Latest / Sid & Friends In The Morning / Dr. Peter Michalos | Offers Expert Opinion on Efforts to Significantly Increase Human Longevity

Transcript

Dr. Peter Michalos | Offers Expert Opinion on Efforts to Significantly Increase Human Longevity · Sid & Friends In The Morning

• 0:00
  Speaker 1: Dr. Peter Michalos, and he has a new book out too,
• 0:03
  Speaker 1: and we'll talk about that. But I guess, you know
• 0:07
  Speaker 1: how many phone calls, you know how many texts I
• 0:09
  Speaker 1: get a week? Thank you for all the advice, and
• 0:13
  Speaker 1: we're going to live longer. Dr. Peter, how are you today?
• 0:17
  Speaker 2: I'm doing great, John. It's great to be with you
• 0:19
  Speaker 2: this morning to share some more great information coming out
• 0:23
  Speaker 2: from around the world on anti-aging and longevity.
• 0:27
  Speaker 1: Tell us, Dr. Peter, tell us, you know, me and
• 0:30
  Speaker 1: you have discussed it in length over the weekend and
• 0:33
  Speaker 1: the three billionaires that are trying to want to live longer.
• 0:39
  Speaker 1: And I'm telling people that if you have a baby
• 0:42
  Speaker 1: right now, guaranteed 120 and maybe someday 150. And tell
• 0:44
  Speaker 1: us that. the gene within the gene that helps, that
• 0:56
  Speaker 1: recreates our youth.
• 0:59
  Speaker 2: Well, this month on the cover of Time magazine is Dr. Yamanaka,
• 1:04
  Speaker 2: who is a surgeon in Japan, and he received the
• 1:06
  Speaker 2: Nobel Prize, and he found that each one of our
• 1:10
  Speaker 2: cells has the software for the younger version of our cells.
• 1:15
  Speaker 2: And what he discovered are these Yamanaka factors called the O, S,
• 1:19
  Speaker 2: and K factors. And when they gave those factors to
• 1:24
  Speaker 2: blind mice in the glaucoma model and blind apes, they
• 1:29
  Speaker 2: reversed blindness. And then they gave those factors... to wild
• 1:34
  Speaker 2: mice at Stanford University, and they lived 109% longer, which
• 1:38
  Speaker 2: is an extra 200 days, which is the equivalent of
• 1:41
  Speaker 2: 34 human years. And what these factors do is they tell,
• 1:44
  Speaker 2: it's called epigenetic reprogramming. It tells your DNA, listen, heal, repair,
• 1:51
  Speaker 2: and go back to a younger stage. Now, if you
• 1:54
  Speaker 2: go back too far, it becomes a cancer cell. And
• 1:57
  Speaker 2: they figured out The original factors were four, and then
• 2:00
  Speaker 2: they would give cancer to cells. But then when they
• 2:03
  Speaker 2: only gave three of the factors, which was discovered in
• 2:07
  Speaker 2: a lab by Dr. Woon Lee in David Sinclair's lab
• 2:12
  Speaker 2: at Harvard, and they found that they were able to partially...
• 2:16
  Speaker 2: tell yourselves, go back 10 years, go back 20 years.
• 2:20
  Speaker 2: And the first human who was blind was injected on
• 2:23
  Speaker 2: June 9th, 2026 this year. And it's really exciting. The
• 2:27
  Speaker 2: medicine's called ER100 and they've done 18 patients. And any
• 2:32
  Speaker 2: day now we're going to hear about the results. And
• 2:34
  Speaker 2: this is really going to change medicine, change the way
• 2:38
  Speaker 2: we approach healthcare. And basically it's like, uh, stem cells.
• 2:45
  Speaker 2: I mean, we start off as a, basically when we're conceived,
• 2:49
  Speaker 2: we start off as a stem cell and those stem
• 2:52
  Speaker 2: cells then become who we are today, which is 40
• 2:54
  Speaker 2: trillion cells that continue to recycle and continue to specialize
• 2:59
  Speaker 2: and become heart, brain, lungs. So harnessing this power of
• 3:04
  Speaker 2: getting back to the original healing cells, because stem cells
• 3:08
  Speaker 2: are our natural repair cells. And so, They're basically the
• 3:12
  Speaker 2: handyman that goes around and fixes everything. And, you know,
• 3:16
  Speaker 2: when people have cancer, they do bone marrow transplant. That's
• 3:18
  Speaker 2: basically just giving you stem cells, and then they know
• 3:21
  Speaker 2: where to go and how to heal. And what this
• 3:24
  Speaker 2: OSK Yamanaka factors, they tell the cells, lay, heal, repair,
• 3:30
  Speaker 2: go back to your 20-year-old John Katsimatidis or Peter Michalos.
