Latest / Ageless and Timeless Podcast® / Christian Drapeau, pioneer in Adult Stem Cell research
Transcript
- 0:10Good morning everyone. This is Michelle Hughes from Ageless and Timeless. Today I
- 0:14have another very special guest. I know I say that it really but today
- 0:19I want you to meet someone that I've been talking to for several months.
- 0:23We've had a little bit of adjusting of schedules to get together on this podcast.
- 0:27But his name is Christian Prepo and he's from Canada. And although Christian,
- 0:34you do go back and forth to the United States from Canada, right,
- 0:39I try to live in the United States now for almost thirty years.
- 0:42Oh oh, well that I'm guess I'm behind the time. Well, you
- 0:45know why I thought Canada because I tried to reach you when you were in
- 0:49your at your cabin there you go. I do go back to Canada.
- 0:52That is in Canada. So yeah, So where exactly do you live in
- 0:56the US? In Austin, Texas. Oh you're another man? Okay,
- 1:02interesting? Well what made you? I know? Austin is a you know,
- 1:07is another high tech hotded. So is that why you went there or
- 1:11was there another reason that you ended up matriculating from Canada to Texas. Well,
- 1:17I moved from Canada to Climate Falls, Oregon, which is where I
- 1:22started to do all the initial work. Then the first product that we put
- 1:26in the marketplace was through a company that we structured in California, which is
- 1:30where I was until moving to Austin. And the company moved out of California
- 1:34and they moved to Florida. But my wife is an actress in Florida is
- 1:38not really a great state for movie making, so Austin at the time,
- 1:42So in twenty fourteen, Austin was a really fast growing city for everything pertaining
- 1:49to cinema. So we decided to go to Austin, and we have not
- 1:53regretted. It's a really great place to live. Oh that's wonderful. But
- 1:57you know, we in California are very concerned by the number of people that
- 2:01have left are leaving California at for Texas and Florida and Nevada and other places.
- 2:07But I mean, I suppose there as many people coming in as still
- 2:14that makes the state viable, but just to see the kind of departures,
- 2:19and a lot of it has to do with California's politics, I'm afraid to
- 2:23say. We won't get into that today, but let me just tell everybody
- 2:27a little bit about you, and then I'm going to let you take over
- 2:30because we have an amazing podcast today. We're talking about a subject that everybody
- 2:37that is in the health and wellness world wants to know more about because it's
- 2:40actually quite a new subject, relatively speaking, and that's stem cells. And
- 2:46those of you who have studied stem cells will be fascinated by all that Christian
- 2:52has done to advance the stem cell research. And he's written a book called
- 2:55Cracking the Stem Cell Code, which Tony, I don't know if you have
- 3:01that website, but maybe you could flash during the podcast today you could flash
- 3:06a copy of the book if you don't mind. But anyway, So Christian,
- 3:10you started out as a neuro physiologist and you were research. Your research
- 3:15was all done in Canada with McGill. Correct correct. I was at the
- 3:20Montreal Neurological Institute, right. That's that's a pretty into this famous institute and
- 3:27has a lot of credibility in the brain research world. So what led you
- 3:32to go from brain research to stem cell research? Well, it was really
- 3:39I was hired. So my background was or my research was on epilepsy and
- 3:45memory. Uh, and then along the way I came across a company that
- 3:49was selling a blue greenology which is blue Greenology from climat Late and they were
- 3:53selling this product and one of the main benefits was an increase in mental clarity,
- 3:59increase in sort of a sense of mental energy, concentration focus. And
- 4:03I must say that before all of that, in my teens, I had
- 4:08developed ways of learning, fast accelerated learning methods that I had applied and it
- 4:13made it easy for me to speak about a topic, a scientific topic,
- 4:16and really make it simple. So it was an interesting package for that company
- 4:21to bote lecture for them and their customers, but also to do the research
- 4:27product. So that's really why I was hired. I was hired by this
- 4:30company in Oregon. That's my move from Canada to America. So I moved
- 4:35to Climate Falls to study that plant and establish or document its mechanism of action.
- 4:43So this was right after the passage of the Shay. So after the
- 4:46Shay was passed, companies needed to have science to back up any claims that
- 4:49they were making on their product. So I was hired to do that.
- 4:53So we quickly identified its benefits on inflammation, on immunity, on mental clarity.
- 4:59But as I'm working with this plant, I came across people who reported
- 5:04really great benefits on conditions like multiple sclerosis, heart problem, diabetes, kidney
- 5:10failure, liver failure, parkinson, COPD, andmphysema. And so the question
- 5:15to me was, what is this product doing to bring benefit to the heart,
- 5:19to someone's heart, someone else's liver, pancreas, lungs, brain,
- 5:25joint, skin, and so on. There was no understanding of how a
- 5:29product could do so many things in the body. So we did research for
- 5:32a few years. And it's only in the early two thousand, like two
- 5:35thousand and one where I came across an article the title was turning Blood into
- 5:40Brain. It was the first documentation to my knowledge, of a stem cell
- 5:45going from the bone marrow going to the brain and becoming a brain cell.
- 5:48We need to position ourselves back into two thousand and one. At that time,
- 5:53stem cells are only known to be precursors to blood cells, and of
- 5:57all new cells in the bioll new organs. The brain we know does not
- 6:01repair, does not regenerate, at least that's what we were told at the
- 6:04time. So an article showing that a stem cell was going from the bone
- 6:08marrow to the brain, I thought was an amazing breakthrough. So I dug
- 6:12a little bit more in the scientific literature found similar articles documenting stem cells going
- 6:17to deliver into the heart and becoming liver cells and heart cells. So I
- 6:21thought, so we're back in two thousand and one. I thought, if
- 6:25stem cells can become heart, liver, and brain, why not pancreas,
- 6:28long skin, and the rest. It makes no sense that it would become
- 6:30those three and of the rest. And if they do become all these cells,
- 6:34then they have to be the repair system of the body. And in
- 6:38the back of my mind, the thought was, if stem cells are the
- 6:41repair system of the body, what if a plant were to trigger the release
- 6:45of stem cells, they would go to the pancreas of the diabetic, the
- 6:48heart of the heart patient, the brain of the parkings and patient, And
- 6:51we should expect a broad variety of benefits. And that's what we add with
- 6:55AFA. So that's how it all started, the thought that what if this
- 7:00lubrinology worked by triggering the release of stem cells from the bone marrow. So
- 7:04we acquired the equipment to count stem cells and very quickly discovered that that's how
- 7:10that plant was working. So everything I did stopped and I shifted everything all
- 7:15my activity into the field of stem cell research. So that's how I became
- 7:18involved in the field of stem cell research. So Christian, the clury potency
- 7:24issue has always been a question and kind of the miracle of stem cells that
- 7:29how could a cell have a brain stem cell to know where to go when
- 7:33it gets into the body, that it goes where the most versus most needed,
- 7:38where the repair is most How find that to a lay person that a
- 7:44stem cell can be plury potent. Okay, let me just before I answer
- 7:48your question different directly put that into a greater context, because I think it
- 7:54will help make this answer easier. We look at by we, I mean
- 8:00population in general. We look at stem cells as a new discovery, cutting
- 8:05edge science, new treatments. How could stem cells do this or that?
