Latest / Stuff You Should Know / 10 Scientists Who Were Their Own Guinea Pigs
Transcript
- 0:00Speaker 1: Brought to you by the reinvented two thousand twelve Camray.
- 0:03Speaker 1: It's ready. Are you welcome to stuff you should know
- 0:08Speaker 1: from House toff works dot com. Sometimes science goes too
- 0:16Speaker 1: far dog matters twisted but true. Wednesday's attend on Science. Hey,
- 0:25Speaker 1: and welcome to the podcast. I'm Josh Clark with me
- 0:28Speaker 1: at long last is Charles W. Chuck Bryant. And this
- 0:32Speaker 1: is special like eight ways from Sunday? This episode is,
- 0:37Speaker 1: isn't it. I've changed my name over the weekend. Yeah,
- 0:40Speaker 1: I've changed the jan Michael Vincent finally. All right, you've
- 0:46Speaker 1: been talking about that forever, Chuck. I'm glad you finally
- 0:49Speaker 1: did it. And you showed me your driver's license and
- 0:51Speaker 1: it's official. Pretty neat. And what's cool is, um you
- 0:54Speaker 1: did your hair for the photo. It looks kind of
- 0:57Speaker 1: like the air Wolf Airwolf era, Jane Michael Vincent. Is
- 1:00Speaker 1: there any other era the Mechanic? That's true? That those
- 1:04Speaker 1: are his two eras Hooper. Was he in that? Yeah?
- 1:08Speaker 1: He was the young buck stuntman to Burt Reynolds's aged veteran.
- 1:12Speaker 1: Really he played that role a couple of times. Then
- 1:14Speaker 1: I guess, huh, okay, Well, that's enough for the Jim
- 1:18Speaker 1: Michael Vincent shout outs. Is he around still? Uh? I
- 1:22Speaker 1: mean I haven't seen him in a decade and he
- 1:25Speaker 1: was in pretty bad shape a decade ago. Was he
- 1:26Speaker 1: really Yeah? From the from what I think drugs, I
- 1:30Speaker 1: might be wrong though, or maybe he was not. He
- 1:34Speaker 1: was injured or something. Do you just told everybody Jim
- 1:36Speaker 1: Michael Vincent likes drugs. He's self experimented. Great one, Thank
- 1:41Speaker 1: you very much for that. Um. This is a special
- 1:43Speaker 1: episode because we are good good friends of the Science
- 1:45Speaker 1: Channel and they have a very very cool show that
- 1:50Speaker 1: an ad played for at the beginning of this episode,
- 1:53Speaker 1: Dark Matters. It comes on. It premiered last Wednesday. It
- 1:56Speaker 1: comes on tomorrow Wednesdays at ten pm. Have you have
- 2:00Speaker 1: you looked at the episodes? Have you seen any of
- 2:02Speaker 1: the video? It's pretty awesome. It is UM and I
- 2:04Speaker 1: was going through the episode guide of the stuff they
- 2:06Speaker 1: have coming up. It's like, um, really like a dark
- 2:10Speaker 1: version of Unsolved Mysteries? Remember that? Yeah? Yeah? So UM.
- 2:15Speaker 1: The A couple of the episodes have stuff that we've covered,
- 2:18Speaker 1: like Einstein's brain, c I A lsd UM, and then
- 2:22Speaker 1: they have a bunch of stuff we have. I didn't
- 2:26Speaker 1: get that impression, but it's it's possible. They can do
- 2:28Speaker 1: anything they want. But imitation is the greatest form of flighters, right,
- 2:32Speaker 1: And that's actually we get asked to do stuff sometimes
- 2:34Speaker 1: and you'll know if we really want to do it
- 2:36Speaker 1: because we do it. And we did this one. Like
- 2:39Speaker 1: this is literally being recorded today. Yeah, Like that's crazy.
- 2:44Speaker 1: That is definitely different. Yeah, Jerry's turning this one around
- 2:47Speaker 1: like hours later. Yeah, or earlier. We recorded this. It
- 2:50Speaker 1: is as fresh as it gets. It still has the
- 2:52Speaker 1: peach fuzz on it. Depeche Mode. By the way, de
- 2:55Speaker 1: pech Mode is in no way related to a rare
- 2:58Speaker 1: the founding He was a founding member of the h
- 3:00Speaker 1: Mode and later went on to Founderation. Really Vincent Clark really, yes, wow,
- 3:05Speaker 1: I knew there was some tie. I had no idea
- 3:08Speaker 1: we're talking about this because we were having rarely do
- 3:10Speaker 1: we let you in on our pre record conversation. But
- 3:14Speaker 1: Josh went saw Ratio this weekend and I knew it
- 3:15Speaker 1: was awesome and it was great, and there was some
- 3:18Speaker 1: tie to another band. I couldn't remember it, and it
- 3:20Speaker 1: was depeche Mode. Well, it was either depeche Mode or
- 3:22Speaker 1: the pet Boys, probably, but I had cheez Did I
- 3:26Speaker 1: just say that that? He said the pet Boys, which
- 3:28Speaker 1: is an auto part score. They're really good on the
- 3:32Speaker 1: keyboards and they had these gigant or heads and bodies.
- 3:35Speaker 1: All right, So Chuck, you're ready ready. We're talking about
- 3:40Speaker 1: scientists who self experiment and we've talked about UM crazy
- 3:43Speaker 1: experiments before. So this UM episode actually forms a trifecta
- 3:48Speaker 1: with two other previously released episodes that if you haven't heard,
- 3:52Speaker 1: you should go listen to. What's the third UM? There
- 3:54Speaker 1: is the human Experimentation sure episode, and then five Crazy
- 3:59Speaker 1: Government exp Oh yeah, all those are pretty pretty well
- 4:03Speaker 1: mixed together. So if you listen to that the if
- 4:06Speaker 1: you listen to those two and self Experimentation, you're gonna
- 4:08Speaker 1: have a very robust understanding of just how nuts some
- 4:12Speaker 1: scientists are. You know what they call that around here?
- 4:14Speaker 1: What a bucket? Yeah, they do a bucket of content. Heck,
- 4:18Speaker 1: that's almost channel. That's right. Ah, this is good man.
- 4:22Speaker 1: You threw this together like lickety split last week and
- 4:25Speaker 1: found some really cool things. I think. Yeah, there's there's
- 4:29Speaker 1: UM you could do way more than ten Yeah, sure, UM,
- 4:32Speaker 1: like the guy who cracked his own knuckles for thirty years,
- 4:36Speaker 1: just in his left hand. I believe he found nothing right.
- 4:39Speaker 1: It does not cause arthritis. Um. We've talked before about
- 4:42Speaker 1: Albert Hoffman, the Swiss chemist who um took the world's
- 4:47Speaker 1: first acid trip that's on purpose, Um, on a bike.
