Latest / Ageless and Timeless Podcast® / From Neurosurgery to Regenerative Breakthroughs: Stem Cells, Exosomes, and Peptide Innovation with Dr. Jeffrey Gross

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From Neurosurgery to Regenerative Breakthroughs: Stem Cells, Exosomes, and Peptide Innovation with Dr. Jeffrey Gross · Ageless and Timeless Podcast®

• 0:12
  Speaker 1: Good morning everyone.
• 0:13
  Speaker 2: This is Michelle Hughes from Ageless and Timeless. I have
• 0:17
  Speaker 2: a guest today that I've been speaking with for probably
• 0:20
  Speaker 2: six or seven months, but we just were books so
• 0:24
  Speaker 2: solid that we're finally getting to have him on. So
• 0:26
  Speaker 2: doctor Jeffrey Gross, welcome to Ageless and Timeless.
• 0:30
  Speaker 3: Thank you so much.
• 0:31
  Speaker 1: And you're in Nevada, right.
• 0:34
  Speaker 3: I am just outside Las.
• 0:36
  Speaker 1: Vegas, right by Lost Reggae.
• 0:38
  Speaker 3: Did you go to A four M Of course I did.
• 0:40
  Speaker 3: We had a big booth there. Did you come visit?
• 0:42
  Speaker 1: Gosh, I never saw you.
• 0:44
  Speaker 2: Well, you know, with ten thousand whatever it was people there,
• 0:48
  Speaker 2: it was difficult, but yes, I was there as well.
• 0:51
  Speaker 1: It was good. It was probably the best conference ever.
• 0:54
  Speaker 4: It was.
• 0:55
  Speaker 3: It was amazing.
• 0:56
  Speaker 4: It was so many people and so much going on,
• 0:58
  Speaker 4: a lot of energy, and they need to probably you know,
• 1:03
  Speaker 4: out a day.
• 1:04
  Speaker 2: And you know, one of the things we'll talk about
• 1:06
  Speaker 2: today in a little bit is peptides because I think
• 1:09
  Speaker 2: that was one of the hottest subjects at the conference and.
• 1:12
  Speaker 1: They need to do they're going to be doing.
• 1:14
  Speaker 2: They're going to be doing more and more of exploration
• 1:18
  Speaker 2: and both themselves and peptides.
• 1:19
  Speaker 1: But let's start first with with your background.
• 1:22
  Speaker 2: So you know, and I see that you went to
• 1:24
  Speaker 2: school in Berkeley, so you were you were in my backyard.
• 1:28
  Speaker 1: For a while.
• 1:29
  Speaker 4: Yes, yes, I'm a Golden Bear from UC Berkeley way
• 1:34
  Speaker 4: back in the eighties and uh, it was just as
• 1:37
  Speaker 4: crazy then as it probably is now.
• 1:40
  Speaker 1: Yeah, I was here, that was.
• 1:41
  Speaker 2: I came in seventy three to Tiberon and I went
• 1:47
  Speaker 2: through all the violence and you know that kind of
• 1:51
  Speaker 2: stuff with Berkeley and hate Ashbury and all that.
• 1:54
  Speaker 1: So yeah, so we were. I was here a.
• 1:56
  Speaker 2: Little bit before you, but still, you know, then you
• 1:59
  Speaker 2: you got So how did you go from uh, chemistry,
• 2:04
  Speaker 2: biological what was biochemistry and molecular biology to regenerative medicine
• 2:11
  Speaker 2: neurosurgery and regenerative medicine. How did that all happen? Give
• 2:15
  Speaker 2: us your little background on your journey.
• 2:19
  Speaker 4: Well, I'm I'm a nerd, so I'm always following cool science.
• 2:23
  Speaker 4: So biochemistry was a really fun degree for me in college.
• 2:27
  Speaker 4: It offered you know a lot of cutting edge cellular
• 2:32
  Speaker 4: you know.
• 2:32
  Speaker 3: Biology, molecular biology.
• 2:34
  Speaker 4: They've actually changed the name of the degree now it's
• 2:37
  Speaker 4: called molecular cell biology, which makes more sense. But that
• 2:42
  Speaker 4: was that's the field where stem cells kind of reside.
• 2:46
  Speaker 4: But at that time, you know, stem cells were you know,
• 2:50
  Speaker 4: barely mentioned they were.
• 2:51
  Speaker 3: They were a new concept.
• 2:53
  Speaker 4: So then I went to medical school and then residency
• 2:55
  Speaker 4: and fellowship neurological surgery. The nervous system was of of
• 2:59
  Speaker 4: great interest to me, sort of the final frontier at
• 3:02
  Speaker 4: that time, you know, and I pursued that.
• 3:04
  Speaker 3: I enjoyed it.
• 3:06
  Speaker 4: I did a fellowship in spinal biomechanics. I did spinal medicine,
• 3:11
  Speaker 4: always trying ways not to do surgery because surgery is
• 3:15
  Speaker 4: so overdone. And that's why spine surgery has such a
• 3:19
  Speaker 4: bad reputation, and it should because there are real, real
• 3:23
  Speaker 4: hacks out there, just operating on what the MRI shows,
• 3:26
  Speaker 4: not what the patient needs.
• 3:27
  Speaker 1: So, Jeffrey, why do you think that is?
• 3:31
  Speaker 4: It's, uh, the tail is wagging the dog, Michelle. It's
• 3:34
  Speaker 4: the the payer mix, the scripted sick care nonsense. And
• 3:43
  Speaker 4: you know, the the revenue from being pushed by what's
• 3:49
  Speaker 4: called big implant. You've heard a big pharma. Well, we
• 3:51
  Speaker 4: have what's called big implant. They make all the screws
• 3:53
  Speaker 4: and rods to you know, put in people. So they
• 3:56
  Speaker 4: push it and they they they push it down through
• 4:00
  Speaker 4: the payers and through the institutions, the hospitals, and it's
• 4:06
  Speaker 4: it's not patient centric anymore. It's it's business centric. It's
• 4:11
  Speaker 4: the medical industrial complex. So that's why.
• 4:14
  Speaker 1: Yeah.
• 4:14
  Speaker 2: So, was there any one pivotal moment in your journey
• 4:19
  Speaker 2: that made you.
• 4:21
  Speaker 1: Turn to that.
• 4:24
  Speaker 3: No, there wasn't one pivotal moment.
• 4:26
  Speaker 4: But I do give credit to patients who came into
• 4:29
  Speaker 4: my office many times saying, hey, and I've tried all
• 4:32
  Speaker 4: these treatments. I tried therapies and injections and medicines and
• 4:35
  Speaker 4: time and yoga and all these things in my spy.
• 4:39
  Speaker 3: My back hurts, my neck hurts. It's not better.
• 4:41
  Speaker 4: And I'd say, well, I guess the next thing on
• 4:43
  Speaker 4: the menu is talk about surgery. They said, well, wait
• 4:46
  Speaker 4: a minute, I'm not that bad. I don't want surgery.
• 4:48
  Speaker 4: I said, okay, great, because I really didn't want to
• 4:50
  Speaker 4: have to do it. And they'd say, well, it's got
• 4:52
  Speaker 4: to be something else to try. What about stem cells?
• 4:54
  Speaker 4: What about stem cells?
• 4:55
  Speaker 1: What?
• 4:55
  Speaker 4: You just keep hearing it, And I say, you know what,
• 4:58
  Speaker 4: I have background in that. Instead of going to the
• 5:02
  Speaker 4: annual spine surgery conference, I'm going to go to a
• 5:04
  Speaker 4: stem cell conference. I'm going to start to see what's new,
• 5:07
  Speaker 4: retrain myself. And it was eye opening and now eight
• 5:10
  Speaker 4: years later it's all I do.
• 5:13
  Speaker 1: So tell us more about that. How that works.
• 5:17
  Speaker 4: Yeah, we we do what's called regeneritive medicine. It's a
• 5:20
  Speaker 4: strategy of using the body's own healing capability that that's
• 5:25
  Speaker 4: very robust during our youth, but it loses its own
• 5:30
  Speaker 4: later in life, and we we reactivate it using signals,
• 5:35
  Speaker 4: and those signals are stem cells or stem cell signaling
• 5:40
  Speaker 4: items like exosomes and growth factors and peptides, and and
• 5:45
  Speaker 4: we we reanimate some of the body's own abilities that
• 5:51
  Speaker 4: get clogged up with inflammation and oxidative stress over the years.
• 5:57
  Speaker 4: And we do that strategically in different ways for different
• 5:59
  Speaker 4: peace people, and we help them turn back on the
• 6:03
  Speaker 4: anti inflammatory healing youthful process to help restore a joint,
• 6:08
  Speaker 4: improve osteoarthritis, improve their body's ability to fight an autoimmune
• 6:14
  Speaker 4: or other inflammatory issue. And many diseases of aging are
• 6:18
  Speaker 4: related to some element of inflammation. So when we're fighting inflammation,
• 6:22
  Speaker 4: we're putting cells back into a more optimal mode where
• 6:25
  Speaker 4: they can do what they're supposed to do.
