Latest / Intellectual Medicine / The Surprising Truth About Prostate Cancer and Mortality
Transcript
- 0:00What do we do with a gentleman who has prostate cancer?
- 0:05Evaluate their heart. That's the thing that'll deprive
- 0:08you of your abundant life. Sudden death.
- 0:10Most common symptom of coronary artery disease is sudden death.
- 0:16That's hard to treat. I don't have any remedy for
- 0:20sudden death, so we have to look ahead.
- 0:22Your insurance company doesn't pay for it.
- 0:24Would you stop already with the insurance companies?
- 0:27They are not the arbiters of your health.
- 0:29They're there to collect the premium.
- 0:32Your job is to stay healthy. Time to join the revolution.
- 0:38All right, so you have a high PSA.
- 0:40Maybe you have cancer, prostate cancer.
- 0:43I guess that's why you're listening to the podcast or you
- 0:46know somebody who has it. The question then becomes, are
- 0:49you going to die? Are you going to die from
- 0:51prostate cancer? What's the thing that kills most
- 0:55men with prostate cancer? I'm about to tell you it's a
- 0:58little bit surprising. I get it.
- 1:00Nobody wants to die. Well, most of us don't.
- 1:03You know me. I don't know.
- 1:05I I don't want to die, like, now.
- 1:07But the idea of never dying is creepy.
- 1:10So we all have an existential sense that the end of life will
- 1:15come, and now we ignore that so we can enjoy living.
- 1:18We like to just forget the fact that one day either you or me
- 1:24ain't going to be here. Now there's the existential
- 1:28sense of it. And then, gentlemen, you who've
- 1:30been diagnosed with prostate cancer, you who are harboring
- 1:33that elevated PSA, you who had that abnormal MRI, or if you
- 1:39haven't heeded my advice and went forward with a biopsy, you
- 1:42who have the Gleason score will tell you why that's irrelevant
- 1:45in a moment. Have a clear and present sense
- 1:48of your own mortality. OK?
- 1:50Embrace that for a moment. It's not a horrible thing.
- 1:54It focuses the senses. Now, I'm not advocating that we
- 1:58passively allow ourselves to die from prostate cancer.
- 2:02I'm advocating that we're all going to die.
- 2:05We don't want to die from prostate cancer.
- 2:08And most importantly, at least in my experience, people don't
- 2:12want to suffer. They don't want to grind limp
- 2:16and wither. Many of you have had the painful
- 2:20experience of walking the path toward death of somebody who's
- 2:24dying slowly. It's God awful.
- 2:27So what I want for you all is abundant life.
- 2:30And one way we get there is by not allowing ourselves to be
- 2:34exposed to things that compromise our vitality with the
- 2:39fallacious belief that'll make us live longer.
- 2:42Chief among those things are conventional treatments for
- 2:47prostate cancer across the board.
- 2:49Across the board, Prostatectomy, radiation seeds.
- 2:53What about no, just stop now? How do I say that?
- 2:57I'm not just making this up out of the top of my head?
- 2:59The studies are in, folks. The studies are in.
- 3:03They're not widely publicized because they threaten a multi
- 3:08billion dollar industry. There are two major studies that
- 3:13I glean most of this information from, but let's go to the heart
- 3:17of the matter, right? You have prostate cancer.
- 3:19What are you most likely to die from?
- 3:22According to the Protect T trial, a study published in the
- 3:26New England Journal of Medicine in 2023 evaluated men with
- 3:30prostate cancer over 15 years on average, and they found that the
- 3:36most common cause of death was yes, it was cancer, but no, it
- 3:40was not prostate cancer. It's other forms of malignancy.
- 3:44How about that? You have prostate cancer, You're
- 3:48most likely to die from some other kind of cancer.
- 3:51So what's going on? It's possible the treatment
- 3:54itself is so weakening to your immune system, so devastating to
- 4:00your cellular health, that it sets you up for cancer.
- 4:05Radiation therapy increases leukemia, lymphoma risk.
- 4:08Chemotherapy runs the risk of cancer by virtue of weakening
- 4:12the immune system. Testosterone ablation,
- 4:16testosterone is part of your immune system support.
- 4:20So all these things are relevant.
- 4:22Another common cause of death #2 actually in the protectee trial,
- 4:27again, not prostate cancer, it was heart disease, lung
- 4:33infection. But then stroke, right?
- 4:35I can think of few more horrible ways to exit than having had a
- 4:39disabling stroke first. But those were the risk folks.
- 4:43So you have prostate cancer. Do not over focus on your
- 4:48prostate. You got to take a broadview.
- 4:51So what is a a humble family doctor like me doing in the
- 4:53prostate cancer world? I'll tell you because I can look
- 4:57at it from the outside in, take a step back and realize what are
- 5:01we doing? There needs to be a revolution
- 5:05in care. We need to pull away from the
- 5:09gravitational pull of Oh my God, you have prostate cancer, we got
- 5:13to get you in right away and take out before it.
