Latest / The Dr Louise Newson Podcast / 26 - How hormones and lifestyle shape healthy ageing
Transcript
- 0:00So for World Menopause Month in October, I'm going to be coming
- 0:03to three theatres, the 5th of October in Glasgow with Kay
- 0:07Adams, the 12th of October in Birmingham with Liz Earl and the
- 0:1119th of October in Kingston near London with Emma Barnett.
- 0:16I'm going to be doing AQ and A so these women will be
- 0:19questioning me, asking me about my background, my work and also
- 0:25about hormones. And the second-half will be
- 0:28audience asking questions. So there'll be lots of
- 0:30opportunity to put your questions across.
- 0:33You can ask me anything, of course.
- 0:35And I really look forward to meeting some of you there.
- 0:40So today my podcast guest is Doctor Tash Morando.
- 0:43She's auk trained GP, but she now works in Singapore.
- 0:47We talk a lot about preventing diseases.
- 0:50We talk about the foundation, so which is really lifestyle.
- 0:55We talk about aging, is it a disease or not, what we can do
- 1:00to be healthy as we age, and talking about health span versus
- 1:04lifespan. It's a really great conversation
- 1:07with lots of really good practical tips as well, so I
- 1:11hope you enjoy it. So Tash, it's great you're over
- 1:18here. Last time I saw you in fact, was
- 1:21over here in London, and before that I was over in Singapore.
- 1:25Like, it's just amazing because you're an NHSGP very, very, very
- 1:30part time over in the UK, aren't you?
- 1:32But you mainly work out Singapore.
- 1:35But you're really interested in me about keeping people healthy.
- 1:39I am. Thanks, Louise.
- 1:40Thanks. It's really nice to actually be
- 1:42here in person doing this because the first one we ran was
- 1:45was virtual. And I never met you?
- 1:46Then no. We hadn't.
- 1:47No, and now I feel like I'm really close to you.
- 1:50We what's up with each other a lot, but lots of people think
- 1:53it's really weird when I talk about wanting to prevent disease
- 1:57rather than treat disease. And I know you're the same as
- 2:00me, but I'm very reflective. And I think about when I trained
- 2:03as a doctor, I learned and we learned a lot about diseases and
- 2:08how to treat them. And obviously that's really
- 2:11important. But the older I've got, the more
- 2:14I'm trying to prevent disease in people.
- 2:17I say people rather than patients because they won't be
- 2:20patients if we reduce diseases. And it's so important, isn't it?
- 2:24Couldn't agree more to be honest.
- 2:26We really need to start moving away from the sick care model.
- 2:30I really don't want to be looking after sick people.
- 2:33I want to look after, well people and get them optimised
- 2:37and feeling better, yeah, Because that means I know for my
- 2:41own longevity that I can keep going a lot longer doing what I
- 2:47love doing, just getting people feeling well and optimised,
- 2:52which is great. It's so important.
- 2:54I mean, I'm very fortunate, like a lot of people know who my
- 2:57mother is because she's been on the podcast, but mentally she's
- 2:59really good and physically she's not bad.
- 3:02And I've always been really inspired just expecting other
- 3:05people to be like that when I was younger and watching her.
- 3:09But then as AGP, and I know you've done the same, you go to
- 3:12nursing homes, residential homes, care homes, sheltered
- 3:15homes, and it's usually women who are sitting there staring
- 3:19into space. And I've always been petrified
- 3:21thinking I don't want to turn into that woman.
- 3:23I want to be the woman like my mother.
- 3:25And there are so many ways that we could probably reduce that.
- 3:29Some of it is genetics. And we can't really change our
- 3:32chromosomes, but we can change our genetic makeup by what we do
- 3:36and how we eat and how we exercise, what we put into our
- 3:39bodies. We're not really thinking about
- 3:41it so much. Sometimes as doctors, we're not
- 3:44thinking about the end game, are we?
- 3:46And I think we have to be to save healthcare systems, not
- 3:49just in the UK, but Gloverly as well.
- 3:51Yeah. We have to think of it at a
- 3:53population level as well at this point in time.
- 3:56So I'm a lifestyle medicine physician as well.