- 8:09And what we need to understand is that this is coming from the fact that
- 8:13we're just learning about it. Stem Cells have been there for as long as
- 8:18we've been humans, and they're there since the day we are born. They
- 8:20are your repair system. They have done like you will never ask that question
- 8:24when you have a cold and you say, how can the immune cells go
- 8:28to my lung and magically kill viral infected cells? It's not magical, it's
- 8:33what they do. It's their role. Stem cells do exactly the same thing.
- 8:37They are the repair system, and that's what we need to understand.
- 8:41What is new is that we didn't know about this before. And the more
- 8:43we dig, the more we find ways to tap into the regetative power of
- 8:48stem cells. But it is our repair system. So the way that they
- 8:52can become that they're pluripotent is just because it's their nature. We all started
- 8:58from one cell dosz igo, which is the sperm in the egg that makes
- 9:01the one cell that is the ultimate stem cells that has become the entire U,
- 9:07the entire us. So that was more than pluripotent. It was totipotent,
- 9:11meaning it can become everything. And as we develop after birth, we
- 9:16are left with these stem cells that are no longer toty potent, but they
- 9:22are pluripotent, meaning that they can become almost everything or a lot of things.
- 9:26And then as they progress in their transformation, not in our lives,
- 9:30but as the life of a stem cell, then it becomes more multipotent,
- 9:33meaning they can do many things, but it's more restricted. Then they become
- 9:37progenitor cells as they get into a tissue. Now they become stem cells of
- 9:41that tissue. But at the origin in the bone marrow, they are pluripotent.
- 9:45It is their role and they will find where to go because they will
- 9:48be attracted by an injured tissue as this tissue is releasing inflammatory compounds SOS compounds.
- 9:56These compounds called stem cells to that tissue, just like an infected tissue
- 10:01will call for immune cell the same mechanism. Mm hmmm, So how do
- 10:05you how do you define the difference between a stem cell and an immune cell
- 10:09or a regular cell. Eye, Every every cell of the body is referred
- 10:16to as a somatic cell. Sola means physical matter. So it's it's a
- 10:22it's a it's a cell of your body. It's the cell of your heart,
- 10:24and it does one specific thing. It contracts a cell of your retina,
- 10:28It responds to light, a better cell of your pancreas makes it insulin.
- 10:31Every cell as one specific function. It has a very specific physical structure.
- 10:37We can recognize them under a microscope and they will never transform to become
- 10:41something else. A stem cell is nothing. If you look at it on
- 10:46the under the microscope, it looks like an immune cell. You cannot really
- 10:50identify it its identity. Why what makes it a stem cell is that it's
- 10:54the only cell in your body. Then if you put it in the context
- 10:58or in the environment, let's say of a liver, it will become a
- 11:01liver cell. You put it in contact with heart cells, they will transform
- 11:05into heart cells. You put them in contact with the skin, they will
- 11:09become skin cells. So they will become any type of cell types in which
- 11:13they find themselves. So as they leave the bone mettal as a stem cell,
- 11:16their faith is to travel and then to enter into a tissue where they
- 11:22will become cells of that tissue and will be part of the repair or the
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- 12:28So apoptosis, does cell turnover happens? They say every seven years? Right,
- 12:35So what you're born with is not going to be the cells that you
- 12:39have when you're thirty years old. So how do you explain how stem cells
- 12:45come to the aid of apoptosis to be there for you as you age.
- 12:50Very very good question, because what you just mentioned was a reality that was
- 12:56sort of like a deep, deep common sense, but there was not a
- 12:58lot of science wrapped up around this idea that you know that you change every
- 13:05seven years. What stem cell research has revealed is that the seven years in
- 13:09itself is not correct. What is correct is that there is such a thing
- 13:13as tissue turnover. We lose cells and we replace them, and there's this
- 13:18turnover. The reality is that every single organ in tissue will have its own
- 13:22turnover rate. You get a new liver every two three years, and you
- 13:26pancreas forty six years, and new skin every month, half of a new
- 13:30heart every twenty five years. The entire body is constantly in the process of
- 13:35turnover. Apoptosis is a phenomenon of let's say, cellular suicide. It's part
- 13:41of the genome of a cell. When a cell reaches certain characteristics, certain
- 13:46criteria that are the characteristics of a cell that is too old and is becoming
- 13:50dysfunctional, it triggers or cancerous. It triggers that process and it commits suicide,
- 13:56so it takes itself out of the cell, sorry the pool of cells.
- 14:01So that's what is a poptosis. So the real life of a cell
- 14:05is that it comes as a stem cells leaves the bone marrow, migrates into
- 14:09a tissue like the liver, then becomes the stem cell layer of that liver
- 14:13that they proliferate in the liver. They're called oval cells. These are the
- 14:16stem cells of the liver, and then they provide new liver cells to that
- 14:20tissue that will live their life as liver cells, which is about two three
- 14:24years in the liver, and at the end of their life they trigger a
- 14:28poptosis and then they disappear from deliver and you have this constant renewal process taking
- 14:33place in every single organ and tissue of the body. And where that is
- 14:37super important is to realize that we are born with red marrow that makes stem
- 14:43cells, but the red marrow converts into yellow marrow or fatty marrow that does
- 14:48not make stem cells very early in life. By it's thirty, we have
- 14:52lost ninety percent of our red marrow and that coincides with a ninety percent decline
- 15:00the number of stem cells in circulation, Meaning there's a point in our thirties
- 15:03when we all discover we're no longer Wonder Woman Superman. We don't have enough
- 15:09stem cells to offset this normal process of seilar loss. And that's when we
- 15:13start for the first time in our lives to think about aging, because now
- 15:18we experience it. It's from that point on, and aging from that point
- 15:22on is to a large extent, caused by this decline in the number of
- 15:26stem cells available to maintain our tissue. Does that answer your question? Yes?
