Melatonin, Circadian Rhythms, and Nocturnal IOP Dynamics

Glaucoma, Vision & Longevity: Supplements & Science · Dec 12, 2025 · 14m

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Excerpt:

Melatonin and the Eye: Nighttime IOP and NeuroprotectionMelatonin is a neurohormone produced in a ~24-hour cycle (circadian rhythm) that plays key roles in sleep regulation and acts as a powerful antioxidant. In the eye, melatonin is synthesized locally (in the retina and ciliary body) and binds to MT1/MT2 melatonin receptors on ocular cells (). Its levels peak at…