Latest / Intellectual Medicine / His PSA Was 16. But That Wasn’t the Number That Worried Me
Transcript
- 0:00In the world of prostate cancer treatment, how do we define
- 0:04success? What is considered an effective
- 0:08treatment? What is considered a good
- 0:10outcome? The only way you can be
- 0:12reassured that the treatment is working is when you actually die
- 0:16from something else. Well, that's a weird way to
- 0:19define success, isn't it? Here's a big question.
- 0:29In the world of prostate cancer treatment, how do we define
- 0:33success? What is considered an effective
- 0:37treatment? What is considered a good
- 0:39outcome? Well, I'm going to share with
- 0:41you how we define it within my protocol, compare and contrast
- 0:46it to the institutional medicine approach.
- 0:50Certainly one metric is death. We don't want to die from
- 0:54prostate cancer. The problem with using that as a
- 0:57criteria is the lag time. It can take 10 or 15 years to
- 1:03determine if the treatment you're doing now is going to
- 1:06prevent you from dying of prostate cancer.
- 1:09In fact, the only way you can be reassured that the treatment is
- 1:12working is when you actually die from something else.
- 1:17Well, that's a weird way to define success, isn't it?
- 1:20I mean, I don't want my patients to die at a premature age.
- 1:24So in my protocol, in our approach, I challenge the
- 1:28conventional definitions. In the absence of death, they
- 1:34have to look at disease progression.
- 1:36And this is where it gets a little bit hypothetical.
- 1:40They define disease progression as your PSA going up.
- 1:46In some cases, that becomes the only criteria that they're
- 1:49judging treatments based upon. I'm going to share with you a
- 1:54case of a patient who came to see me.
- 1:57He didn't want to get a biopsy. Listen to my podcast, read my
- 2:00book. Good for him.
- 2:03And he decided he wants to consider an alternative.
- 2:05Why do they want to biopsy my patient?
- 2:09He's in his mid 60s. He feels great.
- 2:12This is perhaps the most common presentation of men with
- 2:16prostate cancer. They feel great.
- 2:19But his PSA was over 16. Stop the presses.
- 2:25We must do a biopsy. But first, he cautioned, I want
- 2:29an MRIMRI is done. Here's a pyrides of five.
- 2:34Now, remember, the pyrides score is a judgement about whether or
- 2:40not the images look like cancer, and they're rated anywhere from
- 2:441:00 to 5:00. One means this is not cancer.
- 2:47A5 means yeah, this looks like cancer.
- 2:51A4 means it's probably cancer. A three is a coin flip.
- 2:55So you get the picture here, PSA above 16 pyrides of five and a
- 3:02male greater than 60. That spells prostate cancer
- 3:06gang. So why do a biopsy?
- 3:09Why do a biopsy when you're not going to believe it if it's
- 3:13negative, right? This is the lack of intellectual
- 3:17reflection. This is reflexive, dogmatic
- 3:21institutional medicine. You know me say biopsy.
- 3:25Why? Because it's what we do.
- 3:28We biopsy. Yeah, but but the dude's got
- 3:32prostate cancer. By every reasonable criteria, it
- 3:36is so evident that if you biopsy him and if the biopsy comes back
- 3:41negative, you're not going to believe it.
- 3:44The biopsy, folks, it's not benign.
- 3:47People land in the hospital with sepsis.
- 3:50It can damage erectile function. It can damage urinary flow, so
- 3:54it's not a trivial procedure. Don't let them fool you.
- 3:57Should not be done ever. But fortunately my guy dodged
- 4:00that bullet. Came to see me, now we're
- 4:03talking about what to do next. To a reasonable degree of
- 4:08medical certainty, the cancer exists.
- 4:11What treatment is then available with APSA above 16?
- 4:15Take out the gland radiation castration.
- 4:20How about none of the above? His MRI demonstrated that the
- 4:24cancer looked as if it had gone outside the capsule.