- 4:51Speaker 1: But can you imagine like never having known anything about it,
- 4:57Speaker 1: Like I think generally when people do that kind of
- 4:59Speaker 1: thing these days, you've heard of it and you know
- 5:01Speaker 1: what's coming. But for it to be this brand new thing,
- 5:04Speaker 1: he was probably like I bet there was along bike crack. Yeah,
- 5:07Speaker 1: like kids, kids grew up on the Great Space Coaster,
- 5:09Speaker 1: so they know it's coming, you know. Um, But yeah
- 5:12Speaker 1: he said that. Um. He he laid down at home
- 5:16Speaker 1: and UM, these these bizarre but not altogether unpleasant visions
- 5:21Speaker 1: started coming to him and yeah, he was whacked out
- 5:24Speaker 1: for many hours. Um. But we've talked about him before. UM.
- 5:28Speaker 1: A guy who we haven't talked about who I find
- 5:31Speaker 1: just fascinating. His name Santorio Santorio. It's the the researchers
- 5:35Speaker 1: so nice. They named him twice, Sordio Sthordio. Yes, yes,
- 5:39Speaker 1: take a check. Well, he was a self experimenter and
- 5:42Speaker 1: one of the earlier self experimenters. Um, we're talking sixteenth
- 5:46Speaker 1: century style. And uh, what he did is he wanted
- 5:50Speaker 1: to find out about and I guess they didn't call
- 5:53Speaker 1: it metabolism at the time, did they, No, he he
- 5:56Speaker 1: later ending the study. Okay, yeah, back then they had
- 5:59Speaker 1: no I But basically that's what he was doing, was
- 6:01Speaker 1: kind of learning about the human metabolism. And he did
- 6:04Speaker 1: so by h being very meticulous about recording what he
- 6:08Speaker 1: eat eated, what he ate and what he drank, and uh,
- 6:12Speaker 1: weighing his stools and his urine. And I guess he
- 6:17Speaker 1: formed some equation what comes in what goes out? Well,
- 6:20Speaker 1: he found that it doesn't equal. And you you can't
- 6:23Speaker 1: take into account the weight you put on. There's still
- 6:26Speaker 1: some um difference. And he wanted to figure out where
- 6:29Speaker 1: that went. And he came up with the idea of
- 6:31Speaker 1: insensible perspiration, which I thought was going to be all
- 6:35Speaker 1: about sweat. So I was a little disappointed. Well it is, yeah,
- 6:38Speaker 1: but really, I mean it's just like constant, little sweat
- 6:42Speaker 1: weight like that. But the cool thing about Santorio Squared
- 6:45Speaker 1: is that, um, he lived for thirty years chuck essentially
- 6:52Speaker 1: every every day, every every single day for thirty years,
- 6:56Speaker 1: and he basically lived on this machine. It was like
- 6:58Speaker 1: a huge beam scae and he constructed like a little
- 7:02Speaker 1: chair and like a work table and all that. And
- 7:05Speaker 1: he weighed all the food and drink that came on,
- 7:07Speaker 1: and he weighed all the poop and urine that went off.
- 7:10Speaker 1: But he lived on this thing. Well. And what's sad
- 7:12Speaker 1: is that he did all this and it really wasn't
- 7:14Speaker 1: super useful, no, but it opened the doors though for
- 7:17Speaker 1: things like that. It definitely did. And um, one of
- 7:19Speaker 1: one of the other things that did was, um, he
- 7:21Speaker 1: had the idea of insensible perspiration before he did this,
- 7:25Speaker 1: so he was one of the first people to say,
- 7:27Speaker 1: you know what, I'm not just gonna say something. I'm
- 7:30Speaker 1: gonna subject this to scientific rigor. I'm gonna put my
- 7:33Speaker 1: money where my mouth is. I'm gonna scale and weigh
- 7:37Speaker 1: my pooop. Yeah, he's like a stockbroker in the eighties
- 7:41Speaker 1: looking for brand, you know. So that's number one. Uh,
- 7:45Speaker 1: number two, we come to eighteen o three is a
- 7:47Speaker 1: little bit of a jump there to Frederick Wilhelm Adam
- 7:51Speaker 1: Certnir and Um, what he ended up doing was actually
- 7:55Speaker 1: pretty useful for everyone even today, because he did he
- 8:00Speaker 1: discover morphine he isolated did it isolated it from opium? Yeah,
- 8:05Speaker 1: and through two steps got a few friends together. Well,
- 8:09Speaker 1: at first he tested it on animals until they started dying,
- 8:13Speaker 1: sleeping and dying, right, and then he was like, well,
- 8:15Speaker 1: maybe I should try to some people and see what happened.
- 8:17Speaker 1: Because he said, um that animals do not give exact results.
- 8:21Speaker 1: I guess that's true, right, So he and his seventeen
- 8:23Speaker 1: year old friends give exact results. Also, dying is a
- 8:26Speaker 1: pretty exact result. Yeah, So he ouedied a bunch of
- 8:29Speaker 1: animals and he got three uh you pointed out seventeen
- 8:32Speaker 1: year olds plus himself, and I think he was like
- 8:35Speaker 1: twenty at the time he was, so that's like right
- 8:38Speaker 1: in the wheelhouse. Still today, I think he's a middle
- 8:41Speaker 1: age back then though, yeah. Uh. And so he dosed
- 8:44Speaker 1: himself and his friends on a low dose at first,
- 8:46Speaker 1: about a half a grain of morphine, which is thirty mgs.
- 8:51Speaker 1: It's a comparatively low dose to what he took, right,
- 8:54Speaker 1: and that produced a little flushing. He was like, hey,
- 8:56Speaker 1: this is kind of neat, but I'm I'm looking for
- 8:58Speaker 1: more than flushing, so let me take a little more more.
- 9:00Speaker 1: After about fifteen minutes, took a similar dose, started feeling
- 9:04Speaker 1: a little queasy and faint and sleepy, of course, and
- 9:08Speaker 1: to the point where I guess he thought it might
- 9:10Speaker 1: be getting a little dangerous, so he threw up, made
- 9:13Speaker 1: all his friends throw up to get it out of
- 9:16Speaker 1: their system. Well, yeah, he started to get a little
- 9:18Speaker 1: worried that they were all gonna die because they've taken
- 9:21Speaker 1: ninety milligrams of morphine in less than an hour, which
- 9:26Speaker 1: today we realized is ten times recommended us. So yeah,
- 9:30Speaker 1: he he um, he gave everybody like eight ounces of
- 9:33Speaker 1: vinegar to drink and made him throw up and save
- 9:37Speaker 1: their lives. Yeah, imagine they probably huh. Yeah. And then
- 9:41Speaker 1: he did another experiment later because he had a toothache,
- 9:44Speaker 1: and he found that if he just took opium for it,
- 9:46Speaker 1: the toothache wasn't cured, but if he took some morphine
- 9:49Speaker 1: it was cured. Oh, I thought he discovered that by accident,
- 9:52Speaker 1: Like he was like, wait a minute, my toothache. You know,
- 9:54Speaker 1: he kept going, this is the only experiment, Like he
- 9:56Speaker 1: had like many many brushes with death. As far as
- 9:59Speaker 1: self experiment any scientists go, he was probably one of them,
- 10:03Speaker 1: one of the toughest ones, or at least or the
- 10:07Speaker 1: most as the one most addicted to morphine. That's right, Yeah,
- 10:11Speaker 1: but that was a pretty big contribution to humanity. I mean,
- 10:15Speaker 1: that's still like the go to um pain killer today,
- 10:19Speaker 1: I imagine or not imagine, I know this to be true.