• 6:28
  Speaker 2: Is there a cutoff in age that you see in
• 6:31
  Speaker 2: your practice where the stem cells just become useless or dormant,
• 6:36
  Speaker 2: or is it really patient individualized based on lifestyle and
• 6:41
  Speaker 2: other possibly epigenetics and other reasons.
• 6:45
  Speaker 1: You know, what do you say about aging.
• 6:47
  Speaker 2: As are the chronological age as an indicator for stem
• 6:52
  Speaker 2: cell activation?
• 6:55
  Speaker 4: Well, look, I like to keep the things simple. I
• 6:58
  Speaker 4: do know that you can use your own stem cells.
• 7:00
  Speaker 4: They do lose activity and number with age and with
• 7:06
  Speaker 4: epigenetic lifestyle behaviors that maybe weren't ideal.
• 7:10
  Speaker 3: And some of those things aren't our fault.
• 7:12
  Speaker 4: Right, We've been eating food and vegetable oils and things
• 7:15
  Speaker 4: in our food source and water that we are now
• 7:17
  Speaker 4: looking at saying, oh, we shouldn't have had.
• 7:19
  Speaker 3: These things right. They were bad. These preservatives were bad.
• 7:22
  Speaker 4: So you know, our cells and our stem cells become
• 7:27
  Speaker 4: less powerful. So I never take my car to get
• 7:33
  Speaker 4: it serviced and have them put the old oil back in,
• 7:35
  Speaker 4: even if it's a new car. I always get fresh oil.
• 7:37
  Speaker 4: So I love the most youthful source. Even if you're
• 7:43
  Speaker 4: you know, in your thirties and you're looking to heal
• 7:46
  Speaker 4: a knee, I could take your own cells, But then
• 7:49
  Speaker 4: I got a harvest them, and we got to prepare them.
• 7:51
  Speaker 4: It's easy to use some of the off the shelf
• 7:54
  Speaker 4: donated biologics that are very ethical and safe that are
• 7:58
  Speaker 4: related to a section birth. So the mother gets the
• 8:02
  Speaker 4: child congratulations, can we have your amniotic fluid. You're in
• 8:06
  Speaker 4: bilical cord, you're placental. You're not using them anymore. We're
• 8:09
  Speaker 4: gonna throw them away, you know. So I think that's
• 8:13
  Speaker 4: the most efficient and most powerful way to do regener
• 8:17
  Speaker 4: in medicine.
• 8:18
  Speaker 2: Are you competing with the medical community about advising the patient,
• 8:23
  Speaker 2: the mother in this case, to bank their own childs
• 8:28
  Speaker 2: themselves for future That's one of the you know, the
• 8:31
  Speaker 2: big new things that seems to be happening in that
• 8:35
  Speaker 2: world of of pediatrics.
• 8:40
  Speaker 3: Yeah, I don't know that we're competing for that.
• 8:42
  Speaker 4: And I think that you know, a lot of people
• 8:44
  Speaker 4: are banking their their new babies, you know, in bilical cord,
• 8:49
  Speaker 4: because you can use those tissues later for that child
• 8:53
  Speaker 4: and for family members and probably for anyone if they're
• 8:56
  Speaker 4: handled properly. So banking them just improves the availability of them.
• 9:02
  Speaker 2: It's actually better for you for later on in their lives.
• 9:05
  Speaker 2: It just makes the supply a little bit more or
• 9:09
  Speaker 2: means that you have to look a little further maybe
• 9:11
  Speaker 2: to get those stem cells where the mother hasn't been
• 9:15
  Speaker 2: that interested in doing that. But I just came back
• 9:19
  Speaker 2: from Well in November. I came back from the Town
• 9:22
  Speaker 2: Center in Tijuana.
• 9:25
  Speaker 1: I don't know, do you have you ever heard of
• 9:26
  Speaker 1: in Clay and the Well.
• 9:29
  Speaker 2: It's the place that Joe Rogan touts on his podcast
• 9:32
  Speaker 2: and Dana white is I think he's an.
• 9:36
  Speaker 1: Investor or whatever.
• 9:37
  Speaker 2: But they're one of the leading hospitals and they're doing
• 9:41
  Speaker 2: a lot of work with cancer too. But they offered
• 9:46
  Speaker 2: nad ivs plus they always dound treatment, plus the stem cells.
• 9:51
  Speaker 2: And so anyway, I was the only one of fifty
• 9:54
  Speaker 2: of people that came. I went because I wanted to
• 9:57
  Speaker 2: meet Ed and he was coming on my pod cash
• 10:00
  Speaker 2: and you know, he was very kind to allow me.
• 10:04
  Speaker 1: To participate in what the other people went through.
• 10:07
  Speaker 2: But the other forty nine people were all doing injections
• 10:12
  Speaker 2: of stem cells, and I because I had, thank goodness,
• 10:17
  Speaker 2: nothing to that was bothering me that, you know, I
• 10:20
  Speaker 2: was more longevity and proactive health. I did the IV
• 10:29
  Speaker 2: so I did one hundred and twenty million stem cells.
• 10:31
  Speaker 1: So my question to you is, is you know.
• 10:34
  Speaker 2: In my case, I had no sign that I even
• 10:38
  Speaker 2: did it. In the case of the other forty nine
• 10:40
  Speaker 2: people that did the injectables with the umbilical court, the
• 10:45
  Speaker 2: same thing that you use, they were all in horrible
• 10:49
  Speaker 2: pain and they had a WhatsApp link, so everybody was
• 10:54
  Speaker 2: talking to each other. Even after they returned to.
• 10:57
  Speaker 1: The United States.
• 11:00
  Speaker 2: For weeks, it seemed that people were saying, I can't
• 11:04
  Speaker 2: move my shoulder, you know, my ankle herds.
• 11:09
  Speaker 1: So my question to you is when you do the.
• 11:12
  Speaker 2: Grain part of this, does that happen or is that
• 11:16
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• 12:12
  Speaker 4: No, no, we have a more advanced approach to this,
• 12:15
  Speaker 4: and on many levels we don't have these type of problems.
• 12:18
  Speaker 4: So for the brain the best delivery, let's take a
• 12:22
  Speaker 4: step back. Actually, okay, stem cells don't last but a
• 12:26
  Speaker 4: few days in your body, but their benefits last well
• 12:30
  Speaker 4: beyond that. Some of them are permanent benefits. Those stem
• 12:34
  Speaker 4: cells when you get them IV eighty percent of them
• 12:37
  Speaker 4: and get hung up in your heart and lungs, which
• 12:39
  Speaker 4: is great for your heart and lungs, but the rest
• 12:41
  Speaker 4: of your body doesn't get much.
• 12:43
  Speaker 1: Okay, So that's me, that's my So that what happened
• 12:47
  Speaker 1: to me.
• 12:47
  Speaker 2: So I've got a great benefit in my heart and
• 12:49
  Speaker 2: my lungs.
• 12:51
  Speaker 4: So probably the stem cells are gone in a day
• 12:55
  Speaker 4: or two, but they have delivered to your body the
• 12:59
  Speaker 4: signaling through what we call extracellular vesicles or exostomes and
• 13:04
  Speaker 4: growth factors. Well, we can skip the cells and we
• 13:09
  Speaker 4: can go right to the extracellular vesicles or exosomes and
• 13:14
  Speaker 4: the growth factors, and then it doesn't get hung up
• 13:16
  Speaker 4: in your heart and munks because there are a thousand
• 13:18
  Speaker 4: times smaller. They cross the blood brain barrier. Your brain
• 13:21
  Speaker 4: gets a bigger amount. They're more fluid throughout the body,
• 13:25
  Speaker 4: they travel better through tissue, and that's what we're using now.
• 13:28
  Speaker 4: That's the more advanced way to signal. They're also less
• 13:31
  Speaker 4: costly because they're more abundant. They come from amniotic fluid.
• 13:35
  Speaker 4: Umbilical cord is small, the amniotic sack is large, full
• 13:40
  Speaker 4: of fluid. So these are the stem the effect of
• 13:44
  Speaker 4: the stem cell without the cells. Plus stem cells have
• 13:46
  Speaker 4: DNA someone else's DNA. Not that we think that's an issue,
• 13:50
  Speaker 4: but a lot of people don't like the idea of
• 13:53
  Speaker 4: getting genes from someone else, especially after the whole COVID
• 13:56
  Speaker 4: vaccine fiasco, which has inserted RNA into yourselves.