- 4:28Now the capsule. Think of it like the rind of an
- 4:31orange containing the material within it, including the cancer.
- 4:36If your cancer is within that capsule, it's not going to kill
- 4:40you. If it goes outside, the capsule
- 4:42encroaches upon it. Now it can become more
- 4:45problematic. It is still eminently treatable.
- 4:49It is not a cause for doing destructive therapies with some
- 4:54false hope that it's going to avoid death, right?
- 4:57That's not going to happen. So my guy's seeing me.
- 5:01He has what I call level 2 prostate cancer already
- 5:04extending outside the capsule. No biopsy, no surgery, no
- 5:09castration, no radiation. We put him in the protocol.
- 5:14What's the goal? The goal is to have it, not
- 5:17progress. The goal is not to cure cancer
- 5:22and have all the all the nodules disappear.
- 5:25Yes, that has happened with men. In my protocol it can't occur.
- 5:30But that is not the gold standard for for treatment
- 5:34success. As long as this cancer doesn't
- 5:37progress, my guy is going to take it to his grave, feeling
- 5:41great, dying of something else. So what happened after a cycle
- 5:46of treatment, his PSA went from 16 to 16, didn't go up.
- 5:53It had been trending up 10121416 stop the trend.
- 5:59That's one success. The other success, no anatomical
- 6:04progression. So we repeat the MRI.
- 6:06This is why I like to do it without contrast.
- 6:09Guys, that gateolinium accumulation in your brain,
- 6:12that's not good. I don't care what they try to
- 6:14tell you, it doesn't belong there.
- 6:17So we avoid the contrast. We don't need it.
- 6:20Those who think it's essential are simply not knowledgeable
- 6:25about the latest trends and evidence.
- 6:27Right, so no contrast then We can use it sequentially.
- 6:30It's fast, about a 15 minute study.
- 6:33It's pretty cheap, about 400 bucks in the world of medicine.
- 6:37Not a Backbreaker. Usually insurance covered when
- 6:41you compare one MRI to the next MRI.
- 6:44Yes you gauge each individual study with a bi rad score, but
- 6:49you compare 1 to the other with a precise score.
- 6:53That's all capitals. It's an acronym and it's a means
- 6:57of judging. Has it gotten worse, better, or
- 7:00stayed the same? A precise score is rated one to
- 7:04five. One means wow this really
- 7:07improved. 5 means Yikes it's getting a lot worse.
- 7:11A3 means no change. Success is defined in my
- 7:16protocol by a stable PSA. Even if it's inching up, it's
- 7:21stable and by a precise score of three or less.
- 7:26On occasion A precise score of four can be acceptable depending
- 7:30on detail, but you get the picture.
- 7:32No progression, no harm being done.
- 7:36Urinary flow is good, erections are great, energy is great.
- 7:41The protocol includes a focus on global health, not just the
- 7:46prostate. We got to remember there's a man
- 7:50attached to that prostate gland and his global health is
- 7:53relevant and his vitality is critical.
- 7:57The idea that we should do damage to a man who feels well
- 8:02with this false hope of preventing death is foolishness.
- 8:07Now back up the camera a little bit, right?
- 8:10What in men with prostate cancer die from answer heart attacks.
- 8:16Number one killer of men with prostate cancer.
- 8:19I believe it is in part because many of the treatments are
- 8:22damaging to the heart, right? The heart's a muscle gang.
- 8:26You whack testosterone, it's losing some of its merit.
- 8:31The radiation therapy damaging to the heart, hormone blocking
- 8:36therapy damaging to the heart. If you die of a heart attack,
- 8:41some of the people that are advocating this type of
- 8:43treatment for prostate cancer consider it a relative success.
- 8:48I mean, you didn't die of prostate cancer.
- 8:50That's nonsense as well. Premature death from any cause
- 8:55is to be analyzed and avoided. What is premature death?
- 9:00Anybody that dies before the age of 90, I consider premature.
- 9:03My goal for my patients is to get to 100.
- 9:06Now. The goal's important, folks.