- 15:31So is that pretty standard? I mean, or is there a rate
- 15:35of cellular sinessence that varies based on the lifestyle of the person or the You
- 15:41know, obviously, if you just put one fact of chronological age, but
- 15:45what about all the other factors do they affect the rate of cellular sinessence that
- 15:50might somebody might be in their forties or fifties and still have many more stem
- 15:56cells than someone who's in their thirties. Yeah, I mean these are two
- 16:00questions. So the number of stem cells is one thing. Sinessence is something
- 16:03that is different. But we are kind of early in the study of sinescence,
- 16:08not so much in the physiological reality of sin essence, but in what
- 16:12we're doing in our life in terms of lifestyle to affect sinessence, accelerate it,
- 16:18make it more important or eliminated. So we know today we know as
- 16:23of today there are compounds referred to as synolytics that are going to help these
- 16:30sinescence cells, like these cells that are old that should trigger up of poses
- 16:33but for some reason do not. Then they become disregulated and they're sort of
- 16:38negative cells for their environment. So there are ways of making these cells trigger
- 16:42up of poses and kill themselves. But there is a whole discourse, and
- 16:48I remember maybe ten years ago in French there was this idea that was developing
- 16:53and scientists were saying, well, antioxidants are good, but you could take
- 16:59too many, too more or too many antioxidants. I thought the idea was
- 17:02kind of a little strange. But now with all this emergence of all this
- 17:07science about sinroolytics, there is an interesting question as to when we provide too
- 17:11much protection for the body. Do we somewhere across a line where we protect
- 17:18these aging cells and provide them with enough nutrition to kind of continue to live
- 17:23in that sinescent cells and it's actually not positive. So there are things that
- 17:27we can do. We know exercise helps sines and cells to get away.
- 17:33And there's also autoplogy that comes into this whole process when an aging cell has
- 17:37the capacity to kind of rejuvenate by cleaning itself within and that is something that
- 17:44is taking place during fasting. Or we have discovered now that there are compounds
- 17:48like spermidine for example, and others that are going to trigger the process of
- 17:53autophagy in the cell without adding to fast So all of these can affect a
- 18:00stem cell that has penetrated a tissue and now become cells of that tissue and
- 18:04it starts its process of aging in that tissue as the stem cells themselves in
- 18:11the bowl marrow. The conversion of red marrow to yellow marrow. It has
- 18:17been known for a long time, but its significance in longevity and aging is
- 18:22a very very novel understanding. So I am not aware of any research that
- 18:27has been done to either determine what things that we do in our life,
- 18:33lifestyle, or exposure to certain components of the air, water, whatever that
- 18:37could affect the rate of conversion of the red marrow. So I'm not aware
- 18:42of that. I'm not aware of any compounds that have been studied for their
- 18:45ability to do what it's called reconversion going from fatty marrow and regrow the red
- 18:52marrow. There's one big warning is that when we see normally something called reconversion
- 18:57that your red marrows, normally, this is linked to leukemia. So so
- 19:03somewhere this concept of trying to create reconversion and graw a red marrow, lots
- 19:08of research would have to be done and safety trials would have to be done
- 19:12to make sure that that can be that can be achieved with safety. But
- 19:15if there was a way of really making red marrow re expand, it would
- 19:22probably I think be the single most impactful thing that we could do for longevity.
- 19:26The really important point that you've just made and I don't think you know.
- 19:33I would be interested if David Sinclair and Harvard was his riz vera trial
- 19:37and his snalytics, whether he would be going down that path in his research.
- 19:42Have you heard anything about anything going on there with him taking a lead
- 19:48in senalytics. Okay, well not yet, not yet. I'm still yet
- 19:52to meet David Sinclair. But I'm sure we can have a great discussion about
- 19:56it, because because what we do have a lot in common, although they
- 20:00belong to completely to different fields. And what I mean is that when a
- 20:03stem cell gets into a tissue, that stem cell will become five to ten
- 20:08thousand tissue cells. So a million stem cells that migrates in a tissue that
- 20:14has an injury, which is total, which is reality. If you release
- 20:18let's say ten million stem cells with some of the herbs that we have a
- 20:22norbal extract that we're working with, these are out of these ten millions,
- 20:26a million could very well migrate into an injured tissue and then become a billion
- 20:30tissue cells, five billion tissue cells. So when that happens, the magnification,
- 20:37the amplification taking place in the tissue costs an enormous amount of energy.
- 20:41Number one. But all these new cells need to have mitochondria. So the
- 20:45expansion of healthy mitochondria well equipped to do what new cells are doing, really
- 20:55is totally needed by these cells. So anything touching NMN and anything supporting mitochondrial
- 21:00function will have a big impact in supporting these new stem cells. So somewhere
- 21:04it's extremely complementary. Yeah, so you're what you're saying is, if you
- 21:07know, it's one thing to to mobilize from the bone marrow, it's another
- 21:12thing to migrate successfully into the tissue and to have an environment that's welcoming rather
- 21:18than destructive, because a lot of people have cells and their tissues that are
- 21:22are not welcoming the stem cells. So I don't know if that's kind of
- 21:30a simplistic way of saying it, but I think the difference between mobilization and
- 21:33migration and then acceptance there would be three levels right of the stem cell integration.
