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931-Gyrencephalic Niche for Postnatal Interneuron Migration

Recent neuroscientific research identifies a specialized developmental structure called the Arc within the subventricular zone of mammals with folded brains, such as humans, primates, and pigs. This complex region facilitates the continued migration of inhibitory interneurons after birth, a process notably absent in species with smooth brains like mice. Using transcriptomic sequencing and advanced imaging, scientists discovered that these young neurons travel along distinct dorsal and ventral pathways to reach the frontal and temporal cortices. This prolonged migration significantly…

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