- 9:08You're all familiar with the concept of a predetermined
- 9:12outcomes. Expectations become reality,
- 9:16right? And if I presume my patients are
- 9:19going to be happy making it to 80, I may be a little bit
- 9:22passive as they get into the mid late 70s Nonsense.
- 9:26We need to be proactive. So what do we do for our guy?
- 9:30Well, I know the number one killer is heart.
- 9:32Heart attacks and cholesterol has some merit, but the great
- 9:37test is the calcium score. A calcium score is a CAT scan of
- 9:42the heart and it can determine if there's hardening of the
- 9:46arteries. It can see calcium build up on
- 9:48the artery. So now we don't want to die from
- 9:50prostate cancer. Job well done.
- 9:53Things are stable. Precisely 3.
- 9:55The PSA is stable. He's happy.
- 9:57Life is grand. What about the heart?
- 10:01The calcium score, if it's zero, that's like a 10 year free pass.
- 10:06Likelihood of death from heart attack is really hardly present
- 10:10at all. That's fantastic.
- 10:12By the way, this is for men over 50.
- 10:15If the calcium scores above 100, that indicates a significant
- 10:19amount of calcium buildup on the coronary arteries, considered an
- 10:24increased risk of cardiac events.
- 10:27Well, what was my guy's calcium score?
- 10:29It was over 900. Now that doesn't mean he's going
- 10:33to drop dead tomorrow. It does not mean you need to go
- 10:35to the emergency room. But it does mean we uncovered a
- 10:39critical risk that would have been missed if they were so
- 10:43ambitious to jab needles in his prostate.
- 10:47On top of that, the hazard is amplified because of the
- 10:51pre-existing cardiac risk. Look at the big picture.
- 10:55Don't let them fool you into thinking that they have a cure.
- 10:59They don't we know that prostatectomy is removing the
- 11:02gland, that amputation doesn't prevent death from prostate
- 11:07cancer, nor does radiation, nor does hormone blocking therapy.
- 11:12So protocol approach. Check out the heart.
- 11:15Now we can do things to focus on his global vitality and
- 11:19well-being, maintaining strength, maintaining energy,
- 11:23maintaining vitality. If you chase the number, well,
- 11:28your PSA is above 16, Mr. Smith, we got to get it down.
- 11:31Getting your PSA down doesn't make you feel better, doesn't
- 11:34heal you, does not necessarily correlate with the status of the
- 11:38cancer itself. I've had men in my practice with
- 11:42PSA's that didn't budget. They're like 567.
- 11:46But the MRI evaporated the nodules.
- 11:50So you got to analyze the proper detail and you have to make the
- 11:56right judgement about how to define success.
- 12:00In a conventional world, they would have done something to
- 12:03this guy now at a point in time where he feels great.
- 12:08You know, I had a patient once, his PSA was in his 60s, known
- 12:13prostate cancer, and he was told by his other docs, you must go
- 12:18on home. And blocking this PSA is way too
- 12:21high. Calls me up in a panic.
- 12:23What am I going to do? I said nothing.
- 12:25How do you feel? I feel great.
- 12:27Goes to work everyday. Makes love to his wife.
- 12:30Your inflow is good. What are we doing, folks?
- 12:33We're treating a number. We're treating a number.
- 12:37They like treating numbers. Those are Thunder for a dramatic
- 12:40effect. In medicine, we like treating
- 12:42numbers. Right.
- 12:43It's concrete. Yeah.
- 12:45Your PSA used to be 16. Now it's four.
- 12:48Aren't I great? Aren't you happy?
- 12:50I know you feel kind of lousy from the treatment I'm giving
- 12:53you, but boy, it's preventing you from dying.
- 12:56It is not so, my guy, at 60, we wait.
- 13:00His PSA went up to 90. He felt great.
- 13:03We wait. PSA went up to 160.
- 13:07At this point, five years later, started to have some urinary
- 13:12flow issues. Then you take the action.
