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Phase 3 Trial of Brepocitinib in Dermatomyositis
This source describes a phase 3 clinical trial evaluating the efficacy and safety of brepocitinib, an oral medication designed to treat adults with dermatomyositis. The study compared two different doses of the drug against a placebo over a one-year period, specifically focusing on patients whose condition had not responded well to previous therapies. Researchers found that the 30-mg dose significantly improved muscle strength, skin health, and overall physical function while allowing patients to reduce their reliance on steroids. Conversely, the 15-mg dose did not meet the necessary…
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