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Transcript

The Hormone Locksmith: Unlocking Energy, Balance & Longevity with Dr. Yvonne Karney · Ageless and Timeless Podcast®

• 0:11
  Speaker 1: Good morning everyone.
• 0:12
  Speaker 2: This is Michelle Hughes from Ageless and Timeless, and as always,
• 0:17
  Speaker 2: I have an incredible guest today. Her name is doctor
• 0:19
  Speaker 2: Yvonne Carney, and she started out as an obg yn
• 0:24
  Speaker 2: and now she's segued into a functional integrative medicine, still
• 0:29
  Speaker 2: focusing on primarily on women's health.
• 0:33
  Speaker 1: Correct, Yvonne, Yes, okay, So my question is how did you.
• 0:37
  Speaker 2: Make that journey from being a specialist in gynecology to
• 0:43
  Speaker 2: being a broader based functional medicine doctor.
• 0:48
  Speaker 3: You know, it's a special relationship that women have with
• 0:51
  Speaker 3: their obg yn and so I would frequently hear these
• 0:57
  Speaker 3: cries for help from women and it would always come
• 1:01
  Speaker 3: kind of at the end of the visit. You know,
• 1:03
  Speaker 3: they'd come in, we do their visit, and then towards
• 1:05
  Speaker 3: the end they'd be you know, my regular doctor says,
• 1:08
  Speaker 3: everything is okay, but I don't feel good. So it's
• 1:10
  Speaker 3: got to be my hormones. That's the last stitch effort
• 1:13
  Speaker 3: is that helped me? It's my hormones because all my
• 1:16
  Speaker 3: labs are normal, right.
• 1:19
  Speaker 1: And I after I heard that so.
• 1:21
  Speaker 3: Many times, it made me realize, you know, these women
• 1:24
  Speaker 3: weren't crazy, they weren't lying to me.
• 1:26
  Speaker 1: They weren't making it up, and I realized we were
• 1:31
  Speaker 1: missing something big.
• 1:33
  Speaker 3: We were missing something big, and I didn't have the
• 1:35
  Speaker 3: tools in my toolbox to help them, and so.
• 1:39
  Speaker 1: I started to I started.
• 1:40
  Speaker 3: It really opened my mind, and I was a diet
• 1:42
  Speaker 3: in the wool obg yn A Cogno's best.
• 1:46
  Speaker 1: I could quote all the studies.
• 1:48
  Speaker 3: It took a lot for me to realize that I
• 1:50
  Speaker 3: didn't have the right tools. And then I started living
• 1:53
  Speaker 3: it myself, where I was losing control over my emotions
• 1:57
  Speaker 3: and things that rolled off me one day made me
• 1:59
  Speaker 3: feel the next and I was like, oh, this is
• 2:02
  Speaker 3: what people are talking about, these mood swings and then
• 2:06
  Speaker 3: forgetfulness and this fatigue.
• 2:09
  Speaker 1: And that's when I really.
• 2:11
  Speaker 3: Dove into functional medicine, saying you know all because my
• 2:14
  Speaker 3: labs were normal too, and it made me realize that
• 2:18
  Speaker 3: normal is not the standard, and they don't test enough,
• 2:23
  Speaker 3: and they don't look at the labs with the right lens.
• 2:27
  Speaker 1: You have to use optimum and not normal. So all
• 2:29
  Speaker 1: of those.
• 2:30
  Speaker 3: Things made me realize that I couldn't help women with
• 2:33
  Speaker 3: the tools I was given, so I had to learn
• 2:36
  Speaker 3: new tools. And then about ten years ago, I left
• 2:40
  Speaker 3: my regular practice and started my own functional medicine practice.
• 2:44
  Speaker 2: So did you have to go back to school to
• 2:47
  Speaker 2: get more training? Where did you go and how did
• 2:50
  Speaker 2: you do it?
• 2:51
  Speaker 3: There's a lot of resources and I used many. So
• 2:54
  Speaker 3: initially I went to a bioidentical hormone symposium and I
• 2:59
  Speaker 3: was so embarrass at the time because I didn't know
• 3:01
  Speaker 3: the difference between bioidentical or not, because they don't teach
• 3:05
  Speaker 3: you on regular OBG y N training. We were just
• 3:08
  Speaker 3: told hormones or hormones and doesn't really matter, just give them.
• 3:12
  Speaker 3: And so I went to a bioidentical hormone symposium and
• 3:17
  Speaker 3: that weekend they were talking about, you know, hormones, But
• 3:20
  Speaker 3: then they started talking about adrenal and thyroid and inflammation
• 3:25
  Speaker 3: and gut and I'm like, wow, I need to really
• 3:28
  Speaker 3: dive in. So I did a fellowship through a four
• 3:33
  Speaker 3: M the A I knew you were going to say that,
• 3:37
  Speaker 3: And there's other ways that people can get their training.
• 3:40
  Speaker 3: It's really just a paradigm shift, you know, instead of
• 3:43
  Speaker 3: just using algorithms, you're really shifting into the why behind.
• 3:50
  Speaker 3: And so that paradigm shift is where the extra training
• 3:54
  Speaker 3: came in.
• 3:55
  Speaker 2: But Buddy Moon you know, the truth is that most
• 4:00
  Speaker 2: the women going to allopathic medical doctors do not really
• 4:05
  Speaker 2: get their hormones checked.
• 4:07
  Speaker 1: I mean, those doctors, many of them never even ask
• 4:11
  Speaker 1: about hormone health.
• 4:13
  Speaker 2: They do the regular CBC and all the you know,
• 4:16
  Speaker 2: typical cardiac lipid profiles, and but they don't look at
• 4:21
  Speaker 2: what is the super highway of our bodies, which is
• 4:24
  Speaker 2: and that's men and women. You know, we tend to
• 4:28
  Speaker 2: focus on women with postman apostle or let's say, you know.
• 4:33
  Speaker 1: Around fifty years old. But the truth is is.
• 4:36
  Speaker 2: That men are going through similar situations and they're never addressed.
• 4:41
  Speaker 2: So it's good that you know, people like you exist
• 4:44
  Speaker 2: and that people women find you. That's the key that
• 4:47
  Speaker 2: they find those doctors that are much more aware. So
• 4:53
  Speaker 2: what is it about HRT that makes it so important?
• 4:57
  Speaker 2: I mean, just give us a kind of a quick
• 5:00
  Speaker 2: synopsis of why. And I'm when I say HRG, I
• 5:05
  Speaker 2: really mean bioidentical b hr G. Yes, So why is
• 5:09
  Speaker 2: it so important and why is it really.
• 5:11
  Speaker 1: Critical not to do hr G versus b HRG.
• 5:16
  Speaker 3: And I hope that I hope that this becomes more
• 5:18
  Speaker 3: talked about. It finally is because the way that FDA
• 5:22
  Speaker 3: finally lifted the black box warning on hormone replacement therapy.
• 5:26
  Speaker 3: But we're talking twenty three years of women going into
• 5:30
  Speaker 3: menopause and being told that they shouldn't take hormones because
• 5:34
  Speaker 3: they're dangerous. But now finally with that being lifted, hopefully
• 5:40
  Speaker 3: the word will get out there. But then you get
• 5:42
  Speaker 3: into people that start prescribing hormones that maybe don't know
• 5:45
  Speaker 3: the intricacies of it and the difference between bioidentical and regular.
• 5:49
  Speaker 1: But back to your question.
• 5:51
  Speaker 3: Hormones are messengers and they tell your body what to do.
• 5:54
  Speaker 3: And the three key hormones for women that that can
• 6:00
  Speaker 3: decline in menopause, two of them, for sure decline, and
• 6:03
  Speaker 3: one of them very frequently declines are estrogen, which is
• 6:08
  Speaker 3: actually not truly a hormone, those three different hormones that
• 6:10
  Speaker 3: we call estrogen, but estra dial is the real hormone
• 6:14
  Speaker 3: that gives us the most benefit. So estra dial, progesterone,
• 6:20
  Speaker 3: and then possibly testosterone correct and those hormones are important
• 6:26
  Speaker 3: for brain health, they're important for mood stabilization, for sleep,
• 6:31
  Speaker 3: and those are very key components to our longevity. People
• 6:36
  Speaker 3: think that it's just hot flashes and those go away
• 6:39
  Speaker 3: after five years, So suck it up, buttercup. But it's
• 6:42
  Speaker 3: way more than that, and it's not just vanity either.
