Latest / Ageless and Timeless Podcast® / James White CEO and Owner KBMO Diagnostics.
Transcript
- 0:10Good morning everyone. This is Michelle Hughes from Ageless and Timeless. We're doing
- 0:15audio only today with our wonderful guest James White, who is the CEO of
- 0:21KBMO Diagnostics, which is in Hope Gale. Probably never heard of that,
- 0:27but Hope Gale. Is that how you say it? Hopedale, Massachusetts?
- 0:30Right, yeah, that's right just on the just outside, just outside both.
- 0:35Yeah, so you know, I grew up and I told you this,
- 0:37but I grew up in South Natick, which is right right well as
- 0:43the college. But I've never heard of Hopetale, sorry about and I lived
- 0:48there for what twenty twenty years until I went off to our nineteen years till
- 0:53I went off to college, So I'm sorry about that. It must be
- 0:56a very little town. It is. It's very cute, but but nowadays
- 1:00it's just don't pull any five. It's a good spots, so okay,
- 1:04so it's easy for people to get you right in the technology corridor then,
- 1:08huh exactly exactly just off the Mask Pike, the dreaded mass Pike. So
- 1:14yeah, yes, well you know, I have a funny story about that
- 1:17because when I met my husband, who we met at fourteen, he was
- 1:23going to Harvard and I was going to the University of Massachusetts and Amherst.
- 1:26But our parents didn't want us to keep seeing each other during college. They
- 1:30thought there was time after eight years to you know, just branch out and
- 1:36have a little dating experience. So we didn't want to let them know that
- 1:38that wasn't happening. And my father bought me a car for using a campus,
- 1:44but he didn't know that every weekend I was driving that car on the
- 1:47mass Pike the Native exit, and every time I would go there, I
- 1:53would beholding my breath that my father and mother would not see me because they
- 1:57were out shopping somewhere or so. That's a very Massachusetts version of star Cross
- 2:02love. There we go, That's what it was. But they did,
- 2:07and we actually ended up, you know, obviously violating their wishes. But
- 2:12yet we went through all through college and then and then got married, so
- 2:16it was it was a happy ending. But that Mathpike always reminds me my
- 2:23weekly trips to King So James, welcome to Ageless and Timeless. So we're
- 2:30so happy. You know, I've been looking forward to this since I met
- 2:34you at the eighth for M show in December and well, I didn't meet
- 2:38you, but I met your people and did your little, amazing little blood
- 2:43trick that tells you so much information, which we'll get to in a moment.
- 2:47But the reason I've been looking forward to this for so since December is
- 2:52that I wanted to do a microbione series, knowing how important this is.
- 2:58The subject has become m in the minds and in lives of many people who
- 3:04are health conscious. So um, and I am having doctor Rob Silverman in
- 3:08two weeks. Uh, and I know you two are collaborating many courses another
- 3:14microbiome or at least say um, at least say the GI tracked you know
- 3:20they're we're both very experts. So let's start by telling us more about you
- 3:25first, because people want to know who you are, how where did you
- 3:30come from? And how did you get here? Yeah? So I um
- 3:35I, as you can probably tell from my accent, I had to tell
- 3:38our home from East Boston on the basis, probably further east than most people
- 3:43imagine. So I'm roaging from the UK and h we moved over here about
- 3:49nineteen years ago, so nearly twenty years ago. And my children don't quite
- 3:54found something tames me they've got the Boston accent, but that's okay, uh.
- 3:58And we've really enjoyed living over here. And in that time I was
- 4:02running a UK public company and we had operations in beautiful Pasadena, Atlanta and
- 4:10then Boston as well, so we moved over here and I kind of felt
- 4:14that New England was a great place to bring up our children, and so
- 4:16we did that, and that really is the is the foundation of the name
- 4:21of the company. So it's called KBMO Diagnostic. K is for Kat and
- 4:26my wife, The is for Ben, my eldest son, Emma is for
- 4:29Max, my middle son, and OHS for Olivia, my daughter, and
- 4:32so you know, we all have bosses, and they're my four bosses.
- 4:36So it was kind of it seemed like a good way of naming my company
- 4:40to have it named after the foremost important people in my life. So that's
- 4:46how we kind of got here twenty years ago running a UK public company,
- 4:50which was we sold off a number of the divisions to various companies like Roche
- 4:57and so it worked went very well, and we weren't very keen to going
- 5:00to head back to the UK. We really liked liked living in Massachusetts and
- 5:04so I came across a company called, at that time Brendan Bias Science that
- 5:09was being headed up by my technical founder of Kuma generman called doctor Brent Dorville,
- 5:14who's not insignificant claim to fame, was invented the first rapid HIV diagnostic,
- 5:20and he'd moved into this kind of whole area of food sensitivity. And
- 5:27we can talk about the difference between allergy sensitivity and all these things, but
- 5:30he kind of moved into this area, and so he and I kind of
- 5:33got together and partnered about ten years ago now, So that's really how we
- 5:39got here. It was originally running a different business and then kind of once
- 5:44we've kind of sold that off, moved into this area of food sesitivity.
- 5:48So that was that, that was the genus. And again there's so many
- 5:53bright, intelligent people here in Massachusetts and the US as a whole who were
- 5:58looking at healthcare. But see, as you mentioned with your husband and Harvard,
- 6:01there's a many universities in and around this area, and so we've really
- 6:05enjoyed being here and you know, talk about a bit more about our company,
- 6:10and you know, some of our great employees that we've we've had a
- 6:13who were all from this from this area. How did you not get a
- 6:16Boston accent? But your kids did? It's so funny. It's in the
- 6:23UK. It's a bit more common than I think over here. But generally
- 6:25people have what they call a gap here, which as you leave high school
- 6:28and you have a year of kind of bumming around the world. And so
- 6:30a lot of my friends who went kind of through fire Australia came back sounding
- 6:34like, you know, they've grown up in Australia. I think you get
- 6:36past a certain age and you're kind of stuck with what you're stuck with.
- 6:41So I'm stuck with this one. So I guess I'm okay with that.
- 6:44Well, you know, just as a segue, when I came to San
- 6:47Francisco, which was many many decades ago now, but so I consider myself
- 6:54a San Francisco local, not a native, but a local. But anyway,
- 6:59when I came here, the people that I met couldn't understand me.