• 14:02
  Speaker 2: Right, I was just going to ask you that was
• 14:04
  Speaker 2: my next question is how do you ensure that these
• 14:07
  Speaker 2: donors have not had the vaccine or the MRM are
• 14:11
  Speaker 2: a corruption in their body.
• 14:16
  Speaker 4: We only draw the suppliers I use because I don't
• 14:19
  Speaker 4: I don't source these myself. I get them from a supplier.
• 14:21
  Speaker 4: The supplier I use and vetted and visited the lab
• 14:26
  Speaker 4: has only drawing from a COVID vaccination free pool.
• 14:29
  Speaker 1: Of mothers, which is very limited. Not really, Okay, well
• 14:34
  Speaker 1: that's good. I mean I wanted them. I mean I'm
• 14:37
  Speaker 1: not a mother to draw from. But I thought I was.
• 14:40
  Speaker 2: One of the very mighty big minority, given how people
• 14:43
  Speaker 2: were career.
• 14:45
  Speaker 1: Into getting the vaccine. But you're saying there are still
• 14:48
  Speaker 1: plenty of people. Maybe they were just very silent, right those.
• 14:51
  Speaker 3: Yes, that's true. It was the silent majority.
• 14:55
  Speaker 1: Particularly if they were pregnant.
• 14:57
  Speaker 2: Yeah, so many women who were pregn and got the
• 15:00
  Speaker 2: vaccine and have you know, had problems. So more and
• 15:04
  Speaker 2: more people are finding out that's a whole other subject,
• 15:06
  Speaker 2: but they're finding out the side effects after the fact.
• 15:10
  Speaker 1: Unfortunately that this is this is just the beginning of
• 15:14
  Speaker 1: the exposure of that.
• 15:17
  Speaker 2: Right, So when you go to a donor or to supplier,
• 15:24
  Speaker 2: how do you ensure, Jeffrey that that supplier is efficacious?
• 15:30
  Speaker 4: Well, I'm glad you asked me that. So first we
• 15:34
  Speaker 4: look at the source or in this case, healthy mothers
• 15:37
  Speaker 4: screened on the first trimester on prenatal vitamins, no smoking,
• 15:41
  Speaker 4: no drugs, only one romantic partner during the pregnancy, no
• 15:45
  Speaker 4: COVID vaccine, no disease history, so it's a curated group.
• 15:51
  Speaker 4: And then they're screened again at the time of birth
• 15:54
  Speaker 4: and they also you know, again a health panel.
• 15:58
  Speaker 3: Then the materials are.
• 16:00
  Speaker 4: Handled in accordance with the American Tissue Bank accredited services,
• 16:07
  Speaker 4: and they're on ice.
• 16:09
  Speaker 3: They go to the lab.
• 16:10
  Speaker 4: The lab then quarantines them for two weeks to check
• 16:12
  Speaker 4: for endotoxin cultures, make sure it doesn't grow.
• 16:15
  Speaker 3: Anything it shouldn't have in it.
• 16:17
  Speaker 4: They check it for both protein content which is the
• 16:20
  Speaker 4: growth factors, and the extracellular vesical count.
• 16:24
  Speaker 3: And they only.
• 16:25
  Speaker 4: Count the round vesicles between fifty and one hundred and
• 16:28
  Speaker 4: fifty nanometers in diameter.
• 16:30
  Speaker 3: Now, all those specifications you don't need to memorize.
• 16:32
  Speaker 4: It's technical, but this is the highest current way to
• 16:38
  Speaker 4: evaluate these type of biologic Now that doesn't speak to efficacy,
• 16:43
  Speaker 4: but we know those are the cleanest and safest way
• 16:47
  Speaker 4: to get that youthful signal, the same youthful signal a
• 16:50
  Speaker 4: pregnant mother gets when her hair is growing and her
• 16:54
  Speaker 4: skin is glowing.
• 16:57
  Speaker 2: So, after you've done the placement of the stem cells
• 17:03
  Speaker 2: in the in your patient, what normally happens within like
• 17:07
  Speaker 2: let's say the first week or.
• 17:09
  Speaker 1: So of them having those stem cells.
• 17:11
  Speaker 2: At where they are now being somewhat transported somewhere. So
• 17:16
  Speaker 2: what what do you what do you most frequently see
• 17:20
  Speaker 2: as a reaction when you get those stem cells into
• 17:24
  Speaker 2: the into your.
• 17:25
  Speaker 4: Patient, so intravenous again, these are these are not stem cells,
• 17:30
  Speaker 4: they're stem cell signals signals.
• 17:33
  Speaker 1: Right, I should have said that. I'm sorry.
• 17:35
  Speaker 4: That's okay, I got you. This is for educational purposes.
• 17:38
  Speaker 4: Everyone gets to hear it, right. The We typically see
• 17:43
  Speaker 4: improvement in energy, sleep, mental speed and clarity, UH, recovery
• 17:52
  Speaker 4: from exercise workouts, Reduced inflammatory markers if we do blood tests,
• 17:58
  Speaker 4: significant improvement and heart rate variability or HRV for those
• 18:02
  Speaker 4: people that track it.
• 18:03
  Speaker 3: Using a ring or a whoop or a.
• 18:05
  Speaker 4: Watch device, and improvement and aches and pains that have
• 18:11
  Speaker 4: inflammatory origin.
• 18:12
  Speaker 3: We also see reduction.
• 18:14
  Speaker 4: In biological age tests, so you effectively might get a
• 18:17
  Speaker 4: little younger, you know, biologically for that.
• 18:21
  Speaker 2: And what about dimension and Alzheimer's and you know other
• 18:25
  Speaker 2: illnesses that affect the brain. Are is that oftentimes this
• 18:31
  Speaker 2: symptoms that you're trying to change and correct.
• 18:35
  Speaker 3: I would I would approach that differently, Michelle.
• 18:38
  Speaker 4: For people with inflammatory based brain problems, traumatic brain injury,
• 18:42
  Speaker 4: recovering from stroke, Parkinson's, Alzheimer's dementia has an inflammatory component.
• 18:49
  Speaker 4: We're using nasal spray exosomes. They actually have better delivery
• 18:52
  Speaker 4: nasal than they do IV. So people commit for a
• 18:56
  Speaker 4: simple nasal spray and tend to have reduction in the symptoms,
• 19:01
  Speaker 4: and our Parkinson's patients have reduction in the need for
• 19:04
  Speaker 4: the parkinson medications.
• 19:07
  Speaker 2: So what's in those nasal sprays.
• 19:11
  Speaker 4: The same stem cell derived exosomes and growth factors that's
• 19:16
  Speaker 4: in amniotic fluid, okay.
• 19:18
  Speaker 2: And then what about the peptides like slang and cimacs.
• 19:21
  Speaker 3: And yeah, great question.
• 19:25
  Speaker 4: We like to stack those with appropriate peptides, you know,
• 19:29
  Speaker 4: customized for the individual of course, and based on you know,
• 19:33
  Speaker 4: looking at labs and everything else. We don't like to
• 19:35
  Speaker 4: add a lot of things at the same time. We
• 19:38
  Speaker 4: like to add one thing at a time so we
• 19:39
  Speaker 4: can really measure what's making a difference or determined if
• 19:44
  Speaker 4: it's a combination of things that's making a difference. So
• 19:47
  Speaker 4: so we do like to add the peptides, certain peptides
• 19:50
  Speaker 4: for certain issues. Sometimes it's a mitochondri peptide they need that.
• 19:56
  Speaker 1: Would be epicalon like for an example as one.
• 20:00
  Speaker 3: Specifically, I meant that SS thirty one and.
• 20:03
  Speaker 1: Or Mott's C would be the.
• 20:06
  Speaker 4: Two most common mitochondria specific signaling signaling peptides.
• 20:11
  Speaker 2: Well, I know, I'm under Bill Lawrence, who's the peptide
• 20:15
  Speaker 2: bioregulator guru. He worked for doctor Cavinson was his mentor.
• 20:20
  Speaker 1: And if you're familiar with the.
• 20:22
  Speaker 2: Oral peptides, he's the head guy in the US. So anyway,
• 20:27
  Speaker 2: I've known him for and he's been on my podcast.
• 20:30
  Speaker 2: He sent me the nasal spray for epitalon. I think
• 20:34
  Speaker 2: I'm saying you're right epichalon, but he says that they lengthen.
• 20:39
  Speaker 2: That lengthens you're telomere. So telomerase is a big factor
• 20:43
  Speaker 2: in mitochondria or biological aging and mitochondria pell So that's
• 20:48
  Speaker 2: why I asked you.
• 20:50
  Speaker 4: Yes, you're correct. Epitelon is a great longevity peptide, and
• 20:56
  Speaker 4: one of the measures is the telomere length. Although telomere
• 20:59
  Speaker 4: length is a good thing, it by itself doesn't beget longevity.