- 3:59And for me that's a non negotiable right, because
- 4:02lifestyle is what we are in control of and the way we do
- 4:07things in a sustainable way means we keep going for as long
- 4:11as we keep going. So the term longevity, we're
- 4:13trying to move away from that because it seemed to be used in
- 4:17different ways and forms. So part of the healthy longevity
- 4:20medicine society. And I've just come back from
- 4:22Copenhagen, which was very lucky to be a part of the aging
- 4:27research and drugs development conference.
- 4:30And really what we're looking at is how do we make this just like
- 4:34lifestyle medicine is a specialized within medicine, how
- 4:38do we get Jairoscience, Jairo medicine?
- 4:41So the science of aging and how we do it well, but it's also
- 4:46about living that best quality of life.
- 4:49So it's not about lifespan, which is the age we live until
- 4:54it's about health span, which is the age we are healthy until.
- 4:57Yeah, right now that gap between the two is about 10 years.
- 5:00Especially for women, it's worse for women, isn't it?
- 5:03So I often say to people that it's not the age we die, it's
- 5:05the journey to that age. And that's completely what
- 5:08health span is about, isn't it? And I was reading a paper last
- 5:13night recently in the late 1970s about ageing, and it was a
- 5:19philosophical paper about is ageing a disease or not?
- 5:23And I can argue it both ways actually.
- 5:26I don't know what your thoughts are about ageing being a
- 5:28disease. And that's a tough one because
- 5:31as soon as you start labeling something that is inevitable.
- 5:35So ageing is inevitable. However, doesn't mean you have
- 5:39to get older, right? I'll take a solid 85 and be
- 5:45happy on a tennis court and be done right, but do you really
- 5:48want to be diseased and not be able to have that quality of
- 5:52life? So I think that's a tricky one.
- 5:54It's hard. It is really hard and that's
- 5:56something you know, probably need hours to debate over.
- 5:59That's his and the whole definition of disease in itself.
- 6:02And I often play mind games, you know, Is menopause a disease or
- 6:06not? Is being in labour and being
- 6:09pain in pain when you're in childbirth, is that a disease or
- 6:12not? And of course people will have
- 6:14different opinions, but I think with ageing, it's something like
- 6:17you say, we can't avoid, but we can reduce the negative impact
- 6:22on our bodies. And I think that's what's really
- 6:25important, isn't it? And that is, and again, this is
- 6:27where I'll go back to that lifestyle piece because I, you
- 6:31know, when I explain it to my patients, I say, think of it as
- 6:33a pyramid, that foundation, that's your lifestyle.
- 6:37You solidify that foundation with no cracks in it, which
- 6:41means in everything we do to optimize on top of that actually
- 6:45makes sense and it works. It's very hard to treat and
- 6:50supplement someone who hasn't really optimized that
- 6:55foundation. So prioritizing sleep,
- 6:59nutrition, especially protein and fibre, strength training.
- 7:03We had a little strength competition before coming here
- 7:07today. And then that in turn means your
- 7:11mental health should be so much better.
- 7:14You get that social connectedness in because we were
- 7:17also talking about group classes and attending classes and
- 7:20meeting different people, especially if you are moving
- 7:23countries, living in different places and then also avoiding
- 7:26those risky substances. So these are things that, yes,
- 7:30make sound easy, but that behaviour change is really hard.
- 7:35Yeah, it is really difficult. And especially when people are
- 7:38busy, and especially as it's so easy to not do that, to not eat
- 7:42healthily, to not exercise frequently, to not think about
- 7:45our sleep. And you know, you're one of the
- 7:47few doctors that actually practices what they preach.
- 7:52I hope you don't mind me staying there.
- 7:53Thank you. It's taken me a while, I'm being
- 7:56through my own journey and I see what works now and I don't want
- 7:59to go back. No.
- 8:01So when did you really change? I'm going to say sort of pre
- 8:05COVID, I'm being fit and healthy, you know, with a lot of
- 8:08sport, but it's different to really being optimized and
- 8:12feeling that difference, especially with competitive
- 8:16sport and also being able to keep up with, you know,
- 8:20teenagers. Well, your tennis.
