Paroxysmal Nocturnal Hemoglobinuria | Oncology Today with Dr Neil Love: Management of Paroxysmal Nocturnal Hemoglobinuria

Research To Practice | Oncology Videos · Jul 26, 2023 · 42m

Featuring perspectives from Dr Carlos M de Castro, including the following topics:

Biology of paroxysmal nocturnal hemoglobinuria (PNH) (0:00)

Evolution of the PNH treatment landscape (13:07)

Selection and sequencing of therapies for patients with PNH (18:09)

Overview and presentation of extravascular hemolysis (23:50)

Case: A woman in her early 40s with PNH who developed Budd-Chiari syndrome and had an excellent response to C5 inhibition (26:57)

Case: A woman in her early 40s with a suboptimal response to ecluizumab followed by an excellent response to pegcetacoplan on the PEGASUS trial…