- 13:15Then you can do hormone mitigation.
- 13:18You never, ever, ever get castrated.
- 13:22That's no way to live. No way to live, guys.
- 13:24They try to tell you it's essential to save your life.
- 13:27It is not guaranteed harm, no tangible benefit.
- 13:32Why are we stuck in this? I'll tell you why.
- 13:35It's because the voices have been stifled.
- 13:40My voice is out there. Not many.
- 13:42I actively treat patients. Most don't.
- 13:45I'm a board certified osteopathic family doctor.
- 13:48What am I doing in this space? I'm being bringing a fresh
- 13:51perspective. Got to look at it differently.
- 13:55If we want a different outcome. The institutional docs, they got
- 13:59that monolithic path they've developed over decades and it's
- 14:03great because you just follow the bread crumbs.
- 14:07You high PSA, I'm going to do this, I'm going to do this and
- 14:08biopsy. I'm going to do this to what
- 14:12benefit, right? There's enormous financial
- 14:16incentive in maintaining the status quo.
- 14:18Enormous. These focal therapies are coming
- 14:21out with all of them brag about their success rate nonsense.
- 14:25They're not going to work. Why do I know that without
- 14:29waiting 15 years? If you take the entire gland out
- 14:35and it doesn't affect the death rate from prostate cancer, what
- 14:39logic supports the thought that taking a portion of the gland
- 14:43out is then going to work? There's no logic.
- 14:48It's just a false hope with enormous financial backing,
- 14:53right? Stuff that is inexpensive, stuff
- 14:57that is generic, stuff that supports your health does not
- 15:02make the cash registers ring at your friendly neighborhood
- 15:05hospital medical treatment center.
- 15:08I mean, we all know that in America we pay caviar prices and
- 15:13we get oatmeal results, right? Our cost is nuts.
- 15:18Look, I don't mind folks spending money, but I want some
- 15:22value here, right? So it indicts the current
- 15:26treatment pathway. Let me rephrase.
- 15:29It invites reasonable consideration of alternative
- 15:33approaches so that men so that you have a choice.
- 15:38You don't have a choice if you're going to follow the
- 15:43frozen footsteps of institutional medicine.
- 15:47You don't have as much choice if you're going to allow yourself
- 15:50to be handcuffed by what the insurance says is right for you.
- 15:55This is not breaking the bank's stuff, folks.
- 15:59Where do we ever start to defer our judgement about our own
- 16:04health to an insurance company? Well, you know, I, I, I, I, I
- 16:08would do another treatment, but my insurance won't pay for it.
- 16:12That's dumb. Insurance doesn't pay for your
- 16:15health. They don't pay for your
- 16:18well-being. They don't pay for vitality.
- 16:20This is a new age, folks. Vitality can be restored,
- 16:24maintained unto your death, not through conventional treatment.
- 16:29So think about how you want to live.
- 16:31I'll continue to share this information with you.
- 16:34This is cutting edge. This is a potential to alter the
- 16:38way that prostate cancer, especially those early stages,
- 16:41are managed. Robbing a man of his vitality
- 16:45with false hope is no longer necessary.
- 16:48Probably never was. The growing evidence makes
- 16:52current treatments less tenable. It gets harder and harder for
- 16:56them, The conventional institutional docs, to impose
- 17:00these treatments upon a public that is getting more and more
- 17:04knowledgeable. Thank goodness for the Internet,
- 17:08for AI, for your ability to search and validate what I'm
- 17:12saying with your own supportive data.
- 17:16Well, listen, I, I hope you stay with me.
- 17:18This is important. We're going to be grassroots
- 17:19changing medicine. It's not happening from the top
- 17:22down. It's happening from us demanding
- 17:25better. So comment, leave messages.
- 17:28We love to hear from you, ask questions, suggest topics.
- 17:32This is your formal forum as much as mine.
- 17:36Well, thanks for being part of this podcast.
- 17:37I look forward to connecting online in the future.
- 17:41Keep watching. Bye.