- 7:02They always made fun of me. And you know, I had a really
- 7:06really bad I mean not bad, but you know, a very strong yeah.
- 7:12And you know, I look, you grow up there, that's what
- 7:14happens. I don't know how I got rid of it. Every once in
- 7:17a while, maybe if I have a glass of champagne or something, I
- 7:21have people say, oh, I hear that Boston accent. But mostly it's
- 7:27gone. But I'm so grateful for that. When I come back to see
- 7:30my family and I hear that accent, I think, I can't believe that
- 7:34I actually have that accent. And it's a great chim That's a good one.
- 7:40But they know where they come from and they're proud of it, so
- 7:46that's a good thing. Yeah, that's good. Well, let's talk about
- 7:49ABMO that and I want people that are you know, our viewers, well
- 7:55today it's our listeners. I want them to understand what exactly your testing can
- 8:01do for them. So we're going to that's our goal for the podcast.
- 8:05But in the meantime, I'd like to hear a little bit the science and
- 8:11maybe start with that open ended question first is what is the difference between or
- 8:16among those terms which people hear all the time food allergy, food intolerance,
- 8:22food sensitivity. If those three were put on a screen, how would you
- 8:28differentiate. Yeah, that's a great question, and unfortunately the medical community are
- 8:35as guilty as as you know, as consumers in terms of the kind of
- 8:39inter use of those three terms. So I think it's it's a fair place
- 8:43to start in term the kind of giving people our understanding of how they differ,
- 8:48to make to make it more sense of it. And so you know,
- 8:50allergy is generally what we describe as an IgE reaction, and it is
- 8:56kind of cause and effects. So think of you know, child eats peanut,
- 9:01instant reaction and generally are very severe reactions. I think things like prophylactic
- 9:05shock. So an allergy is a immediate response and generally a very severe outcome
- 9:13to it. So that's the allergy. And as I remember hearing from one
- 9:18provider, he was an MD, he said, you know, generally,
- 9:20James, I don't test for people over twenty four allergies. If they're still
- 9:24here at twenty, then they don't have an allergy, which is maybe it
- 9:28is the work on his bedside manner, but it was kind of certainly stuck
- 9:33in my mind. And then if you think of food sensibly, which is
- 9:37what we do. Again, it's an immunological response, but it's a delayed
- 9:41response. Up to seventy two hours is delayed, so that makes it much
- 9:46harder for a patient or a provider to work out which food patient might have
- 9:50consumed in the last seventy two hours is leading to the symptoms that the patients
- 9:56present with, and those symptoms, to be honest Michelle, are many in
- 10:00vary which makes it harder for them to work it out. So the differences
- 10:03is the time as well as severity of response. And naturally, the best
- 10:07way to think about it is an allergy is instant, the sensitivity is delayed,
- 10:13and generally those symptoms are much more varied. So again they may be
- 10:18kind of non specific author immune type reactions and arthritis things like that. So
- 10:24there are there are many and varied versus analogy which is more prophilectic, ship
- 10:28shot and more severe or severe. So what does I G E stand for?
- 10:35And what does I G so's It's just an immunoglobulin E and are immunoglobulin
- 10:41g SO again an E. It's just a different pathway as it were in
- 10:46terms of you think of sometimes like cardiovascular testing, they'll test you form a
- 10:52number of different cardiovascular markers and for the IgG IS there's one pathway and the
- 10:56I G E is another one, and so they're both in munological but it's
- 11:01the IgG is the one that we measure, and it's a slightly different pathway
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- 11:41these powerful methods. Okay, and then it's food intolerance. It just kind
- 11:46of in the middle or is that told more things think of things like lactose
- 11:50intolerance and stuff like that. So that's where that's another different kind of format
- 11:54again slightly in the in the middle of a good way of putting it,
- 11:58but probably am slightly the IgG in terms of it's an intolerant versus an immunological
- 12:03response. In terms of that the IG is and what does compliment mean?
- 12:11So yeah, so, so now come into our kind of specific bethificity or
- 12:15the specific nature of our test. And what we do is we measure not
- 12:20only the IgG, but the subclass is the IgG one through four. But
- 12:24we also measure compliment activation. So we're looking at two parts of your immune
- 12:30system. So there's the acquired immune system, which is the IgG, and
- 12:35then the innate immune system is the compliment activation, and that's the compliment that
- 12:39we measure. And what that does is to kind of simplify the bit is
- 12:43IgG is a great way of finding out which food you're exposed to, what
- 12:48you're consuming, and the compliment activation the innate pathway is an inflammatory response.
- 12:54So in essence, what we do is we try and work out what you're
- 12:58exposed to with the IgG, but then what we go on to do is
- 13:01measure of the food you're exposed to, which ones are causing you an inflammatory
- 13:05response, because if you think about it, an inflammatory response is the underlying
- 13:11cause of most of the symptoms that patients present with. So a lot of
- 13:16tests are out there, Michelle, which are just looking at that IgG pathway.
- 13:20And one of the reasons I got very excited about working with doctor Brent
- 13:24Dauville all those years ago was he didn't just stop at exposure because again,
- 13:28we all need to be exposed to foods let's be clear. But what he
- 13:33worked out was, let's not just look at what you're exposed to, because
- 13:37that would come up with a long list of foods and they're not all relevant
- 13:41in terms of what you'd need to eliminate to reduce the symptoms you present with.
- 13:45So he went on, and that's the brilliant of him to say,
- 13:48well, why don't we look at which foods are actually causing in innate response
- 13:52the compliment, which then gives you a way of really zeroing in on,
- 13:58frankly, a much smaller list of foods which is focused on the inflammatory response
- 14:01and so then correlates much more tightly with the symptoms of patient presents with.
- 14:07And so that's the big difference about our test, and it's the reason why
- 14:11we're the only test in the world that is patented because of doctor Duvall's brilliant
- 14:16looking at the IGGI the exposure, but then going on and look at the
- 14:20inflammation as well. So the great companies out there measuring IgG the limitation isn't
- 14:26them. It's that pathway because it's only telling you what you're exposed to.
