485-Clinical Translation of Fertilo for In Vitro Maturation

Paper Talk · Feb 8, 2026 · 17m

Researchers developed Fertilo, a clinical-grade product using hiPSC-derived ovarian support cells to improve in vitro fertilization. By mimicking the ovarian microenvironment, it enhances oocyte maturation and pregnancy rates. Phase 3 trials confirm its safety and efficacy.

References:

Paulsen B, Barrachina F, Piechota S, et al. Development of human induced pluripotent stem cell-derived ovarian support cells as a clinical-grade product for in vitro fertilization[J]. Cell Stem Cell, 2026.

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