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Microsoft AI Hit 83% on Cases Where Doctors Got 36%

On medicine's hardest puzzle cases, a panel of debating AI agents got the right diagnosis more than twice as often as generalist doctors with internet access.

Microsoft AI Beats Generalist Doctors on Hard Diagnoses, October 24, 2026

A new peer reviewed study in Science reports that the Microsoft AI Diagnostic Orchestrator, a virtual panel of debating AI agents, solved 83 percent of complex New England Journal of Medicine cases versus 36 percent for generalist physicians. Chris and Laura unpack how much of the gain comes from the underlying models, why the cost savings matter, where the system…

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