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Chronic Lymphocytic Leukemia — An Interview with Prof Constantine Tam on Key Presentations from the 2025 ASH Annual Meeting

Featuring an interview with Prof Constantine Tam, including the following topics:

Evolving first-line treatment paradigm for patients with previously untreated chronic lymphocytic leukemia (CLL) (0:00)

Considerations for the administration of first-line venetoclax-based regimens (3:24)

Mechanism of action of sonrotoclax and observed early-phase efficacy in combination with zanubrutinib; minimal residual disease as a potential clinical trial endpoint (10:01)

Continuous versus fixed-duration first-line treatment approaches for previously untreated CLL (14:38)

Selecting between up-front…

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