Latest / Becker’s Healthcare Podcast / Luis Compres-Brugal, MD, Director of the Neuroimmunology and Multiple Sclerosis Program at the Baptist Health Miami Neuroscience Institute, part of Baptist Health South Florida
Transcript
- 0:00This is Laura Dierda with the Becker's Healthcare
- 0:02Podcast.
- 0:03I'm thrilled today to be joined by doctor
- 0:05Luis Compress, director of neuroimmunology
- 0:08and multiple sclerosis program at Baptist Health Miami
- 0:11Neuroscience Institute, part of Baptist Health South Florida.
- 0:14Doctor Compress, it's a pleasure to have you
- 0:16on the podcast today.
- 0:18Thank you for having me.
- 0:20Absolutely. Now I'm excited to get into our
- 0:21discussion. I know we're gonna be talking a
- 0:23lot about
- 0:24multiple sclerosis and and just the way it's
- 0:31treatments moving forward. But before we do, can
- 0:34you tell us a little bit more about
- 0:35yourself and your background?
- 0:37Yeah. Of course. Well, I was,
- 0:40born and raised in Dominican Republic, and I
- 0:42did my neurology residency in University of Cincinnati,
- 0:47Ohio.
- 0:48After that, I did
- 0:50a fellowship in multiple sclerosis and neuroimmunology
- 0:53at the University of South Florida in Tampa.
- 0:57And, I've been, working here in Baptist since
- 1:00then.
- 1:03That's fantastic. And, you know, really a a
- 1:06a great pathway into a a very important
- 1:09service that you're providing to the community. Now
- 1:11for listeners who may not know much about
- 1:13multiple sclerosis,
- 1:15what exactly is MS, and how does it
- 1:17affect the body?
- 1:19Yeah.
- 1:21Basically, how I explain a very simple way
- 1:24is that when your immune system there is
- 1:27a glitch in your immune system. And instead
- 1:30of fighting viruses and bacteria,
- 1:32it start creating pockets of inflammation
- 1:35in different parts of the brain and the
- 1:37spinal cord,
- 1:39in the optic nerve.
- 1:40And depends on where the symptoms are,
- 1:43or the lesion,
- 1:45is, you can have symptoms.
- 1:51Got it. That makes a lot of sense,
- 1:53and it is helpful to understand kind of
- 1:55where it's coming from and, just the way
- 1:57it impacts a patient's body. Now I I'm
- 2:00curious. When you think about the disease progression,
- 2:04how does it continue to,
- 2:06impact patients,
- 2:08and and what are some early warning signs
- 2:10or symptoms that MS
- 2:12people,
- 2:13who who have it should not ignore?
- 2:16Yeah.
- 2:18Well,
- 2:19people that have MS and they don't know
- 2:22they have MS,
- 2:23and that's a very common question. What are
- 2:25the symptoms?
- 2:26And I divide it in nonspecific.
- 2:29Sometimes it can be fatigue,
- 2:31numbness here and there,
- 2:34brain fog.
- 2:35But more specific
- 2:36MS symptoms are
- 2:38neurological
- 2:40that last more than one day, and it
- 2:42can be
- 2:43weakness or numbness in one side of the
- 2:46body
- 2:47nonstop
- 2:48or
- 2:48vision loss in one eye.
- 2:51It can be double vision for,
- 2:54like I mentioned,
- 2:56before, for a few days.
- 2:58But it varies a lot because it really
- 3:01depends on where the lesion is, where there
- 3:04is a pocket of inflammation
- 3:06that can cause symptoms.
- 3:11Some people may dismiss them as just being
- 3:14normal.
- 3:15It's just
- 3:16let us try to figure that out. That's
- 3:18a message I always try to transmit to
- 3:21patient.
- 3:24Got it. That's helpful to understand.
- 3:26So really looking for some of those,
- 3:29key symptoms and and keeping an eye out
- 3:31for them. And I can imagine it's important
- 3:33to,
- 3:34identify them quickly and find a treatment pathway.
- 3:38Correct.
- 3:39And and and that's very important that you
- 3:41mentioned that because the sooner we diagnose MS,
- 3:44the sooner we can treat it. And the
- 3:46sooner we treat it, we know that those
- 3:48patients long term, they tend to do better.
- 3:51That's helpful to understand. I'm curious, you know,
- 3:54now that we know the early warning signs
- 3:56that patients must pay attention to, I I
- 3:59know for physicians and clinicians, MS can look
- 4:01different from patient to patient. So why can
- 4:04it sometimes be difficult to diagnose,
- 4:06and and what should physicians know about,
- 4:09seeing patients who might present with some of
- 4:10these symptoms or trying to figure out what
- 4:12exactly is going on with them?
- 4:15Yeah. It can be very challenging to diagnose,
- 4:18and the reason is we don't have a
- 4:20specific test that we can get and say,
- 4:23yes. You have MS.
- 4:25It's not as
- 4:26simple as, for example, diabetes or looking at
- 4:29the cholesterol.