- 8:21Tennis is your main. I mean, because that's what I
- 8:24sort of hold there in the middle and what I do is around that to
- 8:28make sure I'm strong enough. I've got that endurance.
- 8:31So my muscle mass, my strength, my endurance and my recovery
- 8:34after. Because at the end of the day, I
- 8:36don't want to be playing a three hour tennis match at 2:00 PM,
- 8:39which is what usually happens in Singapore for the matches and
- 8:43then have to spend the rest of the weekend playing catch up.
- 8:47So it's about how do I, what do I need to do for me as an
- 8:50individual? And this is where precision
- 8:51medicine comes into play because it is very individual and it's
- 8:55how do you create that environment for you in a way
- 8:59that is sustainable in the long term.
- 9:01It's sustainable is really, really important because, you
- 9:05know, my lifestyle's changed a lot and I feel very strongly
- 9:09that I can't practice and preach something differently.
- 9:14I can't be saying to patients, come on, you need to exercise.
- 9:16If I'd never exercise, it just doesn't work.
- 9:19But you know, nobody feels worse if they eat better.
- 9:22No one feels worse if they exercise.
- 9:24But I was having this, this, this discussion with my daughter
- 9:27actually last night, because like I said to you earlier, she
- 9:30took me to an exercise class last night in London and it was
- 9:33quite hard. And I think most of the people
- 9:36in the class were between like 20 and 25.
- 9:39So I was definitely more than double every age in the class.
- 9:44And it's inside Louis what it is.
- 9:46And I thought, Oh my God, I've really, I've got a show, I've
- 9:48got a show and I, but it was great and I really enjoyed it.
- 9:53But then she was saying, oh, let's go to a spin class next.
- 9:55Now I can't like I, I used to cycle up, but it often triggers
- 9:59migraine for me if I do a really high intensity work out.
- 10:03So I said CVI, I'll do other classes, but I just really
- 10:05careful. I have to make sure my head's
- 10:07completely clear and I've just come out of having a three day
- 10:09migraine. So the minute I'm still a bit
- 10:11careful, but it's very, very individualized.
- 10:14Whereas other people like my husband can go for a cycle and
- 10:17he won't have had anything to eat.
- 10:19He'll be absolutely fine and, and really go for it.
- 10:22And I think that's where like we've got privilege of knowing
- 10:25our patients and know what works for them.
- 10:28And also to just do it in stages.
- 10:31Because if if people heard like the weights that you lift and
- 10:35the exercise you do, they would be so intimidated.
- 10:38They probably would do nothing. But you are so wonderful the way
- 10:41you educate and bring your patients on their journey.
- 10:45Thank you. That for me is what I really
- 10:48enjoy. And I know, OK, I, I'm a family
- 10:51physician, I'm AGP. And I think that's the beauty of
- 10:54this is you can have somebody sit in your consult room for two
- 10:59years on and off and then one day show up and go, I think I've
- 11:04finally heard what you've said. I'm ready and then you're ready
- 11:06to go. And that's the beauty of it is
- 11:09building those relationships and also working through the changes
- 11:14that can happen. There's no one-size-fits-all.
- 11:16Things change. Similar with perimenopause and
- 11:19all the hormonal shifts and changes.
- 11:21We can get it right And then six months later it's off again.
- 11:26And then we've got to tweak and change.
- 11:27And this is where it's more often art than a science as
- 11:30well. And getting to know the patient
- 11:32sat in front of you makes such a big.
- 11:34Difference, absolutely. And, and I think it is really
- 11:36important when we think about hormones, cause I've had
- 11:38patients who are really sporty, really fit.
- 11:41And then they say to me, gosh, I, my stamina is reduced.
- 11:44My post recovery is taking a lot longer.
- 11:47I just feel absolutely exhausted doing very little training.
- 11:51What's going on? And then you realise they've got
- 11:53no testosterone and, and, or they're not eating enough
- 11:57protein. You know, there's lots of
- 11:58things. And I think there's general
- 12:00physicians. We're not just looking at one
- 12:03thing, we're looking at everything.
- 12:04And that's sometimes missed in medicine, isn't it?
- 12:07It is. And it's also assuming that it's
- 12:10one thing or another. Absolutely.
