Latest / Becker’s Healthcare Podcast / Advancing Pediatric Diagnostics Through Strategic Partnerships and Innovation
Transcript
- 0:00Hello, everyone. This is Erica Spicer Mason with
- 0:02Becker's Healthcare. Thank you so much for tuning
- 0:04into the Becker's Healthcare podcast series.
- 0:07Today, we're going to talk about a special
- 0:09partnership between CHOP and LabCorp.
- 0:11And joining me for this conversation, we have
- 0:13with us three guests. We have doctor Steven
- 0:16Master, vice chair for innovation, department of pathology
- 0:19and laboratory medicine, and also the director of
- 0:22CHOP's Center for Diagnostic Innovation.
- 0:25We also have doctor Deborah Bowles, vice president
- 0:27research and development at LabCorp,
- 0:30and Doctor. Mindy Nye, vice president of LabCorp
- 0:32diagnostics.
- 0:34Stephen, Deborah, Mindy, so glad to have you
- 0:36all with us. Thanks for being here today.
- 0:38Thanks for having us. Thank you. Thank you.
- 0:40Great. Well, I know I already shared a
- 0:41little bit about your roles and and where
- 0:43you're coming from, but I'd love to hear
- 0:45a little bit from each of you just
- 0:47a bit about your background, how you landed
- 0:49in health care, and what you think is
- 0:50important for listeners to know going into the
- 0:52conversation.
- 0:53Would you like to start, Mindy? Sure. Thanks
- 0:55so much. I have a med tech background.
- 0:57And after a post doc in an academic
- 0:59academic medical center, I've spent the last twenty
- 1:01one years at LabCorp, and I've had a
- 1:03variety of technical and operational roles, and now
- 1:06have more of a corporate strategic role with
- 1:08the company. Wonderful. Thanks, Mindy.
- 1:11Deborah. Thanks. Hello, everyone. My name is Debbie
- 1:14Bowles. I'm vice president of
- 1:17I'm vice president of r and d,
- 1:19and have been with LabCorp for about fourteen
- 1:22years.
- 1:23Primarily, my role gets to,
- 1:26focus on the design of new tests and
- 1:29validation of those new tests in some of
- 1:31our specialty testing business units,
- 1:33as well as partnering with
- 1:36external partners to think of new innovative ways
- 1:39to bring that testing to our customers.
- 1:42Wonderful. Thank you. Good to know. Thanks, Deborah.
- 1:44Alright. And last but not least,
- 1:46Ethan.
- 1:47I'm Steve Master. My professional background is in
- 1:50laboratory medicine, specifically in clinical chemistry for many
- 1:53years.
- 1:53And, prior to my current role, I was
- 1:55the division chief for laboratory medicine at Children's
- 1:57Hospital of Philadelphia.
- 1:59Around six months ago, I took a new
- 2:00role that you alluded to as a vice
- 2:02chair for innovation
- 2:03at CHOP and also as the director of
- 2:05the Center for Diagnostic Innovation, which really reflects
- 2:08CHOP's institutional interest in putting more resources into
- 2:11biomarker development,
- 2:12into, supporting
- 2:14new translational research and clinical programs that require,
- 2:18rapid diagnostic development. Oh, great. Well, thank you
- 2:21for rounding us out with the interest, Steve.
- 2:22It's great to learn about what's going on
- 2:24at CHOP, your areas of focus, and I'm
- 2:26excited to dig into the partnership a little
- 2:27bit more. You know, we're seeing the landscape
- 2:30for academic medical centers shifting so much, especially
- 2:33in recent years. We're seeing constrained resources for
- 2:36research
- 2:37and evolving regulatory environment that is challenging to
- 2:40keep up with and greater urgency to demonstrate
- 2:43value and real world impact. So from where
- 2:45each of you sits, how is that reality
- 2:47reshaping
- 2:48how institutions,
- 2:50whether CHOP or what you're you both are
- 2:51seeing at LabCorp,
- 2:53think about the way that they can and
- 2:55should try to accomplish
- 2:57research on their own. You know, we're would
- 3:00love to just get a sense of that
- 3:01from from all three of you. But, Steven,
- 3:03would you like to get us started? Absolutely.
- 3:05As I said, CHOP has really recognized the
- 3:07importance of innovation and diagnostics
- 3:09to support many of our our internal programs,
- 3:11cell and gene therapy and things like that.