- 5:16But no, just no. OK, so if you're not going to
- 5:20die from prostate cancer even though you have prostate cancer,
- 5:24then what should you consider doing?
- 5:27Had a gentleman and recently he had a Gleason score of 6.
- 5:31That's right. He got a biopsy before he had a
- 5:33chest talk to me. Never do a biopsy.
- 5:36I don't think you should ever do a biopsy.
- 5:38All right, we'll continue to dive into why.
- 5:41Gleason score of 6. And what do we do with a
- 5:44gentleman who has prostate cancer?
- 5:49Evaluate their heart. That's the thing that'll deprive
- 5:52you of your abundant life. Sudden death.
- 5:54The most common symptom of coronary artery disease is
- 5:59sudden death. That's hard to treat.
- 6:02I don't have any remedy for sudden death, so we have to look
- 6:06ahead. If you're over 50, just get a
- 6:08calcium score. Why?
- 6:10It'll show you whether or not you have hardening of the
- 6:11arteries, whether or not you're at risk for future heart
- 6:14disease. It's a powerful prognostic tool.
- 6:18Your insurance company doesn't pay for it.
- 6:20Would you stop already With the insurance companies, they are
- 6:23not the arbiters of your health. They're there to collect the
- 6:27premium. Your job is to stay healthy.
- 6:30Your job is to pay a premium and get ripped off because he didn't
- 6:34use it again this year. Right?
- 6:35How about that for a concept? Pay my premium.
- 6:38Another year went by and I didn't need, you know, to have
- 6:40bypass surgery. Doesn't that suck?
- 6:42No, it's great. Anyhow, the prostate, the
- 6:46calcium score is an out of pocket expense.
- 6:49In our neighborhood. It's about 100 bucks, maybe 150.
- 6:53Chump change. I pay more to fill up my car
- 6:55with gas. Not really, but yeah, I know a
- 6:59little bit less. Anyhow, you get the point.
- 7:01So heart disease is relevant. Be careful.
- 7:05Be careful of treatments. So what about the trial?
- 7:09One study published in 2017 called the Pivot trial.
- 7:14They looked at men with prostate cancer across the board.
- 7:19Half of the men got their prostate gland removed.
- 7:23The other half did nothing. Now pause and freeze frame for a
- 7:27moment the concept of either ripping out your prostate gland
- 7:30or patting you on the back and saying good luck.
- 7:33I hope prostate doesn't kill you.
- 7:36Well doc, what do you got from me?
- 7:38We got nothing. That's not true.
- 7:40It is not true. Your body is fighting cancer
- 7:44every single day. You need to help it.
- 7:48You need to do things that support the fight.
- 7:50Now, I empathize with you guys because you're stuck.
- 7:54You have the urology community, the oncology community.
- 7:56Ask them what you can do. They have no knowledge of
- 7:59nutrition. They have no knowledge of
- 8:00supplements. They have no knowledge about
- 8:02what can be done. Repurposed drugs applied to help
- 8:06kill and prevent cancer. Rational, safe, plausible.
- 8:12So in the future, what I hope to see happen is let's compare the
- 8:19conventional approach to the Pederuti protocol over the
- 8:22years. You know, is it possible that
- 8:25we're actually instigating metastatic disease and
- 8:29accelerating the rate of cancer death by virtue of jabbing
- 8:33needles into the prostate gland? There is no known answer to
- 8:38that. They anybody, any Doctor Who
- 8:41tells you that, oh, don't worry about the biopsy.
- 8:44That's not been shown to spread cancer, all right?
- 8:48It's never been studied. It hasn't been shown because
- 8:51nobody looked. Now, it's going to take years,
- 8:55but those of you that are choosing the Pedruti protocol
- 8:59without a biopsy, we're going to get a cohort of data that will
- 9:03be illuminating to me. It is intuitively logical.
- 9:08If you stick a needle in cancer and you make a bloody mess of
- 9:11it, it's more likely to spread. The problem is we have no, no,
- 9:17no delta, no comparison group because literally everybody gets
- 9:21jabbed because that's the standard of care established in
- 9:261980. And we haven't moved the needle.
- 9:30Killing me, folks. You're killing me smalls.
- 9:32All right, let's go back though, to the stats here because
- 9:35they're revealing the pivot trial. 20 years, men, prostate
- 9:40gland removed. Men did nothing. 20 years later,
- 9:44no difference in death from prostate cancer.
- 9:50What? But I had my prostate gland
- 9:53removed. Doctor, how could I have
- 9:55metastatic disease? Well, I don't know some of the
- 9:57cells, but no difference in death from prostate cancer
- 10:04whether you get the gland removed or not.