- 12:12I have patients where they've been stable on their hormone
- 12:15therapy for years and then present one day going, I think
- 12:19my hormones off and you said they're going hold on.
- 12:21It doesn't quite make sense. And then you dig and you dig and
- 12:24you dig. I'm a bit of A and it's finding,
- 12:29you know, a thyroiditis and hold on, let's manage this because I
- 12:33could very easily just throw more and more hormones at this
- 12:36person, at my patient. It's not going to change
- 12:38anything, but it's finding that underlying.
- 12:42And this is where, yes, the buzzwords at the moment, it's
- 12:45menopause, it's hormone therapy, it's longevity, but at the end
- 12:50of the day, it's about your overall health and well-being.
- 12:54And how to? Get on top of that with your
- 12:58health screening, ruling things out, finding you know, knowing
- 13:02what your biomarkers are. Is there inflammation?
- 13:05Are you pre diabetic? So, you know, non diabetic
- 13:08hypoglycemia, what's your fasted insulin like?
- 13:12These are things and then looking at cardiovascular risk
- 13:15and we have so many extra parameters we can utilise now,
- 13:19but it's tailoring it to that person rather than just doing
- 13:22again every test under the sun. It's really important, even
- 13:24though I've got a patient at the moment who's perimenopausal, so
- 13:28it's always difficult to get there and she's had a lot of
- 13:31mental health issues. It's been really scary for her
- 13:33but really difficult to get the right dose.
- 13:35And recently after about 5 months, I think I just got
- 13:38there, but she's still been not right.
- 13:41But then her iron, her ferrity level is really low and she's
- 13:44tried iron supplements and she can't tolerate them at all.
- 13:48But she's also got endometriosis.
- 13:50And so often when people have active anything that's
- 13:53inflammatory, but especially endometriosis, their iron will
- 13:56be falsely raised. So her low iron is probably even
- 13:59lower. So I'm trying to get her an iron
- 14:01infusion at the minute and there's so much pushback because
- 14:04it's not quite the level. It's like too higher than it
- 14:08could be for the guidelines of the iron.
- 14:11And anyway, they've just finally agreed to do it.
- 14:13And I'm, I'm just thinking, I don't think her mental health
- 14:17and her physical health will be optimized without.
- 14:20I can give all the hormones I like, but she just needs iron
- 14:23and she eats meat and you know, so but again, it's looking at
- 14:27everything. So when people say don't do
- 14:29blood tests, well, actually we don't just do hormone blood
- 14:32tests. We look at everything.
- 14:34Overview. Yeah, it's so important.
- 14:36Iron, I mean iron, vitamin D, these are.
- 14:38Really crucial fixes. Right, looking at B complexes,
- 14:44why not? Yeah, right.
- 14:45First thing is do no harm. Yeah, right.
- 14:48It's. Shared decision making, it's
- 14:50education, it's conversation and it's monitoring.
- 14:53And yes, in Singapore, I'm in a very privileged position to be
- 14:57in private practice where I can do all of that, compared to NHS
- 15:00work where, you know, it's a lot more demanding.
- 15:03And trying to stay on top of 3040 patients you're seeing
- 15:07every day is not always easy. But again, it's how do you just
- 15:11keep that relationship, sort of keep building on those
- 15:15relationships and trust and that education.
- 15:18Piece. But I look back at some of my
- 15:19patients in general practice and I know I gave them a disservice
- 15:23because I wasn't thinking long term.
- 15:27I wasn't thinking how to prevent their next urinary tract
- 15:29infection, for example. I was very reactive.
- 15:32I was do I need to dipstick? Do I need to send it for urine
- 15:35culture? Do I need to give them
- 15:36antibiotics? Do I give them three days or
- 15:38seven days? Do I need to give them
- 15:39prophylaxis? But I didn't think about why
- 15:42were they getting the infection? Why is a 62 year old lady coming
- 15:45for the third time with a urinary tract infection?
- 15:47I didn't even ask if she had any vaginal dryness or soreness,
- 15:50didn't even ask when her period stopped.
- 15:53And of course if I'd given her some vaginal hormones, I
- 15:55probably would have never seen her again in the clinic.
- 15:57But I didn't think. And I think that's the problem.