• 21:03
  Speaker 3: There's so much more to do, that's.
• 21:05
  Speaker 2: True, So give us some results that you know, just
• 21:10
  Speaker 2: case study. A couple of examples of how this has changed,
• 21:15
  Speaker 2: particularly when the peptides are stacked, as people are now
• 21:18
  Speaker 2: more curious about combining stem cells, stem cells and peptides,
• 21:23
  Speaker 2: and then even the eggs zones like you said and
• 21:27
  Speaker 2: so on. So you're right at the cutting edge. So
• 21:30
  Speaker 2: give us a cutting edge picture of what it's like
• 21:34
  Speaker 2: to be under your care, what the patients typically is
• 21:38
  Speaker 2: happening in a couple of your success stories.
• 21:42
  Speaker 3: Thank you for that.
• 21:43
  Speaker 4: Yes, well, you know I'm here in Las Vegas, so
• 21:46
  Speaker 4: most of our patients find me on podcasts like this one,
• 21:48
  Speaker 4: I hope and they will. We start remotely, so we
• 21:53
  Speaker 4: do video just like we're doing here. We get any
• 21:56
  Speaker 4: imaging results, we get any lab tests. We can order
• 22:00
  Speaker 4: things in your hometown. So we have people that are
• 22:03
  Speaker 4: across the country Canada, the UK, South Africa, and Australia
• 22:08
  Speaker 4: that we've been talking to, and we only invite people
• 22:13
  Speaker 4: here to our home in Las Vegas if there's something
• 22:17
  Speaker 4: we can do for them, if there's a reason not
• 22:19
  Speaker 4: everyone's a candidate. Most of what I do, because remember
• 22:23
  Speaker 4: I'm a recovering spine surgeon, is I do joints and spine.
• 22:27
  Speaker 4: So we isolate a pain generator that has an inflammatory component,
• 22:34
  Speaker 4: very high quality MRIs, not just a run of the
• 22:36
  Speaker 4: mill MRI. And I like to be involved in that
• 22:40
  Speaker 4: because I know how to order off the secret menu
• 22:43
  Speaker 4: on MRIs and then we target off the MRI and
• 22:48
  Speaker 4: then we bring people here. So let's say it's a knee,
• 22:50
  Speaker 4: we do a lot of these. These are the low
• 22:52
  Speaker 4: hanging fruit. So we bring people here, we already know
• 22:55
  Speaker 4: what we're going to do, and we do the injections
• 22:59
  Speaker 4: per a European protocol, and that protocol calls for us
• 23:04
  Speaker 4: not to inject the joint, but to inject the bone
• 23:07
  Speaker 4: edge above and below the joint. And the reason for
• 23:11
  Speaker 4: that is one the cartilage we're trying to stimulate and
• 23:15
  Speaker 4: regenerate is made in the bone.
• 23:17
  Speaker 3: Just like our.
• 23:18
  Speaker 4: Hair is made in our scalp follicle, but sent out
• 23:24
  Speaker 4: of our scalp to hang on our head. Our cartilage
• 23:28
  Speaker 4: is made in our bones. So injecting the cartilage where
• 23:32
  Speaker 4: there are very few cells isn't so useful. And that's
• 23:37
  Speaker 4: why those patients in Tijuan are getting so inflamed, because
• 23:40
  Speaker 4: you're putting a bunch of cells in their joint, which
• 23:42
  Speaker 4: is called you know, it's called arthritis. You're giving them
• 23:45
  Speaker 4: a temporary cellular arthritis. So we inject the bone edge.
• 23:50
  Speaker 4: Of course, we do some light sedation in a surgery center,
• 23:54
  Speaker 4: I use fluoroscopy and we target off the MRI, I
• 23:58
  Speaker 4: match the fluoroscopy and we go right into the spot.
• 24:01
  Speaker 4: The procedure doesn't take long at all. People have a
• 24:03
  Speaker 4: little bit of soreness for up to a week, but
• 24:06
  Speaker 4: there's no downtime. So it's nothing like the people you
• 24:09
  Speaker 4: experienced in Tijuana, which is which, and there's nothing wrong
• 24:13
  Speaker 4: with what they're doing. It's it was tried and true
• 24:15
  Speaker 4: in the two thousands, two thousand and five, twenty ten,
• 24:18
  Speaker 4: and a lot of clinics still do it because they're
• 24:20
  Speaker 4: not equipped or knowledgeable to catch up with the European
• 24:23
  Speaker 4: literature where there's fifteen year follow up publication showing that
• 24:28
  Speaker 4: the bone edge injection is years superior to the joint injection.
• 24:34
  Speaker 4: So that's what we're doing. We're doing this at the
• 24:36
  Speaker 4: highest level, at the most advanced level, and we stack
• 24:39
  Speaker 4: that with a cartilage regeneration peptide and a wolverine stack.
• 24:46
  Speaker 4: So it's BPC one five seven TV five hundred cartill
• 24:50
  Speaker 4: acts at a good dose, and it's injectable subcutaneous. The
• 24:55
  Speaker 4: oral is not bioavailable enough for this purpose.
• 24:59
  Speaker 1: That's a good point. That's really helpful. Jeffrey.
• 25:01
  Speaker 2: You know, I was told this is just a question
• 25:05
  Speaker 2: for you, But I was told that because I know
• 25:07
  Speaker 2: the Wolverine stack very well.
• 25:09
  Speaker 1: But I was told that.
• 25:12
  Speaker 2: TV five hundred is less expensive but not nearly as
• 25:16
  Speaker 2: effective as SIMS beta four.
• 25:19
  Speaker 1: What are your thoughts.
• 25:21
  Speaker 3: From a muscular skeletal perspective.
• 25:23
  Speaker 4: I haven't seen head to head comparisons to be able
• 25:26
  Speaker 4: to speak to that. The Wolverine combo is so affordable
• 25:31
  Speaker 4: anyway that I think it's a big deal. We love
• 25:36
  Speaker 4: thymusin peptides for immune health and prevention. I love TV
• 25:43
  Speaker 4: five hundred, which is thymysin beta you know in the
• 25:47
  Speaker 4: wolverine stack because it's angiogenic. It supports the development of
• 25:50
  Speaker 4: blood flows, so you need that when you're regenerating tissues.
• 25:55
  Speaker 4: So the BPC is heavily anti inflammatory, the TB five
• 25:58
  Speaker 4: hundred is heavily angiog. You put those together, you get
• 26:01
  Speaker 4: the synergy. Add the cardillacs or the cartilage degeneration. Make
• 26:06
  Speaker 4: sure you're getting good protein, intake creatine, and you know,
• 26:11
  Speaker 4: good amount of protein and and then you need to
• 26:13
  Speaker 4: mechanically stimulate the joint. We want our patients who have
• 26:16
  Speaker 4: these injections to be using the joint the next day.
• 26:20
  Speaker 4: It's the mechanical stimulation and mecounter receptors need to feel
• 26:26
  Speaker 4: that to stimulate the process.
• 26:29
  Speaker 2: And what about the people that have already had a
• 26:31
  Speaker 2: surgery and maybe they have titanium and their joints wherever
• 26:36
  Speaker 2: the surgery was, how do you deal with overcoming the
• 26:40
  Speaker 2: metal of the titanium in getting to the place where
• 26:44
  Speaker 2: they're going to heal or do they have to have
• 26:47
  Speaker 2: the titanium removed before they can even begin with you.
• 26:52
  Speaker 4: Yeah, so unfortunately, if you've had a knee replacement, you've
• 26:55
  Speaker 4: got titanium there. There isn't an approach that we have
• 26:59
  Speaker 4: for those people. And very few people, if anyone, is
• 27:02
  Speaker 4: going to have that removed. So it's unfortunately they've burned
• 27:08
  Speaker 4: the bridge once they've had the replacement.
• 27:11
  Speaker 2: Okay, but but you can have it removed if a
• 27:14
  Speaker 2: person says, okay, I'll go back and take this.
• 27:17
  Speaker 1: Out now it's been a few years. No, they can't
• 27:20
  Speaker 1: do that.
• 27:21
  Speaker 4: We speaking to a knee, they they remove your meniscus
• 27:25
  Speaker 4: and your cartilage in the bone, part of the bone
• 27:27
  Speaker 4: to put in the artificial knee. So no, you can't
• 27:30
  Speaker 4: have that out. It leaves you with a big wobbly nothing.
• 27:35
  Speaker 1: What about what.
• 27:35
  Speaker 2: About if it's in another place, like an ankle, like
• 27:38
  Speaker 2: a tippy fibula type.
• 27:39
  Speaker 4: Of thing, if it's a true replacements.
• 27:43
  Speaker 2: But that's not true replacement, that's just chipping and fibula
• 27:46
  Speaker 2: being broken and being supported right by the Titanic.