• 6:45
  Speaker 3: But hormones are good for your skin. Estrogen is very
• 6:47
  Speaker 3: good for your skin, and so women who have low estrogen,
• 6:51
  Speaker 3: they're going to wrinkle faster. Hormones are good for your
• 6:55
  Speaker 3: pelvic health. So if you're in a relationship and you
• 6:57
  Speaker 3: want to be able to maintain intimacy, estrogen is very
• 7:01
  Speaker 3: important for appropriate vaginal elasticity and moisture and the ability
• 7:07
  Speaker 3: to maintain sexual relations and the health of the tissues
• 7:12
  Speaker 3: down there declines with low hormones. Women get more bladder infections,
• 7:16
  Speaker 3: they start having pain with relations Eventually they start to
• 7:19
  Speaker 3: avoid it, and then it's the brain issue. So women
• 7:23
  Speaker 3: who take hormone replacement therapy have a much lower incidence
• 7:26
  Speaker 3: of dementia than women who don't. And you tell me,
• 7:30
  Speaker 3: when you don't need your brain anymore, when you can,
• 7:34
  Speaker 3: you know, get.
• 7:34
  Speaker 1: Off your hormones.
• 7:36
  Speaker 3: So's there's so many benefits that are that we know
• 7:41
  Speaker 3: now that is much more.
• 7:43
  Speaker 1: Than just hot flashes.
• 7:45
  Speaker 3: But the key is to use the hormones that are
• 7:48
  Speaker 3: the same structure that your body is to make.
• 7:51
  Speaker 1: Yeah, let's let's dive into that.
• 7:52
  Speaker 2: That was exactly what I was about to ask you,
• 7:54
  Speaker 2: is to differentiate between the traditional hormones, which are premarin
• 8:02
  Speaker 2: and et cetera, and the bioligentical which you're just talking about.
• 8:06
  Speaker 1: So tell us what that. Give us a little tutorial
• 8:09
  Speaker 1: on that, thank you.
• 8:11
  Speaker 3: Yes, the term bioidentical is made up, So we in
• 8:18
  Speaker 3: integrative medicine made up the term.
• 8:21
  Speaker 1: But we made it up for a reason, and it.
• 8:23
  Speaker 3: Means that at the molecular level, when carbon and hydrogen
• 8:28
  Speaker 3: and oxygen joined together to form a structure, at that level,
• 8:32
  Speaker 3: it has the same exact structure as what your ovaries
• 8:35
  Speaker 3: used to make. So hormones are the keys and the
• 8:40
  Speaker 3: hormone receptor is the lock and it has to fit
• 8:43
  Speaker 3: on the receptor exactly. And if you have a key
• 8:46
  Speaker 3: that's a slightly different shape, it may trigger that lock,
• 8:51
  Speaker 3: but it can also trigger a different lock, the lack
• 8:55
  Speaker 3: of inflammation or increased breast cancer risk.
• 8:59
  Speaker 1: And we don't want those things.
• 9:00
  Speaker 3: We want the keys that are available that our body
• 9:03
  Speaker 3: has made for decades. And if it's available like that,
• 9:07
  Speaker 3: it only makes sense to use it.
• 9:09
  Speaker 1: And there's some regular.
• 9:11
  Speaker 3: Doctors poo poo, the term bioidentical, and they say, we
• 9:14
  Speaker 3: made it up. But then they'll use terms like isomolecular,
• 9:17
  Speaker 3: which is exactly what bioidentical means, or body identical, which
• 9:22
  Speaker 3: is exactly what bioidentical means. It means at that level
• 9:26
  Speaker 3: of biochemical molecular structure, it's exactly the same as what
• 9:31
  Speaker 3: your ovaries used to make. Some people mistakenly use the
• 9:35
  Speaker 3: term natural versus synthetic. They mean, well, but that's not
• 9:39
  Speaker 3: the right term because natural just means it comes from nature,
• 9:43
  Speaker 3: and there's a lot of things that come from nature
• 9:45
  Speaker 3: that are not bioidentical to humans. You mentioned premarin. Premarin
• 9:50
  Speaker 3: is natural. It comes from horse urine, so that's natural.
• 9:55
  Speaker 3: And the way premarin got its name was pregnant mayor's
• 9:59
  Speaker 3: urine pre marie in and that that's very natural. But
• 10:03
  Speaker 3: it's not bioidentical unless you're a horse. So we if
• 10:07
  Speaker 3: we can take the if we can take the hormone
• 10:11
  Speaker 3: that is exactly like our ovaries used to make, it's
• 10:15
  Speaker 3: going to give us the benefits that we've had throughout
• 10:18
  Speaker 3: our life and minimize the risks because when our body
• 10:23
  Speaker 3: is used to it and has been, it's the same structure,
• 10:27
  Speaker 3: we metabolize it better and it doesn't trigger abnormal responses
• 10:32
  Speaker 3: that can be some of the risks that go along
• 10:35
  Speaker 3: with the other type of hormones.
• 10:37
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• 11:26
  Speaker 2: off your purchase of all their products. So, Yvon, what's
• 11:31
  Speaker 2: the source of a bioidentical hormone? I mean, obviously you
• 11:34
  Speaker 2: know the women who take them know that it's yams
• 11:38
  Speaker 2: are one of the big but what give us a
• 11:40
  Speaker 2: little more info on.
• 11:42
  Speaker 1: How it is defined as bioidentical? What's inside well, it doesn't.
• 11:48
  Speaker 3: That's very That's a great question, and it's often a confusion.
• 11:54
  Speaker 3: It doesn't really matter where it comes from. Yes, you
• 11:56
  Speaker 3: can get it from yams. I don't care if it
• 11:59
  Speaker 3: comes from a yam or a lab, as long as
• 12:03
  Speaker 3: at the molecular level it's xtra dial, it's not ethanol
• 12:07
  Speaker 3: estra dial or some other or madroxy progesterone acetate is
• 12:12
  Speaker 3: a progestin one, or you know. Those things don't matter.
• 12:18
  Speaker 3: The question of when it's made in the lab has
• 12:21
  Speaker 3: to do with are there other ingredients in it? Are
• 12:24
  Speaker 3: their solvents, are their residues? Are there are there chemicals
• 12:29
  Speaker 3: in it that are harmful to us in addition to
• 12:34
  Speaker 3: the hormone. But if it's at the molecular level the same,
• 12:40
  Speaker 3: I don't care if it comes from a plant or
• 12:43
  Speaker 3: a lab.
• 12:45
  Speaker 1: It's really using the.
• 12:47
  Speaker 3: Pure terminology and making sure that it has nothing harmful
• 12:51
  Speaker 3: in it. It has only the good bioidentical hormone, nothing else,
• 12:55
  Speaker 3: and it's delivered in a manner that your body knows
• 12:58
  Speaker 3: how to accept safely.
• 13:01
  Speaker 2: And then the compounding pharmacies are typically where people like
• 13:06
  Speaker 2: you go. So how do you know which compounding pharmacy
• 13:11
  Speaker 2: is the most efficacious, and then pick that for your
• 13:15
  Speaker 2: resource for your patients.
• 13:16
  Speaker 1: Well, thank you for asking that. And I also do
• 13:19
  Speaker 1: want to bring up that you.
• 13:20
  Speaker 3: Can get bioidentical hormones from regular pharmacies, and yes, and
• 13:25
  Speaker 3: so I often will start there because it's it's economically feasible,
• 13:31
  Speaker 3: it's a little bit less expensive.
• 13:33
  Speaker 1: So the key is for estrogeny dial don't take oral estrogen.
• 13:38
  Speaker 3: You need it in a transdermal form, either in a
• 13:41
  Speaker 3: cream or a patch, because if you take even bioidentical estradial,
• 13:46
  Speaker 3: if you take it in pill form, it gets digested,
• 13:50
  Speaker 3: so it's changed by your liver during digestion, and it
• 13:55
  Speaker 3: increases inflammation and that increases the risk.
• 13:59
  Speaker 1: Of heart attack and stroke.
• 14:01
  Speaker 3: So for all those years when we were told when
• 14:03
  Speaker 3: we were taking birth control pills, then birth control pills
• 14:06
  Speaker 3: have a risk of heart attack and stroke, it's because
• 14:09
  Speaker 3: it's oral.
• 14:09
  Speaker 1: Estrogen, that's right.
• 14:11
  Speaker 3: And so the lands dermal estrogen you bypass the liver
• 14:15
  Speaker 3: and it does not have that increased risk of heart
• 14:17
  Speaker 3: attack and stroke. And so the patch is a very
• 14:21
  Speaker 3: good starting point. The only issue is it only has
• 14:24
  Speaker 3: four doses, so I'll typically use one of the one
• 14:28
  Speaker 3: of the patches and then we'll do studies to see
• 14:31
  Speaker 3: if their levels are optimum. And if they're not and
• 14:34
  Speaker 3: we can't find that sweet spot with a patch, then.
• 14:37
  Speaker 1: We move over to cream.
• 14:40
  Speaker 2: But what about trophies, you know, sublingual or injections.
• 14:44
  Speaker 3: Of the estradyle injections injections have like intramuscular injections or
• 14:53
  Speaker 3: subcutaneous injections.
• 14:54
  Speaker 1: It's really hard to get a steady state.
• 14:56
  Speaker 3: You're going to get fluctuations which make it hard.
• 15:00
  Speaker 1: Pellets you can use.
