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The Urine Revolution: How a Pregnancy Hormone Remade Medicine
The Urine Revolution: How a Pregnancy Hormone Remade Medicine
Pregnant urine yielded a crystalline estrogen in 1929 that was being injected into women within months - and that molecule, estrone, became one of the most prescribed hormones of the twentieth century. How did estrone go from urine to worldwide pharmaceutical industry before anyone fully understood its biology?
In this episode, we tell the story of how estrone moved from laboratory isolation to rapid commercial use across multiple companies and formulations, and why clinicians began using it for menopausal symptoms, hypogonadism…
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