• 27:51
  Speaker 4: Okay, so now you're talking about like a fracture repair
• 27:55
  Speaker 4: hardware exactly. Yes, we prefer that be removed as soon
• 28:00
  Speaker 4: as the fractures healed.
• 28:02
  Speaker 3: We don't like retained hardware.
• 28:05
  Speaker 4: You know that that does put additional stress at the joint,
• 28:09
  Speaker 4: and it's really begging for advanced and accelerated arthritis development.
• 28:15
  Speaker 4: We Starthritis were saying post traumatic degenerative arthritis. I hate
• 28:19
  Speaker 4: the word arthritis because it's so misused by doctors and others.
• 28:23
  Speaker 2: Yeah, but okay, so what if somebody says, Okay, I've
• 28:26
  Speaker 2: waited a couple of years to do this procedure, and
• 28:30
  Speaker 2: so I've had the injury, the insult, but I haven't
• 28:33
  Speaker 2: done and checked the BFC. Let's say, into the joint
• 28:37
  Speaker 2: because I've heard that would work, but it didn't work
• 28:39
  Speaker 2: for me.
• 28:40
  Speaker 1: I'm just giving you hypotheticals.
• 28:42
  Speaker 2: So what would you tell that patient how to You know,
• 28:44
  Speaker 2: there's been kind of bandating it without going to the
• 28:48
  Speaker 2: step of meeting with someone like you.
• 28:51
  Speaker 4: Well, most people are trying different things first, and that's okay.
• 28:56
  Speaker 4: We're not doing peptides in the joint. I've not seen
• 28:59
  Speaker 4: evidence that that is any better than injecting it subcutaneously
• 29:04
  Speaker 4: into your belly fat, So we recommend subcutaneous injection or
• 29:09
  Speaker 4: nasal spray, depending on the application.
• 29:11
  Speaker 2: That's a really good point because like stem cells that
• 29:14
  Speaker 2: are pluryot the peptides that say BPC, just to use
• 29:20
  Speaker 2: that because that's the most commonly known. If you injected
• 29:23
  Speaker 2: the SubQ into the abdomen, h does it have a
• 29:26
  Speaker 2: brain to know where to go, just like stem cells
• 29:30
  Speaker 2: do to the place that is the.
• 29:33
  Speaker 4: Healing peptides go throughout the body, throughout the body, right,
• 29:39
  Speaker 4: But where you need it most is where you'll hopefully
• 29:42
  Speaker 4: feel the most benefit. That that's not to say maybe
• 29:45
  Speaker 4: helping prevent and do help you in other areas as well,
• 29:48
  Speaker 4: So why not do that. But but just to clarify,
• 29:51
  Speaker 4: stem cells there are different kinds of stem cells. We're
• 29:54
  Speaker 4: not currently using pluripotent stem cells. Those are we don't
• 29:59
  Speaker 4: you know, we're learning about out them. There are certain
• 30:01
  Speaker 4: applications in the cancer realm we are using you know
• 30:05
  Speaker 4: what we's called multipotent stem cells.
• 30:07
  Speaker 3: You know, Okay, yeah, I.
• 30:09
  Speaker 2: Understand that, so, but maybe explain the difference to people,
• 30:12
  Speaker 2: because not everybody understands that.
• 30:14
  Speaker 1: So if you could take a moment just to tell
• 30:17
  Speaker 1: difference is so.
• 30:19
  Speaker 4: When you when you're a fertilized egg inside of your
• 30:22
  Speaker 4: mother's womb, you're you're omniple. You're made of one omnipotent
• 30:27
  Speaker 4: stem cell, and that that develops into you know, a
• 30:31
  Speaker 4: fetus that has limbs and things, and the cells there
• 30:34
  Speaker 4: can still make a body and organs. Those are pluripotent.
• 30:37
  Speaker 4: They have a lot of power, but not as much
• 30:38
  Speaker 4: as the original embryo. And then eventually when you come
• 30:41
  Speaker 4: out and are born, you maintain mainly multipotent stem cells.
• 30:46
  Speaker 4: So they can't go back and form a limb, although
• 30:49
  Speaker 4: we're learning potentially how to do that, but they can
• 30:52
  Speaker 4: help replace and regenerate tissue and stimulate your body's healing.
• 30:56
  Speaker 4: Those are called multipotent and that's really front therapy peutic perspective.
• 31:01
  Speaker 4: What's out there here available except in a few isolated,
• 31:06
  Speaker 4: research controlled situations where we use induced pluripotent where they're
• 31:11
  Speaker 4: nudged backwards with some tiny growth factors called Yamanaka factor that's.
• 31:15
  Speaker 1: Right, I know all about them. Yeah, so talk about
• 31:18
  Speaker 1: those for a moment.
• 31:19
  Speaker 2: I'm glad you brought that up, because there's more and
• 31:21
  Speaker 2: more on the internet now about the Yamanaka factors. And
• 31:24
  Speaker 2: I don't think everybody understands how important that study of
• 31:28
  Speaker 2: that revelation was and how it got ignored. So could
• 31:32
  Speaker 2: you go through that for us, just to give us
• 31:35
  Speaker 2: a little history of what's happened, what did happen.
• 31:38
  Speaker 1: And what has now happening.
• 31:40
  Speaker 4: So, yeah, doctor Yamanaka isolated what it takes to take
• 31:46
  Speaker 4: a sell and move it back into its stem in
• 31:52
  Speaker 4: its plural potent origin, and so you're moving it backwards
• 31:56
  Speaker 4: along these embryonic lines, and you can do it with
• 31:58
  Speaker 4: four little growth factors that are called the Yamanaka factors.
• 32:03
  Speaker 4: And uh so you you know you give it.
• 32:06
  Speaker 1: These Why do you think that I'm sorry to interrupted.
• 32:09
  Speaker 1: Why did you get it suppressed over these years?
• 32:13
  Speaker 2: Why has why has it not been more groundbreaking and utilized.
• 32:19
  Speaker 4: If you were a company that made billions of dollars
• 32:22
  Speaker 4: selling chemicals, uh to sick people, you wouldn't want to
• 32:27
  Speaker 4: find the fountain of youth.
• 32:29
  Speaker 5: Yeah, yeah, so that's that's so they didn't find that
• 32:34
  Speaker 5: the pharmaceutical companies didn't weren't able to patent the yamanaka factors.
• 32:41
  Speaker 3: As trying as I'm sure they're trying.
• 32:44
  Speaker 1: Yeah, okay, well follow the money.
• 32:46
  Speaker 2: As we always say, this is a problem with our
• 32:49
  Speaker 2: healthcare system right that we're not looking to cure the cause,
• 32:54
  Speaker 2: the root cause, but yet we find lots and lots
• 32:57
  Speaker 2: of drugs to try to address symptoms.
• 33:02
  Speaker 3: We could talk another hour on that. I'll just cut
• 33:06
  Speaker 3: it off there because there's so much I could say.
• 33:08
  Speaker 2: But I try to keep this podcast a political even
• 33:11
  Speaker 2: though you know I have my opinions, but I you know,
• 33:16
  Speaker 2: I try to keep it it's neutral. It's more educational
• 33:19
  Speaker 2: rather than political. But obviously you know I have a
• 33:24
  Speaker 2: strong belief in regenerative and functional medicine.
• 33:27
  Speaker 1: That's why I do this because I want people who are.
• 33:30
  Speaker 2: Still practicing in the traditional old fashioned way and getting
• 33:33
  Speaker 2: no help, no results, to understand that there are solutions,
• 33:38
  Speaker 2: but you have to look.
• 33:39
  Speaker 1: Further into what people like you are doing.
• 33:42
  Speaker 2: So that's really seven years ago when I began this podcasts.
• 33:46
  Speaker 1: That was really my.
• 33:48
  Speaker 2: Goal is to help people, is to be almost a
• 33:51
  Speaker 2: philanthropic resource for people to have more. You know, information
• 33:56
  Speaker 2: is power. So how is a robotics accepting what you do? Well?
• 34:04
  Speaker 3: You know, AI is We're just tapping into that, right.
• 34:08
  Speaker 4: So sometimes I will use AI to help find patterns
• 34:13
  Speaker 4: and things I can't see because a doctor uses is
• 34:16
  Speaker 4: a pattern recognizer. But sometimes that pattern's not obvious. So
• 34:20
  Speaker 4: we'll put labs in. We'll say, hey, help me out here,
• 34:22
  Speaker 4: what's a list of things, and you know you might
• 34:25
  Speaker 4: find something you didn't consider. So we use it to
• 34:27
  Speaker 4: open our minds. I hopefully or hopefully people do. I
• 34:31
  Speaker 4: use AI also to save time, you know, help me,
• 34:35
  Speaker 4: here's some notes I made on a patient. Please put
• 34:37
  Speaker 4: this in a nice paragraph form or something like that.
