Episode 38: Your Tamoxifen Dose Is Too High — And a Clinical Trial Proved It
"The majority of cancer drugs are registered at the dose which is intolerable for the majority of women. It causes a lot of clinical and financial toxicity."
Dr. Andrea De Censi has spent his career asking one question: what's the lowest dose that still works? His answer to that question changed how tamoxifen is prescribed—and now he's testing whether a common diabetes drug combined with skipping breakfast could make cancer treatment more effective. He joins Joelle to share what decades of prevention research has taught him, and why so much of it never reaches patients.
They dive deep into…
The skinny
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