- 16:01Often it's very knee jerk. Whereas when you've got time,
- 16:04and I think that's when you say your privilege, working
- 16:07practice, my privilege I think, and I think you'll agree as well
- 16:11is that we've got time. So yes, you've got access
- 16:13probably to more tests, but you've actually got time to work
- 16:17with your patients, which it's. That, for me is a privilege.
- 16:22It is, isn't it? It's having an hour for a
- 16:24patient, A new patient. Yeah.
- 16:26Just sit back and listen. I spend most of my time
- 16:28listening. But you get to really understand
- 16:31what the how to prioritise, how to work with them, how they can
- 16:35work with you. And every patient is really
- 16:38different. And at different stages of
- 16:41making decisions as well. I have some women who come in
- 16:44going, yeah, I'm ready, let's go.
- 16:45And I'm like, oh, OK, hold on a second.
- 16:47We still need to make sure you're not up to date with your
- 16:49screening. Let's get all of that done.
- 16:51And there are things we need to work on.
- 16:53But it's it's that those building blocks, right?
- 16:56As I said, you can't really out exercise a poor nutrition.
- 17:01And if you're not? Sleeping enough, it's very hard
- 17:05to then be able to function and do what you need to do.
- 17:08It's like waiting through treacle rather than just walking
- 17:11outside. Yeah.
- 17:12And it's, it's interesting because you gave the most
- 17:14amazing presentation and in March at our conference that we
- 17:18did, and it was about lifestyle medicine for healthcare
- 17:21professionals, wasn't it? And lots of people came up to me
- 17:24afterwards and they said, wow, like this is incredible.
- 17:28And I was like, obviously it was the most amazing talk, but
- 17:31actually a lot of it was stuff that.
- 17:33You made. I've known for ages, but it
- 17:36actually when I was looking at the audience and seeing people's
- 17:39responses, I thought, gosh, people don't know like basics
- 17:43because in medical school we're not taught basics about
- 17:45nutrition and exercise, are we? And then if if you're not
- 17:48personally interested or you've not read, you can see that, you
- 17:53know, you think that a ready made sauce is going to be fine.
- 17:57You think that low fat yogurt is going to be healthy because no
- 18:01one's they told you the obvious people don't understand the gut
- 18:05microbiome and how that has affected your mental health.
- 18:08And it makes you realise actually that it's not just
- 18:12people and our patients we need to educate, but other healthcare
- 18:15professionals because this is very basic.
- 18:18Like it's not sexy medicine. It's not, it's not cutting
- 18:21people open. And but it, it is.
- 18:23I love the way you say it's the foundation.
- 18:25It's the foundation. And, and I think like sometimes
- 18:28with my work, people think what I do is prescribe hormones and
- 18:32it's like, hang on. And do you not think that
- 18:34hormones will start, We know, work better if you've got less
- 18:37inflammation in your body, if you've got that foundation.
- 18:40But also, you know, if someone had diabetes, they had raised
- 18:43blood pressure, they had any condition or they were really
- 18:47fit and well, that that sort of foundation has got to be there,
- 18:50hasn't it? It does.
- 18:51And this is where actually different people at different
- 18:54stages and then behaviour change.
- 18:57And as doctors, I'm going to say we're natural health coaches,
- 19:01right? And yes, there are extra sort of
- 19:03exams etcetera you can do in a lot of learning.
- 19:06But it's part and parcel of what we do is we are coaching our
- 19:11patients through their own health Chin.
- 19:13And OK, on the NHS you have to switch every 7 to 8 minutes.
- 19:19Private practice, you've got more time, but it's still, it's
- 19:23how do you actually tailor something?
- 19:26You know, I'll have one patient go, right, I'm ready.
- 19:29Tell me everything I need to do, I'm going to do it.
- 19:31And you know, that you can actually come up with a plan.
- 19:34And we do written plans and we follow through on it and others
- 19:38where if I give them more than one thing, it's not going to
- 19:41happen. And they're going to come back a
- 19:43few weeks later not having done that and feeling even worse for
- 19:46wear because you're going to feel that guilt of, oh, I only
- 19:49had one thing to do and I couldn't do it.
- 19:51But it's how do you, in a stepwise approach, build it?