- 10:24Speaker 1: Uh up next, Josh, we have Henry Head, Sir Henry Head,
- 10:27Speaker 1: and he got together with his buddy w HR Rivers
- 10:31Speaker 1: and um they this one's a little crazy to meet.
- 10:37Speaker 1: They knew at the time that nerve damage can repair itself,
- 10:41Speaker 1: but what they didn't have was uh documentation, right, because
- 10:46Speaker 1: people couldn't describe it. Good night. They'd be like yeah,
- 10:49Speaker 1: I guess that kind of hurts, yeah, and like yeah,
- 10:51Speaker 1: so what they needed at the time there was no documentation.
- 10:54Speaker 1: So they were like, well, let me cut out a
- 10:55Speaker 1: sliver of my nerve on my arm and sew it
- 10:59Speaker 1: back together. Unless since I can talk about this stuff intelligently,
- 11:03Speaker 1: just I'll do it myself and not just any nerve.
- 11:05Speaker 1: This is a radial that his the radial nerve in
- 11:08Speaker 1: his left arm. Right, he was right handed, which is
- 11:10Speaker 1: why he did this to his left arm because he's no,
- 11:13Speaker 1: he's no dumb right, Um and he had it surgically
- 11:16Speaker 1: removed and the radial nerve, dude goes to the spinal
- 11:20Speaker 1: calm and then all the way down branches all the
- 11:23Speaker 1: way down to the hand, so it's like a major nerve.
- 11:26Speaker 1: And he had a section cut out and then tied
- 11:28Speaker 1: back together with silk and then said, Okay, I'm just
- 11:31Speaker 1: gonna spend the next five years paying attention to how
- 11:33Speaker 1: the um sensation uh semantaception comes back. That's right, and
- 11:39Speaker 1: not only that, chuck. So, dude, I got a root
- 11:42Speaker 1: canal the other day, as you know, he said, it
- 11:44Speaker 1: wasn't too bad. Huh, No, it wasn't. But I was
- 11:48Speaker 1: thinking about Henry Head because while it was going on,
- 11:51Speaker 1: I kind of went off to my happy place. I
- 11:53Speaker 1: just like left my body as much as possible in
- 11:56Speaker 1: case any pain did come along, it would be kind
- 11:59Speaker 1: of muted. What Henry Head did that work? Was it did? Yeah?
- 12:03Speaker 1: You know, like you're not looking for the pain, You're
- 12:05Speaker 1: trying to avoid it mentally. Yeah, and it definitely makes
- 12:08Speaker 1: it worse if you're attention, yes, he But what Henry
- 12:13Speaker 1: Head did was create this kind of trance like state
- 12:16Speaker 1: called negative attitude of attention, where he focused his attention
- 12:22Speaker 1: inward on pain, looking for it, so he could, you know,
- 12:26Speaker 1: I guess, experience it more fully and pay attention to
- 12:29Speaker 1: the type of pain it was. This guy went on
- 12:32Speaker 1: this journey of pain, excruciating pain at times. Yeah. What
- 12:38Speaker 1: was his quote to his wife? He said, I shall
- 12:42Speaker 1: know a great deal about pain by the time this
- 12:44Speaker 1: experiment is over. And he was right, yeah, whatever, But
- 12:48Speaker 1: he was a bad dude. She's like, what's this bringing
- 12:50Speaker 1: in this eternal pain? But he, uh, you know that
- 12:55Speaker 1: documentation was important because they've never been able to describe
- 12:59Speaker 1: for they probably didn't follow patients up like they do now,
- 13:02Speaker 1: you know, like five years later, right, Well, and this
- 13:05Speaker 1: was over the course of five years, so like they
- 13:07Speaker 1: they basically documented how sensation returns after a major nerve damage.
- 13:11Speaker 1: And he also contributed a lot to experimental psychology with
- 13:16Speaker 1: the negative attitude of attention. UM. Basically, there's this whole
- 13:21Speaker 1: thing of reverie where you're just basically zoned out, like
- 13:23Speaker 1: Ralphie in um a Christmas story like that that was
- 13:27Speaker 1: never documented before. And basically what Henry Head did was say, oh,
- 13:31Speaker 1: here's a way to explore that. I don't get the Ralphie.
- 13:34Speaker 1: Remember where they're like Ralphie and he like comes to
- 13:37Speaker 1: remember his his little daydream about getting the A plus
- 13:41Speaker 1: plus plus plus plus. That's Reverie. Yeah, that's good. Family
- 13:46Speaker 1: comedy is number four in our list. Josh, I could
- 13:50Speaker 1: like to call the dude who loved drugs Alexandra Shulgin.
- 13:55Speaker 1: We talked about him before, and he was a chemist
- 13:57Speaker 1: for doll in the sixties. We talked about in the
- 14:00Speaker 1: can Psychedelics treatmental Illness, that's the one he showed up in. Right.
- 14:04Speaker 1: He was basically um toying with with mescaline and and
- 14:08Speaker 1: compounds that later became ecstasy M D M A M
- 14:12Speaker 1: D M A. I have a hard time saying that.
- 14:15Speaker 1: And he and his wife took a lot of these
- 14:17Speaker 1: psychoactive drugs, had parties and the Martini as the usual
- 14:22Speaker 1: method of the sixties, put a little drugs in there,
- 14:25Speaker 1: and uh, you know, that's basically his story. He he
- 14:29Speaker 1: liked the drugs, and I guess he documented all this stuff, right, Yeah,
- 14:33Speaker 1: he went just partying, was he? I don't know if
- 14:36Speaker 1: partying is the right word, But I don't know that
- 14:38Speaker 1: he was always documenting. I don't know if it was
- 14:40Speaker 1: always scientifically rigorous how many did he take here? So
- 14:44Speaker 1: there's like an estimated three hundred psychoactive compounds in the world,
- 14:48Speaker 1: and he estimated that he sampled between two hundred and
- 14:51Speaker 1: two and fifty of them. So he liked the psychedelics
- 14:54Speaker 1: a lot. He put into the dead Simothy Learry to shame,
- 14:59Speaker 1: didn't he They were probably buddies? Was he American? Yeah? Okay,
- 15:04Speaker 1: So let's go back a little bit from the drug
- 15:07Speaker 1: adult sixties to nineteenth century. Yeah, eighteen nineteen, Right, there's
- 15:12Speaker 1: a Czechoslovakian monk who um at age thirty two, became
- 15:18Speaker 1: a doctor because, um, he didn't think that the whole
- 15:23Speaker 1: recommended dosage thing that was being doled out at the
- 15:26Speaker 1: time was he called it nothing but mysticism. He thought
- 15:30Speaker 1: it was way too low and basically, um was homeopathy.