• 34:39
  Speaker 3: That's simple.
• 34:41
  Speaker 4: We're using you know, our companies using AI to find
• 34:43
  Speaker 4: new peptides that bind certain receptors.
• 34:47
  Speaker 3: So that's really meat.
• 34:48
  Speaker 4: And I just came back from a health tech summit
• 34:51
  Speaker 4: a couple of weeks ago in your neck of the
• 34:53
  Speaker 4: woods in the city and we there was a lot
• 34:57
  Speaker 4: of talk on you know, how to how to to
• 35:00
  Speaker 4: employ AI better in healthcare and and and use And
• 35:05
  Speaker 4: I think what we're going to find, at least in
• 35:06
  Speaker 4: the next year or two, using AI to read an
• 35:10
  Speaker 4: X ray or an MRI or a pathological specimen is
• 35:13
  Speaker 4: going to have more efficiency and more thoroughness than we've
• 35:18
  Speaker 4: ever had and speed.
• 35:21
  Speaker 1: And what about robotics.
• 35:23
  Speaker 4: So robotics, you know, I trained a little late after
• 35:27
  Speaker 4: robotics came through. I know I have colleagues that use robotics.
• 35:31
  Speaker 4: And in the spine surgery realm, I went to see
• 35:34
  Speaker 4: a robot. A robot used to help with spine surgy
• 35:36
  Speaker 4: is a great way to take a surgery and add
• 35:38
  Speaker 4: three hours to it. So, you know, until it becomes
• 35:43
  Speaker 4: an efficiency generator, it's going to be held up a
• 35:47
  Speaker 4: little bit and so.
• 35:49
  Speaker 2: But yet you're using it for heart surgery and for
• 35:52
  Speaker 2: things that are a lot more.
• 35:54
  Speaker 1: But I don't mean just being demean of what you're doing.
• 35:58
  Speaker 2: But you know, i'd say a heart surgeon like doctor Gundry,
• 36:02
  Speaker 2: I mean that that's life and death.
• 36:06
  Speaker 1: You would hope it can be.
• 36:08
  Speaker 4: It can be, Yeah, not the brain surgery that I
• 36:11
  Speaker 4: used to do wasn't either, and we used to tease
• 36:14
  Speaker 4: the heart surgeons and they're just there to make sure
• 36:16
  Speaker 4: the brain gets supplied.
• 36:18
  Speaker 2: Yeah, no, I was thinking not too much brain surgery,
• 36:20
  Speaker 2: but like me, replacements.
• 36:23
  Speaker 1: Yeah, that more more the joint muscle issues that you
• 36:27
  Speaker 1: that you also deal with.
• 36:29
  Speaker 2: So tell me, tell us about the muse and you
• 36:34
  Speaker 2: put you gave me a list of topics and I
• 36:38
  Speaker 2: didn't understand.
• 36:39
  Speaker 1: I didn't know what that was.
• 36:40
  Speaker 2: So could you explain that to us and how you're
• 36:43
  Speaker 2: using that the muse muse stem cell.
• 36:45
  Speaker 1: M U s E.
• 36:47
  Speaker 4: Yeah, So, as I alluded to earlier, there are many
• 36:49
  Speaker 4: types of stem cell.
• 36:50
  Speaker 3: I give you the overarching headings.
• 36:52
  Speaker 4: Turns out there's a subset of of regular umbilical UH
• 36:58
  Speaker 4: cord stem cells, which are mainly MSCs called MUSE mus
• 37:03
  Speaker 4: standing for a multi lineage undifferentiated stress enduring.
• 37:07
  Speaker 3: So they're a little bit better and they have.
• 37:10
  Speaker 4: More potential, and they're smaller so they'll travel better through tissue.
• 37:14
  Speaker 4: So we're just now learning how to apply these. They
• 37:17
  Speaker 4: become popularized, you know, because the Kardashian's got some, but
• 37:21
  Speaker 4: we are just gaining access to them, and we are
• 37:25
  Speaker 4: expecting to be trying them in some of our challenging areas.
• 37:29
  Speaker 4: So for example, the spinal disc is difficult to regenerate
• 37:33
  Speaker 4: even with regular MSCs or exosomes. We have benefit using
• 37:39
  Speaker 4: those biologics in the spinal bones and in the spinal joints,
• 37:44
  Speaker 4: but not so much in the disc. But there was
• 37:46
  Speaker 4: a study out of China and they do try things
• 37:49
  Speaker 4: there early where they use muse cells and showed some
• 37:53
  Speaker 4: disc regenerations. So we are looking to begin as soon
• 37:56
  Speaker 4: as we get our hands on these, which hopefully will
• 37:58
  Speaker 4: be the next few months. A disk sandwich therapy will
• 38:02
  Speaker 4: do muse cells in the disc in the nucleus of
• 38:04
  Speaker 4: the disc, because that's tissue of what's called endodermal origin,
• 38:09
  Speaker 4: and then we'll use typical MSc derived exosomes and growth
• 38:14
  Speaker 4: factors in the bone edge as we have been doing
• 38:17
  Speaker 4: traditionally to stimulate the disc annulysts and the endplate health.
• 38:21
  Speaker 4: And that sandwich therapy we're hoping is a breakthrough in
• 38:25
  Speaker 4: our ability to improve the health of our discs.
• 38:29
  Speaker 1: And where do those the meuse cells come from versus
• 38:33
  Speaker 1: the ones.
• 38:33
  Speaker 4: That you have been using from the umbilical They also
• 38:38
  Speaker 4: come from the umbilical source but they have to be
• 38:41
  Speaker 4: carefully teased out because they're you know, maybe one percent
• 38:45
  Speaker 4: of them. So that's that's where they become difficult to
• 38:50
  Speaker 4: collect enough. It's like panning for gold. You have to
• 38:54
  Speaker 4: sift through a lot of river bed to find enough gold,
• 38:58
  Speaker 4: you know, to make an it.
• 39:01
  Speaker 2: And so just I'm not sure I'm really understanding the
• 39:04
  Speaker 2: differentiation between how they make a difference and how the
• 39:08
  Speaker 2: regular the stem cells you've been using make a difference.
• 39:11
  Speaker 1: So what is it that they are that make a difference.
• 39:15
  Speaker 4: They can stimulate different tissues in our body better than
• 39:20
  Speaker 4: regular MSCs. Okay, yeah, and again challenging areas like the
• 39:25
  Speaker 4: disc like hair growth. Uh, you know, we use we
• 39:30
  Speaker 4: have some benefits from using exosomes and stem cells in
• 39:33
  Speaker 4: the scalp for hair growth, but there are still challenging
• 39:37
  Speaker 4: cases and we think the muse cells are going to
• 39:38
  Speaker 4: move that.
• 39:39
  Speaker 3: Along for us.
• 39:39
  Speaker 4: In addition to the right other health you know, aspects
• 39:43
  Speaker 4: and lifestyle factors and peptides.
• 39:46
  Speaker 1: And what have you got it? Okay, that helps, Thank you.
• 39:50
  Speaker 2: I don't think anybody listening today or watching today would
• 39:54
  Speaker 2: even have known about those muse cells. So this is
• 39:57
  Speaker 2: something that everybody can learn from and even ask if
• 40:01
  Speaker 2: they need this help, they can ask their practitioner.
• 40:05
  Speaker 1: So, okay, let's move on to another subject. What in
• 40:11
  Speaker 1: your practice so far?
• 40:12
  Speaker 2: You've obviously made a big transition from molecular biology to
• 40:18
  Speaker 2: regenerative medicine and away from surgery as much as possible.
• 40:23
  Speaker 2: Has there been any incredible insight or learning experience that
• 40:29
  Speaker 2: you've had in your journey to do that to make
• 40:33
  Speaker 2: that those changes and along with that correlating, has there
• 40:38
  Speaker 2: been any failure that has taught you some great lessons?
• 40:43
  Speaker 1: I know that's probably a double when.
• 40:46
  Speaker 3: We can handle compound questions. The first one is, you know,
• 40:52
  Speaker 3: I think that you look.
• 40:54
  Speaker 4: At root cause analysis and you know, it's amazing how
• 41:00
  Speaker 4: much inflammation plays a role in degenerating the effect of ourselves,
• 41:07
  Speaker 4: and how we can biologically signal through regenerative biologics, through
• 41:13
  Speaker 4: peptides and other ways through lifestyle to really slow and
• 41:18
  Speaker 4: even reverse that inflammation for health and longevity benefits. So
• 41:22
  Speaker 4: I think that's the aha moment that we we lost
• 41:24
  Speaker 4: sight of. We probably learned it in medical school or before,
• 41:27
  Speaker 4: but we lost sight of it. We're so busy treating
• 41:29
  Speaker 4: knee pain or back pain or you know, So that's
• 41:32
  Speaker 4: the root cause piece there. And you know, the the
• 41:37
  Speaker 4: failures would be in you know, doing doing surgery when
• 41:44
  Speaker 4: for all these years and you know, in the right
• 41:46
  Speaker 4: patient and doing it as best as I could, when
• 41:49
  Speaker 4: I could have been offering them regenerative medicine options because
• 41:54
  Speaker 4: informed consent, the doctrine of informed consent means a doctor
• 41:58
  Speaker 4: has to tell a patient all the options, review the
• 42:01
  Speaker 4: risks and benefits, the pros and cons and help that
• 42:04
  Speaker 4: patient make a good decision, you know, an educated decision.
