098-The Global Neurodegeneration Proteomics Consortium

Paper Talk · Sep 28, 2025 · 14m

This paper details the establishment and initial findings of the Global Neurodegeneration Proteomics Consortium (GNPC), a public-private partnership aimed at accelerating the discovery of biomarkers and drug targets for common neurodegenerative diseases like Alzheimer’s, Parkinson’s, Frontotemporal Dementia, and ALS. By assembling one of the world's largest harmonized proteomic datasets from over 35,000 biofluid samples, the consortium overcomes previous barriers related to fragmented research and data sharing. Initial analyses demonstrate the utility of the dataset by identifying…