• 15:01
  Speaker 3: Those are absorbed over time, slowly, and they last somewhere between.
• 15:05
  Speaker 3: The estradial pellets typically go away within three months, whereas
• 15:10
  Speaker 3: testosterone pellets last five to six months. The issue with
• 15:14
  Speaker 3: estradial pellets is that I don't recommend those for women
• 15:19
  Speaker 3: if they still have a uterus, if they have all
• 15:22
  Speaker 3: their female parts, because we really need to be careful
• 15:26
  Speaker 3: with the balance of estradial and progesterone, and if you're imbalanced,
• 15:30
  Speaker 3: then you can trigger some endometrial lining growth, submuterin lining
• 15:35
  Speaker 3: gross and get some postmenopozzle bleeding. And once that pellet's in,
• 15:41
  Speaker 3: it's in. You can't remove it. And if someone's using
• 15:43
  Speaker 3: a cream and they have some symptoms, you can stop
• 15:48
  Speaker 3: the cream and the symptoms will go away because the
• 15:50
  Speaker 3: estrogenerals don't stay high. But with a pellet, once it's in,
• 15:55
  Speaker 3: it's in. So I'll use testosterone pellets for women once
• 15:58
  Speaker 3: I know they're tolerating testosterone. And I'll occasionally use estradial
• 16:03
  Speaker 3: and testosterone pellets together for a woman who's had a hysterectomy.
• 16:07
  Speaker 3: But then you get into the issue that the testosterone
• 16:09
  Speaker 3: last six months, the estrogen only last three, So then
• 16:12
  Speaker 3: we go to a patch to make up the last
• 16:14
  Speaker 3: three months until they need another pellet.
• 16:16
  Speaker 1: It's a little complicated. It's complicated.
• 16:18
  Speaker 3: You need to work with someone who knows the finessas
• 16:21
  Speaker 3: of how to do it and evaluate the testing and
• 16:25
  Speaker 3: evaluate your symptoms.
• 16:27
  Speaker 1: Yes, but.
• 16:29
  Speaker 2: I'm so happy that you mentioned the balance of progesterone
• 16:32
  Speaker 2: and estrogen or estradout because I hear so many women
• 16:36
  Speaker 2: who are saying, oh, I'm on estrogen replacements therapy, but
• 16:40
  Speaker 2: I don't take any progesterone.
• 16:42
  Speaker 1: And I say that, I always say to them, do
• 16:45
  Speaker 1: not do that.
• 16:46
  Speaker 2: You know you need the balance of explain that a
• 16:48
  Speaker 2: little further to go deeper with that so people understand
• 16:51
  Speaker 2: why it's so important.
• 16:53
  Speaker 1: Yes, thank you.
• 16:54
  Speaker 3: I'm gonna break that up into two parts. The first
• 16:56
  Speaker 3: part is for a woman who still has all her
• 17:00
  Speaker 3: female parts, so she's never had a hysterectomy.
• 17:04
  Speaker 1: It is absolutely.
• 17:05
  Speaker 3: Crucial if you still have a uterus that you need
• 17:09
  Speaker 3: progesterone and estrogen because estrogen alone it stimulates the uterus
• 17:14
  Speaker 3: just a little bit and it's a little excitatory, and
• 17:18
  Speaker 3: so we need the progesterone to keep that calm. We
• 17:21
  Speaker 3: know from studies back in the seventies that unopposed estrogen
• 17:25
  Speaker 3: over time leads to endometrial hyperplasia and endometrial cancer. And
• 17:29
  Speaker 3: so that's how we learned way back in the seventies,
• 17:32
  Speaker 3: don't give estrogen alone because seventeen percent of those women
• 17:36
  Speaker 3: went on to develop eddimeutrial hyperplegia and cancer. And then
• 17:40
  Speaker 3: we learned, well, if you give them the progesterone with it,
• 17:43
  Speaker 3: then it prevents that. So for it's mandatory for people
• 17:47
  Speaker 3: who still have a uterus. Here's where obgyns frequently I
• 17:52
  Speaker 3: think now get it wrong, is that they're like, oh,
• 17:54
  Speaker 3: you've had a hysterectomy, you don't need progesterone anymore. We
• 17:56
  Speaker 3: can give you estrogen alone. Sure, there's no uterus to
• 18:00
  Speaker 3: get unopposed to estrogen. But progesterone is so calming it
• 18:04
  Speaker 3: has when it's this is the one that I will
• 18:07
  Speaker 3: use oral. It's the only one. I don't use testosterone
• 18:10
  Speaker 3: or estrogen oral. But progesterone oral is fabulous because as
• 18:16
  Speaker 3: it gets metabolized, it turns into a neurotransmitter like substance
• 18:21
  Speaker 3: called that mimics gabba, and GABA is a very calming neurotransmitter.
• 18:27
  Speaker 3: And so many women in their fifties and beyond struggle
• 18:32
  Speaker 3: with sleep, and so it's wonderful to give them that
• 18:36
  Speaker 3: progesterone which is calming to the nervous system and can
• 18:39
  Speaker 3: help them relax and sleep in the evenings. And so
• 18:42
  Speaker 3: I will frequently use oral progesterone in my menopausal women.
• 18:46
  Speaker 1: Yeah, and take it at night. Yeah, of course better.
• 18:50
  Speaker 2: And about one hundred milligram capsules, that's the.
• 18:53
  Speaker 3: One we know for sure prevents a demetrial hyperplasia. We
• 18:58
  Speaker 3: will we will follow the level with urine hormones and
• 19:02
  Speaker 3: some women one hundred milograms too much and so well,
• 19:07
  Speaker 3: and then in that case we'll use bioidentical project. I
• 19:09
  Speaker 3: mean we'll use compounded progesterone because the progesterone from the
• 19:15
  Speaker 3: regular pharmacy only comes in one hundred or two hundred milograms,
• 19:19
  Speaker 3: and they know that one hundred milograms for sure protects
• 19:23
  Speaker 3: the uterus. I think lower doses will too. There's just
• 19:26
  Speaker 3: not a lot of studies to, you know, to prove it.
• 19:29
  Speaker 3: So we can show that these women very closely if
• 19:31
  Speaker 3: they're on a lower dose than one hundred because they
• 19:33
  Speaker 3: don't tolerate the higher dose.
• 19:36
  Speaker 1: So now on the cream.
• 19:38
  Speaker 2: Because there are so many on Amazon, I was one
• 19:41
  Speaker 2: day I was kind of looking at their offerings because
• 19:45
  Speaker 2: I thought, you know, in case I run out of
• 19:47
  Speaker 2: my estrogen and I don't.
• 19:49
  Speaker 1: The form that I take it in the Estra dot,
• 19:52
  Speaker 1: and I don't get.
• 19:53
  Speaker 2: The pharmacy doesn't fulfill the prescription, and soon enough, I'd
• 19:57
  Speaker 2: better have a backup, so.
• 19:59
  Speaker 1: I some estrogen cream. But then I thought, am I
• 20:04
  Speaker 1: really getting the right Well, how do I know it's
• 20:06
  Speaker 1: not coming from China and right.
• 20:11
  Speaker 3: Exacting to verify that's stayed. Yeah, that's a little that's
• 20:16
  Speaker 3: a little risky.
• 20:17
  Speaker 1: It makes me nervous.
• 20:18
  Speaker 3: That's hormones are powerful and so we need to honor them.
• 20:23
  Speaker 3: We want to use them for their benefits, but honor
• 20:25
  Speaker 3: them and not overdose on them. That's right, And we
• 20:30
  Speaker 3: need to know, you know, we need to know that
• 20:32
  Speaker 3: it's been studied.
• 20:34
  Speaker 1: You know.
• 20:34
  Speaker 3: Compounding pharmacies are very rigorous in the studies that they do,
• 20:38
  Speaker 3: where they verify that this amount of cream contains this
• 20:42
  Speaker 3: much estra dial and if if, and they even put
• 20:45
  Speaker 3: it in a meter dose container, or they give you
• 20:48
  Speaker 3: a syringe where you can measure it down to the
• 20:50
  Speaker 3: tenth of a millimeter a milli liter that you're that
• 20:54
  Speaker 3: you're you know, rubbing on your skin.
• 20:57
  Speaker 1: But those other creams, we just don't know.
• 20:59
  Speaker 3: I don't think they're studied enough, and I would not
• 21:02
  Speaker 3: recommend using those for estradiol. Progesterone is a little different
• 21:06
  Speaker 3: because progesterone, it's almost impossible to harm yourself with progesterone,
• 21:11
  Speaker 3: and so there are some over the counter progesterone creams
• 21:14
  Speaker 3: and it's a great big bullseye for progesterone. It's much
• 21:18
  Speaker 3: bigger and your body tolerates a much wider range of
• 21:22
  Speaker 3: progesterone than estradiol. So I don't have a hard time
• 21:26
  Speaker 3: with women using an over the counter progesterone cream, but
• 21:30
  Speaker 3: if they're on estradial, I wouldn't.
