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PAH and Hypoxia Exposure Result in Mitochondrial Dysfunction in Fish

Zebrafish exposed to polycyclic aromatic hydrocarbons (PAHs) in water with inadequate oxygen, or hypoxia, can experience a broad range of effects on the mitochondria, according to an NIEHS Superfund Research Program (SRP)-funded study. Changes to the function and integrity of mitochondria, which are organelles that make energy for the cell, can disrupt metabolism and reduce organism fitness and performance.

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