Myelofibrosis | Oncology Today with Dr Neil Love: Current Management of Myelofibrosis

Research To Practice | Oncology Videos · Nov 3, 2022 · 58m

Featuring an interview with Dr Brady Stein, including the following topics:

Case: A man in his late 70s with myelofibrosis (MF) presenting with fatigue and night sweats (0:00)

Incidence and severity of fatigue and other symptoms; use of symptom scales to measure severity (3:43)

Rapidity of symptom response to ruxolitinib; emerging data with momelotinib (7:34)

Novel therapeutic targets for MF: BET, PI3K and BCL2 (13:25)

Available data on JAK inhibitors for essential thrombocytosis and polycythemia vera; pathogenesis of pruritus and optimal management (20:31)

Clinical pearls on managing…