• 3:35
  Speaker 2: And then we're probably, in a couple of years, if
• 3:38
  Speaker 2: things go well with this, we're going to go into
• 3:40
  Speaker 2: these regeneratives. clinics and get an infusion of these Yamanaka factors,
• 3:46
  Speaker 2: and they attach them to something called an adenovirus, which
• 3:49
  Speaker 2: is like a common cold virus, and that's how it
• 3:51
  Speaker 2: gets into the body and into the cells. So it's
• 3:54
  Speaker 2: a fascinating area. That's why Jeff Bezos raised $ 3 billion
• 3:58
  Speaker 2: and started Altos Labs out in California, and several other
• 4:04
  Speaker 2: people in that tech world, like Sam Altman, they've put
• 4:07
  Speaker 2: money into another company that's going to do it for
• 4:09
  Speaker 2: Alzheimer's disease and to tell the brain cells to go
• 4:13
  Speaker 2: back to it.
• 4:14
  Speaker 1: So we're moving at warp speed in medicine. That's bottom line.
• 4:21
  Speaker 1: And so over the next 10, 20 years, at what
• 4:26
  Speaker 1: point do we make a big breakthrough? You said we
• 4:29
  Speaker 1: have 50 trillion.
• 4:31
  Speaker 2: 40 trillion cells in our body. That's a lot of cells.
• 4:38
  Speaker 1: Even for the high-speed computers.
• 4:40
  Speaker 2: It is, it is. And another really fascinating study, because
• 4:43
  Speaker 2: you and I talk a lot about wearables and the watches.
• 4:47
  Speaker 2: They just looked at, this is a brand new study
• 4:49
  Speaker 2: that just came out, breaking news on WABC. It's a
• 4:52
  Speaker 2: 2026 study that was published in the European Journal of
• 4:59
  Speaker 2: Preventive Cardiology. And what they found, they looked at all
• 5:03
  Speaker 2: the wearables and they studied, and people they found who
• 5:07
  Speaker 2: had eight hours of sleep up to nine hours on
• 5:11
  Speaker 2: the wearables. They looked at all the data and they
• 5:15
  Speaker 2: had at least 140 minutes a week of good exercise.
• 5:19
  Speaker 2: Their risk and they also reported that they had good nutrition,
• 5:24
  Speaker 2: Mediterranean diet, those people had a 57% reduction in the
• 5:29
  Speaker 2: incidence of heart attacks. Now, that's a big deal, too.
• 5:32
  Speaker 2: And that's now because with all this data we have
• 5:34
  Speaker 2: with AI, it can pull it together just from people's
• 5:37
  Speaker 2: wearable watches, and they did this in England. So sleep,
• 5:42
  Speaker 2: physical activity, and nutrition.
• 5:44
  Speaker 1: So what's the minimum sleep then, again?
• 5:47
  Speaker 2: If you can get eight to nine hours. But sometimes
• 5:51
  Speaker 2: when we- That's honest.
• 5:52
  Speaker 3: Yeah, I don't get it. I think between John and myself,
• 5:54
  Speaker 3: maybe we get eight hours combined. Hey, doctor, have you
• 5:57
  Speaker 3: ever heard the joke, why do Jewish men die before
• 6:02
  Speaker 3: their wives?
• 6:03
  Speaker 2: Yes, because they want to. Yes.
• 6:05
  Speaker 3: Very, very, very good doctor.
• 6:07
  Speaker 1: You're an anti-Semitic.
• 6:09
  Speaker 2: He also told me that was Mr. Bernstein in a
• 6:11
  Speaker 2: wheelchair who was 93. He told me, and why is
• 6:14
  Speaker 2: divorce so expensive? I said, I don't know, Mr. Bernstein.
• 6:16
  Speaker 2: It's worth it. It's worth it. By the way, it's funny.
• 6:19
  Speaker 3: I think we know the same guy. He told me
• 6:22
  Speaker 3: the same joke.
• 6:23
  Speaker 2: No, but the best one was Mrs. Heyman from Brooklyn
• 6:25
  Speaker 2: who told me that, hey, kid, it's no dress rehearsal.
• 6:29
  Speaker 2: Enjoy the visit on the planet. That's why people have
• 6:31
  Speaker 2: to keep listening to WABC to stay healthy. And another
• 6:34
  Speaker 2: fascinating study in Britain at Oxford found that if you
• 6:38
  Speaker 2: lower your blood pressure just by five millimeters of mercury,
• 6:42
  Speaker 2: that reduces your overall major cardiovascular risk.