- 21:41How about question how do you measure? How can you count? Is
- 21:45there any kind of a test that a person how many stem cells they have
- 21:51any one time in their body? Yes, there's a sorry, go ahead,
- 21:56Well it's gonna say YEA. I was going to say maybe different between
- 22:00in the bone marrow versus in the tissues. There is because those are two
- 22:04very different counts. Right, how many are sitting in the bone marrow waiting
- 22:10to be mobilized and how many are in the tissues being utilized by the body
- 22:14to heal and repair. Yeah, to do a stem cell count in a
- 22:19tissue, in a human tissue, I'm not going to say it's not possible.
- 22:22It is possible, but it is a biopsy and this very specific area
- 22:27of the tissue. So to quantifye themselves in a tissue is not a simple
- 22:32matter, and I'm not aware that it is done clinically at this point.
- 22:36You can do it from the bone marrow, so that will be a bone
- 22:37marrow aspiration and that is done. We're doing a study right now on our
- 22:42product'stmorag and specifically to see its impact on the population of stem cells in the
- 22:48bone marrow. So, but once you did the aspiration or you take a
- 22:52blood sample, the technique to quantifytem cells is the same, which is basically
- 22:57the use of a flos automata. The traditional means is still usable, which
- 23:03is to plag them put them into a pittri dish and grow them in specific
- 23:07medium that will make stem cells grow. And then as you count the colony
- 23:11that are being formed, you can count the number of stem cells. But
- 23:14it's tedious and it's not as precise as the novel technology, which is flow
- 23:18cytometer. It is a machine that that aligns cells one behind the other into
- 23:23a very fine tube and as they lined up, they go in front of
- 23:27a laser and that laser will shed light of different colors and will illuminate these
- 23:33cells. And if you first attached to these cells different antibodies for markers of
- 23:38stem cells, markers of cells that are not stem cells, so it allows
- 23:42you to exclude those that are not stem cells. Then you can count the
- 23:47cells that meet all the criteria for being a stem cells and you count them.
- 23:49So that's the technique that is used with flow cytometry. That's what we
- 23:53have used in all of our studies. The problem is that that device is
- 23:57normally used in cancer treatment, so you will not find this at your doctor's
- 24:03office. You will not find this at any if you're going to have a
- 24:06normal blood sample taken for what is normally done in terms of blood tests,
- 24:11then they will not have the technique to be able the method or the equipment
- 24:15to be able to do stem cell count. I'm working on developing this machine
- 24:18right now. We're very close, So give it maybe another year and we
- 24:22may have a way fairly cheap to be able to quantify the number of stem
- 24:27cells in the blood. But when we have this technique, there's another layer
- 24:30to this. It's to understand that it is a very very small population of
- 24:36cells in your blood. And the problem is that if you just sneeze,
- 24:40for example, and you squeeze your spleen, you will change the proportional population
- 24:45of your immune your lymphocytes, and your blood. You're not going to change
- 24:48a many stem cells you have, but you're going to change your statistical power
- 24:53in counting these stem cells. So my point is that it's not a simple
- 24:57task count themselves. So I don't know when it is that we will have
- 25:02a way where somebody can go in to live and just say tell me how
- 25:03many stem cells I have in my blood and I can rely on that one
- 25:08test. So it's not done yet. It's not that advanced yet. But
- 25:14you know, because five years, ten years ago, you wouldn't have been
- 25:18able to test your telemere lanes, or your DNA methylation, or your intrinsic
- 25:26versus extrinsic age in biological aging versus chronol. I mean, all these things
- 25:30are I know, I've heard you say this and I couldn't agree with you
- 25:34more that, and I've said it many times on my podcast. In the
- 25:38last ten years there's been more advancement in medicine than the last hundred years.
- 25:45And if you step forward with AI and the other technologies that are becoming much
- 25:52more widely available, imagine what the next ten years will be like. I'll
- 25:56bet you that that will be readily available for not I mean, I just
- 26:02wonder aloud with you, is it valuable information to have as a as a
- 26:08practitioner what you know? And I know you're the on the research side,
- 26:12but developing products nutraceuticals to support your research. So do you think it's valuable
- 26:18for anyone to know? People to know other than people who have a serious
- 26:23illness, to know what their stem cell count is, just like they know
- 26:27what their blood you know certain blood markers are. I have absolutely no doubt
- 26:33in my mind that as this is more developed and people reach a greater understanding
- 26:40by people, I mean the medical community reaches a greater understanding of the role
- 26:45of stem cells and health and wellness and disease formation, that the number of
- 26:48stem cells in your bloodstream will become probably the single most relevant measure to know
- 26:56not necessarily your longevity, but how well you will live in the years to
- 27:00come. And I'm saying this because let's go back for a moment to what
- 27:03I was talking about before. As you pass thirties, the number of stem
- 27:07cells in your bloodstream declines significantly, so you don't have enough stem cells to
- 27:11offset sellar loss. If we understand that, then I published this about ten
- 27:17years ago in the scientific literature as a hypothesis, and the hypothesis was we
- 27:22develop diseases because if you think about it, every single degenerative disease is the
- 27:26loss of a type of cells. If you have diabetes, you lost the
- 27:30cells making insulin. If you have Carriomiopathy, you're losing muscle cells in your
- 27:34heart. You have parkinson you're losing cells making dopamine in your brain, and
- 27:40you go like this, to almost any diseases, it's always the loss the
- 27:44type of cell or a loss of function of a type of cells, so
- 27:48that means that from the moment you don't have enough. Oh something happened with
- 27:56your camera, Christian, can you hear me? Mm hmm, Tony true,
- 28:11Okay, we lost you. We lost you for about a nano minute
- 28:14here, Okay, yeah, but go ahead. I think it'll be okay.
- 28:19Okay, I think do you have the recording because I think I saw
- 28:22what I started to freeze? Do you want me to go back a little
- 28:25bit behind. Yeah, we can edit, so okay, Yeah, so
- 28:27you go ahead and just keep it. Okay. So the idea was,
- 28:32let's go and count the number of stem cells and the blood stream of people
- 28:34who have developed various types of age related diseases, and let's compare that with
- 28:41healthy people of the same age. And now there's a number of studies that
- 28:44have been done. If you count the number of stem cells in the blood
- 28:47stream of people with diabetes, at the roscrosis, art disease, copd,
- 28:52erectile dysfunction, liver failure, kidney failure, lupus, arthritis, Alzheimer's,
- 28:57parkinson and the list growing. Every time one of those studies is done.