- 14:31Oh is that what the alka and the every well or whatever that one every
- 14:35weell's look at that ALCAT is slightly different. It's looking at how your white
- 14:41lymphocyte cells swell. But the reality is is not multiple reasons why they swell,
- 14:46And so sometimes you know what I hear from providers is that's why that
- 14:50test, again very accurate, measuring that swelling of the white lymphocyte cells,
- 14:56but in reality, there's multiple reasons why they may swell. So you end
- 14:58up we've put a few bold positives. So that's the issue that it's again
- 15:03very accurate, but again there's multiple reasons why the white blood cells not only
- 15:09linked to food sensitivities. Yeah, and I think honestly, you have an
- 15:13obstacle or a challenge to face because the history of testing has been very spotty
- 15:20and and a lot of false positives that you know, people then take us
- 15:24kind of a generalized Okay, this is not really worth doing because I'm going
- 15:28to get a lot of information is going to scare me or make me go
- 15:31down a path that is inaccurate. So how do you overcome the history of
- 15:39testing food sensitivity testing? Yeah, and it's a very good point, Michelle,
- 15:46because again when I got involved in this area, I was like anyone
- 15:48else, you kind of you you look at Google or I think it was
- 15:52probably Yahoo back in ten years ago, but you look at Google and you
- 15:56kind of go, well, you know, what does it say about food
- 15:58sensitivity testing? And you know, you're right, there are some pretty negative
- 16:02articles because of that focus on the exposure versus the inflammation that we look at.
- 16:08And so from when I got involved in the business, you know,
- 16:11I did my due diligence to see how does it differ from some of those
- 16:15other companies out there, and for me again, you know, there's I
- 16:21think it's it's it's a pretty key thing that you know, if your business
- 16:25and your company and your product is based on sound science with some very good
- 16:30scientists around it, and then really what you need to then is you know,
- 16:33communicate better your message. That's an easier story to do versus if you've
- 16:37got poor technology to start with, doesn't matter how good your marketing spin is,
- 16:42it's going to fade away. And so I think the nicest thing with
- 16:45our technologies based on really sound patented technology with the gentleman that invented the first
- 16:51rapid HIV diagnostics. So from my standpoint, that's why I was so excited
- 16:56to get involved and own this business was because the very sound technology, brilliant
- 17:02scientists based around it as well, and from that place you can then explain
- 17:07the differences. As we were talking about earlier, it's not just measuring exposure,
- 17:12it's the brilliance of doctor Dorvill looking at the exposure, plus a compliment
- 17:18in terms of that inflammatory pathway that we described, so that helps you reduce
- 17:22those false positives. And equally, you know, when I got involved,
- 17:27there was only a handful of doctors running a test, but they were all
- 17:30telling me about these amazing outcomes they'd had from using the testing, so you
- 17:34know, it was very gratifying to think, well, wow, I wonder
- 17:38if we can take this to a larger number of providers versus where we were
- 17:42at the time that I got involved. So taking a deep dive into the
- 17:49actual testing, what first, let's start with inflammation. I think that term
- 17:55is bandied about, So why don't you define what is inflammation and how the
- 18:00oppression? No, they have inflammation, so I think you know, there's
- 18:04a there's a long list of symptoms that you know, we've now we've very
- 18:07thoughtunate. We've gone from probably just under ten providers to nearly ten thousand providers
- 18:14in the last ten years, so we've had some explosive growth in terms of
- 18:18the number of people running the test, and they you know, I'm often
- 18:22asking the providers and it's a great one of the highlights of my day that
- 18:26we do lunches with many providers most days and so talking to them about you
- 18:30know, success stories and to your question, how do they use the test
- 18:34and what are the types of symptoms, and so they'll talk about weight loss,
- 18:38they'll talk about kind of brain related issues like migrains, anxiety, they
- 18:45talk about arthritis, and so if you think about most disease states, the
- 18:49underlying cause a lot of them, the root cause them is an inflammatory response.
- 18:53So whether it's skin related that you know, all those things are inflammatory,
- 19:00and so by measuring the complement, we can get to that root cause
- 19:03of those different symptoms and identify if there's inflammation linked to your diet, we
- 19:10can help reduce that inflammation that you know, again we're never claiming we're going
- 19:15to cure anything, but if you can greatly reduce that inflammatory response which is
- 19:19causing that symptom, and what you would hope to see is a cessation or
- 19:23a great reduction excuse me, in the symptoms that that patient presents with.
- 19:30Yes, So I think that the issue for a lot of people that,
- 19:33like when we're talking differentiating between food allergies and food sensitivities is that it's more
- 19:38subtle. Food sensitivity is more subtle. The allergy, like you said,
- 19:44is more extreme, and so people can live their lives and that say,
- 19:48oh, I don't feel so well, but they don't know really the subtle
- 19:52reason is that they're reacting to certain of the foods that they eat on it
- 19:57probably on a daily basis, knowing like Blueton, for example, is a
- 20:02big, a big culprit dairy another culprit show. We'll talk about that at
- 20:07the moment, but I mean it's a great point. I mean, I'll
- 20:10give you just a brief example that I was talking to a doctor many years
- 20:15ago and he said, like, I'm not going to run your test,
- 20:17James, because I know I'm sensitive to eggs. I said, well,
- 20:19why don't you give it a whirl and just try And it's really interesting.
- 20:22He didn't come up for eggs. He came up for oranges. And so
- 20:26I said to myself, what do you have with those eggs every morning,
- 20:29doctor, he said, oranges, oranges something exactly. So again it's that
- 20:33point where sometimes you'll assume what you think it is, but until you t
- 20:37why guess, why not test to make sure you can make sure that you
- 20:41know you're actually eliminating the right food. And in his case he was you
- 20:45know he was closed, but you know, no cigar, as they say.