- 15:36Speaker 1: I think he had a problem with homeopathy. His name
- 15:38Speaker 1: is yam Per Kenny, and he uh, he basically said, Okay,
- 15:43Speaker 1: I'm gonna become a doctor so I can learn more
- 15:44Speaker 1: about this, and then I'm gonna take as many drugs
- 15:46Speaker 1: as I can get my hands on, and um overdose
- 15:50Speaker 1: and then pay attention to what happens to me, because
- 15:54Speaker 1: I want to figure out what the recommended dosage should be. Yeah.
- 15:57Speaker 1: The coolest part about this guy's story, I think is
- 16:00Speaker 1: that after he started doing this, like taking things like
- 16:02Speaker 1: fox glove to blur his vision and then writing about
- 16:05Speaker 1: that night shade Ah, the word got out and people.
- 16:10Speaker 1: I got the sense that other doctors were like, Hey,
- 16:12Speaker 1: there's this dude that you'll let you do anything. Do
- 16:15Speaker 1: it right, He'll take anything, So they started doing that. Yeah.
- 16:18Speaker 1: One of his teachers, UM at med school, said Hey,
- 16:22Speaker 1: I've got these three different extracts of epocac, and I
- 16:25Speaker 1: need to find out which one's best. So what do
- 16:27Speaker 1: you think which one? Is there anything that that does
- 16:29Speaker 1: besides make you vomit? Nope, Okay, that's it's sole purpose
- 16:32Speaker 1: as far as I know, that's it. Have you ever
- 16:35Speaker 1: ever heard of it used for anything else? No? I
- 16:36Speaker 1: haven't either. No, I don't ever want to have it,
- 16:38Speaker 1: but um, I want to try it this, so yeah,
- 16:41Speaker 1: PERKINI UM conducted a three week trial of these three
- 16:46Speaker 1: extracts of ipecac, and by the end of the trial,
- 16:49Speaker 1: he'd conditioned like a vomiting response whenever he saw like
- 16:52Speaker 1: a brown powder that looked like iocac. Again, this life's
- 16:57Speaker 1: like you want some cinnamon TOAs well. You know, it's
- 16:59Speaker 1: interest seeing his wife died and he became um in
- 17:03Speaker 1: charge of raising his three boys, and he said, okay,
- 17:06Speaker 1: I'm not a self experimenting anymore. I gotta I have
- 17:08Speaker 1: to stick around and take care of these these jokers. Yeah,
- 17:12Speaker 1: it was pretty cool. He said he was leaving it
- 17:14Speaker 1: to the younger generation. But he's been doing it for
- 17:17Speaker 1: twenty years already. And um, not just ipecac and uh
- 17:21Speaker 1: fox glove, but also um nightshade. We now use atropine,
- 17:26Speaker 1: which is the active ingredient night shade to dilate pupils
- 17:29Speaker 1: thanks to him, because he overdosed on night shade to
- 17:32Speaker 1: find out what would happen. And he would also make
- 17:34Speaker 1: himself very dizzy to study vertigo on carousels. Yeah, there's
- 17:38Speaker 1: the type of vertigo named after him. Yeah, because he
- 17:41Speaker 1: he studied it and figured it out. So he would
- 17:43Speaker 1: just like get on the carousel until it and then
- 17:45Speaker 1: stand up and yeah. But rather than this is a
- 17:49Speaker 1: common thread in in self experimentation, like with my root
- 17:54Speaker 1: canal or if you're dizzy on a carouself, you go inward.
- 17:57Speaker 1: You you you shy away from it. You don't want
- 18:00Speaker 1: to pay attention to any details. You just want everything
- 18:02Speaker 1: to end right with self experimenting researchers do is throw
- 18:06Speaker 1: themselves into the experience and pay attention and gain all
- 18:10Speaker 1: that knowledge from it that you know, any one of
- 18:12Speaker 1: us could do if if we were good at describing
- 18:15Speaker 1: things scientifically, but we don't because we want to avoid
- 18:19Speaker 1: pain and discomfort. Guys did it for us, they did, thankfully. Yeah,
- 18:23Speaker 1: well that's why we're doing this one too. It's like,
- 18:25Speaker 1: hats off to him. If you haven't gotten that impression yet,
- 18:29Speaker 1: thank you, hats off. What if I just did that
- 18:33Speaker 1: and I had like a reversal and I like, you
- 18:37Speaker 1: couldn't say anything about it, all right? George Stratton is next,
- 18:40Speaker 1: and he uh did something a little crazy. You know.
- 18:45Speaker 1: He wore reversing lenses in the nineties. So he learned
- 18:50Speaker 1: that our visual information comes in in an inverted manner.
- 18:54Speaker 1: We all know this, right, well, he knew that, but
- 18:57Speaker 1: there were theories that said this, that's how it has
- 19:01Speaker 1: to be, and he wanted to find out if that
- 19:03Speaker 1: was true, Like, does visual information have to be inverted
- 19:06Speaker 1: for us to see upright? Because you know that it
- 19:09Speaker 1: flips over in the brain exactly right. So can you
- 19:12Speaker 1: imagine what he did to his brain by doing this? Yeah,
- 19:15Speaker 1: it's pretty crazy. He wore these reversing lenses, which basically
- 19:19Speaker 1: presented the visual information right side up, um, and were
- 19:23Speaker 1: them for eight days straight. So it provided it right
- 19:27Speaker 1: side up to the brain. But if we wore that,
- 19:30Speaker 1: everything would look upside down. And he did. He like
- 19:33Speaker 1: you said, eight days straight, unbelievable. He said. The thing
- 19:35Speaker 1: that got him the most was like he would put
- 19:38Speaker 1: his hand out moving right. Well, he had to just
- 19:41Speaker 1: sit there for like the first four days. He couldn't
- 19:43Speaker 1: move at all. Yeah, but um, he would put his
- 19:46Speaker 1: he would stretch his hand out and it would come
- 19:48Speaker 1: in from the top rather than the bottom. He said,
- 19:51Speaker 1: everything was just like a dream. Um, I'd like to
- 19:53Speaker 1: try that out for like a second, you know, I'd
- 19:55Speaker 1: just like to put some on and be like, oh right,
- 19:57Speaker 1: that's weird. Let me take them right back off exact,
- 20:00Speaker 1: not leave them on for eight days. Apparently, by the
- 20:03Speaker 1: fifth day, everything started to um show up as upright again. Yeah,
- 20:08Speaker 1: and then if you really concentrated on it, it would
- 20:10Speaker 1: go back to being upside down. But so did he
- 20:13Speaker 1: rewire his brain? Yeah, he proved that the visual information
- 20:17Speaker 1: doesn't have to be inverted to be seen upright, um,
- 20:21Speaker 1: and that the brain is really capable of adapting in
- 20:24Speaker 1: a fairly short time to basically the most radical changes
- 20:29Speaker 1: in in the stations it is presented. So I guess
- 20:32Speaker 1: that's sort of helped. I mean, it's not like that
- 20:34Speaker 1: led to any huge breakthrough that I think it probably gave. Yeah,
- 20:39Speaker 1: I would think that it probably formed the basis of
- 20:41Speaker 1: like neural plasticity surely, all right. Yeah. Plus also, I mean,
- 20:47Speaker 1: anybody who does that, that's mind bending. You know, he
- 20:51Speaker 1: gets a he gets a pat on the back for that,
- 20:53Speaker 1: no matter what. Well. And he also found too that
- 20:56Speaker 1: after taking them off that it took a little while
- 20:58Speaker 1: to get back to normal, which the process something too
- 21:01Speaker 1: about your brain unlearned and his brain was. Yeah. He
- 21:05Speaker 1: said that he had like glasses at first, and he
- 21:08Speaker 1: said it was just too much. He couldn't do it.
