Urine and Plasma Extracellular Vesicle Analysis for Monitoring Renal Recovery after Acute Kidney Injury
AKI can lead to incomplete or maladaptive repair and progression toward CKD, yet current clinical markers provide limited information on the biological processes underlying recovery. Tanzi and colleagues explored extracellular vesicles (EVs) from urine and plasma as a minimally invasive liquid biopsy to monitor these processes. EV surface profiling captured complementary signals associated with local kidney repair and systemic responses and distinguished different trajectories of renal recovery. Integrating urinary and circulating EV information may therefore provide a more comprehensive view…
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