- 20:48So the idea is, what you want to do is make sure you
- 20:52test to identify. And I think that this is the great thing on an
- 20:56individualized basis, and I think we all recognize now there's no such thing as
- 21:00one size fits all in any walk of life. So what you want to
- 21:03do is try and make sure with medicine in particular, how do you individualize
- 21:08your task to make sure that as an individual, those results are unique to
- 21:14you. So you may be sensitive to eggs, I may be sensitive to
- 21:18dairy, but we need to know on an individualized basis which foods they are
- 21:22so we can eliminate those from our diet and help improve whatever the symptoms that
- 21:27we have that we present with. Well, I think there's a there's another
- 21:33part of this too, and that is that it can your food sensitivities can
- 21:37change. So let's say you do the chest in December and then you do
- 21:42another chest in June six months later, what have you found When people are
- 21:49testing even let's just say they've done the elimination, but now other those foods
- 21:56have disappeared on most of them, however, new ones appear. So you
- 22:03know, this is what I know in the past when I've done the doctor's
- 22:06data. They specters sell those tests, have food food sensitivity tests. They
- 22:12I could do them and and they change. So how do you deal with
- 22:17that, the fact that these food sensitivities to change. Yeah, I mean,
- 22:22I mean all of them look at slightly different, you know, elements.
- 22:25But I think what we see is that there's a common list of foods.
- 22:30And again, because we're running these multiple pathways, it helps in terms
- 22:36of the reproducibility, which is kind of what you're getting at I. You
- 22:40know, if I test it on Monday, when I get the same result
- 22:41kind of Friday, now Tuly you your immune your system is changing the whole
- 22:45time. But Jenny, what we see is a really good commonality again reproducibility,
- 22:52and part of that is again you know, I don't want to keep
- 22:56half halfing back. But it's you know, one of the things that excites
- 22:59me when I go to ball was when we run the test. You know,
- 23:03we've are testing and our manufacturing, our approach is under that real infects
- 23:07disease disease approach from doctor Doldan and his HIV background. So we run fifteen
- 23:15standards of controls patient to make sure the testing is highly accurate and highly reproducible,
- 23:21which I think is what you're getting at Michelle. And that's the big
- 23:22difference here is can you make sure that you're producing a test which is highly
- 23:26accurate and highly reproducible. And I think that was the thing that excited me
- 23:30when we got involved ten years ago, and we've only improved it over that
- 23:34time. So going back to the question about how do you know you have
- 23:37the symptoms that are causing these reactions? So you mentioned you know, the
- 23:44weight glass issue and the brain brain issues or brain fog or memory you know
- 23:51those kinds of you know, because of the gut brain connection. And then
- 23:56but what about within the GI tract itself? Mean, people do people have
- 24:02like, you know, the feeling of being bloated or what what are the
- 24:07signs that a certain food is causing you to have an influentflammatory reaction. I
- 24:14mean they're all I mean a diarrhea that all of those you know IBS type
- 24:18symptoms. In fact, we did a study on IBS on one hundred IBS
- 24:22patients. It was an IRB approved study, so again it went through a
- 24:27medical board to make sure that you know, we were doing it all the
- 24:30appropriate way. We took a hundred patients under the guidance of a general called
- 24:34doctor William SSP in Los Angeles. And so this study took a hundred patients,
- 24:41fifteen in the control, fifty in the intervention, and we tracked all
- 24:45those various symptoms that you talked about there and to see could we improve them
- 24:49by eliminating those foods from their diets. So we tested them on day one
- 24:52and then six months later, and we saw a dramatic reduction in the thing
- 24:57called their IBS severities or based on eliminating those foods. And in terms of
- 25:03that elimination debt that you talked about, so you went from identifying the foods,
- 25:07eliminating them and then retesting them, and we saw dramatic improvement in their
- 25:12IBS severity score and what we also meant measured at the same time as I
- 25:18think called high sensitive CRP, which for clinicians is a general marker of inflammation.
- 25:23And what was really encouraging for us is we saw that come down dramatically
- 25:30as well. So again not only by eliminating these foods do we see their
- 25:34symptoms improved, which is important from a patient perspective. We saw, for
- 25:38example, the number of days lost at work because again these IBS patients,
- 25:42the number of times they have to visit their providers is really high, so
- 25:48that came down. But more importantly, you know, from a scientific standpoint,
- 25:52their overall levels of inflammation as measured BYRP came down precipitously as well.
- 25:57So it was nice to see symptoms improving for the patient, but then as
- 26:02well in terms of what is that what how do you define that? When
- 26:04we looked at inflammation, we saw that come down directly as a correlation of
- 26:10that. So that's what we've seen with this test when we've done it in
- 26:14an independent study, and I think that's one of the things we're very proud
- 26:17of that we've done independent studies, because if you do it yourself or you
- 26:22know, you have your lead scientists as the lead lead author on these things,
- 26:25you're probably going to get the answer you're looking for. So it was
- 26:27nice to do independent studies to see that, you know, we could get
- 26:30that through independent physicians running the testing well, So just to confirm those terms
- 26:37so people understand. So so IBS means irritable vowel syndrome and CRP is C
- 26:45reactive protein C reactive proteins. Used a lot with pardio vascular testing too to
- 26:49see whether the you know, you should always be under one or one or
- 26:56below right, So that's a marker of inflammation. But it's more than just
- 27:00cardiovascular, as you've just explained. And you know, the other thing I
- 27:06noticed is that people who have food sensitivities often have acid reflux or gird I
- 27:12guess that's called gird um, you know. There they have problems with their
- 27:18digestion, and that in itself is it's got a it's a debilitating experience for
- 27:25anybody that when you eat something you don't feel well after you eat, instead
- 27:30of feeling nourished, which is what food. Food is your medicine. It's
- 27:33opposed to nourish you, not make you feel sick. So so all that
- 27:37you're doing, I honor you and congratulate your efforts to do this, you
- 27:41know, scientifically and with true medical expertise behind the science as well, and
- 27:51with ten thousand providers confirming that it works. I think that's a nice thing.
- 27:57It's it's nice. When we first got involved, we were doing some
- 28:00stuff through the insurance companies and the insurance industry is you know, is you
- 28:06know, don't regardless of how people view it, um, you know,
- 28:11some people will get things paid for automatically because it's covered on insurance. So
- 28:15for me, the gratifying thing is we're doing all these tests and people are
- 28:18paying out of pocket for it. So again a patients believe in it,
- 28:22and to your point, more importantly, providers do. So. Again it's
- 28:25not well, I'm going to run it because it's covered by my insurance.