- 21:10Speaker 1: So he blindfold of one eye for eight days and
- 21:14Speaker 1: had like basically a monocle like a little yeah, just
- 21:18Speaker 1: single lens and that's the one he wore for eight days.
- 21:21Speaker 1: He said it was just too much to have two lenses.
- 21:24Speaker 1: So you want to do Carl lon Steiner. Uh yeah,
- 21:28Speaker 1: he he actually did do a lot of good work.
- 21:30Speaker 1: He was Viennese and he was a physician, and he
- 21:35Speaker 1: basically came up with the blood typing system, the A
- 21:38Speaker 1: B O blood typing system, because he noticed that red
- 21:41Speaker 1: blood cells and some people clump in the presence of
- 21:45Speaker 1: the fluid component, which is serum, but not everybody. So
- 21:47Speaker 1: we thought it's almost as if their blood is a
- 21:51Speaker 1: different type from one another. Well, at the time, like
- 21:53Speaker 1: they knew that that would happen because you give people
- 21:55Speaker 1: blood transfusions and then they die and um they because
- 22:00Speaker 1: BO was clumped. Yeah, but at the time everybody thought
- 22:03Speaker 1: it was because those people had some unknown disease. And
- 22:05Speaker 1: lon Steiner was like, I think that people just have
- 22:08Speaker 1: different types of blood. So he used his own blood
- 22:11Speaker 1: in some of his colleagues, we should do one on
- 22:13Speaker 1: blood type. I think we should. Is that true? Like
- 22:15Speaker 1: your body cannot literally cannot accept another blood type. It
- 22:19Speaker 1: depends I think, oh is the universal type, so you
- 22:22Speaker 1: can um except but if you have like A can
- 22:25Speaker 1: you can't have B at all because the red blood
- 22:27Speaker 1: cells clump and your blood doesn't flow and you die.
- 22:31Speaker 1: So it's like putting diesel in a very much in
- 22:33Speaker 1: a regular very much. So yeah, um so what like
- 22:36Speaker 1: you said, what Lon Steiner did was a huge contribution
- 22:40Speaker 1: because he showed, you know, there's different anigens in different
- 22:44Speaker 1: types of blood, and that creates this different blood type
- 22:47Speaker 1: a bo or a b um. And when you when
- 22:52Speaker 1: you if you tell if you test people first and
- 22:55Speaker 1: say oh, they're a type and we've got some a
- 22:58Speaker 1: type blood over here, a blood transfusion will work, and
- 23:00Speaker 1: so will oregan donation and all the other huge. Yeah,
- 23:03Speaker 1: it was enormous. I bet doctors were like, oh, well
- 23:06Speaker 1: that's good to know in these people. Um. So yeah
- 23:12Speaker 1: he won the Nobel Prize in ninety that rightly, so yeah,
- 23:15Speaker 1: he should win it every year. But what's crazy is
- 23:18Speaker 1: you know he he just he experimented on himself. It's
- 23:21Speaker 1: kind of cool. Um. But what's nuts is that he
- 23:25Speaker 1: also uses colleagues blood. And it just so happened that
- 23:28Speaker 1: out of like five people, they all had different blood types,
- 23:32Speaker 1: like types were present. It could have gone the exact
- 23:35Speaker 1: opposite way and just everybody had a type and then
- 23:38Speaker 1: he said no, they're the same, yeah exactly. So I
- 23:41Speaker 1: thought that was pretty cool and it was almost providence
- 23:44Speaker 1: well and he he led that led to Dr Jack
- 23:47Speaker 1: Goldstein UM in the nineteen eighties to do He was
- 23:51Speaker 1: a biochemist that did more experimenting and this one confused
- 23:54Speaker 1: not confused me. But he found out that an enzyme
- 23:57Speaker 1: and coffee, when injected into BE blood removes anigin and
- 24:01Speaker 1: basically makes it the universal blood type. How did he
- 24:03Speaker 1: figure that out? I don't know. The coffee, I don't know,
- 24:06Speaker 1: but he figured it out. But I just injected coffee
- 24:10Speaker 1: one day to see what that would do and in
- 24:12Speaker 1: my blood. Right, So he he had O type blood,
- 24:15Speaker 1: so that that this enzyme changes B type blood O
- 24:18Speaker 1: type blood. UM, and he had O type blood. So
- 24:21Speaker 1: to prove that this worked, he got a blood transfusion
- 24:24Speaker 1: of this treated B blood that was ostensibly now OH blood.
- 24:28Speaker 1: So he got a blood transfusion, a small one, but
- 24:31Speaker 1: he did it himself, UM to see if you know,
- 24:34Speaker 1: his arm would fall off or something like that, or
- 24:36Speaker 1: if his blood would clump. And it worked. And it's
- 24:39Speaker 1: still being worked out. But apparently, UM, you know that
- 24:43Speaker 1: opens up like the donation pool. If you can just
- 24:46Speaker 1: take all this B type blood and you need OH,
- 24:49Speaker 1: which is the universal type. Just injected with this enzyme,
- 24:52Speaker 1: and I wonder how much blood you have to have
- 24:55Speaker 1: transfused before it, Like how much diesel can you put
- 24:59Speaker 1: in there? I don't know, Like if you if they
- 25:01Speaker 1: just did like a vial with that, like what would
- 25:03Speaker 1: that do to your body? I don't know, because Goldstein
- 25:06Speaker 1: did like eleven billion, eleven and a half billion red
- 25:09Speaker 1: blood cells, and I don't know if that's just a
- 25:12Speaker 1: few drops or if that's like half a pine or
- 25:14Speaker 1: a pine or what. Yeah, well we'll have to find
- 25:18Speaker 1: that out in the blood typing episode. Okay, well I
- 25:20Speaker 1: have I've been wanting to do the blood one for
- 25:23Speaker 1: a while, but it's just like, let's do it right now.
