1656-Tabula Sapiens 2.0: A Atlas of Human Cells

Paper Talk · Oct 8, 2026 · 27m

The research introduces Tabula Sapiens 2.0, an expansive transcriptomic atlas that profiles over 1.1 million individual human cells across 28 different tissues from 24 donors. By utilizing standardized single-cell processing, the Tabula Sapiens Consortium has mapped the expression of nearly all human transcription factors, identifying nearly 900 that exhibit high cell-type specificity. This resource also provides a detailed exploration of cellular senescence, demonstrating that aging-related phenotypes are highly heterogeneous and vary significantly depending on the specific tissue and…