- 28:27I don't really care. It's very much. You know, they're thinking about
- 28:30it, and they're and they're choosing the providers wisely who've gone and done the
- 28:34extra work to say, look, you know, let me seek out some
- 28:37of the tests that will help you move me from you know, let me
- 28:41be on on ten pills a day to you know, let's eliminate some of
- 28:44those drugs that I'm on and let me see if I can look as you
- 28:48mentioned, you know, food being my medicine and identify which foods actually my
- 28:52medicine versus which ones are actually causing me, you know, issues like you
- 28:56mentioned of good diarrhea and some of these other symptoms that come along with them.
- 29:02So, you know, James, it's really overwhelming when you're as the
- 29:07individual. I'm sure you can relate to this as you're not a medical doctor.
- 29:11You're you're you're a consumer just like the rest of us, even though
- 29:14you're running a company that's in the medical field. So I think you can
- 29:19be very compassionate to people. So you do know how overwhelming it is to
- 29:26make the right choices when you're trying to take responsibility and be proactive with your
- 29:32health. So do you have any advice or how would you guide people?
- 29:37And why and why should they do the KBMO tests as one of the protocols
- 29:42in that health regiment that they're going to be investing in. As you just
- 29:47said, many people are paying out a pocket for your testing. Yeah,
- 29:52I mean, I think what I found is that you know, we've been
- 29:55fortunate that we've I think over the last ten years has been a move to
- 29:57more pay understanding that you know, they need to take control of their own
- 30:03health and invest in their health. You know, as your ages and timers
- 30:06suggest, you know that you don't get there by accident. You get there
- 30:10by investing and being aware of what's on the market. And so what we've
- 30:12tried to do is partner with the right positions who you know, it's a
- 30:18great test, but my view is, you know, it goes from good
- 30:22to great by working with a good provider who can look at the supplements and
- 30:26other things that involved. So we're very much focused on the idea that you
- 30:29know, let's provide a good test and then some of the compliance tools around
- 30:33that and the provider network, which I think kind of brings it all in
- 30:38together because you know, as ever in life, it's very rarely one thing
- 30:42that you need to be working on. It's it's everything and around. It's
- 30:45lifestyle. It's you know, and lifestyle encompass to many things, isn't it.
- 30:51So the idea here was to think, how do we come up with
- 30:53a test, and how's the best route to kind of giving patients access to
- 30:57that, and our viewers. Let's do it through a good networker providers that
- 31:03has grown, you know, who are looking at these these kind of areas.
- 31:06And so that's how we've found the best way to do it is work
- 31:10within a provider network. And again, if patients are you know, are
- 31:14looking at you know, who's the right person to work with, they can
- 31:18contact us. And we've got an extensive networker providers out there now. And
- 31:22again we've got some people who we work with remotely. I can think of
- 31:26a lady called doctor Philkahina, who's, you know, one of our star
- 31:30providers. She's been doing this for ten years plus now. And on top
- 31:36of that, you know, she runs all our meal planning. So we
- 31:38provide these compliance tools for patients so they can get their results on their phone.
- 31:44They have a meal plan which we now individualize per patient. So again
- 31:48when you get your results, you've got something to follow. Because to your
- 31:52point in terms of things being overwhelmed overwhelming, Michelle, we keep our report
- 31:56to three pages. And that's not because doctor kind of round of things to
- 32:00say after three pages. That was because the most patients and most providers everyone's
- 32:06busy. We want to try and keep it so simple to understand and communicate
- 32:10that messaging to our clients. So the report is color coded red being bad,
- 32:15green being good. So again often and you know, I'll put my
- 32:20consumer hat on. You know, I've sat opposite doctors who kind of run
- 32:24through results and find numbers at me that frankly mean nothing to me. So
- 32:29that was one of my kind of things. Can we make this report easy
- 32:32for the layman like myself to understand versus going, I want to be the
- 32:37smartest guy in the room, I'm going to give you all these strange kind
- 32:39of spider webs and numbers up the ying yang which don't mean anything, not
- 32:44to the average consumer. And so that's why we've tried to do it,
- 32:46is to simplify it. So you know it was done by a PhD,
- 32:51but we want, more importantly for the ninety nine percent of the rest of
- 32:54us who aren't PhDs to be able to understand it. And so I think
- 32:58that's where as you say, not being a doctor is kind of helpful because
- 33:01I can look at it as a consumer and say, how can we give
- 33:05you a report that you might understand? Well, what's the first question I'm
- 33:08going to ask as a consumer Okay, you've told you've tested me for all
- 33:12these foods? What can I So that's why we put in place, you
- 33:15know, the meal plan, so they've got something they can actually follow and
- 33:19move forward on their journey to wellness or agelessness or timelessness. So that was
- 33:23the thinking behind, you know, our testing is make it simple for the
- 33:29patient to understand, because then you'll get good compliance. Because if we don't
- 33:32get compliance to your point, that's when patients get kind of a bit grumpy
- 33:37because they're going, I spent money on something, but I don't understand.
- 33:40Now I've got the results, what are the next pathways forward to actually turn
- 33:46that piece of paper into a meaningful change in my lifestyle. So so this
- 33:52is the you know, interesting question that I think a consumer has, at
- 33:58least I do a consumer. So how can a little prick of blood that
- 34:04you know, at the A form show, they put you put your finger
- 34:07out, they prick your finger and they put it on a card and that
- 34:10tells you so much information. How do you go from A to B to
- 34:15get that prick of blood to tell you one hundred and seventy six food sensitivities
- 34:22and then further to that now with your new products gut barrier panel, which
- 34:27we'll talk about. How can one little prick of blood tell you so much?
- 34:31Yeah, So it's interesting so that the blood cards that we use were
- 34:37first invented for infects disease testing as well as helstick testing, which is done
- 34:43in infant still today. So they use that way as a as a very
- 34:46convenient way of storing the blood. And then what we do is when that
- 34:52comes back to the lab, it goes for a process evolution, which basically
- 34:57means kind of taking that dehydrate example, and rehydrating it, and then we
- 35:01then take that sample and then and then run that in the in the testing.
