Metastatic BRCA-Negative, Triple-Negative Breast Cancer — An Interview with Prof Peter Schmid on Optimal Management (Companion Faculty Lecture)

Research To Practice | Oncology Videos · Sep 22, 2025 · 39m

Featuring a slide presentation and related discussion from Prof Peter Schmid, including the following topics:

Evolution of the therapeutic landscape for metastatic triple-negative breast cancer; age of immunotherapy (0:00)

Case: A woman in her early 40s with no actionable mutations (7:29)

Evolution of antibody-drug conjugates (ADCs) in the management of metastatic breast cancer (11:13)

TROP2-directed ADCs (15:22)

Case: A woman in her early 50s with PD-L1-negative, HR-negative, HER2-low de novo metastatic breast cancer (20:21)

Novel strategies utilizing approved and investigational ADCs…