- 29:03The result is always the same fifty percent or less in the number of stem
- 29:08cells in circulation when compared with healthy people, meaning you have developed the problem
- 29:15because for one or two decades, every day you just did not have enough
- 29:19stem cells to offset ceterular loss combined with lifestyle that probably accelerated ceter loss.
- 29:26So the moment we understand this, it means if you can put more stem
- 29:32cells in circulation every day of your life, you repair better, you maintain
- 29:36your tissue better, and you maintain the hell that you have today for the
- 29:40decades to come. So it will become i think, the most important parameters
- 29:44to predict whether in a decade or two from now you will be healthy.
- 29:49And that's really another very important point because affordability if we take a stem cell
- 29:56injectables versus the oral which which you so generously have done the research to create
- 30:03for humanity, which we'll talk about in a moment, But if you take
- 30:07the injectibles, they're very expensive, they're not really affordable for most people.
- 30:12And yet if you just kind of assume that, Okay, after thirty you're
- 30:18going to have fewer of the right the red marrow stem cells, you need
- 30:22to continue to improve that number those that count to have them be more efficacious
- 30:30for repairing the in the body in the tissue. So if you say that
- 30:33and you just kind of assume, like with heavy metals, I just assume,
- 30:37why do I need to take a heavy metal test? Because I know
- 30:40everybody has heavy metals, So why don't I just start treating for heavy metals
- 30:44and forget the test. But I think you can pretty well assume with what
- 30:48you're saying that most people I mean healthy can mean yes, you have more
- 30:52stem cells available to repair the tissue. However, you still may need more
- 30:57stem cells to move forward into aging, so why not just get them?
- 31:02But the availability part and the affordability part, I think are the big stop
- 31:07gaps. So that brings me to the very important point of stem regen,
- 31:12which is the product that you've developed and is now available to the wide range
- 31:21of humanity that wants to increase their stem cells. So contempt me just tell
- 31:26us how that product came about, and if you could incorporate your experience at
- 31:33Klamath with the development of stem regen and how they morphed into that becoming the
- 31:41product that actually turned the tide for you, and there's a big, big
- 31:45change in your life. But yet a lot of what you did at klamath
- 31:48is now reflected in the stem regen product. Does that make sense what I'm
- 31:53asking? Absolutely? Absolutely? So, as I was talking about this blue
- 31:59greenology, we discovered that it was acting as a stem cell mobilizers, putting
- 32:02more stem cells in circulation. If we go back in two thousand and one,
- 32:07two thousand and two, and all that work was done coming out with
- 32:09a message to say we have found a plan that is putting more stem cells
- 32:14in circulation. I mean, without an exception, every single scientists were responding
- 32:20to this by saying it doesn't mean anything. More stem cells in circulation doesn't
- 32:23mean anything, and maybe actually maybe it's bad for you. So there was
- 32:28and then if you don't have a mechanism of action, maybe it's just random.
- 32:30So we had to go into identifying the mechanism of action, the active
- 32:35compound proof of concept, and then the literature that was developing at the time
- 32:40really brought all the data needed to say, yes, more stem cells is
- 32:45better. So that took a number of years. We launched that extract itself
- 32:50in two thousand and five. But what I continued to do is that for
- 32:52me, it was clear the moment that we find that a plant as an
- 32:57effect on stem cells, there has to be other plans we evolved in same
- 33:00uses with the environment. Let's go back to what I was talking earlier on
- 33:06the overall context is to understand that stem cells are simply the repair system of
- 33:09the body, just like you have an immune system. We just discovered the
- 33:14body as a repair system. So just like you don't have one single plant
- 33:17in the whole world of plants having an effect on the immune system, there
- 33:22has to be other plants, So how do we find them? So I
- 33:25simply asked the question, just like the observations that we had on afa,
- 33:30which is a plant that is bringing many, many different types of benefits,
- 33:34and we discovered it because it has an effect on stem cells. Then we
- 33:37started to look at other plants known to have many, many benefits. So
- 33:42we looked at medicinal mushroom, gojiberry associated with longevity, some seaweeds, astragglers,
- 33:47things like this that have been known oftentimes as adapto gens, meaning they
- 33:52bring a lot of goods for you, but we don't know how they work
- 33:55well. All of them. They have an effect on stem cells. But
- 34:00the big discoveries is when I went into remote areas of the world. Like
- 34:05when I had a chance to go to Madagascar, Papua New Guinea, I
- 34:07didn't go, but colleagues of mine went there. So from these regions Papua
- 34:13New Guinea, the Congos, South America, what are they using there outside
- 34:17of the global economy, What is their go to plant for many times of
- 34:22health problems? And that's where we found very interesting plants. Like in Madagascar,
- 34:29they have about sixty five species of alo, but there's only one that
- 34:31they have used for centuries to make a product called Vahona, which they use
- 34:37for all kinds of health problems. So Vawona is made out of one species
- 34:40of alo called Alo macroclata. So we tested it and we got so far
- 34:45the strongest response that we have ever had. But it's not a product that
- 34:50exists in the marketplace. So for that one, we had to develop our
- 34:52own system of collection harvesting by tapping into the Malagasy populations and then we set
- 35:00up a manufacturing plant. So now we have our own system to collect alomcroclata.
- 35:06And then we also discovered on the Tibetan plateau alomcroclata sorry seabuktone berry utilized
- 35:14for centuries, if not millennia, with in Tibetan medicine, Mongolian medicine,
- 35:19traditional Chinese medicine. It has been used for problems of the luan of the
- 35:22heart, cardiovascular system, function of the pancreas, and to help people repair
- 35:28from broken bones or burn to the skin. When you look at the spread
- 35:31of these benefits, to me, it's telling me it's likely that it has
- 35:35an effect on stem cells. So we derived an extract in collaboration with a
- 35:39company they're harvesting on the Tibetan plateau, and we documented that it acts as
- 35:45a stem cell mobilizers. It needs to be seabuctne berry grown at high altitude,
- 35:51and in this fashion we also owned in Notogensen, the original Gensen.
- 35:55We know Gensen has been documented for centuries for so many benefit, so many
- 36:00different types of benefits. We found that Notrogensen puts more stem cells in circulation.