• 21:33
  Speaker 1: I wouldn't use an over.
• 21:35
  Speaker 3: The counter progesterone cream if they're on estradiol because we
• 21:38
  Speaker 3: need to know that they're getting the balance levels.
• 21:42
  Speaker 1: That's right.
• 21:43
  Speaker 2: And yeah, so this is really important information that we're
• 21:48
  Speaker 2: talking about because it's all about balance, as you said,
• 21:52
  Speaker 2: and the right dosing, and it's customized to the individual.
• 21:58
  Speaker 1: Some people, like you said, some people would take less
• 22:01
  Speaker 1: than one.
• 22:01
  Speaker 2: Hundred milligrams of progesterone and she'll feel great, but others really,
• 22:07
  Speaker 2: you know, need that hundred or as you said, it
• 22:10
  Speaker 2: can even go higher. So with estrogen, there are three
• 22:15
  Speaker 2: different ones, as you said. So the estradel is the
• 22:18
  Speaker 2: one we've been talking about. That's the most common and
• 22:20
  Speaker 2: the most important. What about the other estriol and estrone?
• 22:25
  Speaker 3: Yes, so estriol is most common in pregnancy because it's
• 22:32
  Speaker 3: made out of estradol by the placenta, so women in
• 22:39
  Speaker 3: pregnancy will have higher levels of estriol. There are different
• 22:44
  Speaker 3: schools of thought amongst integrative doctors as far as what
• 22:48
  Speaker 3: is the best estrogen mix to give to women. Estrone
• 22:55
  Speaker 3: is not a lot made in the ovaries, it's mostly
• 23:00
  Speaker 3: from peripheral conversion of testosterone to estrogen, and it's done
• 23:06
  Speaker 3: in the fat cells.
• 23:08
  Speaker 1: So is estrone the one that you could be least
• 23:13
  Speaker 1: concerned about, but.
• 23:14
  Speaker 2: You should, Like I always used to get E one
• 23:17
  Speaker 2: and EAT two, and I and I thought E one
• 23:19
  Speaker 2: and EAT two is estradyl and estriol estriol, and then
• 23:23
  Speaker 2: E three is the estrone, which you really don't need
• 23:26
  Speaker 2: to be concerned about.
• 23:28
  Speaker 1: Estrone is the one.
• 23:30
  Speaker 3: Oh, Estrone is E one, estra dial is E two,
• 23:34
  Speaker 3: and estriol is E three. Good no recognition, there's no
• 23:40
  Speaker 3: reason to give estrone to someone zero. It doesn't give
• 23:44
  Speaker 3: you the benefits. It's not it doesn't help the brain.
• 23:48
  Speaker 3: It's it's it's converted from testosterone by fat cells to estrone.
• 23:54
  Speaker 1: That's how it's made.
• 23:55
  Speaker 3: The question is should you use estradiel alone or estree
• 24:00
  Speaker 3: with estradol, and which some women we use estriol alone
• 24:06
  Speaker 3: vaginally because there's not a lot of striol receptors to
• 24:10
  Speaker 3: give you the benefit of estrogen replacement therapy, but there
• 24:13
  Speaker 3: is in the vaginal tissue. So for women who for
• 24:17
  Speaker 3: some reason are afraid of hormone replacement therapy or they
• 24:22
  Speaker 3: don't want to take systemic hormone replacement therapy. We can
• 24:26
  Speaker 3: get a lot of pelvic floor vaginal health benefits using
• 24:30
  Speaker 3: a compounded estreol cream alone, but for systemic hormone replacement therapy,
• 24:37
  Speaker 3: this is where there's a difference of opinion. Some people
• 24:40
  Speaker 3: use a blend of fifty to fifty.
• 24:43
  Speaker 1: E two and E three.
• 24:44
  Speaker 3: Some people use a blend of it's called eighty twenty
• 24:48
  Speaker 3: eighty percent E three, twenty percent E two E two,
• 24:53
  Speaker 3: and then.
• 24:54
  Speaker 1: Other people will use estradial alone.
• 24:57
  Speaker 3: I use estra dial alone because when I used to
• 25:02
  Speaker 3: use the blend when I first when I first started,
• 25:07
  Speaker 3: But as I was thinking about this, women only have
• 25:14
  Speaker 3: significant amounts of estriol during pregnancy, and so in my mind,
• 25:19
  Speaker 3: I'm like, why do we want a menopausal woman to
• 25:23
  Speaker 3: be having estriol levels like.
• 25:26
  Speaker 1: She did when she was pregnant.
• 25:29
  Speaker 3: The benefits to the brain, the bone, the coal and
• 25:32
  Speaker 3: the skin we can get from estradieal, and so that's
• 25:36
  Speaker 3: what I use. Now. I just use the estradile alone,
• 25:39
  Speaker 3: and I'll use estriol just topically vaginally for women who
• 25:44
  Speaker 3: are concerned about taking estradle.
• 25:47
  Speaker 2: So that's really important informations are the important the thing
• 25:50
  Speaker 2: for women who are listening today right now to this podcast,
• 25:55
  Speaker 2: the biased which is the two and three your dial
• 26:00
  Speaker 2: and the estrial estu.
• 26:04
  Speaker 1: Astriol. So though that's called bias.
• 26:07
  Speaker 2: So if your doctor says, you know, I'm going to
• 26:10
  Speaker 2: give you a prescription for bias, you know now that
• 26:13
  Speaker 2: that's what it is. But that Yvonne is saying, you
• 26:15
  Speaker 2: really don't need the estriol.
• 26:18
  Speaker 1: Unless you're pregnant, and but you're making it.
• 26:21
  Speaker 2: Your body's making it itself, so you actually don't need it.
• 26:25
  Speaker 2: But I thought for me, my bioiget, my functional medicine
• 26:31
  Speaker 2: doctor gave me biased. But then I also use the syringe,
• 26:38
  Speaker 2: uh you know, and I'm postmenopausal, so I also use
• 26:41
  Speaker 2: the syringe for the vaginal tissue area, like you said,
• 26:45
  Speaker 2: for lubrication. So is that, in your opinion, is that
• 26:50
  Speaker 2: putting too much if you're using bias and the syringe
• 26:54
  Speaker 2: when in the syringe you only use when you're you know,
• 26:58
  Speaker 2: having intimacy, so you don't really need to use it
• 27:00
  Speaker 2: every day, although they say it on the bottle three
• 27:02
  Speaker 2: times a week just to keep the lubrication of the
• 27:06
  Speaker 2: vaginal tissue.
• 27:08
  Speaker 1: So what are your thoughts about that About using bias
• 27:11
  Speaker 1: plus the syringe.
• 27:13
  Speaker 3: It depends, you know, because when we're using biased, it's
• 27:17
  Speaker 3: from a compounding pharmacy, so the concentration is unlimited from
• 27:24
  Speaker 3: very low.
• 27:25
  Speaker 1: Concentration to very high concentration.
• 27:27
  Speaker 3: So as long as someone with knowledge is monitoring your levels,
• 27:36
  Speaker 3: if you get the benefit, because it could be cost
• 27:39
  Speaker 3: effective to say, I'm going to use most of it
• 27:42
  Speaker 3: on my arms and inner thighs because that's where it's absorbed. Well,
• 27:45
  Speaker 3: but I'm going to use a smite, you know, just
• 27:48
  Speaker 3: a little bit down there at bedtime.
• 27:51
  Speaker 1: Typically one to two, two to three times a week
• 27:54
  Speaker 1: is all.
• 27:54
  Speaker 3: You need to target that area because it increases elasticity, moisture,
• 28:01
  Speaker 3: collagen of the vagina. That's fine, as long as you're
• 28:06
  Speaker 3: monitoring your levels. Maybe you don't need as much on
• 28:09
  Speaker 3: your arms then, right, So that's where the monitoring comes in.
• 28:14
  Speaker 2: Okay, I didn't realize you could put it on your
• 28:16
  Speaker 2: arms or other parts of the body.
• 28:19
  Speaker 1: I thought it was just vaginal only. So that's interesting.
• 28:22
  Speaker 2: Does it help with creepy skin if you put estriol
• 28:27
  Speaker 2: And there's.
• 28:27
  Speaker 3: A huge optic right now in estradial creams because it
• 28:34
  Speaker 3: doesn't help with.
• 28:37
  Speaker 1: Skin. So it's estra dial not estriol. Okay, good. So
• 28:43
  Speaker 1: is there a.
• 28:46
  Speaker 2: Just your opinion, is there a cream a manufacturer of
• 28:50
  Speaker 2: a cream that you know is safe for women to
• 28:55
  Speaker 2: ask their doctors to prescribe.
• 28:57
  Speaker 3: Not without a compounding pharmacy, unfortunately breaks my heart. But
• 29:01
  Speaker 3: the regulares trace is the is the is the cream.
