Targeting TIGIT: Understanding New Approaches for Inhibiting the Immune Checkpoint Pathway

Decera Clinical Education Oncology Podcast · Apr 7, 2022 · 20m

In this episode, Jyoti D. Patel, MD, and Diwakar Davar, MD, discuss several studies investigating agents targeting TIGIT, an emerging immune checkpoint target with promising early-phase clinical trial results. The episode includes a comprehensive explanation of TIGIT, how the TIGIT pathway functions, and the potential role of TIGIT inhibition for the treatment of cancer, including analyses from ongoing clinical trials such as CITYSCAPE, PACIFIC-8, ARC-7, and SKYSCRAPER-01.

Presenters:

Jyoti D. Patel, MD

Professor of Medicine

Division of Hematology and Oncology

Medical Director for Thoracic…