- 36:06And the last one is fichoidan, which is a polysaccharide coming from brown
- 36:10seaweeds. It has been used for centuries for all kinds of benefits, but
- 36:16the one we're utilizing the one from fucus. Because we can also extract from
- 36:22fucus fluorotanins where has also been associated with longevity and health and repair of the
- 36:29nervous system. So we were using a fiicoidan fluorotanin extract from fucus. So
- 36:35these are the top five plants that we have studied over the years, and
- 36:38we have included in stem regen, where you take two capsules of stem regen
- 36:43and you will release an average of ten million of your own stem cells.
- 36:47Okay, So what happened to the blue green alergy while was that not included
- 36:52in the stem regen if that was where you start it is it is?
- 36:57So it's stem regen seaboctone berry almada, notrogensen in the fugus extract. Okay.
- 37:02So if you're taking blue green algae or you're doing green drinks, that
- 37:08only enhances what you're already getting with the sem regenda, right that which will
- 37:14be you would have to take five grams of it to be able to get
- 37:17the effect of what we have in stemagen. So it's it's totally doable.
- 37:22Okay. So what about the person who wants to get the extra bang for
- 37:28the bug and has the extra availability of the monetary side. What about combining
- 37:37the injections with the sem regenda. Have you done any research on the effects
- 37:42of the two together versus one each one by itself. Yeah, we have
- 37:47done. Actually it's ongoing. It's a research that is ongoing right now,
- 37:51and it came from the fact that the idea of doing it came from a
- 37:55colleague of mind in. He's a cardiologist in Madrid and also in Miami,
- 38:00and I've been working with him for many years a decade and then he would
- 38:06typically do stem cell injection and then use stem reygen with the stem cell injection,
- 38:10and he historically he gets much better results than his colleagues, and oftentimes
- 38:15when he mentions that to his colleagues, they don't believe it because it's hard
- 38:21to believe that these two simple capsules can have that kind of impact on health
- 38:25and recovery. So we decided to just document that in a study. So
- 38:30we have an ongoing study right now where we study congestive art failure. So
- 38:35the patients, the participants all have stable chronic congestive art failure. They are
- 38:38treated with all the typical treatments that is being provided to these patients, and
- 38:44then we simply add on top of this either stem reygen alone or stem cell
- 38:49injection or a combination of both. And the idea was to be able to
- 38:52compare how stem regen compares to an injection, but also what benefits do you
- 38:58get by combining both. And it's ongoing, so we have preliminary data on
- 39:02ten of these participants, and what we can share is that of these ten
- 39:08participants, all of them have seen significant improvement in cardiac function to the point
- 39:14where after six months their heart function is pretty much normalized. When we compare
- 39:19that with stem cell injection, they get slightly better results, but when we
- 39:22combine the both stem cell injection and stem regen, they get much better results.
- 39:27So really what is coming out of that study? And it's ongoing,
- 39:30so we will publish all the data and when it's final. I'm working right
- 39:34now and publishing these preliminary data. But it pretty much says if you can't
- 39:37afford stem cell injection, then it will be foolish to not add stem regen
- 39:42with it. And if you can't afford stem cell injection, then tapping into
- 39:46something that can release your own stem cells put more of your own stem cells
- 39:51in circulation already enhances your inaability of repair enough to bring you significant benefits.
- 40:00Christian, what is the difference between the umbilical and the embryonic or embryonic and
- 40:05then the adult stem cells. I know there's a lot of controversy. People
- 40:08don't understand the difference. Most you know, most people think that the best
- 40:13thing is to get the umbilical because that's the baby stem cells that haven't matured
- 40:16and they're much more effective. So can you just explain those those terms to
- 40:23people to yes, the the embryonic stem cells are not really a thing.
- 40:30I mean, there's there are a thing on the research side. On the
- 40:34treatment side, uh, they are too wild as stem cells, if I
- 40:37put it into in simple terms, and they have too high of a risk
- 40:42of developing tumor form creating tumor formation, so they're not reutilized. So that's
- 40:46not really an option in the marketplace. So the main options will be umbilical
- 40:52cord stem cells or adult stem cells. And adult stem cells can come from
- 40:54your blood, your bone marrow, or from your fat tissue. Umbilical cords
- 41:00stem cells are also adult stem cells, so the difference between the two.
- 41:04And let me preface this by saying that you will find people who will only
- 41:09swear about umbilical cord stem cells and they'll tell you they're the best, and
- 41:15then the rest is really not valid, and you have other people will tell
- 41:17you the best is fat derived stem cells much better than umbilical stem cells,
- 41:22and they will only pitch sort of that side. Let me try to be
- 41:25as objective as I can, because it doesn't matter to me. I'm not
- 41:29in that in that industry. The advantage with umbilical cord stem cells is to
- 41:35understand that stem cells age in your body. So if you let me just
- 41:40share a study, for example, done in mice. If you take a
- 41:43relatively old mouse, let's say a ten month old mouse, and you trigger
- 41:47an injury in that animal. And if you take stem cells from an old
- 41:52mouse and you inject those stem cells compared to stem sales umbilical cord stem cells
- 41:58from a mouse or from a very young mouse, you will get much better
- 42:00repair with young stem cells. So young stem cells are more effective. From
- 42:07that, there is an idea that developed on the marketplace, I mean in
- 42:10things like for example, Tony Robbins's book, where the message that they're conveying
- 42:15is that past forty years of age, your stem cells are worthless and therefore
- 42:20you need on bilical court stem cells. This is entirely false. There is
- 42:23no truth to that. There's a truth to the fact that they're not as
- 42:27good as when you were two years old, no question about it. But
- 42:30the study that I just talked about on congestive art failure that populations are men
- 42:37and women between the age of sixty eight and seventy six years old, and
- 42:40after six months just of releasing their old stem cells, they have recovered normal
- 42:45heart function. So there's no truth to that they are less effective, but
- 42:51they're still very effective. So the argument against onbilical court stem cells, it
- 42:58is a weaker and weaker argument as we move forward. But it is the
- 43:01fact that as you inject or as you isolate umbilical cord stem cells, they
- 43:07come from a different individual. So you rarely have something that is one hundred
- 43:13percent just one thing. You always have some impurities. So these impurities,
- 43:19they are foreign objects in your body, foreign bodies, so your body can
- 43:23react to them. And we still don't know in ten, fifteen, twenty
- 43:27years down the road, are you going to slowly develop some form of portu
- 43:31immune problem or super slow grade rejection, That is that could be the source
- 43:37of a problem in the future. As we move the probability of this is
- 43:42going less and less because we don't seem to see that emerging. But we
- 43:45have not done this long enough to be certain about it. So that is
- 43:49one. The other one is that you are now bringing genetic code from another
- 43:54person, which can have positive and negative effect. Positive meaning that it brings
- 44:00diversity into your gene pool population if you want so. Now you've seated your
- 44:05bone marrow with cells that have the different genetic material, and if anything,
- 44:09it could complement and make you stronger. But if you have genes in there
- 44:14that are prone to tumor formation, for example, or other sort of deleterious
- 44:19effect in your body, now you start to have that in your body.