- 3:13But one of the things that we also
- 3:15realized is that we as in as much
- 3:17as our mission is to support child health
- 3:20at a national and international level, we really
- 3:22needed a partner. We needed someone who would
- 3:24help us to translate
- 3:25diagnostics that we developed into a much broader
- 3:27audience and a partner that could help us
- 3:30both in terms of the scope of getting,
- 3:32samples in to make testing available
- 3:34to individuals, children who live in perhaps underserved
- 3:37areas, but also in terms of the assay
- 3:39test, themselves, in terms of being able to
- 3:42roll out assays at a larger scale than
- 3:44we could do as a hospital.
- 3:47So the need and scale is really what
- 3:49drove Absolutely. Yes. Yeah. Really helpful to hear.
- 3:52So, Deborah, Mindy, how does this compare to
- 3:54what you're seeing across institutions?
- 3:56Yeah. I think that the upside is there's
- 3:58a lot to do, and the downside is
- 3:59there's a lot to do. Yeah. So there's
- 4:02the the old saying of, you know, if
- 4:03you wanna go fast, go alone. If you
- 4:05wanna go far, go together. And I think
- 4:07that we've been able to identify the strengths
- 4:10that our organizations
- 4:11can bring together
- 4:13to try to,
- 4:14maybe
- 4:15outbeat time just a little bit and try
- 4:17to accelerate things because the the need is
- 4:21so obvious and and acute. And I think
- 4:23that we have a shared passion to try
- 4:26to get to that delivery phase, you know,
- 4:28and,
- 4:30think about how
- 4:32the diagnostic test can impact then patient care.
- 4:34Yeah. Fantastic. What would you add, Debbie? Yeah.
- 4:37Thank you. I think we
- 4:40understand that each academic medical center is different,
- 4:43and so we've really taken the time to
- 4:45understand each other's strengths and think about where
- 4:49each of those could bring synergy to both
- 4:50of our institutions that are very aligned on
- 4:53mission. Yeah. Great. And I I know that
- 4:56all of you at one point have kind
- 4:58of touched on this,
- 4:59realization that in order to scale innovation and
- 5:02research and development,
- 5:04partnerships are very important. But we also know
- 5:06that health systems are more
- 5:08discerning than ever before about partnerships.
- 5:10Do we really need a partner? Can we
- 5:12do this internally? So is there a specific
- 5:14pressure point that that you've identified across partners
- 5:17or maybe even at CHOP that signals to
- 5:19you, okay, this is time for partnership rather
- 5:21than just internal adaptation?
- 5:24Well, I think we've addressed scale already Yeah.
- 5:27To a certain degree. I mean, I think
- 5:28scale can mean different things. In some cases,
- 5:30that means that there is testing for specialized
- 5:33pediatric disease, pediatric cancer, rare disease, things like
- 5:37that that CHOP can do. But as I
- 5:39said before, where CHOP can't necessarily bring it
- 5:41to the larger audiences efficiently.
- 5:44In those cases, with it's a rare enough
- 5:45disease, the CHOP lab can continue to handle
- 5:47that. We'll we, utilize the scale of our
- 5:50partners at LabCorp to think about getting samples
- 5:52to CHOP. But in other cases, we know
- 5:54that there are things that may have been
- 5:56developed at CHOP that have a much broader
- 5:59audience and where there's no way our internal
- 6:01lab could possibly,
- 6:03meet the demand that there will be nationally.
- 6:05And in those cases, it makes sense to
- 6:06have a partner where we, trust the reliability
- 6:10of their quality systems, where we know the
- 6:12the quality of the work that they do
- 6:14and to, transfer an assay,
- 6:16in that way. And then going to your
- 6:18point about the the the pressures and why
- 6:20we would consider this, I think there's a
- 6:22third piece to that, which is the things
- 6:24that we can do together that we could
- 6:26not do alone. Those are the things where
- 6:28we come together in a room and say,
- 6:29what are the unmet needs in pediatric health
- 6:31care? What are the things where we can
- 6:32leverage the the strengths of each institution,
- 6:36in order to do something that that is
- 6:38special? And some of those things might be
- 6:41who has access to what samples, who has
- 6:43access to what technology, who has what experience,
- 6:46with a specific kind of testing,
- 6:48but all of that comes together to alleviate
- 6:51that resource,
- 6:52constraint.