• 6:47
  Speaker 1: Tell us the blood pressure, because I have one of
• 6:50
  Speaker 1: those blood pressure machines that I put on my wrist,
• 6:54
  Speaker 1: and I'm tired of them saying, you're abnormal. Okay, so
• 7:00
  Speaker 1: what is the ideal blood pressure? I'm over 70. What
• 7:07
  Speaker 1: is the ideal blood pressure?
• 7:09
  Speaker 2: Well, ideal is the 120 over 80. I have 120
• 7:10
  Speaker 2: over 65. That's really good. That's excellent. The thing is,
• 7:18
  Speaker 2: it's how you do it. You have to be sitting
• 7:20
  Speaker 2: in a chair. Your arm needs to be extended straight
• 7:23
  Speaker 2: out on a desk, not bent at heart level. And
• 7:26
  Speaker 2: then you have to keep, whenever you check your pressure,
• 7:28
  Speaker 2: you've got to do it in the same position. If
• 7:30
  Speaker 2: you have the one on the wrist and you bend
• 7:32
  Speaker 2: your wrist even slightly, that alters it and gives you
• 7:36
  Speaker 2: a falsely elevated one. But what was fascinating about this
• 7:40
  Speaker 2: study is that for every 5 millimeters that we kept
• 7:43
  Speaker 2: it closer to the normal amount, They found that it
• 7:47
  Speaker 2: reduced stroke by 13%, heart failure 13% less, ischemic heart
• 7:52
  Speaker 2: disease 8% less, and the overall death rate was 5% less.
• 7:56
  Speaker 2: So controlling blood pressure, and you and I have talked
• 7:59
  Speaker 2: about natural ways to control blood pressure too, just eating beets,
• 8:03
  Speaker 2: for example. Like I sometimes, if my blood pressure is
• 8:06
  Speaker 2: a little high and my regular medicine doesn't control it,
• 8:09
  Speaker 2: I just take a beet supplement, and it's fascinating. In
• 8:11
  Speaker 2: an hour, it drops like 10 points.
• 8:13
  Speaker 1: That's very true. I love these.
• 8:16
  Speaker 3: Doctor, we have right now medications that are widely prescribed
• 8:23
  Speaker 3: that are actually helping to do what like the Jeff
• 8:26
  Speaker 3: Bezos experiments and so on. And they're helping people to
• 8:30
  Speaker 3: live closer to the age of 100. Things like metformin, rapamycin.
• 8:37
  Speaker 3: You have all the GLP-1s now that just it seems
• 8:40
  Speaker 3: like almost everybody in the whole country has.
• 8:43
  Speaker 1: Is on.
• 8:44
  Speaker 3: Trump actually did something fantastic, and he put a price
• 8:49
  Speaker 3: limit that, what did he call that, the most favored
• 8:53
  Speaker 3: nation pricing onto it, as well as those SGLT2s. These
• 8:58
  Speaker 3: are all things that are helping Americans to live longer,
• 9:02
  Speaker 3: or I should say helping the world to live longer.
• 9:04
  Speaker 2: Yeah. Well, you mentioned rapamycin. I would try to avoid
• 9:07
  Speaker 2: that because that is very mixed and it weakens your
• 9:10
  Speaker 2: immune system. So people have to be very careful. A
• 9:13
  Speaker 2: lot of people who are pushing rapamycin are not pushing
• 9:15
  Speaker 2: it as much anymore because that tends to weaken the
• 9:19
  Speaker 2: immune system, makes you more susceptible to infection. So I
• 9:22
  Speaker 2: don't think the data on rapamycin is that good. And
• 9:26
  Speaker 2: I personally would stay away from it. And my wife
• 9:29
  Speaker 2: was an anti-aging specialist who's been doing this for a
• 9:31
  Speaker 2: long time. It's something that you have to be very
• 9:35
  Speaker 2: careful of, rapamycin. But yes, metformin definitely helps control blood
• 9:40
  Speaker 2: glucose and controls fasting insulin levels because they found out
• 9:45
  Speaker 2: that fasting insulin levels, when they rise, that promotes cancer
• 9:48
  Speaker 2: because it pushes glucose into cells. And that's why sugar
• 9:52
  Speaker 2: is not good and it feeds cancer. And that's probably
• 9:55
  Speaker 2: how metformin works, by keeping your fasting insulin levels normal.
• 9:59
  Speaker 2: Because you can have a normal blood sugar and a
• 10:01
  Speaker 2: normal hemoglobin a1c but it's being artificially kept there by
• 10:05
  Speaker 2: rising fasting insulin levels and many doctors and insurance companies
• 10:09
  Speaker 2: won't pay for a fasting insulin blood test but that's
• 10:12
  Speaker 2: actually one of the key isn't.