- 25:25Speaker 1: It's tough. I'm gonna need a little while on that one. Okay, Okay,
- 25:29Speaker 1: do we have a blood typing article? Well, we have
- 25:31Speaker 1: an article on blood that's like really dense. Oh yes,
- 25:34Speaker 1: we started to do that when we're like, yeah, we're
- 25:37Speaker 1: not doing this right now. It was I thought I
- 25:39Speaker 1: think it was written by an M. D. Wasn't it.
- 25:42Speaker 1: It read like it. Yeah, So look for the revised
- 25:45Speaker 1: version coming in the future. All right. I like number
- 25:48Speaker 1: nine Erman is it Herman or Erman Ebbing? House. I
- 25:54Speaker 1: don't think he's Portuguese. He was a German. Would Airman Portuguese? Yeah, Erman,
- 26:00Speaker 1: I don't know he's Herman. Then let's just call him Herman.
- 26:02Speaker 1: He was German. And uh he was the first guy
- 26:06Speaker 1: to really study memory and a really maybe at all,
- 26:09Speaker 1: but in a really scientific way, which was which was
- 26:13Speaker 1: unusual at the time to apply scientific research principles to
- 26:17Speaker 1: psychological matters. Right that it was like basically taking the
- 26:20Speaker 1: way the hard science is doing and applying it to
- 26:23Speaker 1: the soft science of psychologists. But he formed the methodology
- 26:27Speaker 1: that's still in use today and proved that it can work. Like, yes,
- 26:31Speaker 1: you can study you know, cognitive faculties like memory in
- 26:36Speaker 1: a science way, in a science way, science e way. Um,
- 26:39Speaker 1: so what he did was pretty cool. He created Uh,
- 26:43Speaker 1: the first thing he did was he created these non
- 26:45Speaker 1: syllable nonsense syllable of them with two consonants with a
- 26:50Speaker 1: vowel in the middle, like nog this is one example
- 26:53Speaker 1: you used. And he had to make them nonsense because
- 26:57Speaker 1: there had to be like no so ciation with like
- 27:01Speaker 1: previous words that he had learned that had to be
- 27:03Speaker 1: brand new things in his brain because I mean, if
- 27:07Speaker 1: you if you have a previous association with a syllable,
- 27:11Speaker 1: right like SKay. Okay, and you have a great memory
- 27:15Speaker 1: of ice skating as a child, and SKay brings that
- 27:18Speaker 1: to mind. Of course you can remember SKay. I'm surprised
- 27:21Speaker 1: he came up with I would that'd be tough for me. Uh.
- 27:26Speaker 1: So what he did was he basically, over the course
- 27:30Speaker 1: of a year, uh learned these words and then to
- 27:35Speaker 1: the point where he could recall them perfectly, and then
- 27:37Speaker 1: recorded how long it took for him basically to forget
- 27:41Speaker 1: them and then relearn them again. And that taught us
- 27:44Speaker 1: all sorts of cool things about memory. Yeah. He he
- 27:46Speaker 1: figured out that um and a lot of this stuff
- 27:49Speaker 1: you know is so commonplace. We we know it, we
- 27:52Speaker 1: take it very much for granted. But this guy is
- 27:54Speaker 1: the one who figured out that UM, meaningless stuff is
- 27:58Speaker 1: harder to learn than meaning full stuff. Um. He gave
- 28:02Speaker 1: us the idea of the learning curve. The more stuff
- 28:05Speaker 1: you have to learn, the longer it's going to take
- 28:07Speaker 1: to learn it. Yeah. I think he was the first
- 28:09Speaker 1: person actually name it to the learning curve. I think
- 28:11Speaker 1: so it's possible. I believe so Okay, um and uh
- 28:16Speaker 1: forgetting happens most rapidly right after learning and then kind
- 28:19Speaker 1: of evens off and slows down. Um. And he taught
- 28:23Speaker 1: us that cramming doesn't work, that learning is best when
- 28:28Speaker 1: it's done over a longer time than you know, a
- 28:31Speaker 1: single Yeah, because boy, I used to cram pretty well.
- 28:37Speaker 1: Did you stunk at it? I was good at it?
- 28:40Speaker 1: I was not. I just I would just be too
- 28:42Speaker 1: stressed out. Well, and I short changed myself though, because
- 28:45Speaker 1: I would do well in the test and then forget it,
- 28:49Speaker 1: which was I mean, I wasn't doing myself any favors
- 28:51Speaker 1: as far as gaining knowledge. You know, I took Italian
- 28:54Speaker 1: um in college, and it was the only language that's
- 28:58Speaker 1: ever clicked for me, Like I got a town in
- 29:00Speaker 1: on a fundamental level. Yeah, and just aced the class
- 29:04Speaker 1: until the final, and I studied for the final. I
- 29:06Speaker 1: don't think I crammed it, just you know, I didn't
- 29:08Speaker 1: take it for granted that I was gonna ace the final.
- 29:11Speaker 1: But I for some reason I got there and forgot
- 29:15Speaker 1: everything when I sat down, and well then I panicked, Yeah,
- 29:19Speaker 1: but it wasn't panic until I realized that I had
- 29:21Speaker 1: forgotten everything. And I still did this day. Don't understand
- 29:24Speaker 1: what happened, and I don't remember. It's not like it
- 29:26Speaker 1: came back after the test. It just went away right
- 29:30Speaker 1: before the final. You know what happened? What Centorio Sordio,
- 29:34Speaker 1: That's what happened. I started, I started weighing my feces,
- 29:37Speaker 1: and it chased away all my understanding of battalion, and
- 29:41Speaker 1: I stopped after one trial. Did you? I'm just saying,
- 29:46Speaker 1: I've waited my feces once, and I know you gotta
- 29:48Speaker 1: do it more than once. He also created the ebbing
- 29:51Speaker 1: House illusion. Have you ever heard that? That's that thing?