- 10:07And here's an interesting detail when comparing the stage of the
- 10:13cancer, the Gleason score, the magnitude of it, no difference
- 10:19in death whether or not you remove the gland.
- 10:21So this notion that you have to get a prostate biopsy, we have
- 10:25to know the Gleason score so it can help us decide what to do,
- 10:30is rendered moot when you realize that the outcome is the
- 10:34same with or without the prostate being removed.
- 10:38So what is a man to do? You protect your health.
- 10:44You do not let them strip you of your manhood without a colossal
- 10:48upside. There's no upside.
- 10:49Guys, keep your prostate gland and by all means, never ever let
- 10:56them irradiate you. And here's the stats on that.
- 11:00So the pivot trial did not look at radiation.
- 11:02They just looked at yes, no surgical removal, 2017, 2023,
- 11:08the Protect T trial looked at that element, surgery, radiation
- 11:14or nothing. Once again, no difference in
- 11:18prostate cancer death among all three groups.
- 11:22No difference. What are we doing?
- 11:26You're going to die, folks, right?
- 11:29Be prepared. Be prepared.
- 11:31This is a little bit of a reflective thing, right?
- 11:33I've, I've sometimes wondered, would I rather have a sudden
- 11:36death episode or would I rather like, yeah, I get some kind of
- 11:38like forewarning. It's like, you know, so I could
- 11:41do like, I don't know, a novena or something, you know, before I
- 11:44die. So I get into heaven.
- 11:46I don't know, maybe I should be prepared regardless.
- 11:49Maybe that's a good idea for all of us.
- 11:51Anyhow, let's go back to protect T, right?
- 11:53Those 3 branches. It is true that there was a
- 11:57slight increase in metastatic disease and the people who did
- 12:01not do anything. But here's a fascinating detail.
- 12:04I think it's fascinating of the men who ended up with metastatic
- 12:09disease in the groups, right? The group that did nothing and
- 12:14the group that had surgery and the group that had radiation
- 12:19after 10 years when they acquired metastatic disease, the
- 12:23death rate in those three cohorts was 13% for the folks
- 12:30who did nothing and then subsequently developed
- 12:33metastatic disease. So you do nothing, 10 years
- 12:36later you get metastatic disease in your bone, 15 years later, 13
- 12:40percent death rate. OK.
- 12:42If you have the surgery to remove the prostate gland, 10
- 12:45years later when Mets occurred or if they occur, the subsequent
- 12:51death rate at 15 years is about 25%.
- 12:55So if you get metastatic disease and you've had your prostate
- 12:58removed, based upon the study, there may be an increased rate
- 13:02of death. Hard to explain why.
- 13:05The radiation group after 10 years, if they get metastatic
- 13:09disease, by 15 years their death rate was 70%.
- 13:15Wow, think about that. Now, I know this sounds
- 13:19uncomfortable, guys, but the best approach?
- 13:22Avoid surgery. Avoid radiation, apply
- 13:26alternative treatment. Of course, I advocate the
- 13:28protocol I've developed. Not proven to cure cancer, not
- 13:31proven to prevent its progression, but built on
- 13:34evidence of potential benefit regarding the repurposed drugs.
- 13:40An unequivocal benefit regarding lifestyle modifications, right?
- 13:44Chief among them, lower percent body fat.
- 13:47It's better than to wait to develop metastatic lesions and
- 13:52then treat them than it is to do so in a pre emptive manner.
- 13:58That is, there's no good evidence that starting radiation
- 14:02or androgen deprivation or any kind of a treatment just because
- 14:06your PSA is going up. There's no good evidence it's
- 14:08going to help you live longer. It will make you feel bad.
- 14:11It will make you miserable in all likelihood.
- 14:14So we have to really carve through the noise and it's
- 14:17really hard. It's hard to get a full amount
- 14:20of information. The time it takes, like in the
- 14:24few minutes we've spent, that's probably as much time as we get
- 14:27with your urologist. It's hard for them to explain
- 14:30all this. Number one, they're obliged
- 14:32almost to do standard of care. How will the standard of care
- 14:35ever change if we're all doing the same thing over and over and
- 14:38over again? And these studies have been in
- 14:41the literature and they're having some effect, but it's too
- 14:46slow. Too many men are being hurt,
- 14:48they're being overtreated. They're being scared to take
- 14:52steps that are not in their best interest.
- 14:55So as you contemplate your fake guys, think about staying vital,
- 14:59staying healthy, living life in the moment.
- 15:02And don't let anybody put a timeline on your lifespan.
- 15:06Hey, if you have metastatic lesions, as you listen to this
- 15:10properly manage, you got years in most cases.
- 15:14All right, well, here's to abundant living.
- 15:16Have a great time out there folks, and stress not because
- 15:20stress is bad for your immune system.
- 15:21All right, team, I'll see you all next time.