- 35:06But again, if you think of things like twenty three and me,
- 35:07you're you're doing a boot, you know, a buckle swab on the inside
- 35:12of your mouth, You'll take a bit of spit and then you know,
- 35:14they come out with thousands of genes and piece of information there. So the
- 35:17healthcare industry is used to taking a kind of almost dehydrated sample, rehydrating it
- 35:24as it were, and some of the patients or amplifying that signal as they
- 35:29do in kind of the genetic world to kind of enable it to kind of
- 35:32give you the answers that we can. So that's where we were very fortunate
- 35:37again with Dr Dorwell, how do we create a easy to use sample,
- 35:42and now we do many Many of these kits are sent to patients at home
- 35:46to run the test at home, it gets sent back to us and then
- 35:50they can go and talk to their provided to review those results. So again
- 35:53it's as you say, it's an easy to do test, a little finger
- 35:57stick. It gets mailed back into us, the results get sent to the
- 36:00provider and then the provider can then review those with their patients. So again
- 36:05we try to make this as simple as we can and it's fascinating for me.
- 36:07We're always looking at are there other technologies and techniques that can enhance and
- 36:13improve that process even further, So we're constantly on the lookout for other ways
- 36:16of doing it than we're doing it now. But again it's a it's a
- 36:21very robust technology and it's you know, using things like Eliza plates and elect
- 36:25alsas which we make those plates here in the house. So again we've got
- 36:30a manufacturing facility which is done under FDA Register registration and ISO thirteen forty five,
- 36:37and then our two clear high complexity labs are under clear guidelines as well.
- 36:42So again it's a highly regulated industry that we work in, and again
- 36:46we like that environment because again it enables us to give I think, very
- 36:51accurate and reproducible results put out to our patients. And they're all the providers
- 36:55and more importantly their patients. What as just as in terms of results of
- 37:01over time with you know, ten thousand providers, you've obviously seen a number
- 37:05of different results. And what would you say if you want to make a
- 37:10list, what are the five most common food sensitivities that you see? Um,
- 37:17I mean the big three are eggs, milk, and wheat, and
- 37:22then they can vary from there, but again those are the there's probably six,
- 37:24but those are those are the three that I think of because we developed
- 37:29a rapid test and when we said, you know, what are the three
- 37:31things we should put on there, we said, let's do eggs, milk,
- 37:34and wheat because they're be synonymous in lots of things. And have found
- 37:37that to be a good grouping of of of the big three as it were,
- 37:42to kind of measure four. Now we measure for one hundred and seventy
- 37:45six and again we were thinking when we kind of expanded our panels to think
- 37:51about you know that if you think about, you know, how do people
- 37:54how are people exposed to some of these foods and so, and we measure
- 37:59color and additives now and what as well, because there's three different ways of
- 38:02doing it. Is it in a processed food, you know, is it
- 38:06in a supplement, or is it in a personal hygiene product? And so
- 38:09a good example of that is I was talking provider the other day and she
- 38:13said, you know, they had a nine year old boy who was very
- 38:15lethargic and they really couldn't work out, you know, what was what was
- 38:20going on. But we tested him for the colorings and additives and he came
- 38:25up really high for benzera acid, which turned out was in his shampoo conditioner
- 38:30and his mum's washing pattern. They eliminated the benzoa acid and within a couple
- 38:36of weeks he was back to being a normal nine year old bounty boy with
- 38:38plenty of energy. So I think the reason I mentioned that is a those
- 38:43colorings and additives are increasingly in processed foods, supplements, and personal hygiene products.
- 38:50In fact, I think I was reading an ask for the other day
- 38:52that said, you know a lot of patients who are you know, over
- 38:55eating or have obesity issues, fifty percent of the food that they can assuming
- 39:00is processed. So on that basis, you should really be measuring those colorings
- 39:05and additives that we include in all our pals because they're increasingly showing up in
- 39:10the in the in the food chain where they never were meant to. And
- 39:15a good example of that, you know, you think of the red dyes
- 39:17and things like red velvet cake that was originally invented by Bayer after World War
- 39:22Two to color plastics and with no concept that that would then end up,
- 39:27you know, all these years later being used for you know, consumed being
- 39:32consumed by patients, by patients in terms of in red velvet cake. So
- 39:36there's a other examples of that where you know, some of these colorings and
- 39:39additives have been i have been now in the food chain and you know they
- 39:45would never created to kind of come up with that way. So you have
- 39:50this new product, a gut barrier panel. Could you talk to us about
- 39:53nulin and occluding and all the aspects of what it means absolute and the reason
- 40:00we came up with looking at the gut Barret panel, which is an essence
- 40:04for consumes, is really a leaky gut panel. Was because when we when
- 40:08when I got it first got involved ten years ago, I'd wander the streets
- 40:13of New Hampshire at the time as I was looking after looking for some sales,
- 40:16and in between the kind of tattoo stores and the karate shops, there's
- 40:20quite a few natural paths in New Hampshire and so we were talking to them
- 40:22all about, you know, here's our food sensitivey test. You know,
- 40:25are you going to adopt this or not? Unfortunately lots of them did,
- 40:30but some of them would say to me, James, I don't test for
- 40:32food sensivities because I think my patient's got leaky gup. And so it kind
- 40:37of stuck in my mind that when you say, what do you mean you
- 40:38think are you testing for that? No, no, we think they've got
- 40:42leaky gup. So I thought, why don't we come up with a panel
- 40:45that enables them rather than to guess that that they can test for that.
- 40:49And so that's what we did, and we said and again, if you
- 40:52think about leaky gut and any of these gut issues, generally, it's a
- 40:57bit of a continuum. It's not just one single marker can occure us all.
- 41:00So we thought, let's put down a number of markers that can help
- 41:05us look at the kind of back gup barrier in terms of those type junctions
- 41:08and performance. And so we came up with three markers, as you mentioned.
- 41:13So we count of Canada, which we use as a kind of early
- 41:15kind of canary in the coal mine, is as indicator that there may well
- 41:20be some leaky gut going on. Then we developed our very own zonulin assay,
- 41:25which again looks at zonulin, which is a marker of how well those
- 41:30type junctions are functioning, so are they opening and closing. And the other
- 41:35great thing about zonulin is it's what they call a reversible marker. So if
- 41:39you've done some damage there or some issues with the right protocols, it can
- 41:44be it can be repaired and badly. We thought, you know, we've
- 41:46looked at an early stage marker, we've got the how well they're functioning,
- 41:52why don't we look at the structure of those type junctions as well. So
- 41:54we've started to measure occluding and so those are the kind of three markers that
- 42:00we measure and we look at them with two different kind of lens if it
- 42:04were. We look at IgA one and two, which is basically i.