• 29:05
  Speaker 1: It has parabins in.
• 29:06
  Speaker 3: It, and parabins are not there are exactly They're in
• 29:12
  Speaker 3: a lot of creams because it makes them emulsify and
• 29:14
  Speaker 3: absorb easier.
• 29:15
  Speaker 1: But that's where I was talking about.
• 29:18
  Speaker 3: I don't care if it's from a compounding or traditional
• 29:21
  Speaker 3: pharmacy unless there's something that the traditional pharmacy is putting
• 29:27
  Speaker 3: in it that we don't need, like food coloring. Why
• 29:29
  Speaker 3: do you need food coloring? And your capsules they don't
• 29:32
  Speaker 3: have to look like em and ems. It's a medicine,
• 29:35
  Speaker 3: you know. So if there's food coloring in it, that's
• 29:37
  Speaker 3: a toxin.
• 29:38
  Speaker 1: We don't need that.
• 29:39
  Speaker 3: If there's perfume in it, that's a toxin, we don't
• 29:41
  Speaker 3: need that. If there's parabins in it, that's a toxin.
• 29:43
  Speaker 1: We don't need that.
• 29:44
  Speaker 3: So the advantage of the compounding pharmacy is you can
• 29:47
  Speaker 3: write and you know know that they're not putting those
• 29:52
  Speaker 3: extraneous ingredients in it, so that there's nothing harmful in
• 29:56
  Speaker 3: it at all.
• 29:58
  Speaker 1: So let's jump.
• 29:58
  Speaker 2: Over to castrastria and that's kind of the big T
• 30:01
  Speaker 2: is kind of a big controversy form.
• 30:05
  Speaker 1: So what are your thoughts.
• 30:07
  Speaker 2: Why are so many women thinking, oh, I don't need
• 30:11
  Speaker 2: to stostro own and that's only for men, and even
• 30:14
  Speaker 2: the doctors tell them you don't need it, but yet.
• 30:17
  Speaker 1: It's so important.
• 30:18
  Speaker 2: So what are your opinions about TRT and trastung distosterone
• 30:24
  Speaker 2: replacement therapy and how to.
• 30:28
  Speaker 1: The best method for assimilation?
• 30:31
  Speaker 3: Well, this is gaining traction, So I'm very excited about that.
• 30:36
  Speaker 3: I think when people becoming more vocal in some celebrities
• 30:40
  Speaker 3: now that are talking about their menopause journey so that
• 30:43
  Speaker 3: people aren't afraid to talk, it's finally becoming something that
• 30:48
  Speaker 3: people are talking about.
• 30:51
  Speaker 1: Here's a few facts. Your ovaries made two to.
• 30:55
  Speaker 3: Three times as much testosterone as estrogen, and so just
• 31:00
  Speaker 3: because we have one tenth the amount of testosterone as
• 31:05
  Speaker 3: a man, but it's so important for us and it's
• 31:09
  Speaker 3: the highest sex steroid by concentration in our body more
• 31:13
  Speaker 3: than astragile It's important for mood, decision, brain, muscle.
• 31:21
  Speaker 1: Bone, so many things. Yeah, absolutely get that. The problem
• 31:31
  Speaker 1: is nobody knows what optimal levels are.
• 31:36
  Speaker 3: The lab studies that look at normal range for testosterone,
• 31:42
  Speaker 3: there's many problems with that. One of the problems is
• 31:45
  Speaker 3: that the levels and women are so low. We're talking
• 31:49
  Speaker 3: nanograms per desclader, which is a tiny, tiny concentration. And
• 31:53
  Speaker 3: when you're checking a level in a man, if you're
• 31:55
  Speaker 3: trying to use the same machinery and methodology, because women
• 31:59
  Speaker 3: have ten times less, you're looking at the edges of detection.
• 32:05
  Speaker 3: So we've had to develop better equipment to be able
• 32:08
  Speaker 3: to even know with precision what a woman's testosterone levels
• 32:12
  Speaker 3: are because there's a you know, as you get lower
• 32:16
  Speaker 3: and lower concentration, it's harder to distinguish the value. But
• 32:21
  Speaker 3: the other issue is no studies have really been done.
• 32:24
  Speaker 3: They've looked at women and they've they typically put them
• 32:28
  Speaker 3: in like a scattergram and they say, of these four
• 32:31
  Speaker 3: hundred women that were still one of the criteria for
• 32:35
  Speaker 3: determining who was normal for testosterone was they were cycling.
• 32:39
  Speaker 3: So if you were a woman that had regular periods,
• 32:42
  Speaker 3: they checked your testosterone level, and then they platted all
• 32:45
  Speaker 3: these four hundred and something women out on a scattergram
• 32:48
  Speaker 3: and they figured out that this particular range was where
• 32:51
  Speaker 3: most of them, you know, had Well, testosterone has nothing
• 32:57
  Speaker 3: to do with your menstrual cycle, So just because you're
• 33:00
  Speaker 3: cycling doesn't mean that you have optimal testosterone levels. So
• 33:04
  Speaker 3: when we look at what is the reference range from
• 33:07
  Speaker 3: traditional labs, I think that it's artificially low. And I
• 33:12
  Speaker 3: know this because ten years ago, one of the very
• 33:17
  Speaker 3: well respected labs in the country, their normal range for
• 33:21
  Speaker 3: testosterone included zero. So the range for testosterone was for
• 33:27
  Speaker 3: free testosterone was zero to six. And I even called
• 33:32
  Speaker 3: the lab and I was like, seriously, zero, you don't
• 33:35
  Speaker 3: think you need any testosterone if you're a woman, because
• 33:37
  Speaker 3: if it goes down to zero, there's no such thing
• 33:40
  Speaker 3: as low testosterone because you can't have less than zero, right,
• 33:44
  Speaker 3: And so now they change the reference range to zero
• 33:46
  Speaker 3: point one.
• 33:49
  Speaker 2: Oh my goodness, And so that's number.
• 33:53
  Speaker 3: That's the question is like, the conundrum is that we
• 33:58
  Speaker 3: want to find where, when and feel the best, but
• 34:02
  Speaker 3: they're not having hyper androgen effects because we don't need
• 34:08
  Speaker 3: to be you know, The only right now FDA approved
• 34:11
  Speaker 3: use of testosterone and women is for transgender women who
• 34:15
  Speaker 3: you know, women who want to transition to men, and
• 34:17
  Speaker 3: so they give a man's dose testosterone. Well, if I
• 34:21
  Speaker 3: were to give you a man's dose of testosterone and
• 34:25
  Speaker 3: you didn't want to transition, you'd feel really good for
• 34:29
  Speaker 3: about a month, really good. You'd have energy and libido
• 34:33
  Speaker 3: and brain function, and you'd.
• 34:36
  Speaker 1: Be like, Wow, where's this been all my life?
• 34:38
  Speaker 3: But then within a month or so, you start to
• 34:42
  Speaker 3: get the hyper androgenic effects. You get chin hairs that
• 34:44
  Speaker 3: are too thick, you start losing, you have a male
• 34:47
  Speaker 3: pattern balding on your head, more whiskers, and then the
• 34:51
  Speaker 3: big one is you can have clteral enlargement and that
• 34:56
  Speaker 3: doesn't necessarily go away when you go back down on
• 34:58
  Speaker 3: the dose.
• 35:00
  Speaker 1: So we have to.
• 35:01
  Speaker 3: Find a good women's dose of testosterone, and right now,
• 35:05
  Speaker 3: the only way to get that is from a compounding pharmacy,
• 35:09
  Speaker 3: either in a cream or a pellet, or to use
• 35:12
  Speaker 3: teeny tiny injections. But again, the injections are a little
• 35:16
  Speaker 3: bit riskier because they get absorbed quicker, so you have
• 35:19
  Speaker 3: these highs and lows as opposed to a cream you're
• 35:22
  Speaker 3: going to get more of a steady state, and the
• 35:25
  Speaker 3: pellet you get a little bit of a bollus, meaning
• 35:27
  Speaker 3: a high level, but it comes down pretty good to
• 35:30
  Speaker 3: that lower you know, the average range. It's not absorbed
• 35:35
  Speaker 3: quickly like an intermuscular injection. And there are women right
• 35:39
  Speaker 3: now who's gynecologist is giving them testosterone in the form
• 35:43
  Speaker 3: of the man's testosterone gel and say, well, just take
• 35:48
  Speaker 3: a quarter of a pump, or take a tenth of
• 35:51
  Speaker 3: a pump. It's like, how can you take a tenth
• 35:53
  Speaker 3: you know what, You're pressing the pump down and you're
• 35:56
  Speaker 3: trying to stop one tenth of.
• 35:57
  Speaker 1: The way down.
• 35:58
  Speaker 3: That's not measurable interact because that's ten times the dose
• 36:02
  Speaker 3: that you need.
