Micro 23: Neisseria and Related Genera
This episode introduces the Gram-negative diplococci of the genus Neisseria, organisms defined by their kidney-bean–shaped pairs and strict human host adaptation. Drawing from Murray’s Chapter 23, the focus centres on Neisseria gonorrhoeae and Neisseria meningitidis, two pathogens that share morphology yet diverge dramatically in clinical expression.
The narrative begins at the mucosal surface. N. gonorrhoeae adheres to urogenital epithelium using pili and outer membrane proteins, evades immune detection through antigenic variation, and triggers intense neutrophilic inflammation. The result…
The skinny
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