- 42:08GA is I think called a secreatory marker, which means it's found localized in
- 42:13the gut. And so again we thought, let's look at IA as a
- 42:15localized marker, which is kind of early stage, so if any of those
- 42:20markers are elevated, then it's an earlier stage onset of what might be going
- 42:24on. And then we looked at the IgG in compliment, which we run
- 42:28on all our foods, to say that's more later stage and systemic, so
- 42:31it's gone probably beyond the gut at that point. So that's how we came
- 42:36up with this panel to give people thinking of leaky gup more of the continuum
- 42:40than a single marker is going to cure all. So we've found it's been
- 42:45an amazing time since we launched set in September. We've been on a very
- 42:50steep upward kind of trajectory since then, so I think providers and patients again
- 42:55are loving the concept. This has been almost two tests for the price of
- 42:59one. We've been very careful not to increase our pricing, and again we
- 43:02can do that because we develop and manufacture all the products in the house,
- 43:07so again we're not seeing some of the inflationary pressures that you just buy these
- 43:13tests from third parties. So again, because we do everything ourselves, that's
- 43:17enabled us to pass on a much more attractive proposition to our patients and the
- 43:22providers at the same price as we were when we were just looking at food
- 43:28sensitivities. Now you don't have a supply chain because you're vertically integrated. So
- 43:32yeah, that's that's a very important point. So some of the bigger companies
- 43:37are going, well, China is not going to letting us have what we
- 43:38need. That's not our problem. We're everything we have is here, and
- 43:44again we've worked very hard to make sure that we can. We're in were,
- 43:46as you say, vertically integrated to control the costs and kind of old
- 43:51fashioned, but let's do you know, let's look at everything locally so we
- 43:54can source everything locally, and we've tried to do that as much as we
- 43:58probably can. Okay, if you if if the individual, can you still
- 44:04hear me? Yep? Oh okay, because my power just went off.
- 44:08I don't know why we're having we're having issues here. The gremlins in your
- 44:15house today? Yeah, Tony, can you am? I? Okay?
- 44:21I think I think you and I are good, but I don't know if
- 44:22Tony can hear me? You're good? Oh? Okay, okay, I'll
- 44:27keep going there. My screen went black. Um okay, it says entering
- 44:31power save mode whatever that means. Um. So, because we're almost at
- 44:37the end, James, I want to cover a couple more things that are
- 44:40very important. If someone were to eliminate all the food sensitivities that come up
- 44:45on their chests with that automatically cure their other side of the gut barrier panel
- 44:52if they're showing leaky gut or at least the beginnings of leaky gut. Is
- 44:57that A Is that A one? Two steps? I mean, there's two
- 45:02different elements if you think about it. The foods are trying to identify which
- 45:07food to cause the inflammation. And again if you eliminate those foods, and
- 45:10you should bring down the in planetary response and then definitely see a cessation of
- 45:15the symptoms you're presenting with. When it comes to the gut barrier panel,
- 45:21we recommend looking at usually a kind of We've identified three really good companies chemical
- 45:28biotics, nutritional frontiers a neutrodyne who have excellent products they're going to help treat
- 45:34the leaky gut. So what we'd say, if any of the six markers
- 45:37on the leaky gup panel are elevated, then you know your torture provider,
- 45:43who will then kind of recommend one of these good gut healing protocols. And
- 45:46so that's been one of the great things is working with some of these real
- 45:51experts in the field of Okay, so we've identified the problem, what are
- 45:54some of the protocols we can help give to providers patients as well of those
- 46:00supplements that make sense because as you mentioned former shell, that could be again
- 46:05a very confusing field for patients in terms of trying to you know, work
- 46:09out which is the right supplement. So we've gone back to some of the
- 46:13best companies in the industry and said, what are the best supplements you would
- 46:16recommend if you're looking to treat inflammation via the food as well as look at
- 46:23the gut barrier panel in terms of trying to help patients, you know,
- 46:27pal the gut. So I think it's rather than a you know, do
- 46:30one then do two, it's almost like I'd say, look at both areas,
- 46:35and then the third one would be looking at some level of supplementation and
- 46:38working fourth one with a really good provider to help you attack these things on
- 46:44multiple fronts. We could you do us a favor and have your office send
- 46:47me the list in an email of those three companies and the products and the
- 46:54actual products like if it's a probiotic or or you know what everybody a product
- 47:00is that that would be good for people to know about. I'm going to
- 47:04put that on my website with our podcast if you'll have someone do that that
- 47:08way people can see it. And then again, Michelle, that might be
- 47:13a great one to talk through with doctor Silverman on the base do now you've
- 47:15got him coming up the next few weeks, because again he's he's a provider.
- 47:21You know, we're just we're just the loadly laboratory and sare so you
- 47:23know, he can he can help walk you through, you know, where
- 47:27it makes sense to use those various products. Yeah, and he likes Ortho
- 47:30Molecular. He already talked to me about that company. I don't know if
- 47:36you work with them at all, but I think I think there's some great
- 47:39products out there, so again he can certainly be excited. Well, this
- 47:43is why one of the reasons I'm asking is because I know from experience that
- 47:46probiotics that has you know, one of the worst records of getting through the
- 47:51gi tracks of the acid in the stomach, so it never gets so it's
- 47:54kind of people throw their money away. So I want to be sure that
- 47:59our viewers and listeners will know which of these the doctors like and the and
- 48:06the professionals like you know, are efficacious and they're not going to throw their
- 48:10money away, but they're going to get results, and they're going to get
- 48:14results. So if you can do that right now, I provide those three
- 48:17four years and said we've asked the experts, they're going to come up with
- 48:20one of the best products that they've come up with us. So we'll happily
- 48:23share those with you. And you're listening, Yeah, that would be great.
- 48:27You know. In Ageless in Time as we try to be not only
- 48:31generalized so that people get a big picture of information, but we also like
- 48:36to go very specific to protocols, to ways that you can take the steps
- 48:42that are going to follow the macro with the micro so to speak. So
- 48:46yes, we like to give concrete information to people, and we also have
- 48:52a segment of our website an icon called Michelle Recommends, and on there if
- 49:00it is if it is a company that does have product, for example,
- 49:04we will recommend if we're if we're convinced, we will recommend those products.
