Pharma 55: Helminth Infections - Targeting Giants with Subtlety

Clinical Deep Dives · Feb 3, 2026 · 1m

This is a free preview of a paid episode. To hear more, visit drmanaankarray.substack.com

This episode examines antihelminthic therapy as the pharmacology of selective vulnerability. Helminths are biologically sophisticated, multicellular organisms-far closer to us than bacteria-yet they harbour unique neuromuscular and metabolic features that drugs can exploit. We explore mechanisms that paralyse, starve, or dislodge worms, and why cure oft…