137-The Expanding Vistas of Spatial Transcriptomics
This review article discusses the rapidly evolving field of spatial transcriptomics (ST), which enables the quantification of RNA across the transcriptome within intact tissue sections, overcoming the historical trade-off between broad biomolecule measurement ('-omics') and targeted localization (e.g., immunostaining). The authors categorize ST into two main methodologies: sequencing-based ST (sST) and imaging-based ST (iST), detailing the technological advancements and workflows for each approach. The text highlights three key biological questions that ST technologies are best suited to…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.