26:56Speaker 1: or LSD, or psilocybin or depression or PTSD and it
- 26:59Speaker 1: will and you will find all the clinical trials that
- 27:03Speaker 1: are being conducted with that condition or with those drugs,
- 27:07Speaker 1: or that condition with this drug in this state, so
- 27:11Speaker 1: that you can use clinical Trials dot gov as a
- 27:13Speaker 1: major resource.
- 27:15Speaker 3: Great and for therapists psychologists who want to learn more
- 27:21Speaker 3: about psychedelic assist A therapy. MAPS does offer trainings. How
- 27:26Speaker 3: can they get involved in that if they're interested in
- 27:29Speaker 3: being properly trained?
- 27:31Speaker 1: Yeah, well we've got you can go to the map's website.
- 27:35Speaker 1: I'm leaving in a couple weeks for Ukraine. We're training
- 27:40Speaker 1: Ukrainian therapists. Wow, we've got trainings all over the way.
- 27:45Speaker 1: We've had trainings in Sarajevo, in Iceland and Australia and Israel.
- 27:50Speaker 1: We're planning one in Poland in Switzerland. So you can
- 27:54Speaker 1: go to the map's website and look at training. But
- 28:00Speaker 1: there's not that many opportunities. We haven't had trainings in
- 28:06Speaker 1: the United States for a while. One of the best
- 28:08Speaker 1: things they could do is to consider coming to Psychedelic
- 28:11Speaker 1: Science twenty twenty five. So this is June sixteenth to
- 28:14Speaker 1: twentieth in Denver, and we're going to have workshops from
- 28:18Speaker 1: our leading therapists so you can get a short version
- 28:21Speaker 1: of the training. The basic training is six days and
- 28:25Speaker 1: it's for fifty or fifty five people at a time,
- 28:28Speaker 1: and it goes over the treatment manual what we call
- 28:31Speaker 1: adherence criteria, core competencies, watch videotapes of therapy sessions, do
- 28:37Speaker 1: role play a lot of different exercises and discussions. Then
- 28:44Speaker 1: the second part is optional will always be optional, but
- 28:48Speaker 1: it's for therapists to take the medicine themselves in a
- 28:51Speaker 1: therapeutic setting as if they're the patient, and that's one
- 28:54Speaker 1: of the best ways to learn. It's like you would
- 28:56Speaker 1: never go to an ayahuasca shaman that had never done ayahuasca. Well, yeah,
- 29:02Speaker 1: so we have had FDA PREW protocols. That's again only
- 29:06Speaker 1: in a protocol and it will never be required, only encouraged,
- 29:11Speaker 1: strongly recommended, but never required. And then the third part
- 29:15Speaker 1: is once people work with their first PTSD patients, ideally
- 29:19Speaker 1: it gets at least in our research, it's all videotaped,
- 29:22Speaker 1: and then we have supervisors review the videotapes and give
- 29:26Speaker 1: the feedback to the therapist to see to help them
- 29:29Speaker 1: really fine tune the treatment manual, and then they're free
- 29:34Speaker 1: to practice however they want, you know, to add different
- 29:37Speaker 1: things like that. So I think the treatment. I will
- 29:42Speaker 1: recommend a video called Trip of Compassion. Trip of Compassion.
- 29:47Speaker 1: It's on vimeo. It's the most patient centered video ever
- 29:51Speaker 1: made about mdmasis At therapy. So it's about three of
- 29:54Speaker 1: the Israeli patients. It's mostly in English, the parts of
- 29:58Speaker 1: the Hebrew have English subtitle else and it's gonna be
- 30:03Speaker 1: a really good education and how the therapy actually works.
- 30:07Speaker 2: Okay, great, I didn't even know that existence. So I
- 30:10Speaker 2: appreciate that, yeah, for you know, for when this