• 42:07
  Speaker 4: If we're not giving them all the options, we are
• 42:09
  Speaker 4: violating that doctrine exactly. So so many doctors who are
• 42:13
  Speaker 4: not including these options. And we don't have to offer
• 42:16
  Speaker 4: the option. If I don't do a certain thing, I
• 42:18
  Speaker 4: can say, listen, this is an option. I'd have to
• 42:20
  Speaker 4: send you somewhere to go get that.
• 42:23
  Speaker 3: That's okay. We we should be doing that, and so
• 42:25
  Speaker 3: many are not.
• 42:26
  Speaker 4: They're just doing what's scripted or in some even worse, Sorry, ma'am,
• 42:31
  Speaker 4: I really want to do this surgery.
• 42:33
  Speaker 3: But the insurance will cover this other one, so we'll
• 42:35
  Speaker 3: do the one they'll cover, right.
• 42:36
  Speaker 1: That's that's just discussing the sickness of our system.
• 42:41
  Speaker 2: That, you know, people can only do what they are
• 42:44
  Speaker 2: covered by insurance, and oftentimes insurance is not covering the
• 42:47
  Speaker 2: very protocols that they would benefit the most by.
• 42:52
  Speaker 1: Correct it's crazy.
• 42:52
  Speaker 2: I hope, I hope that RFK can do some things
• 42:56
  Speaker 2: that his position to modify or at least dramatically change that.
• 43:02
  Speaker 2: But okay, So, so in the stem cell world, is
• 43:07
  Speaker 2: there anything that's happening besides these use cells? Is there
• 43:10
  Speaker 2: anything else that's happening that it's exciting you that you
• 43:14
  Speaker 2: have found out about when you went to this conference
• 43:16
  Speaker 2: or otherwise?
• 43:18
  Speaker 1: Oh?
• 43:18
  Speaker 4: Yeah, Well, so in the next year or two, you know,
• 43:21
  Speaker 4: the word the phrase stem cell will be will be
• 43:25
  Speaker 4: too vague to use. We'll be talking about, well, what
• 43:28
  Speaker 4: kind of what tissue specific stem cell? Is it a
• 43:31
  Speaker 4: neurologic stem cell? Is it an exosome derived from a
• 43:34
  Speaker 4: neurologic stem cell? I just ordered my first batch of
• 43:38
  Speaker 4: what's called dermal papilla xisomes, which are specific for the
• 43:42
  Speaker 4: follicles and the hair that have a enhanced cargo and
• 43:48
  Speaker 4: signal for hair growth on top compared to a generic exosome.
• 43:53
  Speaker 3: Nothing wrong with generic exisomes.
• 43:55
  Speaker 4: They're healthy, they give a good signal but if we
• 43:57
  Speaker 4: can dial that signal and even better, it's like dial
• 44:00
  Speaker 4: in the old UHFTV to they get the signals just
• 44:03
  Speaker 4: a little tighter.
• 44:04
  Speaker 3: That's what we're going to be hearing about.
• 44:07
  Speaker 1: Yeah, you know, I didn't realize that you were working
• 44:11
  Speaker 1: on the scalp.
• 44:12
  Speaker 2: I mean that's a huge area because particularly for women
• 44:17
  Speaker 2: after menopause.
• 44:18
  Speaker 1: So talk a little bit about, you.
• 44:22
  Speaker 2: Know, the patients that you have and what kind of
• 44:26
  Speaker 2: results you've gotten from the hair growth standpoint.
• 44:31
  Speaker 4: Yeah, you know, we use a lot of MSc derived
• 44:35
  Speaker 4: exisomes and growth factors, the amniotic fluid products in the
• 44:39
  Speaker 4: scalp and in the face for cosmetic it's really an
• 44:42
  Speaker 4: enhanced vampire facial, right. Because of vampire facial you take
• 44:46
  Speaker 4: your own PRP, your own blood, and you injected in
• 44:48
  Speaker 4: the face or the scalp, and those can be beneficial,
• 44:51
  Speaker 4: but the exosomes are even more beneficial.
• 44:56
  Speaker 3: Typically, we like to use a fresh frozen variety.
• 45:00
  Speaker 4: I don't like the powdered liophalyzed because you lose a
• 45:03
  Speaker 4: lot of the growth factors. You lose some of the
• 45:05
  Speaker 4: exosomes when you powder them, So we use fresh frozen.
• 45:09
  Speaker 4: We have a special freezer we keep all that in
• 45:11
  Speaker 4: and we have variable results. We inject the scalp, we
• 45:14
  Speaker 4: inject the face for rejuvenation of the skin quality, especially
• 45:19
  Speaker 4: like you said, after menopause, there's skin dryness, itchiness, flakiness, redness,
• 45:26
  Speaker 4: and we want to improve the skin quality.
• 45:28
  Speaker 3: We're working on.
• 45:31
  Speaker 4: A cream that you would keep at home in the refrigerator.
• 45:36
  Speaker 4: That would be the same amniotic contents in a cosmetic
• 45:42
  Speaker 4: product that should be launched here in the next couple
• 45:44
  Speaker 4: of months. But you have to keep a refrigerator because
• 45:48
  Speaker 4: these things are viable, they're biologically active. It's not going
• 45:54
  Speaker 4: to be something you're going to get off the shelf
• 45:57
  Speaker 4: at Sephora.
• 46:00
  Speaker 1: Do the treatment you're talking about.
• 46:03
  Speaker 2: Obviously, people have to travel to Las Vegas to your clinic,
• 46:07
  Speaker 2: right and to do this is not You can't just
• 46:10
  Speaker 2: use the cream at home as a band aid without.
• 46:15
  Speaker 3: You can use the cream at home once it's available.
• 46:17
  Speaker 3: We don't have it yet in market. We will.
• 46:20
  Speaker 1: You can order that.
• 46:21
  Speaker 3: It'll be cold shipped.
• 46:22
  Speaker 4: We're figuring all those details out. Yeah, we're trying to
• 46:26
  Speaker 4: come up with a name. So if any of your
• 46:27
  Speaker 4: listeners can help us out there. Yeah, you know, so
• 46:31
  Speaker 4: many people are scooping up all the good website domains,
• 46:35
  Speaker 4: so we want to name and we can get the domain,
• 46:36
  Speaker 4: you know, So we're trying that. But yeah, that should
• 46:40
  Speaker 4: be launched very shortly, and that's separate or in addition
• 46:43
  Speaker 4: to the procedures. The procedure just micro needles. So we
• 46:46
  Speaker 4: do micro needles and then we put on the put
• 46:49
  Speaker 4: in or put on the exosomes, and sometimes we'll put
• 46:53
  Speaker 4: a little hyaluronic paint on top of it just to
• 46:57
  Speaker 4: steal them in.
• 46:58
  Speaker 2: Right.
• 46:59
  Speaker 1: Well, that's exciting. I was a part of your practice.
• 47:01
  Speaker 1: I had no idea what you were doing, and so
• 47:04
  Speaker 1: there's lots of people.
• 47:05
  Speaker 2: That opens up a huge floodgate of people who might
• 47:08
  Speaker 2: be interested in contacting you about your procedures because.
• 47:14
  Speaker 1: There is so much money spent on hair replacement but
• 47:18
  Speaker 1: with no results.
• 47:20
  Speaker 4: You know, hair is multifactorial, you know, hormones and inflammatory burden.
• 47:27
  Speaker 3: In the body.
• 47:27
  Speaker 4: There's so many things we look at for that, and
• 47:31
  Speaker 4: you know, we have great success in some and not
• 47:33
  Speaker 4: as great for others. That's why we're excited to try
• 47:36
  Speaker 4: these dermal papilla exosomes for the more challenging cases of
• 47:39
  Speaker 4: the muse cells. For some of the more challenging cases,
• 47:42
  Speaker 4: so we will have different things worth trying as as
• 47:46
  Speaker 4: we progress in gaining knowledge and understanding in the field
• 47:50
  Speaker 4: of you know, regenerative biologics.
• 47:54
  Speaker 1: So how often do they have to have those treatments
• 47:56
  Speaker 1: to make a real impact.