- 29:54Speaker 1: Right there? Is that the same size that is not
- 29:58Speaker 1: the same size, It is not the same side. It's
- 30:02Speaker 1: a very famous illusion where there are two same sized circles,
- 30:06Speaker 1: they're not the same size. And then the one on
- 30:08Speaker 1: the left has these very large circles around it and
- 30:10Speaker 1: the one on the right has very small circles around it,
- 30:13Speaker 1: and it gives the appearance that they're different sizes, but
- 30:16Speaker 1: they are not so. Eving House is a pioneer in
- 30:18Speaker 1: experimental psychology, which is pretty cool, absolutely, and in experimental
- 30:24Speaker 1: psychology still today. Self experimentation is um fairly commonly used
- 30:31Speaker 1: UM because it's not nearly as dangerous as it is
- 30:33Speaker 1: in say medicine. For that reason, science today is basically
- 30:38Speaker 1: like you can't self experiment. That's so nineteenth century. Well,
- 30:43Speaker 1: and beyond the dangers of it, there's something called double
- 30:47Speaker 1: blinds and placebos that you know, if you know, if
- 30:50Speaker 1: you're self experimenting, then there that's going to affect the
- 30:53Speaker 1: outcome of the experiment almost time with the double blind
- 30:58Speaker 1: is like a hallmark of science, the inquiry, and you
- 31:01Speaker 1: it's impossible with when you're experimenting on yourself. So, uh,
- 31:07Speaker 1: if you're looking for grant funding and you're saying, well,
- 31:10Speaker 1: I'm just gonna try this drug on myself and see
- 31:12Speaker 1: what happens, You're not gonna get that funding, but probably
- 31:15Speaker 1: won't get published either, right, Well, it depends. There's this
- 31:18Speaker 1: guy named Seth Roberts who published a paper about his
- 31:21Speaker 1: twelve years of self experimentation. And he's a psychologist, um,
- 31:25Speaker 1: but the paper that he published was about the self
- 31:28Speaker 1: experimenting he did in his spare time. So if you're
- 31:31Speaker 1: not an experimental psychologist, um, probably if you're into self experimentation,
- 31:36Speaker 1: you're either um some sort of pro scientist doing it
- 31:39Speaker 1: in your spare time, or you're an amateur. There's a
- 31:42Speaker 1: there's a been a movement called an equals one, which
- 31:47Speaker 1: is you know, in his scientific notation for the study
- 31:50Speaker 1: sample size or population size, didn't called quantified self though.
- 31:53Speaker 1: That's a movement. Well, that's the um, that's the website.
- 31:56Speaker 1: There's like a group where it's kind of like this
- 31:58Speaker 1: hub of like, hey, I want to figure out why
- 32:01Speaker 1: I had migraine. So I started tracking like my food
- 32:04Speaker 1: and they were wired editors. I think, yeah, yeah, I
- 32:09Speaker 1: did not know that. Yeah, yeah, So there's a quantified self.
- 32:12Speaker 1: Dot com is basically this awesome place where you can
- 32:15Speaker 1: go see how other people are carrying out their own
- 32:17Speaker 1: self experiments and gets a little wacky. Yeah, there's just
- 32:20Speaker 1: one lady that drinks her first yurine of the day
- 32:23Speaker 1: each day she records all that. Are you sure you
- 32:28Speaker 1: saw that? I read it. I didn't see her do that. Well,
- 32:32Speaker 1: but he didn't click on the YouTube. Know, there's all sorts.
- 32:35Speaker 1: There was a big Forbes. Forbes had a big article
- 32:38Speaker 1: on this movement, which is some people call it naval
- 32:42Speaker 1: gazing at its finest. Other people think it's valid. Well
- 32:46Speaker 1: that's the point that Seth Roberts made. He was saying like,
- 32:49Speaker 1: I don't need funding for this because I'm just doing
- 32:51Speaker 1: it my spare time. It costs like basically no money.
- 32:54Speaker 1: Get off my back. I just pay attention. But he
- 32:56Speaker 1: also said that, um, he was motivated. He had the
- 32:59Speaker 1: motivation of a person looking to solve a problem, like
- 33:02Speaker 1: he wanted to control his weight or mood or make
- 33:06Speaker 1: himself a happier person, um, get better sleep. So he
- 33:10Speaker 1: just carried out all these self experiments and he could
- 33:13Speaker 1: conduct more than one at a time. So yeah, he
- 33:16Speaker 1: was like, get off my back. I think it's kind
- 33:18Speaker 1: of cool though, Like I have lactose issues and I
- 33:20Speaker 1: could see myself getting into um eating to tracking that
- 33:26Speaker 1: and and isolating exactly which foods. I mean, that's basically
- 33:29Speaker 1: all it is. That's it's kind of cool. And drinking
- 33:31Speaker 1: your own urine type will draw the line there. So, UM,
- 33:35Speaker 1: we should probably say thanks to some of the sources
- 33:39Speaker 1: that helped us with this podcast Clark Oscillatory Thoughts Blog. Um,
- 33:46Speaker 1: let's see Tiffany Watt Smith wrote Henry Head in the
- 33:49Speaker 1: theater of Reverie. Scientific American had a cool article self
- 33:52Speaker 1: experiment and step up for science. Alan Neringer had a
- 33:55Speaker 1: paper from one called self experimentation a call for change.
- 33:59Speaker 1: Lawrence kay Altman literally wrote the book on this. Um
- 34:02Speaker 1: who goes First? The Story of Self Experimentation in Medicine? Yeah, exactly.
- 34:07Speaker 1: Um A. Cohen wrote an article in the British Journal
- 34:11Speaker 1: of Clinical Pharmacology about UM Sara Turner's experiments. He in
- 34:15Speaker 1: his good Time Buddies. Um Salvatore Kurri did he rideout sad?
- 34:21Speaker 1: He wrote about George Stratton. Uh, the University of Indiana
- 34:25Speaker 1: has a cool human intelligence department quantified self dot com.
- 34:28Speaker 1: If you want to get into self experimentation and don't
- 34:30Speaker 1: feel like suing us for mentioning it, it's interesting to
- 34:33Speaker 1: look at at the very least. Yeah, I agreed, and
- 34:35Speaker 1: then Seth roberts the unreasonable effectiveness of my self experimentation
- 34:39Speaker 1: is the name of the paper. So those are all
- 34:41Speaker 1: the ones, and then pretty soon there'll be a list
- 34:44Speaker 1: top ten list on the site. It's not published yet,
- 34:48Speaker 1: it's practically done. I would assume, and Chuck, if you
- 34:51Speaker 1: forgot the name of the show that we were promoting
- 34:57Speaker 1: on sign channel, why don't we do a little ad
- 34:59Speaker 1: for it? That's true? Yeah, um chuck. A couple more
- 35:02Speaker 1: shout outs are good, good friend Wyatt Senak. Yes, his
- 35:06Speaker 1: stand up special Wyatt Sanak Comedy Person is out on DVD,
- 35:10Speaker 1: very funny stuff and if you've only seen why it
- 35:13Speaker 1: on the Daily Show he is. Uh, he's great on
- 35:16Speaker 1: the Daily Show. But his stand up is hysterical and
- 35:19Speaker 1: different than you would think it would be. It is.
- 35:22Speaker 1: He's much more like lively and animated and he's awesome.
