605-D-LMBmap: Automated Pipeline for Whole-Brain Mapping
The paper introduces D-LMBmap, an integrated open-source software suite designed for the automated 3D mapping of whole-brain neuronal connectivity using light-sheet fluorescence microscopy. This framework addresses critical bottlenecks in neuroimaging by offering advanced tools for automated axon segmentation, brain-style transfer, and multiscale 3D registration. By utilizing deep neural networks and innovative data augmentation, the system significantly reduces the manual labor typically required for annotating complex axonal projections and identifying anatomical regions. It also employs a…
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