Latest / Gladden Longevity Podcast
How Bitter Taste Receptors in Your Gut Can Instantly Kill Food Cravings - Episode 339
In this episode, Dr. Gladden and nutrition expert Sarah Kennedy discuss Calocurb, a natural extract that uses evolutionary biology to suppress appetite. The discovery focuses on bitter taste receptors (T2Rs) located throughout the gastrointestinal tract, which historically served as a protective mechanism to slow the consumption of potentially toxic substances. By using a specific New Zealand hop extract, Calocurb triggers these receptors to signal the brain that the body is full. This process stimulates the natural release of satiety hormones—GLP-1, CCK, and PYY—effectively quieting "hunger…
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