- 44:22So these are the arguments against some bilical cord. I think that at the
- 44:25end of the day, they don't amount to a significant risk, So I'm
- 44:30not saying don't do a bilical corde injection. But there's an interesting alternative,
- 44:35which is fat derived stem cells. Because the stem cells in your fat tissue
- 44:38are relatively dormant stem cells. So when you take stem cells from your fat
- 44:44tissue, if you are let's say sixty years old. There are not sixty
- 44:47year old stem cells, so that's a nice alternative. And you have plenty
- 44:53of them, so you can extract those stem cells many times in your lives.
- 44:58So it kind of a little bit the idea of making sure you capture
- 45:01your newborn stem cells in case he needs them in his life down the road.
- 45:07Fat stem sales are pretty good. I'm not saying don't do it.
- 45:10What I'm saying is that the cost, like the return of investment of keeping
- 45:15these stales, these stem cells frozen for decades when we don't really know when
- 45:20you really thought them forty years later, are they going to be as effective
- 45:23as your fat stem cells as a forty year old. This is still a
- 45:27question that is unanswered. So in any case, I think fat derived stem
- 45:31cells are just as good. And then you have Booe arrow stem cells that
- 45:37you can aspirate. They're more preypotent your than your fat stem cells, but
- 45:43they have age, not necessarily as much as you, but they have age,
- 45:46and they're not as powerful as a stem cells lit in and what you
- 45:50get from your fat tissue, but they can become everything in your body.
- 45:52So that's kind of the spectrum here so that's why some of the top top
- 45:57clinics. What they will do is that they will extract, they will take
- 46:00a boomeraw aspiration, they will take fat derived stem cells, and they will
- 46:04add to this biblical court stem cells. They make that cocktail and that's what
- 46:07they give you, which is really sort of the the ultimate stem cell injection.
- 46:13And where can you go if you want it? In the United States
- 46:15where stem cells are still heavily regulated? Can you get these injections that you
- 46:22just described here in the US the cocktail that I just described now is done,
- 46:28I believe, I don't know if it's still done. I believe it
- 46:30is still done by the clinic of Harry Hadelsen in Utah. So he is
- 46:36one of the clinics doing that in the country. I'm not aware of another
- 46:39one that does all this cocktail in the country. You can get that easily
- 46:44in Panama and Costa Rica and Columbia or many various clinics have been set up.
- 46:47And that's the kind of approach that they're taking, which is a very
- 46:50effective approach. The approach that we are taking with a project a product like
- 46:54stemmery gen and erbil extract that release your own stem cells. Is that is
- 46:59that you can do this every day. You cannot go and get these types
- 47:02of injections every day. Of course, you cannot even do this every month.
- 47:07Just once a year is already a significant burden for most people. So
- 47:13here you take two capsules and you release ten million of your own stem cells.
- 47:16You can do this every day. After a month, you've released three
- 47:20hundred million of your own stem sales, after a year, you have released
- 47:23essentially or billion of your own stem cells. It starts to be cumulatively a
- 47:29very very significant impact on your body's ability to stay healthy. And then you
- 47:34combine that with doing other things that reduces the rate at which you lose sales
- 47:39good diet and m N good lifestyle, and then I am pretty sure that
- 47:45you can definitely increase your health span very significantly, if not your lifespan.
- 47:52Okay, So I have another question, because I know doctor Todd. You
- 47:57and I spoke about doctor Orikaitis and he's one of my sponsors, and excuse
- 48:02me, and and he mentioned that he trained doctor Edison, I think,
- 48:07and you tell so I had heard about doctor Edison, but he said the
- 48:09price was so you know, out there for treatment that you know, most
- 48:15people wouldn't even be able to consider it. But what do you feel about
- 48:20what doctor Todd and Matria and you know doctor Todd overkitis, what and he's
- 48:25doing in Carlsbad. Yeah, I would, honestly I would. I would
- 48:31need to go and visit him and get more detail about what he's doing to
- 48:36be really real to talk about it. V sales so very small embryonic like
- 48:40stem cells. They are the most potent type of stem cells in the body.
- 48:45They are in a dormant state, they can be in an activated state.
- 48:49Interestingly enough, some of the plants that we have in stem reagen,
- 48:52we have also documented that they also increased the number of these v cals in
- 48:58the blood and also activate a number of them, so they can be activated
- 49:02on their own or at least with plants. But I would need to just
- 49:07know more about what he's doing. I have heard only good things, so
- 49:09there's nothing I can say. But it's hard for me to say anything more
- 49:14because I still have some questions before I can have a full understanding about effective
- 49:19the approach is. So I'll do this. I'll reach out to him and
- 49:22I'll go and visit him. Yeah, I would love to and I can.
- 49:25I mean, you know each other say, I don't need to connect.
