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Once Is Not Enough: Round 2 on Therapeutic Insights

In episode 61 of Derms and Conditions, our host, James Q. Del Rosso, DO, presents a self-made episode where he clarifies key points on many therapies relevant to every-day clinical

practice. First, he discusses topical alpha-agonist therapy for persistent facial erythema (PFE) of rosacea. Long-term data shows that daily use of either topical oxymetazoline or

brimonidine appears to “reset” (lower) the baseline level of PFE in patients with rosacea.

Next, he talks about sub-antibiotic dosing of doxycycline and how its anti-inflammatory properties, including support of the dermal matrix, can be…

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