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Under Pressure: Catching Cases of MSCC

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The cells of a malignant tumour are restless. Every so often, one wriggles free and breaks off. It’s almost certainly doomed: if it’s not destroyed by immune cells, it will likely succumb to fluid shear stress as it’s dragged through narrow vessels, or just undergo programmed cell death [1].

But some do make it to the spine and colonise it; we then call them metastases. Why so often the spine and not, say, the tibia or the deltoid?

People often blame Batson’s plexus: blood draining back to the heart can be…

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