• 48:00
  Speaker 4: Usually do them in a series of three separated by
• 48:03
  Speaker 4: four to six weeks if we can. Of course, people
• 48:05
  Speaker 4: traveling in can always do that, but it does take
• 48:09
  Speaker 4: a number of weeks or months to see the growth
• 48:12
  Speaker 4: spurt through the top, you know, the scalp and start
• 48:16
  Speaker 4: to come in. And oddly, some of these have a
• 48:18
  Speaker 4: temporary shedding phase, so you actually lose a little hair
• 48:21
  Speaker 4: at the beginning, which can be quite daunting. So we're
• 48:24
  Speaker 4: gaining more understanding there so we can advise people what
• 48:28
  Speaker 4: to look for.
• 48:30
  Speaker 2: So, Jeffrey, before we have to go, because they just
• 48:33
  Speaker 2: signaled me, I want to ask you a personal question.
• 48:36
  Speaker 2: What is your what are your daily habits that have
• 48:41
  Speaker 2: kept you healthy and not needing all these procedures that
• 48:45
  Speaker 2: we're talking about.
• 48:47
  Speaker 4: Well, I do I do intravenous exosomes quarterly just for
• 48:52
  Speaker 4: preventive purposes.
• 48:54
  Speaker 1: I do.
• 48:56
  Speaker 4: You know, I'm very good with making sure I'm getting
• 49:00
  Speaker 4: a good weight bearing exercise, you know, lifting heavy, using
• 49:04
  Speaker 4: my muscles, working the core. I also try to you know,
• 49:09
  Speaker 4: have a nice sleep hygiene, you know, cooler room, turning
• 49:14
  Speaker 4: off the screens early. I intermittent feed I'm a guy
• 49:18
  Speaker 4: who easily doesn't have to eat until lunchtime. And we're
• 49:21
  Speaker 4: filming this now, We're approaching noon here in the Pacific
• 49:25
  Speaker 4: time zone, and I'm just now thinking I could I
• 49:27
  Speaker 4: could go for something I.
• 49:28
  Speaker 1: Have that I'm exactly the same way, you know, and
• 49:31
  Speaker 1: sometimes I eat. I finished my last meal by seven
• 49:34
  Speaker 1: or six even, and I don't need again until the
• 49:37
  Speaker 1: next day at this time.
• 49:39
  Speaker 2: So yeah, I'm getting like those you know, eighteen to
• 49:42
  Speaker 2: twenty two hours of intermittent fasting. Ye doctor Anton who
• 49:47
  Speaker 2: is a guest on my podcast, he runs the l neutro,
• 49:50
  Speaker 2: which is real. I know, Yeah they have the fasting
• 49:55
  Speaker 2: with food, but he says you shouldn't do more than
• 49:58
  Speaker 2: sixteen hours.
• 49:59
  Speaker 1: But I don't know.
• 50:00
  Speaker 2: For me, I find that you know, longer doesn't do
• 50:04
  Speaker 2: any make any difference in my muscle, you know, an
• 50:08
  Speaker 2: atrophy or you know, the m chore or any of
• 50:11
  Speaker 2: the prophety. It just seems like it doesn't make a
• 50:14
  Speaker 2: difference whether it's sixteen or twenty hours.
• 50:17
  Speaker 1: Just I just feel better when I haven't had to digest.
• 50:23
  Speaker 3: I listen to my body.
• 50:24
  Speaker 4: When I get hungry, i'll eat something and I don't.
• 50:26
  Speaker 4: I'm not eating much because the rest of my regimen.
• 50:29
  Speaker 4: And I could make a longer list, but I take supplements,
• 50:32
  Speaker 4: but we do peptides. So I'm on a low dose redditruetide.
• 50:35
  Speaker 4: Some people call it retatritide. That's fine, what you want.
• 50:40
  Speaker 4: I call it redta or for fun, I call it
• 50:42
  Speaker 4: strata true tide because it really, you know, give me
• 50:45
  Speaker 4: abs again and.
• 50:47
  Speaker 3: That I've been on now, I've been on a GLP
• 50:50
  Speaker 3: of some form for about three and a half years,
• 50:53
  Speaker 3: and I love just not being hungry all the time.
• 50:56
  Speaker 3: So that's been great.
• 50:57
  Speaker 1: And so you micro doose it? How is it ten mL?
• 51:00
  Speaker 3: You don't know if micro dosing is the right word.
• 51:03
  Speaker 1: Well, how much do you do? And how often?
• 51:06
  Speaker 3: I'm on two milligrams a week?
• 51:09
  Speaker 1: That's very low. It's okay.
• 51:13
  Speaker 2: I only know it by the insulin needle. So what's
• 51:16
  Speaker 2: two milligrams daily on an insulin needle?
• 51:19
  Speaker 1: If you were doing it? You don't know.
• 51:21
  Speaker 3: This depends on your concentration, is what you've got yeah.
• 51:26
  Speaker 4: And and for those of you out there in the
• 51:27
  Speaker 4: peptide world, if someone asks you your dose and you
• 51:30
  Speaker 4: tell us in units, we have no idea what your
• 51:32
  Speaker 4: dose is. You have to tell us how many how
• 51:35
  Speaker 4: many milligrams are in the vile, how many ccs of
• 51:38
  Speaker 4: fluid you used to make it up. Then we know
• 51:39
  Speaker 4: your concentration and we can calculate the dose. So we
• 51:43
  Speaker 4: do retitrue tie. We do CLO with copper, so that's
• 51:47
  Speaker 4: BBC one five seven, TV five hundred, KPV and TV
• 51:51
  Speaker 4: and k GHK.
• 51:57
  Speaker 3: We do a low dose. My wife and I do
• 51:59
  Speaker 3: a Lodos every night, and then we do a higher
• 52:03
  Speaker 3: dose nights of need.
• 52:06
  Speaker 4: If we're taking the kids to Disneyland or the grandkids
• 52:08
  Speaker 4: to Disneyland and we're gonna get twenty five thousand steps,
• 52:11
  Speaker 4: we're gonna take a higher dose that night, so we
• 52:14
  Speaker 4: dial it up and down. I do take ipomorland cjc
• 52:20
  Speaker 4: W one twenty five for muscle maintenance, and then I
• 52:25
  Speaker 4: have been using some little melanotan too, so I'm usually
• 52:30
  Speaker 4: very very pale, especially on the podcast. You know, the
• 52:33
  Speaker 4: light wipes it out. I have a little bit of
• 52:35
  Speaker 4: freckles in color now because of the Milana town.
• 52:38
  Speaker 1: Yeah, that would be the last thing I should ever
• 52:40
  Speaker 1: do because I have so much melanin. But but I
• 52:42
  Speaker 1: know the value of it.
• 52:43
  Speaker 2: For people who are of let's say, Irish descent, they
• 52:47
  Speaker 2: want some more tanning. But I am more Mediterranean, so
• 52:51
  Speaker 2: I stay away from that. That's the one step, Jove,
• 52:54
  Speaker 2: that I don't do. But I try all the other
• 52:55
  Speaker 2: ones you mentioned. I amusing so but I try to
• 53:00
  Speaker 2: keep it to like, you know, a very low dose of.
• 53:03
  Speaker 1: Everything, but at least I'm getting something. Yeah.
• 53:06
  Speaker 2: Well, I know our time was up, and I want
• 53:08
  Speaker 2: to thank you for sharing all this incredibly valuable information.
• 53:12
  Speaker 1: I'm glad we finally got our chance to have this exchange.
• 53:18
  Speaker 2: Is there anything that you want to say in parting
• 53:21
  Speaker 2: ways to our viewers, any last minute pearl of wisdom?
• 53:26
  Speaker 3: Yeah? You so thank you for having me, Michelle. So
• 53:29
  Speaker 3: everyone out there, you don't have to spend a lot
• 53:31
  Speaker 3: of money to live longer.
• 53:33
  Speaker 4: Exercise hard, breathe deep yoga breaths periodically, get up out
• 53:39
  Speaker 4: of your chair, out of the couch, move around, do
• 53:42
  Speaker 4: some squats, exercise snacks, try to avoid the seed oils.
• 53:47
  Speaker 1: You can do this.
• 53:48
  Speaker 3: You can live longer.
• 53:49
  Speaker 1: Yeah, and sleep is an important one to I agree
• 53:53
  Speaker 1: with that too. Okay, thank you.
• 53:55
  Speaker 2: You have been a great guest. It's been a pleasure
• 53:57
  Speaker 2: having you on the show and sharing the comversation with
• 54:00
  Speaker 2: our audience. To everyone listening, thank you for tuning in.
• 54:04
  Speaker 2: If you enjoyed this episode, be sure to subscribe, share
• 54:08
  Speaker 2: it with someone who would benefit, and join us again
• 54:12
  Speaker 2: for the next conversation. Until then, take care and stay well.