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New Cell Death Pathway Found in Dementia | Health and Fitness News
Scientists at King’s College London have uncovered a new mechanism of brain cell death called karyoptosis, where the nucleus shrinks and breaks apart due to toxic protein buildup — a key driver in Alzheimer’s and frontotemporal dementia. After a decade of research, they found this process is far more common in diseased brains and identified specific kinase proteins, like p38 MAP kinase, that control it. Blocking these proteins in lab tests reduced karyoptosis, offering a promising new path for therapies aimed at slowing dementia progression by protecting neurons. Listen in comfort:Get a…
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