Latest / Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Quinapril Pharmacology
On this podcast episode, I discuss quinapril pharmacology, adverse effects, drug interactions, pharmacokinetics, and much more.
Quinapril is a prodrug that is converted in the liver to its active metabolite, quinaprilat, which inhibits ACE, leading to decreased formation of angiotensin II and reduced aldosterone secretion.
Hyperkalemia can occur with quinapril use due to decreased aldosterone, leading to potassium retention—especially in patients with renal impairment.
Concomitant use of potassium-sparing diuretics or potassium supplements with quinapril increases the risk of hyperkalemia…
The skinny
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