- 6:54And I think I would just add that
- 6:55what LabCorp truly values about,
- 6:58CHOP is the fact that the richness of
- 7:00information that they have about the direct patient
- 7:03care or the bedside that experience that they
- 7:05have Mhmm. So that we are treating the
- 7:08entire patient versus just looking at one particular
- 7:11genetic disease or rare genetic disease test in
- 7:14a transactional way. We're looking to support CHOP
- 7:18in ways that it makes sense and the
- 7:20patients by considering
- 7:22them, the patient themselves, their family,
- 7:25what care looks like six months after,
- 7:27they've been involved maybe in in a direct
- 7:31detection of of a diagnosis.
- 7:33But,
- 7:34the richness of experience that
- 7:37CHOP has and how that translates to the
- 7:39design of our test solutions
- 7:41that, meet the absolute need for the patient.
- 7:44Yeah. So interesting.
- 7:46And I wanna go a little deeper here
- 7:47on the collaboration between CHOP and LabCorp.
- 7:50I know this was intentionally structured around very
- 7:53specific and complimentary work streams,
- 7:56pediatric diagnostic co development, genomics, and bidirectional
- 8:00reference lab services.
- 8:02What does it look like so far to
- 8:04stand up a partnership around shared infrastructure and
- 8:07shared goals rather than a more
- 8:09transactional model? And why does that distinction matter?
- 8:12I think it's critically important. As Debbie just
- 8:14said,
- 8:15we are not as interested in the merely
- 8:18transactional. If those were merely transactional
- 8:20partnership, I don't think that we would have
- 8:22the level of trust that we have in
- 8:23the room. We have two aligned organizations
- 8:26who have shared values around pediatric health care,
- 8:29who are trying to determine how to best
- 8:30leverage
- 8:31the the strengths of both of them in
- 8:33order to achieve that ultimate goal. So I
- 8:35think that it's really allowed us to have
- 8:37very wide ranging discussions rather than sort of
- 8:39one assay at a time kind of, bespoke,
- 8:43interactions.
- 8:44Yeah. I think it's an amazing,
- 8:46coming together of matched
- 8:48energy,
- 8:49and interest and sort of hope to
- 8:52not diagnose what might,
- 8:54be a gap on either side, but actually
- 8:56use the synergies,
- 8:58in in a in a really productive way.
- 9:00Yeah. Absolutely. And I can sense the the
- 9:02synergies and the shared priorities of of both
- 9:05organizations just from talking to the three of
- 9:07you.
- 9:08And, Steve, just a quick follow-up. You know,
- 9:10as this partnership gets underway, what are you
- 9:13most focused on achieving in the near term,
- 9:15and what signals will tell you that you're
- 9:17on the right path? Absolutely. I think that
- 9:19deliverables are very important here. I think we're
- 9:22very close to launching,
- 9:24some testing
- 9:25that will be done either at CHOP or
- 9:27will be, moved to LabCorp. And I think
- 9:30that very quickly, you're, certainly over the next
- 9:33six to nine months, you're gonna see a
- 9:34number of areas in which we actually are
- 9:37bringing things to market to help the pediatric,
- 9:40population. So I think that that's gonna really
- 9:42be the proof that we've done this right,
- 9:43that we built the right infrastructure, that we
- 9:45can accomplish things together.
- 9:48But beyond that, if you ask about the
- 9:49signals in the long run that this is
- 9:51going well, I would say that you will
- 9:53that that I'm certainly looking forward to those
- 9:56joint things that we identify together for co
- 9:59development. The things that we don't know about
- 10:01now, but which we're actively meeting in person
- 10:03and virtually,
- 10:04to try and identify. And I think I'm
- 10:06I'm very excited by the conversations we've had
- 10:09already. Oh, yeah. Absolutely.
- 10:11And I I wanna stick with you just
- 10:13for a little bit longer, Steve. For academic
- 10:15medical center leaders who are weighing whether to
- 10:18strategically partner
- 10:20with an organization like LabCorp, whether when they're
- 10:23assessing if it's the right path, what do
- 10:26you recommend
- 10:27that they look for? You know, what do
- 10:28you wish someone had told you before you
- 10:30got started?
