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When a Single Carbon Killed a Drug: The DOET Molecule's Lost Promise

When a Single Carbon Killed a Drug: The DOET Molecule's Lost Promise

A single-carbon change turned DOM into DOET - a molecule that produced clear-headed euphoria in one test and deep lethargy in another - yet it never reached patients because a separate street crisis exploded. How did a San Francisco outbreak tied to an entirely different compound bury a promising pharmaceutical before science could finish it?

In this episode, we trace the path from a Dow Chemical lab to a Schedule I classification, following patent filings, a contested disclosure to a clandestine manufacturer, and a halted…

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