- 19:54And then when you get it right, boys, it's satisfying.
- 19:56Yeah. Because you're going through the
- 19:58journey with your patient, which is great fun.
- 20:00But do you think we're making progress, do you think?
- 20:03I have to say, we are, I know, I know, I know, I've, you know,
- 20:07for me, I want to make sure that the glass is always half full,
- 20:10right? And this is part of all the
- 20:12education work we do, the writing, you know, with the
- 20:16Healthy Longevity Medicine Society, we've got a Women's
- 20:20Health and hormone therapy group that we're writing about how
- 20:25hormone therapy needs to be utilized moving forward.
- 20:28And there are so many papers, so much research out there putting
- 20:32it together and basing it on the 12 hallmarks of aging, thinking
- 20:36about how it can be a Gerra therapeutic, a Gerra protector.
- 20:40So how do we protect ourselves as we age is key, right?
- 20:46And it's from an education point of view, it's also giving all
- 20:50our colleagues the right information.
- 20:54And yes, different, you know, different doctors will practice
- 20:56at different levels because we all have different interests.
- 20:59But it's how do you get everyone thinking in a way of going
- 21:02right? How do I get the person sat in
- 21:04front of me feeling as good as possible?
- 21:08Because you've got, I mean, it's going for gold when it comes to
- 21:11quality of life. Yeah, and I think I was.
- 21:13I was with my daughter last night and she's 21 and her
- 21:17generation and lots of them don't drink nearly as much as
- 21:21when I was 21 and not smoking the same way.
- 21:23But she's buying avocados, She's got pomegranate.
- 21:27She's thinking about her food in ways that I certainly didn't
- 21:30think about when I was 21. And I think, well, if she and
- 21:33she's learned it herself, really, because there's only so
- 21:36much you can tell your children and you know she's watching it,
- 21:40but also she knows she feels better when she eats better.
- 21:42And that's, I think that's the most magical thing if you learn
- 21:46that as an individual because he'll carry it with you.
- 21:49But when we think about preventing diseases, it we
- 21:53always know about, like you say, those foundations.
- 21:56But when we're talking about hormones, that's still being
- 21:59forgotten. And you know, people have this
- 22:02accelerated ageing when they become menopausal.
- 22:05And we've known it for many, especially when you look at the
- 22:07data, like Water Rockers data, when women who have a surgical
- 22:11menopause at a young age, so women in their 30s have their
- 22:15ovaries removed, their hormone levels decline overnight, and
- 22:18then they have this increased risk of diseases.
- 22:21And we know sort of metabolically, there's increased
- 22:26inflammation, there's worsening of very basic biological
- 22:29processes because these hormones are biologically active.
- 22:33And that's been forgotten. But we've known about it for
- 22:36decades. So this isn't new science.
- 22:39No, I think it's also just historically what's been done
- 22:44and the way it's been done and comparing now to then.
- 22:47I think we need to move on from the Women's Health initiatives.
- 22:51We need to move on and we need to go right.
- 22:53What do we have access to now? We've got modern hormone
- 22:57therapy. We've got transdermal Easter
- 23:01dyne, right? We've got micronized
- 23:03progesterone, we've got testosterone.
- 23:07So how do we utilize modern, I'm going to keep saying this,
- 23:11modern hormone therapy for the person sat in front and there's
- 23:15no one-size-fits-all. But we need to start thinking
- 23:19about that prevention piece and the precision medicine piece,
- 23:23tailoring it to that person. And where we can do this at a
- 23:26population level is again, that foundation of lifestyle
- 23:30medicine, plus the education work that goes with it.
- 23:34So each and every person has choice.
- 23:37And you were talking about your daughter and how she is eating
- 23:41and exercising. And I'm seeing that so much more
- 23:43because we do a lot of work in adolescent health as well.
- 23:46And from a sports and performance point of view, with
- 23:50access to social media, AI platforms, and lots more
- 23:55conversations taking place, adolescents, teenagers have a
- 23:58lot more information than I ever did.
- 24:01For sure. Right?
- 24:02And they're utilizing that because they're seeing the
- 24:04benefits. They want to be optimized.