- 10:32I think it took me a while to
- 10:34realize how intentional we have to be about
- 10:36finding the right partner. Mhmm. We have to
- 10:38find someone
- 10:39anyone would have to find someone where there
- 10:41is a set of aligned values, where there
- 10:44are aligned,
- 10:45commitments to quality,
- 10:46commitments to patient care.
- 10:48And then beyond that, a set of complimentary
- 10:50strengths. So if we if I think back
- 10:52to how this relationship evolved, it really started
- 10:55a few years ago with some specific testing
- 10:57we had that we thought might meet a
- 10:59need for LabCorp. And that, that set in
- 11:01motion a number of conversations
- 11:04that over the years, made us realize more
- 11:06and more just how aligned we were, and
- 11:08that led to the the, the agreement that
- 11:11that's just been announced.
- 11:12So I think that that's really critical.
- 11:15You have to have the right partner, and
- 11:17not everyone is the right partner.
- 11:19Sounds like curiosity led you and great communication
- 11:22kind of led to those conversations in the
- 11:24partnership.
- 11:25So Mindy and Debbie, I'd love to hear
- 11:27from you on this too. When you think
- 11:29about what it takes to stand up a
- 11:30partnership like what you have with CHOP, what
- 11:33are the foundational capabilities or potentially
- 11:36the internal alignments that need to be in
- 11:38place on day one?
- 11:40I think the relationship between the teams has
- 11:43been very
- 11:44transparent and very trusting with the again, as
- 11:48Steve mentioned, the intent to have
- 11:50accountable deliverables
- 11:52that we are all working together towards,
- 11:54in a focused way.
- 11:56I think the more that we know about
- 11:57each other, the more that we understand the
- 12:00synergies that exist. And so conversation
- 12:03that allows us to
- 12:05see each other's strengths and
- 12:07brainstorm in a way to hit innovation
- 12:10is really energizing. And and so I think
- 12:13we've been looking to
- 12:15rely on the team itself to drive the
- 12:17biggest impact.
- 12:19And maybe just to add that LabCorp is
- 12:22very creative in the ways that we partner
- 12:24with small and large companies.
- 12:26And so we love the opportunity
- 12:28to
- 12:29really
- 12:30engage in a way that makes sense for
- 12:32the specific medical center's needs that we might
- 12:34be partnering with.
- 12:36Yeah. I think Debbie mentioned the word team,
- 12:38and I think that's what we've become.
- 12:40This was a a concept, and now it's
- 12:43a commitment, and we're really excited about what
- 12:45comes in the future. Oh, well, I can
- 12:47feel the excitement among the three of you
- 12:49and the alignment like I mentioned earlier. So
- 12:51it's been a great conversation. But before we
- 12:53hop, is there anything that we haven't covered
- 12:55that you think deserves more attention in this
- 12:57conversation?
- 12:58Well, I would just go back to the
- 13:00beginning. CHOP's mission is to improve the health
- 13:03of children and families.
- 13:04And
- 13:05we recognize that to do that with maximal
- 13:08effectiveness,
- 13:09we need a partner like LabCorp who will
- 13:11help us to take the diagnostics that we're
- 13:13developing or the diagnostics we may co develop
- 13:15together and to scale those nationally to help
- 13:17children's health all over the country and, in
- 13:20fact, internationally.
- 13:21I would say that this has the support
- 13:23of CHOP at the very highest level, and,
- 13:26we're excited to see where it goes.
- 13:28Fantastic. Mindy, Debbie, any final thoughts?
- 13:31I think just to say that we are
- 13:33very aligned in mission, and so we
- 13:37really are looking forward to play our part
- 13:40in delivering that to
- 13:42pediatric patients broadly.
- 13:44Yeah.
- 13:45Fantastic. Well, it's been such a pleasure having
- 13:47the three of you join the Becker's podcast
- 13:49today. So thank you for the time and
- 13:52the insights. I I think there's a lot
- 13:53for other health systems with similar missions to
- 13:56think about when it comes to partnerships here.
- 13:58So I wanna thank you all for for
- 13:59giving us insight to that. And, of course,
- 14:01we'd also like to thank our podcast sponsor,
- 14:03LabCorp.
- 14:04Listeners, be sure to tune into more podcasts
- 14:06from Becker's Healthcare by visiting our podcast page
- 14:09at beckershospitalreview.com.