- 35:25Speaker 1: He's a good guy too. Um. And we have a
- 35:28Speaker 1: happiness audio book out, that's right, the Grammy nominated nominated
- 35:33Speaker 1: Happiness Audio book, The super Stuff Guide to Happiness. That's right. Um,
- 35:37Speaker 1: it's up on iTunes for three nine nine. You're gonna
- 35:39Speaker 1: end up selling out more if you're in Australia. We're sorry.
- 35:42Speaker 1: Um let's see what else. Oh, it's got all sorts
- 35:46Speaker 1: of great sound design interviews. It's just cool. We've got
- 35:49Speaker 1: some experts on the horn. Ye, my niece, yes, starts
- 35:53Speaker 1: it out. Um and uh, yeah, it's up on iTunes.
- 35:57Speaker 1: Just search for super Stuff Guide to Happiness and that
- 35:59Speaker 1: will also bring up, um, the super Stuff Guide to
- 36:03Speaker 1: the Economy, which is still evergreen and good. Are we
- 36:05Speaker 1: gonna do any more of those? I think we should
- 36:08Speaker 1: just I mean I would feel like I just we
- 36:11Speaker 1: should okay, we would it feel like a quitter if
- 36:13Speaker 1: we just had to. Yeah, we need at least three.
- 36:16Speaker 1: I would like four at least okay, okay, and then
- 36:19Speaker 1: one more administrative detail. We have a cool little thing.
- 36:22Speaker 1: If you text um s y s K to eight
- 36:26Speaker 1: zero five six five, it texts you back a link
- 36:31Speaker 1: to listen to the podcast on your iPhone without going
- 36:34Speaker 1: through iTunes if you're not in the mood. Is that
- 36:36Speaker 1: what it did? Yeah, it's cool. It brings up our
- 36:39Speaker 1: r S speed and you can just listen to it.
- 36:41Speaker 1: I think it's quick time, so it'll work on your
- 36:43Speaker 1: iPhone or your droid or whatever. That's our latest marketing invention. Yeah,
- 36:48Speaker 1: it's pretty cool. So UM just text s y s
- 36:50Speaker 1: K two eight oh five six five. If you ever
- 36:53Speaker 1: are having a stuff, you should know Jones. It's right.
- 36:58Speaker 1: Friedrich's turners not around. Yeah. By the way, we're we're
- 37:01Speaker 1: working on there's been some issues with the apps, I
- 37:03Speaker 1: think refreshing the podcast less lately, and we are working
- 37:06Speaker 1: Our tech department is working on that. So keep your
- 37:09Speaker 1: pants on, as they say, so this will be up eventually.
- 37:12Speaker 1: You can look for UM ten ten scientists who were
- 37:17Speaker 1: their own guinea pigs love it. In the search bar
- 37:20Speaker 1: at how stuff works dot com, you can also type
- 37:22Speaker 1: in human experimentation and five crazy government experiments and they'll
- 37:26Speaker 1: bring up those articles. Um, and I said, handy search
- 37:30Speaker 1: bar finally somewhere in there, which means it's time. We're
- 37:33Speaker 1: a listener, man, Josh, I'm gonna call this, uh well,
- 37:40Speaker 1: first of all, quickly, if you're from Berkeley, California and
- 37:42Speaker 1: you went to UC Berkeley, we had a slight slip
- 37:46Speaker 1: of the tongue. Seriously, we said, U C l A Berkeley.
- 37:49Speaker 1: We know it's UC Berkeley, we know you see l
- 37:51Speaker 1: A is in Los Angeles. Yes, it was just a
- 37:54Speaker 1: little slip of the dog. That's it. We're not dummies.
- 37:57Speaker 1: And sometimes if you live in or have been to Netterling, Colorado,
- 38:02Speaker 1: and are a fan of the Frozen Dead Guy Days
- 38:04Speaker 1: and are mad we didn't bring it up in our
- 38:05Speaker 1: Cryonics episode, go listen to ten odd town Festivals. It's
- 38:09Speaker 1: in there. It's in there, all right. So back to
- 38:11Speaker 1: the listener mail. This is from Stephen H. And this
- 38:13Speaker 1: was just cool information. I'm a huge fan of the show. Guys,
- 38:17Speaker 1: loved the depth and breadth of the presentations. I'm not
- 38:20Speaker 1: sure how far I uh I am from this week.
- 38:23Speaker 1: He's pretty far, but I just listened to the Black
- 38:26Speaker 1: Death episode. I thought you might be interested to know.
- 38:29Speaker 1: While the plague was a horrible affair with millions of
- 38:31Speaker 1: deaths and an interesting effect on our language today, many
- 38:34Speaker 1: scholars of the history of the English language, myself included,
- 38:38Speaker 1: hold that the plague in England is a major reason
- 38:40Speaker 1: why we write in English today. You see, after the Normans,
- 38:45Speaker 1: which were French vikings, took England at the Battle of
- 38:48Speaker 1: Hastings in ten sixty six, Anglo Norman, French and Latin
- 38:53Speaker 1: became the two major languages of administration and literature because
- 38:57Speaker 1: all the important rich folks were chum. However, for reasons unknown,
- 39:03Speaker 1: the plague seems to have hit the mid range nobility
- 39:06Speaker 1: harder than other groups, resulting in a desperate need for administrators.
- 39:10Speaker 1: The only people left to fill the jobs were regular
- 39:13Speaker 1: joe's who only spoke English. So the theory goes, because
- 39:16Speaker 1: of the plague, the nobility was forced to learn English
- 39:19Speaker 1: to communicate with their administrators, resulting in the re emergence
- 39:23Speaker 1: of English as the language of law, administration, and literature
- 39:27Speaker 1: from Stephen h pretty neto. Yeah, I love supplemental information.
- 39:32Speaker 1: That's those are my favorite ones. So thanks a lot,
- 39:35Speaker 1: Stephen h um and since chucks such a big fan
- 39:38Speaker 1: of supplemental information. UM, if you have any supplemental information
- 39:43Speaker 1: about experimentation, specifically self experimentation, we want to hear it. Yeah,
- 39:48Speaker 1: if you've done this yourself, I'd like to hear about it. Yeah,
- 39:51Speaker 1: but don't do it yourself just to tell us about it, No,
- 39:53Speaker 1: because we don't want even get hurt. That seems like
- 39:55Speaker 1: in the gray area that I'm not comfortable with it.
- 39:57Speaker 1: If you've done like your own lactose study on yourself,
- 39:59Speaker 1: something like that, sure, something harmless, Yeah, like you didn't
- 40:03Speaker 1: inject lactose. Um. You can tweet to us at s
- 40:07Speaker 1: y s K podcast UM. You can go onto Facebook
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- 40:14Speaker 1: or you can send us a plain old fashioned email
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- 40:25Speaker 1: sure to check out our new video podcast, Stuff from
- 40:28Speaker 1: the Future. Join how Stuff Work staff as we explore
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