275-Developmental Trajectories of Mouse Visual Cortex
The paper reports the creation of a comprehensive transcriptomic and epigenomic cell-type atlas for the developing mouse visual cortex, spanning from embryonic to adult stages. Researchers employed single-cell RNA sequencing (scRNA-seq) and single-nucleus Multiome (snMultiome) to map the continuous diversification of excitatory, inhibitory, and non-neuronal cell subclasses, providing an unprecedented molecular timeline of development. The atlas systematically categorized thousands of differentially expressed (DE) genes and differentially accessible (DA) chromatin regions associated with…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.