- 49:28But when I went there and I did the treatment with him, they
- 49:34took vials of my blood and then they cent refuge that with and then they
- 49:38laser it back into the body and they pick four or five areas of the
- 49:44body that or they ask you, you know, what areas would you like
- 49:49to have injected? So that that's the only thing. I never felt anything
- 49:53different after US. I mean one thing they did say that they did the
- 49:59scene Organs and they said, oh you might you might get your menstrual cycle
- 50:04again, which would be quite shocking. But but I didn't. And so
- 50:10I don't, you know, I never felt anything different. I guess you
- 50:13don't feel anything. You just know that it's doing good for the for your
- 50:16body. But and I had nothing to repair so at that moment in time,
- 50:22so it wasn't like we were trying to do a wound healing or something
- 50:25like that. But yeah, so, I mean he's definitely one and you
- 50:30know that. And then European Wellness, you know doctor Michael Chan from uh
- 50:37Okay, I'm gonna after the podcast, I'm going to send you his contact
- 50:39info. There I think they used sheet though, is that something that you
- 50:45would ever entertain as using stem cells from animals? I would not. I
- 50:51think this is just me okay, But I think that a lot of these
- 50:54techniques, these methods were developed in the early days of stem cell research,
- 51:00a time when we did not understand really the power of the stem cells that
- 51:05we find in the human body. So as we discover really what stem cells
- 51:08can do, then the go to is to go and where can we get
- 51:13them? So we can get them from sheep. I mean, I've heard
- 51:15treatments done with cheap stem cells, fish stem cells, ducts them cells.
- 51:21But the moment that we realize that the human body as stem cells and we
- 51:24can get them from the human body, uh, you know you inject the
- 51:30stem cells from a sheep, that means you have sheep DNA in your in
- 51:32your body. So how really viable are these cells? And is the sorry
- 51:38no, that it's exactly my I want to have peg, so I would
- 51:45not I would not do it. And what you said something before that is
- 51:49important to just emphasize stem cells are your repair system, whether you feel something
- 51:54or not. When you put more stem cells in circulation, that's what stem
- 51:59cells do, they will either go and find an area in the body to
- 52:02go and repair, or they will be called back by the bone marrow.
- 52:07And as they go back in the bone marrow, if they come let's say
- 52:09from embryonic stem cells or from your fat tissue, as younger stem cells,
- 52:14they go back and they become another source of new stem cells that will be
- 52:20re released. So you're kind of repopulating your stem cells. Because that's how
- 52:23if somebody has a treatment for leukemia, what they do is that they irradiate
- 52:29the person and then inject stem cells in the bloodstream. These stem cells go
- 52:32back to the bone marrow and they reconstitute the entire bone marrow. So these
- 52:37stem cells when we inject them, they find their way to the bone marrow.
- 52:39So as you do this, you recreate a new younger strain if you
- 52:45want, of stem cells, and they will re echo for benefits for a
- 52:49long time after the injections. So my point in all of this is that
- 52:52as you put more stem cells in the body, they do what stem cells
- 52:57do. They will repair. You may not nessis Saley experienced the benefit and
- 53:00the thought that it was worthless because I didn't feel the benefit is a wrong
- 53:05conclusion. If your stem cells did not do what stem cells do, you
- 53:08would not be alive. Keep in mind, you have a liver and you
- 53:12liver every two three years. So the fact that you're still alive today means
- 53:15your stem cells are doing their work. So feeling them is great, I
- 53:20understand, but they do the job no matter what. That's really important.
- 53:24Okay, Well, you know, I wanted to tell you that I use
- 53:29a time would go buy very very fast today and it has and so they
- 53:32just flagged me that where you have to end it. But I wanted to
- 53:37let people know how to reach you and how to buy stem Regen, and
- 53:40I wanted to mention there that very generous offer that for the consumer who looks
- 53:50at your website, I guess goes to your website, which is what it
- 53:52is. It www dot stem Regen dot com. It's stem Regen dot co.
- 53:58So stem Regen dot C. Okay coo everybody, Okay, So go
- 54:02to the website and then we'll I'll work with Christians people to get a code.
- 54:09But the code that we usually use is ageless. So if I can
- 54:14just assume that will work, and if not, I will put it on
- 54:17the show. Notes, but if ages will work, that will get you
- 54:21a fifteen percent discount. And I've been using this product now for I think
- 54:27for four or five months, Christian, you so kindly sent me some and
- 54:31I take two a day. I don't you know, like you said,
- 54:36I'm not feeling any differently, but I know that they're doing their job,
- 54:39so that gives me comfort. So that's what I think everybody should be aware
- 54:44of. I can't think of a better way to increase your stem cells and
- 54:50to do it orally because the other available, the other injectable, is just
- 54:53not as practical for most people. So this is a way to address the
- 54:59issue that you stem cells are decreasing as we age, and they're not as
- 55:02a high quality. But this way, with the stem regen, you're giving
- 55:07your body its ability to produce its own And you know, I say this
- 55:10all the time to my my hormonal my endocrinologist doctor. I say, you
- 55:15know, I don't want my body to get lazy and stop making the thyroid
- 55:21or the DHA or whatever the hormone. So the same thing with stem cells.
- 55:25You want your body to be encouraged with the stimulants that are are the
- 55:31ingredients I don't want to say stimulate ingredients that are in the products here that
- 55:36Christian has so you know, just d diligently researched. I mean, you
- 55:42don't find products like this just anywhere. I believe me, I've done my
- 55:45homework on stem Regen. So I'm giving my you know, angels and timeless
- 55:52endorsement because I think you know that it's something very important that people should know
- 55:58about and easy to do. So okay, So to reach you if they
- 56:04have if someone had questions, Christian, is there somewhat a clinical person at
- 56:07your company that someone could talk to, Well, they can go on the
- 56:13well Instagram at stem Cell Christian and they can DM me there or if not
- 56:17care at stem region dot co and then it will get to somebody that can
- 56:22answer. Okay, because I'm sure a lot of people do have questions before
- 56:25they jump into something like this, or even after they've been taking it for
- 56:30a while. So all right, Well we have to, sadly, and
- 56:32but I spend a fascinating discussion and you've covered things that are complicated in a
- 56:38very lay person's way that you know, very understandable, and I know you
- 56:44probably have to come down several notches because this is you know, a visit,
- 56:49the talent unto itself to be able to take the complex and make it
- 56:52understandable for the for the masses. So I do appreciate that you can do
- 56:57that so effectively, and I would like to thank you for taking the time
- 57:01today and being so gracious to share your knowledge and this incredible product and your
- 57:08book. By the way, people want to read the book. Thank you
- 57:10again, Christian, have a beautiful weekend and take care of them. Okay, bye bye