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Liquid Biopsy: Current Applications and Future Direction
This comprehensive review examines the evolution and clinical potential of liquid biopsy, a non-invasive diagnostic method that analyzes biomarkers within bodily fluids. The text classifies primary biomarkers such as circulating tumor DNA, intact tumor cells, and extracellular vesicles, while detailing the high-sensitivity technologies like digital PCR and next-generation sequencing used to detect them. In oncology, the authors highlight how these tools facilitate early cancer screening, the prediction of therapeutic responses, and the real-time monitoring of minimal residual disease or drug…
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