• 10:13
  Speaker 3: It also true though that the metformin actually helps uh
• 10:17
  Speaker 3: within which to keep the amylase off the brain.
• 10:21
  Speaker 2: It helps a lot of different things because, again, because
• 10:24
  Speaker 2: they think that part of Alzheimer's is like a type
• 10:27
  Speaker 2: 3 diabetes and insulin resistance. So that's how it affects.
• 10:31
  Speaker 2: And a recent study even came out because they used
• 10:33
  Speaker 2: to think metformin just works in the gut. They found
• 10:35
  Speaker 2: it works on the hypothalamus in the brain to help
• 10:38
  Speaker 2: control blood sugar. So metformin has been around for 50-plus years.
• 10:43
  Speaker 2: It's actually based on the plant of the French lilac,
• 10:46
  Speaker 2: and it does– But that's why we dedicated an entire
• 10:49
  Speaker 2: chapter on a new book coming out next week called
• 10:52
  Speaker 2: The Death of Aging, 522 pages, summarizing all the literature
• 10:56
  Speaker 2: from around the world on all these different topics we
• 10:59
  Speaker 2: just mentioned. But staying healthy is very important. We're also
• 11:03
  Speaker 2: going to hear now because of the administration now they're
• 11:06
  Speaker 2: allowing stem cells. It's public information in Vanity Fair that
• 11:10
  Speaker 2: Secretary Kennedy received stem cells to help him with his
• 11:14
  Speaker 2: voice situation. And that was done by Dr.
• 11:17
  Speaker 1: Chadwick Padromos.
• 11:17
  Speaker 2: He sounds a lot better. Yeah, Dr. Chadwick Padromos treated him,
• 11:21
  Speaker 2: and he did very well. And now they're starting to
• 11:23
  Speaker 2: allow one of the greatest stem cell scientists called Bob Hariri,
• 11:27
  Speaker 2: who's an MD, PhD, who trained at Cornell, who has
• 11:32
  Speaker 2: a company called Cellularity. They're using stem cells, and they
• 11:36
  Speaker 2: collect them. For example, when you have a child, they
• 11:38
  Speaker 2: save the placenta and the umbilical cord. And those are, again,
• 11:41
  Speaker 2: the stem cells are your natural repair cells. and you
• 11:44
  Speaker 2: save them, and they're giving it to people for various conditions,
• 11:48
  Speaker 2: and they're helping them, and we're learning more about that,
• 11:52
  Speaker 2: and we're going to be hearing and allowing more of
• 11:54
  Speaker 2: that in the United States. Now people have to fly
• 11:57
  Speaker 2: off to other countries to get those things, but now
• 12:00
  Speaker 2: because of Operation Warp Speed, it's amazing the access that
• 12:04
  Speaker 2: people have to these medications. And as Mr. Cohn was
• 12:07
  Speaker 2: referring to, what they did with the price controls on medicines,
• 12:11
  Speaker 2: like there's a medicine called PSK9 inhibitors for cholesterol. They
• 12:15
  Speaker 2: actually reverse blockages. So that's amazing. A Cleveland Clinic study
• 12:19
  Speaker 2: showed that. A Cedars-Sinai in California showed that. It's another
• 12:23
  Speaker 2: class of an injectable drug. cholesterol medicine. They even have
• 12:27
  Speaker 2: ones that are just twice a year and once a
• 12:29
  Speaker 2: year and a lot of the early work.
• 12:31
  Speaker 1: Medicine at warp speed. Dr. Peter, thank you for coming
• 12:34
  Speaker 1: on and I want to have a one hour special
• 12:37
  Speaker 1: just talking about your book and we'll do that soon. Dr. Peter,
• 12:42
  Speaker 1: keep going. Live long and prosper. I'll meet you at
• 12:45
  Speaker 1: the age of 100.
• 12:47
  Speaker 2: Thank you, John. Think positive and test negative and keep
• 12:50
  Speaker 2: listening to the great WABC.
• 12:52
  Speaker 1: Thank you so much.
• 12:54
  Speaker 4: Thanks for listening to Sid and Friends in the Morning.
• 12:57
  Speaker 4: You can hear Sid and Friends in the Morning weekday
• 13:00
  Speaker 4: mornings at 6. Share it with your friends and listen
• 13:04
  Speaker 4: anytime at WABCradio.com and download the WABC Radio app. Hit
• 13:10
  Speaker 4: that subscribe button on all major podcast platforms. Plus, follow
• 13:14
  Speaker 4: WABC on social, on Instagram, TikTok, Facebook, and X. See
• 13:19
  Speaker 4: you next time for a new episode so you never
• 13:22
  Speaker 4: have to wonder.
• 13:23
  Speaker 3: What the heck is going on here?