- 24:05They want to feel well. So even when I talk to families,
- 24:10it's going right what you do as a parent, if your teenager's
- 24:17tweens see you eating in a certain way, doing things in a
- 24:21certain way, that's their normal.
- 24:23Which means when they're going through exams or life stresses
- 24:27or whatever happens, they're not reaching for ultra processed
- 24:31food, they're reaching for good whole food, predominantly plant
- 24:35based, prioritizing things that really make them feel better
- 24:39because they know the impact and that behaviour change then is
- 24:44there normal? So you're not having to force it
- 24:49later on in life, which is what we've had to go.
- 24:51Through yeah, it's so important, I think, you know, accepting
- 24:55things, normalizing conversations, normalizing
- 24:58behaviours is, is so important with our patients.
- 25:02But it's, it's just a shame that it's sort of been lost and, and
- 25:07even thinking about the health preventative or the disease
- 25:10preventive effects of hormones. I was reading, there's a
- 25:13conference that was in the 1970's, the 1974, it's a big
- 25:17conference. And it was, it was about healthy
- 25:20ageing and the role of hormones. And, and they've really well
- 25:23written notes. I, I had to get the, the book
- 25:27from the Royal Society of Medicine because it's impossible
- 25:29to, to get online. And, and anyway, it's, it was
- 25:33talking about the disease, preventative effects for
- 25:37osteoporosis, for heart disease, for cognitive decline,
- 25:40Alzheimer's, dementia and probably cancers for hormones.
- 25:47And these, this was a really pivotal because before that time
- 25:50in 1941, as you know, Professor Albright announced about the
- 25:56osteoporosis and the bone strengthening of effects of
- 25:59hormones. And people were like a bit, not
- 26:01sure, but this was really like, actually guys, hormones can
- 26:06reduce disease. And then it sort of seemed to
- 26:10have been lost again and it's such a shame.
- 26:13And we need to bring that. Back which is.
- 26:15Part of the work. That's happening, absolutely.
- 26:18Is to bring that back and also remembering that 50% of the
- 26:21world's doctors are primary care physicians and thereabouts.
- 26:26And it's about things written in a logical way and with the
- 26:32science that we have. And there's so much research.
- 26:35As I said, the 1st paper we wrote, we had to to actually cut
- 26:38down. And then we had to cut down in
- 26:40the number of references as well.
- 26:41But there's so much science. There's so much basic science as
- 26:45well, which is really important. And, and, and The thing is, I
- 26:49think, you know, often I feel very sad because menopause is
- 26:51denigrated to bad symptoms. And there's all this discussion
- 26:55is how bad are your hot flushes or how many night sweats do you
- 26:59have? How many times do you have
- 27:00broken sleep? Whereas actually as the
- 27:02physician who wants to prevent disease, we need to be thinking
- 27:06about right, why do we give HRT and the British national
- 27:11formula, the BNF, which is our sort of Bible, if you like, go
- 27:14to is very clear that there are two license indications for
- 27:18estradiol. For example, the patches 1 is
- 27:21for treatment of menopausal symptoms.
- 27:23So actually not perimenopause and we do give it like
- 27:26perimenopause, but just to add, it's fine to give drugs out of
- 27:30license. But the second indic is for
- 27:32prevention of osteoporosis. And so when we're thinking about
- 27:37this discussion about what symptoms do you have and if
- 27:40you've got living in different countries or different
- 27:42ethnicities, do you experience different symptoms?
- 27:45I think that's an interesting discussion.
- 27:47But the most important thing is think about the diseases that
- 27:50are affecting people. And so I'm sort of thinking
- 27:53about in Singapore, osteoporosis rates are really increasing, but
- 27:59we've got a treatment that's licensed for prevention of
- 28:02osteoporosis, yet most people in Singapore, but also in the UK
- 28:06and globally and not being prescribed hormones for that
- 28:08reason, are they? But that licensing is in the UK,
- 28:11Yeah, right. So it's also looking at regional
- 28:15guidelines because at the end of the day, it's going right.
- 28:18What does my regional society say?
- 28:22Right. What does my local society say?