• 36:04
  Speaker 2: Well, not only that, but you know when people do
• 36:07
  Speaker 2: test their just lebs on tystostrumee. But a lot of
• 36:11
  Speaker 2: these doctors don't even understand you need to do free
• 36:14
  Speaker 2: testosterone and the other testosterone the same like the thyroid.
• 36:21
  Speaker 2: Very often they only do T s H, which is
• 36:23
  Speaker 2: really not a thyroid, it's a pituitary. So so talk
• 36:27
  Speaker 2: about that for a moment. How to know from your
• 36:30
  Speaker 2: labs whether or not you are getting enough.
• 36:34
  Speaker 1: To stosterone when that's a that's a loaded question.
• 36:40
  Speaker 3: There's a lot of different opinions on this, so I'm
• 36:43
  Speaker 3: going to give you mine, which, of course I think
• 36:45
  Speaker 3: is right, because otherwise I wouldn't be operating.
• 36:48
  Speaker 1: Well, that's why I asked.
• 36:52
  Speaker 3: I will check a serum testosterone on a woman if
• 36:57
  Speaker 3: they have a pellet or if they're not on any
• 37:00
  Speaker 3: testosterone at all, and I think it's reliable if someone
• 37:04
  Speaker 3: is on a testosterone cream. I do not check a
• 37:07
  Speaker 3: serum testosterone level because I just don't think that it
• 37:12
  Speaker 3: gives an adequate level of the body burden. When we
• 37:16
  Speaker 3: check a serum level, we're checking a venus blood flow,
• 37:21
  Speaker 3: and we're assuming that what's happening in the bloodstream of
• 37:25
  Speaker 3: the of the vein in the is what is going
• 37:30
  Speaker 3: into the body. But these hormones are fat soluble, They're
• 37:34
  Speaker 3: made out of cholesterol. We now think that they're transported
• 37:38
  Speaker 3: mostly through the lymph system, which transports fat soluble things
• 37:42
  Speaker 3: much more than the bloodstream does. And so I'm not
• 37:47
  Speaker 3: convinced that a vena puncture sample is going to give
• 37:51
  Speaker 3: me a good level of a cream being absorbed through
• 37:55
  Speaker 3: the skin and transported through the body and the lymph
• 37:58
  Speaker 3: so for women who are on on a cream, I
• 38:01
  Speaker 3: will either use salivary or urine. Oh okay, because I've
• 38:07
  Speaker 3: seen testosterone levels in the blood below when they're on
• 38:13
  Speaker 3: a pretty good dose of testosterone, and then I've gone
• 38:15
  Speaker 3: back and checked salivary or urine and those levels are high.
• 38:22
  Speaker 1: Oh wow, that's important to know. So okay. So when
• 38:29
  Speaker 1: a woman comes to you and says.
• 38:34
  Speaker 2: You know, all my hormones are normal according to the results,
• 38:38
  Speaker 2: So she's gotten but I don't feel well.
• 38:41
  Speaker 1: What's the first thing that you do as the physician.
• 38:45
  Speaker 2: What's the first thing that you check to try to
• 38:49
  Speaker 2: be a detective about why am I not feeling well
• 38:53
  Speaker 2: and yet I'm getting these results that are allegedly normal.
• 38:57
  Speaker 1: Well, here here is.
• 38:59
  Speaker 3: This is my passion, and so I call myself the
• 39:02
  Speaker 3: hormone locksmith, okay, because the hormones need receptors, right, and
• 39:08
  Speaker 3: we need keys. The hormones are the keys, but we
• 39:11
  Speaker 3: need healthy locks also. So if you have beautiful keys
• 39:16
  Speaker 3: and rusty locks, what happens? The door doesn't open?
• 39:21
  Speaker 1: And there's so many people.
• 39:22
  Speaker 3: And I'm glad that hormones are getting attention and they're
• 39:25
  Speaker 3: very important, but we cannot forget the locks. We cannot
• 39:28
  Speaker 3: forget cellular health, receptor health, sell membrane health. And that's
• 39:34
  Speaker 3: the issue that a lot of bioidentical hormone doctors might miss.
• 39:39
  Speaker 3: They keep giving more and more hormones because the woman
• 39:42
  Speaker 3: has hormone deficiency symptoms, even though.
• 39:45
  Speaker 1: Her levels might actually be good.
• 39:47
  Speaker 3: If they don't feel good and their levels are normal,
• 39:49
  Speaker 3: the first thing I do is I'm like, well, what
• 39:51
  Speaker 3: are they calling normal? Are they checking them right? And
• 39:54
  Speaker 3: is it optimal? But then if their levels are optimal,
• 39:58
  Speaker 3: I'm like, okay, then something else is causing this. Maybe
• 40:01
  Speaker 3: you're maybe you have rusty locks. Do you have environmental
• 40:04
  Speaker 3: toxic exposures, Do you have gut inflammation? Do you have
• 40:07
  Speaker 3: super high stress? Do you have micronutrient deficiencies, Because if
• 40:11
  Speaker 3: you don't have the right micronutrients, then your body can't
• 40:14
  Speaker 3: respond to the hormones.
• 40:16
  Speaker 1: Do you have highlight thyroidism?
• 40:18
  Speaker 3: Because if you don't have energy to respond to the hormones,
• 40:21
  Speaker 3: then you can't make the stuff to that the hormones
• 40:24
  Speaker 3: is telling your body to make.
• 40:25
  Speaker 1: So it's the whole you have to do, the whole person.
• 40:30
  Speaker 1: You know.
• 40:30
  Speaker 2: This is why functional medicine is becoming such a huge
• 40:35
  Speaker 2: demand because you know, doctors like you are looking as
• 40:39
  Speaker 2: the whole body, and they're looking at the source, not
• 40:43
  Speaker 2: just the symptoms. So they're looking at the root cause
• 40:45
  Speaker 2: and trying to get to you know, understand that rather
• 40:49
  Speaker 2: than just giving you a pill to address a symptom,
• 40:52
  Speaker 2: which then causes more side effects from that. You know
• 40:55
  Speaker 2: that particular chemical ho that that pill. So all right,
• 40:59
  Speaker 2: I'm glad you mentioned the thyroid because that's another kind
• 41:03
  Speaker 2: of big black hole.
• 41:04
  Speaker 1: One because the measuring of the.
• 41:06
  Speaker 2: Thyroid, as I mentioned earlier, is so inadequate.
• 41:10
  Speaker 1: And two, you know, it's.
• 41:12
  Speaker 2: The most underdiagnosed condition I think in our health, So
• 41:18
  Speaker 2: talk to us about you know, how to manage your thyroid.
• 41:22
  Speaker 3: Hormone is like our body's thermostat, so it really sets
• 41:26
  Speaker 3: our metabolism. It's absolutely necessary to make energy. It's what
• 41:31
  Speaker 3: helps to shuttle things into the internal battery called the mitochondria,
• 41:35
  Speaker 3: which make energy inside of ourselves, and so we absolutely
• 41:40
  Speaker 3: need thyroid hormone. Thyroid is the gland in your neck
• 41:45
  Speaker 3: that makes a pre hormone called T flour which your
• 41:49
  Speaker 3: body needs a different hormone called T three, and that
• 41:53
  Speaker 3: gets converted elsewhere in the body, and the hormone that
• 41:59
  Speaker 3: traditional and doctors have been chained trained to check is TSH, which,
• 42:05
  Speaker 3: as you already said, is a pituitary hormone. It's thyroid
• 42:09
  Speaker 3: stimulating hormone, it's not thyroid hormone. So the assumption is
• 42:14
  Speaker 3: that if your TSH is normal, and the problem with
• 42:18
  Speaker 3: that is there's a twenty fold range that's called normal
• 42:21
  Speaker 3: range for TSH. It goes from zero point five to
• 42:28
  Speaker 3: four point something.
• 42:29
  Speaker 1: I mean, it's a huge range, and that's problem number one.
• 42:35
  Speaker 3: Problem number two is it's not necessarily indicative of your
• 42:38
  Speaker 3: body's thyroid hormone balance. If your brain has too much
• 42:44
  Speaker 3: stress or has been damaged by environmental toxic exposures and
• 42:48
  Speaker 3: the pituitary gets knocked out by these massive environmental toxic exposures,
• 42:55
  Speaker 3: then the brain doesn't supervise the body very well. So
• 42:57
  Speaker 3: you could have low thyroid hormone and a normal TSH.
• 43:02
  Speaker 3: So you cannot use TSH as the proxy all the time.
• 43:06
  Speaker 3: And some people it works, but in others it doesn't.
• 43:09
  Speaker 3: So at a minimum, you need to check t s
• 43:13
  Speaker 3: H three, T four and free T three. Right, very
• 43:18
  Speaker 3: few traditional doctors actually check free T three and I
• 43:22
  Speaker 3: add reverse T three in they're also because reverse T
• 43:25
  Speaker 3: three is what T four can become either T three
• 43:29
  Speaker 3: or reverse T three, and they're not the same. Right
• 43:34
  Speaker 3: stimulates the receptor. Reverse T three blocks the receptor. I
• 43:38
  Speaker 3: tell people this, Look at your two hands. They have
• 43:41
  Speaker 3: the same ingredients. They each have four fingers and a thumb.
