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1439-The Brain as a Dynamic Immunological Interface

Modern scientific research has overturned the traditional view of the brain as an isolated, "immune-privileged" organ, instead revealing it to be a dynamic immunological interface. Key discoveries such as the meningeal lymphatic vessels and the glymphatic system demonstrate that the central nervous system actively drains waste and communicates with the peripheral immune system. The blood-brain barrier is no longer seen as an impenetrable wall but as a selective gateway where microglia and astrocytes actively manage inflammation and tissue repair. Furthermore, external factors like gut…

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