- 28:24And that's something that's really changing because the Asia
- 28:28Pacific Menopause Society as well, looking at the federation
- 28:32guidelines, which have just been updated, and then being utilized
- 28:36for the region in AIPAC is huge and having a lot more education
- 28:41events. So there's going to be an event
- 28:43run by the Singapore Menopause Research Society next March and
- 28:48just a lot more education work happening.
- 28:50And I think that's key because it's getting the doctors on
- 28:56board. Absolutely it's.
- 28:58Getting the clinicians on board, it's also looking at the next
- 29:01generation, right? So medical school, having
- 29:04conversations is part of the communication teaching that we
- 29:07do as well. And similar here, even with the
- 29:12British Society of Lifestyle Medicine, really looking at how
- 29:17we get lifestyle medicine taught at medical school as part of
- 29:21curriculum, as part of GP training.
- 29:24And I'm going to say everyone needs to that this is basic
- 29:28knowledge and you can delve into it in more detail, but at least
- 29:33knowings you can pick things up. But it's also the collaboration
- 29:36effort, right? It's working together.
- 29:40And I think the more we can work together within the
- 29:43specialities, within group practices, wherever in the world
- 29:48they can. I love the fact that I can pick
- 29:50up the phone and call somebody in the US or hear, you know, the
- 29:54conversations we have then in Australia.
- 29:57It's just having that network. And it's not about fault.
- 30:02It's just going right, here's what I'm thinking.
- 30:06What do you think? Can I and how do I improve my
- 30:10practice? And I think that is changing
- 30:13even over the last couple of years.
- 30:14You know, there's there's a lot of us in lots of different
- 30:17countries that are really working often behind the scenes
- 30:20together. And we're, you know, joining the
- 30:24dots that often haven't been there.
- 30:26We're realizing that we're not working alone.
- 30:29And then it just helps our patients as well because you
- 30:32know, you never get something 100% right.
- 30:35And it's a journey with our patients that you say.
- 30:37So there's there's loads that we're doing, there's loads more
- 30:39we can do. And I and I think bringing those
- 30:41people that want to learn is part of it as well.
- 30:44The people that don't want to learn, it doesn't matter.
- 30:46They can do other things, but there's some really keen people
- 30:49to be joined up in this space. So I so I'm very grateful for
- 30:53you being here, Tash, but I just need to end for three take home
- 30:57tips. You know they're going.
- 30:58To I know, I know it was coming. What are the three things that
- 31:01you would say if I was coming to you as a patient that said, you
- 31:04know what? I don't exercise.
- 31:06I know I don't eat well. Like what are the three things
- 31:09that I should do that's going to help my future health span?
- 31:13It's choose one thing, start somewhere, right?
- 31:17And that could be nutrition for one person.
- 31:20It could be I'm going to have one drink less when I go out.
- 31:24But one thing has a hugely beneficial ripple effect.
- 31:29And then it's, it's, it's once you pop, you can't stop, right?
- 31:34So you, you, you do one thing and you go, oh, actually I feel
- 31:36I've slept better. Let me try this next thing.
- 31:40And it's working with that clinician who, you know, can
- 31:43guide you on that. Secondly, ageing is inevitable.
- 31:49However, what can you do to optimize your quality of life?
- 31:54And that's going to be different for different people.
- 31:57And I don't, you know, expect everyone to be lifting really,
- 32:00really heavy weights. If you've never done it, please
- 32:02don't just go to a gym and start trying to deadlift and squat and
- 32:06do pull ups. Start somewhere.
- 32:08Start with some home exercises, start with a wall, sit for 30
- 32:13seconds whilst your kettle is boiling.
- 32:15You know, these are things that it just keeps building up.
- 32:19And also, I really want not just women, I want people to advocate
- 32:24for themselves, right? We need to push for up to date
- 32:29guidelines and to stay on top of that and think of a guideline as
- 32:33a guideline, right? Look at the latest research,
- 32:36look at the latest evidence and collaborate, have conversations
- 32:40because we as clinicians need to make sure that our patients are
- 32:44getting the best care available to them and we can't do that
- 32:47alone. Yeah, I really like that.
- 32:49So it's not just patients being advocates, it's doctors being
- 32:52advocates for their patients. Great way to end.
- 32:54Thank you so much. Thanks, Louise.
- 32:56Thanks for having me again.