- 4:30You just get a a blood test, and
- 4:32you just see those results. With MS, it's
- 4:34like building a puzzle.
- 4:36And we put
- 4:37different pieces,
- 4:39together in trying to come up with a
- 4:41diagnosis.
- 4:42And one of those is, the exam that
- 4:44we do to the patient, what the patient
- 4:46is telling us, MRIs.
- 4:49Sometimes we didn't need lumbar puncture. So once
- 4:51we get all that information, we can, say,
- 4:54okay. This
- 4:56is MS.
- 4:57MRI is the most,
- 5:00important
- 5:01tool that we use.
- 5:03For doctors and primary care physicians and,
- 5:07my message is if there's a patient with
- 5:09new neurological
- 5:10symptom,
- 5:11that has been persistent, especially,
- 5:14it's not wrong to start screening, like, with
- 5:17an MRI of the brain or refer to
- 5:19neurology, and, we can try to figure out
- 5:22either is this MS
- 5:24or is this something else?
- 5:29Got it. That makes a lot of sense,
- 5:31and it's really helpful to think through all
- 5:33the different possibilities, but then making sure you're,
- 5:37finding that that,
- 5:38important screening so, you know, you you can
- 5:41identify early as needed. What are some of
- 5:43the treatment options available today, and how have
- 5:46advances in care
- 5:48improved the quality of life for people living
- 5:50with MS?
- 5:52We have now more than 20 different therapies
- 5:55that we can treat,
- 5:56MS. And over the past ten years, it
- 6:00has been an explosion.
- 6:02We have very effective
- 6:05medicine that can stop relapses or
- 6:08new pockets of lesions,
- 6:10to form.
- 6:11And,
- 6:13now we are working on trying to
- 6:15tackle the part of what we call progression,
- 6:18that slow worsening that occurs over time. And
- 6:22we are the field is moving in that
- 6:24way, and,
- 6:26I'm very positive about that.
- 6:28But besides those,
- 6:31all the medicines that we have for MS
- 6:33is aggressive symptomatic control, trying to have the
- 6:36patient,
- 6:37the best quality of life, treat
- 6:40all their symptoms, and,
- 6:42and other comorbidities
- 6:44as well
- 6:46or other diseases or conditions.
- 6:49That's so important. And, you know, every patient,
- 6:52again, comes with a different,
- 6:54a different condition or different things that they're
- 6:57dealing with in addition to the MS, which
- 6:59makes it so important to have all of
- 7:01those
- 7:02collaborate collaborative view of,
- 7:04their treatments and what's gonna be most beneficial
- 7:07for them. I know it's,
- 7:09MS awareness month. And so during this month,
- 7:12what is the most important message that you
- 7:14want people living with MS and their loved
- 7:16ones to hear?
- 7:19That the future is bright and positive.
- 7:23We are learning
- 7:25more about
- 7:26what MS,
- 7:28how it how how it behaves in the
- 7:30body, understanding the disease better. And by doing
- 7:33that, we can develop better treatment options.
- 7:37Our field is moving towards being more precise,
- 7:40not only diagnosing and treating,
- 7:43but also managing,
- 7:44these patients,
- 7:45long term. There's a lot of exciting research
- 7:48that,
- 7:49is under development and coming out.
- 7:54That's cool to hear and especially important for
- 7:56those who are living with the disease.
- 7:58And
- 7:59looking at some of the the cool innovations
- 8:03in,
- 8:04a bright and and positive future is so
- 8:06helpful. Could you tell us about the work
- 8:08being done at Miami Neuroscience Institute to care
- 8:11for patients with MS and how that's making
- 8:13a difference for people in the community?
- 8:17Yeah. So, thank you.
- 8:20What we try to achieve and what we
- 8:22have been doing is,
- 8:24do a comprehensive care for these patients.
- 8:27They don't not only need the neurologist.
- 8:30Yes. We are important in the patient's, care,
- 8:33but all their disciplines, meaning all their providers,
- 8:37let's say, urologist when they have urinary symptoms,
- 8:41psychiatrist,
- 8:42we know that, depression is really common in
- 8:45the multiple sclerosis,
- 8:47rehab, physical therapy, occupational therapy.
- 8:51Those are some of the things that we
- 8:53can offer.
- 8:54When it comes to treatment. We do have
- 8:57infusion centers.
- 8:58Some of the medicines for MS, they are
- 9:01through the veins, and we can do that
- 9:03for these patients.
- 9:05And research. We are,
- 9:07working on some research,
- 9:09projects that patient can be involved,
- 9:12and can benefit from all these exciting new
- 9:15therapies that are coming out.
- 9:19I love that. Doctor Compress, thank you so
- 9:21much for joining us on the podcast today.
- 9:23This has been a really fantastic discussion, uplifting,
- 9:27especially for a challenging topic. So I appreciate
- 9:29your time today and look forward to continuing
- 9:31the conversation soon.
- 9:33Thank you, Laura. It was great.