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Mitophagy: The Invisible Process That Quietly Controls Aging, Inflammation, Brain Resilience (and Disease Risk)

Mitophagy is the body’s targeted mitochondrial cleanup system; not general autophagy, but the precise identification and removal of damaged mitochondria so cells can recycle parts and rebuild stronger. In this Deep Dive, Dr. Mike Belkowski breaks down a newly published review, “Mitophagy in the Pathogenesis and Management of Disease,” and explains why mitophagy is more than housekeeping — it’s a strategic control system for mitochondrial integrity, metabolic balance, redox signaling, and immune tone.

You’ll learn the two major mitophagy “toolkits” (ubiquitin-mediated PINK1/Parkin and…

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