- 49:08And usually the guests, our guests will offer some kind of a consideration to
- 49:15our viewers. So all that is good. We're trying to integrate everything so
- 49:20people can we can make this an easy voyage and journey for people to to
- 49:25great health. All right, So because we're coming to the end, I
- 49:30want to be sure that we do ask you whether you want to offer anyone
- 49:37that's viewing and listening today or will be on the internet, anything to get
- 49:45them to go to some of the providers to get this test. So just
- 49:50give us a little bit of what you'd like to offer and what you'd like
- 49:52how you like to incentivize our our viewers on using your product. Again,
- 50:00as I said, we work kind of really through providers versus direct consumer.
- 50:05But having said that, we have an excellent provider in doctor Silka Heiner who
- 50:09I mentioned earlier, who does all the meal planning but has been is a
- 50:14doctor of nutrition in Germany and as I say, has been working in this
- 50:19field for twenty plus years. So what we would do is if you contact
- 50:23kbmode Diagnostics, we can link you up the Silker and then what we'll do
- 50:29is we'll give you for one of her packages of running the test and then
- 50:34reviewing the results. And we're happy to give a twenty percent off discount for
- 50:37anyone who who quotes ages some timeless the Silker, and then I'll make sure
- 50:44that we do a deal of twenty percent off any of the any of your
- 50:47patients who or all listeners rather who come on and kind of work with Silker.
- 50:52And so the best way to get hold of her is if you contact
- 50:55KBMOA info at kbmode Aagnostics dot com at KBMO Diagnosis dot com. I'm sure
- 51:05Michelle put that up on the website anyway, and then that way, and
- 51:07we'll give you the that code of ages and timeless if you quote that,
- 51:13then I'll make sure Silk does a twenty percent discount, okay. And then
- 51:16yeah, and when you give me that list to put on, Michelle recommends
- 51:19would you add her her name to that? Even though I know, yeah,
- 51:23we can we can give you doctor doctor Silka's details and then that you'll
- 51:29being good check. And then one more I did find out coincidentally that my
- 51:34physician in Beverly Hills, doctor Nina slash Jeff, which is sac hd ev
- 51:42users, has used your product you're testing, and that was exciting to me
- 51:47because I, you know, obviously didn't know you before I went to Las
- 51:51Vegas to the show, and then when I was chatting with them, they
- 51:54said, oh, yeah, we've been using their tests. So um.
- 51:59So, her number if people want to reach her and use her as a
- 52:05provider and ask for the KBMO test is area code three one zero seven seven
- 52:12seven seven five one one. And doctor Nina s achd Ev she's fabulous.
- 52:20She's really great with immune health and hormone health. Well she's an anti aging
- 52:27physician, so and I will add that to my website as well. Well.
- 52:32James, I knew the time would go by really fast, and sorry,
- 52:36sorry we couldn't do the video today. But I think it's all good
- 52:39and that we've covered a lot of ground and you've been great and very knowledgeable
- 52:45of course and helping people without there's no salesmanship. You don't need to sell
- 52:50this This product sells itself. And so that's the great that's the jack.
- 52:55That's a nice thing being a small private company, you know, it's it's
- 52:59all about my making sure that we can service and give good product services.
- 53:01You know, that's what drives us. It's you know, we've got a
- 53:05great team of people here. We're very fortunate that you know, we can
- 53:07employ some such smart team of good local people here who then can then impart
- 53:13that knowledge, you know, all around the world, Frank, is what
- 53:15we're doing now. So again we're very fortunate that we can offer these such
- 53:17great products and again, you know, we don't need to push them.
- 53:22It's one of those things that we've now got this great word of mouth because
- 53:24again the team does such a great job of looking after the clients that we
- 53:29have. So again it's a great privilege to be running this team. I
- 53:32think this is really the next step. You know, people are getting smarter
- 53:37about the responsibility of their own health and I think recognizing, i mean,
- 53:42artificial intelligence is going to become one of the big a telomere management, DNA
- 53:49management, stemselves, all these things are so much more technologically based, and
- 53:53people are going to have so much more information through the internet available to you
- 54:00know, to avoid the pitfalls and try to take the steps that are going
- 54:05to work, like like food sensitivity testing. It's a it's a baseline really
- 54:10because eighty percent of our immune system is in our GI track. So if
- 54:15you don't focus on your your gut, you're you're maybe just skirting the main
- 54:21culprit for your illness. And if you can just fix your gut, you
- 54:24might find, in fact fact probably will find that other things symptoms that you
- 54:30have, will will clear up. So I think I think, I think
- 54:35you hit it on the head, Michelle. It's like if you can focus
- 54:37on some of those basics, like what you consume and again yeah, I
- 54:40don't even complicate it beyond that, and then work out what those are damaging
- 54:45or actually give to your immune system, and you're going to get a long
- 54:47way to age just in time myself. And I love that you keep giving
- 54:52me a plug. Thank you. Well. You know, when I when
- 54:53I created this podcast three years ago, it really was with that intention that
- 55:00people could live aipelessly and timelessly as long as they take the proper steps,
- 55:06and that requires information is power, and that requires giving every week that we
- 55:10do this information that's going to empower you to be the best version of yourself
- 55:16and to live a long and healthy life. Who wants to live a long
- 55:20life if you're not healthy. Absolutely, So thank you so much, James.
- 55:24I really appreciate your being much pleasure my budget. Thank you for giving
- 55:28me the opportunity to speak to your very knowledgeable base. I thank you.
- 55:31And I'm supposed to tell you all today that you're supposed to I never think
- 55:38to even sell my podcast, but I guess you're supposed to hit the subscribe
- 55:42button that we're going to have on the screen if you want to keep knowing
- 55:46more of our podcasts and when we're producing a new one. And also you
- 55:52can hit the bell, ring the bell if you like what you heard today.
- 55:57So yeah, I guess I'm not very alz about this, but I
- 56:01you know, I want people. I want as many people as possible to
- 56:05avail themselves of the information that we provide through the guests like James White,
- 56:10who are so gracious to give us their time and share with us their knowledge.
- 56:15So thank you very much everybody, and have a beautiful day, take
- 56:20care. Thank you all.