• 43:45
  Speaker 3: That's like T three and reverse T three, but they're
• 43:48
  Speaker 3: not interchangeable because the thumb's in a different place, and
• 43:52
  Speaker 3: so ther the hormone receptor is a right handed glove,
• 43:59
  Speaker 3: and T three is your right hand. It fits perfectly
• 44:01
  Speaker 3: into the right handed glove. But reverse T three is
• 44:04
  Speaker 3: your left hand, and how does that fit into a
• 44:07
  Speaker 3: right handed glove.
• 44:09
  Speaker 1: It doesn't. And so you're so glad that you're, oh,
• 44:12
  Speaker 1: go ahead, finish what you're saying.
• 44:13
  Speaker 3: If you don't check that, then you could think that
• 44:17
  Speaker 3: someone's doing fine because their T four is okay, But
• 44:22
  Speaker 3: biochemically they're hypothyroid because they're making the blocker instead of
• 44:27
  Speaker 3: the one that actually triggers the response.
• 44:30
  Speaker 2: I think people can just understand the T four is
• 44:33
  Speaker 2: like your reserve chank, and if you're thinking analogous to
• 44:37
  Speaker 2: your car, it's like you have a reserve tank, but
• 44:40
  Speaker 2: if you're not converting back into the actual gas tank
• 44:45
  Speaker 2: of T three, which is G three, then you're not
• 44:48
  Speaker 2: getting the use of the thyroid hormone.
• 44:51
  Speaker 1: It's just sitting. It's kind of like dormant, right.
• 44:55
  Speaker 2: So yeah, and then and then the other issue is
• 44:57
  Speaker 2: what you said that so many doctors don't even check
• 45:00
  Speaker 2: for T three or reverse T three And what about
• 45:03
  Speaker 2: all the antibodies.
• 45:05
  Speaker 3: Oh, my goodness, And that's a huge red flag. Antibodies
• 45:08
  Speaker 3: is immune system dysfunction. And it just so happens that
• 45:12
  Speaker 3: hashimotos which is an autoimmune condition where your immune system
• 45:16
  Speaker 3: attacks your thyroid gland. Hashimotives is the number one cause
• 45:20
  Speaker 3: of hypothyroidism in the United States. And the traditional the
• 45:25
  Speaker 3: traditional approach is, oh, it doesn't matter, just check the
• 45:28
  Speaker 3: thyroid hormone because you can give them thyroid hormone. If
• 45:31
  Speaker 3: too much thyroid gland gets destroyed, then then go on
• 45:35
  Speaker 3: synthroid or level thyroxin. But the issue is if you
• 45:39
  Speaker 3: have immune system dysfunction, that's important. If your immune system
• 45:42
  Speaker 3: is attacking body parts, that's a big deal and it
• 45:46
  Speaker 3: can turn into other forms of autoimmunity if you don't
• 45:49
  Speaker 3: address why the immune system is malfunctioning in the first place.
• 45:54
  Speaker 1: Why is it attacking? You know? That brings up a
• 45:56
  Speaker 1: really good point.
• 45:57
  Speaker 2: We talk about autoimmunity and eighty five percent of autoimmune
• 46:02
  Speaker 2: diseases are women.
• 46:03
  Speaker 1: Why is that and what is it that we can
• 46:06
  Speaker 1: do to help women to not.
• 46:11
  Speaker 2: Have that high percentage, in other words, not have autoimmunity?
• 46:15
  Speaker 1: And you know, so give us.
• 46:19
  Speaker 2: Your thoughts about women and autoimmune diseases.
• 46:23
  Speaker 3: This goes This is dabbling now into Chinese medicine, and
• 46:30
  Speaker 3: it sounds a little woogle, but it just makes so
• 46:32
  Speaker 3: much sense to me when I heard it explain this
• 46:35
  Speaker 3: way that there's implosion where you fold in and implode
• 46:40
  Speaker 3: on yourself, and then there's explosion, which is like rage
• 46:43
  Speaker 3: and explosion. Like a heart attack is explosion. Autoimmunity is implosion.
• 46:50
  Speaker 3: Your body's attacking itself. Your body's trying to commit suicide.
• 46:55
  Speaker 3: So why I think for women, the reason we get
• 46:59
  Speaker 3: it more is because we don't take care of ourselves.
• 47:02
  Speaker 1: We care for everybody else. We're always giving.
• 47:05
  Speaker 3: We are afraid to put ourselves first, and so with
• 47:09
  Speaker 3: that depletion over and over and over again, that leads
• 47:15
  Speaker 3: to the illness that is the implosion illness and you
• 47:19
  Speaker 3: s there's.
• 47:19
  Speaker 2: A psychological element to this, or obviously we know there's
• 47:24
  Speaker 2: a toxicity element.
• 47:26
  Speaker 3: Everybody, almost everyone who has autoimmunity has some significant history
• 47:34
  Speaker 3: of trauma in their life exactly. And if you don't
• 47:37
  Speaker 3: ask it as a doctor, people aren't going to divulge it.
• 47:41
  Speaker 3: And we can't change the past, but we can certainly
• 47:45
  Speaker 3: get control of the nervous system, because trauma is an
• 47:48
  Speaker 3: issue of lack of nervous system regulation. Your body gets
• 47:51
  Speaker 3: trapped in the fight or flight emergency mode because of
• 47:55
  Speaker 3: unresolved trauma. It's stored in your body. There's so much
• 47:59
  Speaker 3: data on that now, and if you do not know
• 48:02
  Speaker 3: how to go in there, get the release, get it released,
• 48:07
  Speaker 3: and regulate the nervous system. God made us to live
• 48:10
  Speaker 3: our lives in the parasympathetic, relaxed mode. But when we
• 48:14
  Speaker 3: are a history of trauma, or we're too busy and
• 48:17
  Speaker 3: we're super high stressed, we're living twenty four.
• 48:20
  Speaker 1: Seven in the sympathetic mode.
• 48:22
  Speaker 3: And that is a setup for cancer and autoimmunity and
• 48:25
  Speaker 3: any other disease.
• 48:27
  Speaker 2: And I asked my functional medicine doctor, why can't we
• 48:31
  Speaker 2: just test cortisol? You know, she said, No, it's very
• 48:35
  Speaker 2: difficult to measure cortisol just in the blood in the morning.
• 48:39
  Speaker 2: Very she said, in the morning, your cortisol is always
• 48:41
  Speaker 2: going to be lower because you just awakened.
• 48:43
  Speaker 1: But later in the day, you know, so it curve.
• 48:48
  Speaker 3: It climbs the mountain, so it's low when you first
• 48:51
  Speaker 3: wake up, then it goes high, and then it goes
• 48:53
  Speaker 3: down again, and it's.
• 48:53
  Speaker 1: Supposed to be lest as you get close and it's
• 48:56
  Speaker 1: pretty big range.
• 48:57
  Speaker 3: So just checking one hormone level throughout the day doesn't
• 49:00
  Speaker 3: tell you if your curve is normal. And it's not
• 49:03
  Speaker 3: practical to get your blood drawn four times in one
• 49:06
  Speaker 3: day to know your blood hormone. So we'll check saliva
• 49:09
  Speaker 3: or urine in multiple samples throughout a day and get
• 49:12
  Speaker 3: a good picture of the cortisol curve. The other issue
• 49:15
  Speaker 3: is even me as a doctor, if somebody's coming at
• 49:17
  Speaker 3: me with a needle, my cortisol goes up a little
• 49:20
  Speaker 3: bit because you're like, oh, I think they know what
• 49:21
  Speaker 3: they're doing. Last time I got a cruise. I hope
• 49:24
  Speaker 3: they get me on the first stick, you know, So
• 49:26
  Speaker 3: that little little bit of anxiety about here comes someone
• 49:30
  Speaker 3: with five tubes of blood five tubes and a mile
• 49:32
  Speaker 3: that's going to be enough to spike your cortisol a
• 49:34
  Speaker 3: little bit. So blood is not a very good indicator,
• 49:39
  Speaker 3: but so.
• 49:40
  Speaker 1: The it okay. So is there a point in life
• 49:46
  Speaker 1: where it's too late for HRT?
• 49:51
  Speaker 3: What a great question, and that's the million dollar question.
• 49:56
  Speaker 3: The studies way back found that women got the most
• 50:01
  Speaker 3: benefit if they started.
• 50:03
  Speaker 1: The earlier they started.
• 50:04
  Speaker 3: In menopause, the better, even in the transition before they're
• 50:08
  Speaker 3: fully menopausal.
• 50:09
  Speaker 1: The most benefit is the earlier you start.
