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The Accidental Pill That Rewrote Women's Hormones
The Accidental Pill That Rewrote Women's Hormones
A single laboratory "mistake" in Berlin produced the first orally active progestogen that would be prescribed to millions of women under more than twenty brand names - but the molecule was never what the chemists intended. How did an attempt to make an oral testosterone become a compound that mimicked progesterone with about 44% receptor affinity, and what dangers rode with that accidental success?
In this episode, we trace the path from a 1938 Schering AG lab to clinics worldwide, detailing the chemical technique that made oral steroid…
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