• 50:12
  Speaker 3: But then you look at like, does that mean you
• 50:15
  Speaker 3: get zero benefit later just because you don't get the
• 50:18
  Speaker 3: most benefit. I'm not gonna withhold that if I know
• 50:23
  Speaker 3: that other things are on board.
• 50:24
  Speaker 1: Now, the older we are, the more.
• 50:26
  Speaker 3: Likely we have rusty locks, right, because we've lived longer
• 50:29
  Speaker 3: and abused our bodies a little bit longer and breathed
• 50:31
  Speaker 3: in more toxins longer, and so we meet, you know,
• 50:34
  Speaker 3: we need to make sure we have that, and then
• 50:37
  Speaker 3: we do want to do a cardiovascular evaluation to make
• 50:40
  Speaker 3: sure that someone's not at super high risk for heart disease.
• 50:43
  Speaker 3: Because one of the things is with hormone replacement therapy
• 50:47
  Speaker 3: with estrogen, it increases the elasticity of the blood vessels.
• 50:52
  Speaker 3: And the theoretical risk is if someone has a claw
• 50:55
  Speaker 3: a plaque there, and now all of a sudden, you
• 50:58
  Speaker 3: make it more trampoline like, it could dislodge the plaque
• 51:02
  Speaker 3: and lead to a heart attack. But I think that's
• 51:07
  Speaker 3: more of a theoretical risk. And since we're not talking
• 51:09
  Speaker 3: about oral estrogen, we're talking about transdermal. But I still
• 51:15
  Speaker 3: will do a cardiovascular evaluation of advanced slipid testing on
• 51:19
  Speaker 3: someone and make sure that they don't have massive cardiovascular
• 51:22
  Speaker 3: inflammation before I start them on hormone replacement therapy.
• 51:25
  Speaker 1: If they're outside the tenure window, well.
• 51:28
  Speaker 2: Any good functional medicine doctor is going to want a baseline.
• 51:32
  Speaker 3: Yeah, you knows on the killer of women is heart disease,
• 51:36
  Speaker 3: and the first time of heart disease is a heart attack.
• 51:39
  Speaker 1: That's right.
• 51:40
  Speaker 3: So you know, we don't want to we don't want
• 51:42
  Speaker 3: to optimize your hormones and have you walk out the
• 51:44
  Speaker 3: door and have a heart attack because nobody checked, not
• 51:47
  Speaker 3: because the hormones caused it. But we want to be
• 51:49
  Speaker 3: able to intervene on anything we can to improve your
• 51:52
  Speaker 3: quality of your health span.
• 51:55
  Speaker 2: So do you have any secret formula for measuring the
• 52:00
  Speaker 2: body's toxic load, like if a let's just use the
• 52:04
  Speaker 2: example of the woman that's coming into you and saying.
• 52:06
  Speaker 1: No matter what I do, I don't lose weight, or I.
• 52:09
  Speaker 2: Don't feel I always feel lethargic, or I don't have
• 52:13
  Speaker 2: a libido anymore. You know, the usual complaints that you hear,
• 52:17
  Speaker 2: and yet you know their hormones allegedly are normal. So
• 52:21
  Speaker 2: you know, obviously we have this whole body approach to
• 52:25
  Speaker 2: medicine that you're to health. So how do you deal
• 52:28
  Speaker 2: with getting the toxic load understood by first by the
• 52:34
  Speaker 2: patient and then addressed with an action plan that will
• 52:38
  Speaker 2: make a difference and detoxified to the point where those
• 52:43
  Speaker 2: signaling molecules, the hormones are now going to have far
• 52:47
  Speaker 2: more impact.
• 52:48
  Speaker 3: That With my patients, our first visit is over an hour,
• 52:52
  Speaker 3: and I think it you really need to know someone's story,
• 52:55
  Speaker 3: and that's what I do for the whole first visit
• 52:57
  Speaker 3: as I listen to their story. Did they live or farmland,
• 53:00
  Speaker 3: Did they live in the city where they sick growing up?
• 53:03
  Speaker 3: You know, did their parents smoke? All of those things
• 53:07
  Speaker 3: are suggestive of a higher toxic load. Did they get
• 53:11
  Speaker 3: an illness young in life that makes me think that
• 53:13
  Speaker 3: they have a high toxic burden.
• 53:16
  Speaker 1: So I listen to those things.
• 53:18
  Speaker 3: I know we all have toxins, and so for a
• 53:21
  Speaker 3: lot of my patients, we just do a toxin reduction
• 53:25
  Speaker 3: strategy where we get rid of as many ongoing exposures
• 53:29
  Speaker 3: as we can and then we gently, safely at the
• 53:33
  Speaker 3: pace the body can handle, start.
• 53:34
  Speaker 1: Removing the toxins.
• 53:36
  Speaker 3: And that's what we work on our patients with when
• 53:39
  Speaker 3: we take them in and into the practice, is to
• 53:41
  Speaker 3: make sure that we're getting rid of stored up toxins
• 53:45
  Speaker 3: that have accumulated over the years. But if there's a
• 53:49
  Speaker 3: story that's a significant illness that I know, or they
• 53:53
  Speaker 3: have a significant exposure they lived in a moldy house
• 53:58
  Speaker 3: for ten years and they've had allergies and brain fogs sense,
• 54:02
  Speaker 3: then I will sometimes order toxicity testing. And those are
• 54:06
  Speaker 3: functional medicine labs, and there's different ones available. Most of
• 54:12
  Speaker 3: them are urine tests. We can check for micotoxins, which
• 54:16
  Speaker 3: is exposure to mold. We can test for chemicals, which
• 54:20
  Speaker 3: are industrial chemicals, and then there's heavy metal testing. Mercury, arsenic, cadmium, lead,
• 54:26
  Speaker 3: aluminium are the big ones, and so there are functional
• 54:30
  Speaker 3: medicine tests that we can do to assess the body burden,
• 54:34
  Speaker 3: and I will reserve those for people who have a
• 54:38
  Speaker 3: story that makes me suspicious that they're going to be
• 54:40
  Speaker 3: significantly high and we want to follow those levels down.
• 54:43
  Speaker 3: We all have them, and we might all benefit from
• 54:47
  Speaker 3: the testing, but I try to be cost conscientious because
• 54:50
  Speaker 3: those tests are not covered by insurance, and if I
• 54:53
  Speaker 3: think that I can act and get someone feeling really good,
• 54:56
  Speaker 3: then I do the action without knowing those levels initially,
• 55:01
  Speaker 3: because probably seventy five percent of my patients feel so
• 55:04
  Speaker 3: much better going through the program and the protocols that
• 55:07
  Speaker 3: they don't.
• 55:08
  Speaker 1: Need to do the toxicity testing in the end.
• 55:11
  Speaker 3: Yes, I have a YouTube channel. It's at Yvon Karney MD.
• 55:15
  Speaker 3: I'm also on Instagram. I have a brick and mortar
• 55:19
  Speaker 3: functional medicine practice in the Chicago suburbs. Anybody in the area,
• 55:24
  Speaker 3: we would love to be able to help you. I
• 55:26
  Speaker 3: have a fabulous team here. And I also want to
• 55:29
  Speaker 3: mention that we have a hormone quiz on our website
• 55:32
  Speaker 3: and I'd be happy to give you the link to
• 55:33
  Speaker 3: that here. And it's a great quiz that you can
• 55:36
  Speaker 3: take to evaluate do you have hormone imbalanced symptoms, and
• 55:42
  Speaker 3: if you're wondering, do I have rusty locks? Because I've
• 55:45
  Speaker 3: been talking about the importance of the cell. If you've
• 55:48
  Speaker 3: got four or more different hormone imbalances, chances are it's
• 55:52
  Speaker 3: rusty locks and not just hormone problems. So if you
• 55:55
  Speaker 3: take my quiz, then we can work with you afterwards
• 55:59
  Speaker 3: in the form of emails to give you some advice
• 56:01
  Speaker 3: on what you can do to help balance your hormones
• 56:04
  Speaker 3: and get rid of rusty locks.
• 56:07
  Speaker 4: Unfortunately, we lost our power here in Tiberan, California, and
• 56:11
  Speaker 4: I had to let doctor Carney finish answering the question
• 56:17
  Speaker 4: I had asked her, and I understand from.
• 56:19
  Speaker 1: The follow up that she did do that. So I
• 56:22
  Speaker 1: just wanted to say thank you so much.
• 56:24
  Speaker 4: For doctor Carney for being so informative, and I hope
• 56:29
  Speaker 4: this was really helpful to a lot of the women
• 56:31
  Speaker 4: that are viewing my podcast, so I know it was
• 56:34
  Speaker 4: helpful to me to hear her viewpoints on all these
• 56:39
  Speaker 4: subjects that relate.
• 56:40
  Speaker 1: To our hormone health.
• 56:41
  Speaker 4: So I just want to wish everybody a wonderful day
• 56:45
  Speaker 4: and we'll be back soon.
• 56:48
  Speaker 1: Take care, Bye bye.